Nicotinic Agonists
- Name
- Nicotinic Agonists
- Accession Number
- DBCAT000445
- Description
Drugs that bind to and activate nicotinic cholinergic receptors (RECEPTORS, NICOTINIC). Nicotinic agonists act at postganglionic nicotinic receptors, at neuroeffector junctions in the peripheral nervous system, and at nicotinic receptors in the central nervous system. Agents that function as neuromuscular depolarizing blocking agents are included here because they activate nicotinic receptors, although they are used clinically to block nicotinic transmission.
- Drugs
Drug Drug Description Nicotine A stimulatory alkaloid found in tobacco products that is often used for the relief of nicotine withdrawal symptoms and as an aid to smoking cessation. Varenicline A partial agonist at nicotinic acetylcholine receptors used as an aid in smoking cessation. Lobeline Investigated for use/treatment in addictions. GTS-21 Investigated for use/treatment in alzheimer's disease and schizophrenia and schizoaffective disorders. Epibatidine Not Available Encenicline Encenicline has been investigated for the treatment of Cognition, Schizophrenia, Alzheimer's Disease, Cardiac Repolarization, and Central Nervous System Diseases. - Drugs & Drug Targets