4-Hydroxycoumarins

DBCAT000640Pharmacologic class

Substances found in many plants, containing the 4-hydroxycoumarin radical. They interfere with vitamin K and the blood clotting mechanism, are tightly protein-bound, inhibit mitochondrial and microsomal enzymes, and are used as oral anticoagulants. A DrugBank category of 5 drugs. 5 of them are approved.

Also known as: 4 Hydroxycoumarins
Drugs: Acenocoumarol
Dicoumarol
Ethyl biscoumacetate
Phenprocoumon
Warfarin

What you can answer from here — as of August 24, 2016

5DrugsEach linked to its full drug card

Listed above

5Drug targetsEvery drug–target pair in the class, with bond type

759Marketed productsAcross the regions we cover, with dosage forms and routes

2Routes of administrationHow the drugs in this class are given

Which targets do 4-Hydroxycoumarins share, and which companies have late-stage candidates in this class?

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