Name
Pyrazines
Accession Number
DBCAT000459
Description

A heterocyclic aromatic organic compounds with the chemical formula C4H4N2.

Drugs
DrugDrug Description
BortezomibA proteasome inhibitor used to treat multiple myeloma in patients who have not been successfully treated with at least two previous therapies.
PyrazinamideAn antituberculosis agent used as a component of tuberculosis (TB) treatment.
EszopicloneA sedative-hypnotic used in the treatment of insomnia, improving both the latency phase and the maintenance phase of sleep.
AmilorideA pyrizine compound used to treat hypertension and congestive heart failure.
Drugs & Drug Targets
DrugTargetType
BortezomibCytochrome P450 3A4enzyme
BortezomibCytochrome P450 2C19enzyme
BortezomibCytochrome P450 1A2enzyme
BortezomibCytochrome P450 2D6enzyme
BortezomibCytochrome P450 2C9enzyme
BortezomibProteasome subunit beta type-5target
BortezomibProteasome subunit beta type-1target
BortezomibP-glycoprotein 1transporter
BortezomibSolute carrier organic anion transporter family member 1B3transporter
PyrazinamideXanthine dehydrogenase/oxidaseenzyme
PyrazinamideFatty acid synthetasetarget
PyrazinamideAldehyde oxidaseenzyme
EszopicloneCytochrome P450 3A4enzyme
EszopicloneGamma-aminobutyric acid receptor subunit alpha-1target
EszopicloneGamma-aminobutyric acid receptor subunit alpha-2target
EszopicloneGamma-aminobutyric acid receptor subunit alpha-3target
EszopicloneGamma-aminobutyric acid receptor subunit alpha-5target
EszopicloneCytochrome P450 2C8enzyme
EszopicloneGABA(A) Receptortarget
AmilorideAmiloride-sensitive sodium channel subunit betatarget
AmilorideAcid-sensing ion channel 1target
AmilorideAmiloride-sensitive amine oxidase [copper-containing]target
AmilorideAmiloride-sensitive sodium channel subunit alphatarget
AmilorideAmiloride-sensitive sodium channel subunit gammatarget
AmilorideSodium/hydrogen exchanger 1target
AmilorideAcid-sensing ion channel 2target
AmilorideAmiloride-sensitive sodium channel subunit deltatarget
AmilorideUrokinase-type plasminogen activatortarget
AmilorideSolute carrier family 22 member 2transporter
AmilorideSolute carrier family 22 member 4transporter
AmilorideAmiloride-sensitive amine oxidase [copper-containing]enzyme
AmilorideAmiloride-sensitive amine oxidase [copper-containing]enzyme