Polysaccharides

Name
Polysaccharides
Accession Number
DBCAT000669
Description

Not Available

Drugs
DrugDrug Description
Antihemophilic factor, human recombinantA form of recombinant coagulation Factor VIII used to treat hemophilia A, von Willebrand disease, and Factor XIII deficiency.
AcarboseAn alpha-glucosidase inhibitor used in adjunctly with diet and exercise for the management of glycemic control in patients with type 2 diabetes mellitus.
ArdeparinFor prevention of deep vein thrombosis, which may result in pulmonary embolism, following knee surgery.
InulinHistorically used in an important medical test of renal function, specifically a measure of glomerular filtration rate. Sometimes used to help relieve symptoms of diabetes mellitus - a condition characterised...
Pentosan polysulfateA sulfated pentosyl polysaccharide used to treat bladder pain and discomfort due to interstitial cystitis.
IcodextrinAn iso-osmotic solution used for continuous peritoneal dialysis or automated peritoneal dialysis.
IrinotecanAn antineoplastic enzyme inhibitor used to treat metastatic carcinoma of the colon or rectum.
Hydroxypropyl celluloseA cellulose ether used to treat dry eyes.
Iron DextranAn iron supplement used to treat iron deficiency in patients who cannot take oral iron.
QuinidineA medication used to restore normal sinus rhythm, treat atrial fibrillation and flutter, and treat ventricular arrhythmias.
HeparinAn anticoagulant indicated for thromboprophylaxis and to treat thrombosis associated with a variety of conditions such as pulmonary embolism and atrial fibrillation.
SucrosofateNot Available
CellobioseA disaccharide consisting of two glucose units in beta (1-4) glycosidic linkage. Obtained from the partial hydrolysis of cellulose. [PubChem]
MaltotetraoseNot Available
Trehalose-6-PhosphateNot Available
CellotetraoseNot Available
beta-D-galactopyranosyl-(1->4)-beta-D-galactopyranoseNot Available
SucroseA nonreducing disaccharide composed of glucose and fructose linked via their anomeric carbons. It is obtained commercially from sugarcane, sugar beet (beta vulgaris), and other plants and used extensively as...
MaltoseA sugar used as a sweetener and an inactive ingredient in drug products.
AllolactoseNot Available
LactoseAn additive and filler found in various products to maintain structure and consistency.
AllosamidinAllosamidin exhibits extremely potent inhibitory activity against chitinases from a number of sources, particularly from Candida albicans, and can be utilized as potent antifungal agent.
EritoranInvestigated for use/treatment in sepsis and septicemia.
PI-88Investigated for use/treatment in hepatocellular carcinoma, liver cancer, melanoma, and multiple myeloma.
IT-101Investigated for use/treatment in cancer/tumors (unspecified) and solid tumors.
Pentaerythritol tetranitrateUsed for the treatment of angina pectoris .
SugammadexA modified gamma cyclodextrin used to reverse neuromuscular blockade induced by vecuronium bromide and rocuronium bromide which are agents used for anesthesia.
SulodexideA drug used to treat chronic venous ulcers in the legs.
SemuloparinInvestigated for use/treatment in thrombosis.
IdraparinuxInvestigated for use/treatment in thrombosis, venous thromboembolism, strokes, heart disease, and atrial fibrillation.
E5531Investigated for use/treatment in sepsis and septicemia.
DanaparoidA heparinoid with anticoagulant and antithrombotic activities used for the treatment of acute episode of Heparin-Induced Thrombocytopenia (HIT), and for prophylaxis in patients with a history of HIT.
Sodium cellulose phosphateSodium cellulose phosphate is used to treat hypercalcemia and hypercalciuria. It has been used to prevent kidney stones. This compound is an ion-exchange resin that can not be absorbed by...
DalteparinA low molecular weight heparin used for the prophylaxis of thrombotic events in certain patients and prevent acute cardiac ischemic events in patients with unstable angina and non-Q-wave myocardial infarction.
TinzaparinA low molecular weight heparin used for the treatment of acute symptomatic deep vein thrombosis with or without pulmonary embolism when administered in conjunction with warfarin.
NadroparinA low molecular weight heparin used for the prophylaxis of thrombotic events and deep vein thrombosis, and prevent unstable angina and non-Q-wave myocardial infarction.
Hyaluronic acidA glycosaminoglycan used for the relief of joint pain, wound healing, ophthalmologic treatment, cosmetic treatment, and various other applications.
Ferric carboxymaltoseAn iron replacement therapy used to treat iron deficiency anemia in adults with intolerance or inadequate clinical response to oral iron or those who have non-dialysis dependent chronic kidney disease.
Hydroxyethyl StarchA plasma volume substitute used to treat and prevent hypovolemia.
PentastarchA plasma volume expander used as an adjunct in the management of shock due to hemorrhage, surgery, sepsis, burns or other trauma.
Iron sucroseAn compound used as a source of iron in patients with iron deficiency anemia associated with chronic kidney disease (CKD).
DextranA low molecular weight dextran used as an adjunctive treatment of shock or impending shock due to hemorrhage, burns, surgery or other trauma, as well as the prophylaxis of venous thrombosis and pulmonary embolism during high-risk medical procedures.
BemiparinAn ultra-low molecular weight heparin (ultra-LMWH) used to prevent thromboembolism following surgery and extracorporeal clotting during dialysis.
ReviparinBy the FDA, reviparin is indicated for the treatment of deep vein which may lead to pulmonary embolism in pediatric patients. It is also indicated for the long-term treatment of...
ParnaparinA low molecular weight heparin (LMWH) used to prevent blood clots, specifically deep vein thrombosis.
CertoparinA low molecular weight heparin (LMWH) used to prevent blood clots, specifically deep vein thrombosis.
Chondroitin sulfateChondroitin sulfate, used with glucosamine, is indicated to alleviate pain and inflammation from primary osteoarthritis. This supplement is reported to improve joint function and slow disease progression. Osteoarthritis is characterized...
FerumoxidesNot Annotated
Karaya gumAn extract from Karaya gum used in allergy testing.
TragacanthAn extract from Tragacanth used in allergy testing.
CarobAn extract from Carob used in allergy testing.
CarboxymethylcelluloseA compound used as an ophthalmic lubricant.
HypromelloseAn ingredient used in a wide variety of medications, and is not an approved medication.
PectinPectin is used in food as a gelling agent and stabilizer. As a medical drug, it has obtained a great interest in its potential use as a source of dietary...
MethylcelluloseA compound used as a bulk forming laxative and is not an approved medication.
PoliglusamPoliglusam, or chitosan, is a linear polysaccharide consisting of D-glucosamine and N-acetyl-D-glucosamine. Naturally-occuring poliglusam is found in the cell walls of fungi, soil and sediments where it is produced from...
Xanthan gumXanthan gum is a polysaccharide gum derived from* Xanthomonas campestris* by a pure-culture fermentation process and purified by recovery with isopropyl alcohol. The major constituents include D-glucose, D-mannose, and D-glucuronic...
AvilamycinNot Annotated
BambermycinsBambermycins are antibiotic complexes which are retrieved from the organism, Streptomyces bambergiensis. They are used as an additive in food ingested by chickens and swine. The bambermycin complex of antibiotics...
GleptoferronColloid solution of ferric hydroxide, dextran & glucoheptonic acid.
Tulathromycin ATulathromycin is a macrolide antibiotic used to treat bovine respiratory disease in cattle and swine respiratory disease in pigs. It is marketed by Pfizer Inc. under the tradename Draxxin.
Polysulfated glycosaminoglycanNot Annotated
Antithrombin III humanAn alpha-2-glycoprotein used to prevent thromboembolisms in patients with hereditary antithrombin III deficiency.
Starch, cornCorn starch refers to the starch extracted from the corn grain that is commonly used as a food ingredient and chemical additive. Starch is any of a group of polysaccharides...
Hydroxyethyl celluloseAn ingredient used in formulations to alleviate irritation of the skin.
Iron isomaltoside 1000Iron isomaltoside 1000 is under investigation in Iron Deficiency Anaemia. Iron isomaltoside 1000 has been investigated for the treatment and basic science of Anemia, Gastric Cancer, Esophageal Cancer, Chronic Kidney...
TrehaloseCabaletta has been used in trials studying the treatment of Oculopharyngeal Muscular Dystrophy.
SabarubicinSabarubicin has been used in trials studying the treatment of Prostate Cancer, Testicular Germ Cell Tumor, and Unspecified Adult Solid Tumor, Protocol Specific.
GaxiloseGaxilose has been used in trials studying the diagnostic of Lactose Intolerance.
SizofiranA beta-D-glucan obtained from the Aphyllophoral fungus Schizophyllum commune. It is used as an immunoadjuvant in the treatment of neoplasms, especially tumors found in the stomach. Sizofiran has been used...
Calcium glubionate anhydrousA calcium salt indicated in the treatment of hypocalcemia, hyperkalemia, lead poisoning, and as an adjunct in the treatment of exudative skin conditions.
Guar gumNot Annotated
LentinanNot Annotated
Alginic acidIndicated for the management of gastric reflux, reflux oesophagitis, hiatus hernia, heartburn (including heartburn of pregnancy) and similar gastric distress .
DextranomerNot Annotated
Oxidized celluloseNot Annotated
Meningococcal polysaccharide vaccine group AMeningococcal group A polysaccharide is group-specific polysaccharide antigens extracted and purified from Neisseria meningitidis serogroup A. N. meningitidis is a bacteria that causes endemic and epidemic diseases including meningitis and...
Meningococcal polysaccharide vaccine group CMeningococcal group C polysaccharide is group-specific polysaccharide antigens extracted and purified from Neisseria meningitidis serogroup C. N. meningitidis is a bacteria that causes endemic and epidemic diseases including meningitis and...
FondaparinuxAn anticoagulant used to prevent venous thromboembolism, to treat deep vein thrombosis, and to improve survival following myocardial infarction.
Hydroxyethyl ethylcelluloseHydroxyethyl ethylcellulose modulates bacterial binding to salivary pellicle; moderately effective in preventing plaque formation.
Microcrystalline celluloseA polysaccharide with glucose units linked as in CELLOBIOSE. It is the chief constituent of plant fibers, cotton being the purest natural form of the substance. As a raw material,...
BetadexNot Available
Dextrin 2-sulfateInvestigated for use/treatment in HIV prevention.
PolydextrosePolydextrose is under investigation in clinical trial NCT02258750 (Assessing a Polydextrose Containing Soup on Food Intake, Appetite and Biomarkers of Satiation and Satiety).
AmylopectinAmylopectin is under investigation in clinical trial NCT01708694 (Role of Slowly Digesible Starch on Diabetes Risk Factors).
Konjac mannanKonjac mannan is under investigation in clinical trial NCT01709955 (The Effects of Glucomannan on Weight Loss).
SucraloseSucralose is an artificial sweetener used as a sugar substitute.
AmyloseAmylose is under investigation in clinical trial NCT01027325 (Resistant Starch Insulin Sensitivity Trial).
Hydroxypropyl betadexHydroxypropyl betadex is under investigation in clinical trial NCT03471143 (Study of IV VTS-270 for Infantile Liver Disease Associated With Niemann-Pick Disease, Type C).
BrexanoloneBrexanolone is a synthetic neuroactive steroid gamma-aminobutyric acid A (GABA(a)) receptor positive modulator indicated for the treatment of postpartum depression (PPD) in adult women [FDA Label][A176080, A176083, F4063, F4066, F4072].
SevuparinSevuparin is under investigation in clinical trial NCT03853421 (Placebo-controlled Study to Determine the Safety and Tolerability of Subcutaneous Doses of Sevuparin).
4-methyl-umbelliferyl-N-acetyl-chitobioseNot Available
AcaciaAn extract from Acacia used in allergy testing.
Iron polymaltoseNot Annotated
Lactobacillus acidophilusNot Annotated
Dermatan sulfateA medication indicated to prevent deep vein thrombosis.
2'-Fucosyllactose2'-Fucosyllactose is under investigation in clinical trial NCT03847467 (Pilot and Feasibility Study of 2'-FL as a Dietary Supplement in IBD Patients Receiving Stable Maintenance Anti-tnf Therapy).
Mucopolysaccharide polysulphateAn anti-inflammatory and anticoagulant indicated in the treatment of bruising and varicose veins.
Lactobionic acidA component of a solution indicated in the preservation of organs from extraction to transplant.
Drugs & Drug Targets
DrugTargetType
Antihemophilic factor, human recombinantCoagulation factor Xtarget
Antihemophilic factor, human recombinantPhytanoyl-CoA dioxygenase, peroxisomaltarget
Antihemophilic factor, human recombinantCoagulation factor IXtarget
Antihemophilic factor, human recombinantAsialoglycoprotein receptor 2target
Antihemophilic factor, human recombinant78 kDa glucose-regulated proteintarget
Antihemophilic factor, human recombinantCalreticulintarget
Antihemophilic factor, human recombinantCalnexintarget
Antihemophilic factor, human recombinantProtein ERGIC-53target
Antihemophilic factor, human recombinantProlow-density lipoprotein receptor-related protein 1target
Antihemophilic factor, human recombinantMultiple coagulation factor deficiency protein 2target
Antihemophilic factor, human recombinantvon Willebrand factortarget
Antihemophilic factor, human recombinantProthrombinenzyme
Antihemophilic factor, human recombinantVitamin K-dependent protein Cenzyme
AcarboseMaltase-glucoamylase, intestinaltarget
AcarboseLysosomal alpha-glucosidasetarget
AcarboseSucrase-isomaltase, intestinaltarget
AcarbosePancreatic alpha-amylasetarget
ArdeparinHeparin cofactor 2target
ArdeparinAntithrombin-IIItarget
InulinCycloinulo-oligosaccharide fructanotransferasetarget
Pentosan polysulfateFibroblast growth factor 1target
Pentosan polysulfateFibroblast growth factor 4target
Pentosan polysulfateFibroblast growth factor 2target
IcodextrinPancreatic alpha-amylaseenzyme
IrinotecanDNA topoisomerase I, mitochondrialtarget
IrinotecanDNA topoisomerase 1target
IrinotecanCytochrome P450 3A4enzyme
IrinotecanCytochrome P450 3A5enzyme
IrinotecanUDP-glucuronosyltransferase 1-1enzyme
IrinotecanUDP-glucuronosyltransferase 1-9enzyme
IrinotecanLiver carboxylesterase 1enzyme
IrinotecanCytochrome P450 3A7enzyme
IrinotecanCytochrome P450 2B6enzyme
IrinotecanSolute carrier family 22 member 3transporter
IrinotecanSolute carrier organic anion transporter family member 1B1transporter
IrinotecanMultidrug resistance-associated protein 1transporter
IrinotecanATP-binding cassette sub-family G member 2transporter
IrinotecanSerum albumincarrier
IrinotecanCocaine esteraseenzyme
IrinotecanCholinesteraseenzyme
IrinotecanP-glycoprotein 1transporter
IrinotecanCanalicular multispecific organic anion transporter 1transporter
Iron DextranHemoglobin subunit betatarget
Iron DextranHemoglobin subunit alphatarget
Iron DextranFerritin heavy chaintarget
Iron DextranFerritin light chaintarget
Iron DextranSerotransferrincarrier
QuinidineSodium channel protein type 5 subunit alphatarget
QuinidineAlpha-1-acid glycoprotein 1carrier
QuinidinePotassium voltage-gated channel subfamily H member 2target
QuinidinePotassium channel subfamily K member 1target
QuinidinePotassium channel subfamily K member 6target
QuinidineCytochrome P450 1A2enzyme
QuinidineCytochrome P450 2E1enzyme
QuinidineCytochrome P450 1A1enzyme
QuinidineCytochrome P450 2D6enzyme
QuinidineCytochrome P450 3A4enzyme
QuinidineCytochrome P450 3A7enzyme
QuinidineSolute carrier family 22 member 2transporter
QuinidineSolute carrier family 22 member 1transporter
QuinidineSolute carrier family 22 member 5transporter
QuinidineP-glycoprotein 1transporter
QuinidineSolute carrier organic anion transporter family member 1A2transporter
QuinidineSolute carrier family 22 member 8transporter
QuinidineCanalicular multispecific organic anion transporter 1transporter
QuinidineSolute carrier family 22 member 4transporter
QuinidineSolute carrier organic anion transporter family member 1B1transporter
QuinidineCytochrome P450 2B6enzyme
QuinidineCytochrome P450 2C9enzyme
QuinidineAlpha-1A adrenergic receptortarget
QuinidineAlpha-1B adrenergic receptortarget
QuinidineAlpha-1D adrenergic receptortarget
QuinidineBile salt export pumptransporter
QuinidineCytochrome P450 2C8enzyme
QuinidineSerum albumincarrier
HeparinAntithrombin-IIItarget
HeparinCoagulation factor Xtarget
HeparinP-selectintarget
HeparinHeparanaseenzyme
HeparinFibroblast growth factor receptor 4target
HeparinFibroblast growth factor 4target
HeparinFibroblast growth factor 19target
HeparinFibroblast growth factor receptor 1target
HeparinFibroblast growth factor 1target
HeparinFibroblast growth factor receptor 2target
HeparinFibroblast growth factor 2target
HeparinPlatelet factor 4target
HeparinHepatocyte growth factortarget
HeparinThyroxine-binding globulincarrier
SucrosofateFibroblast growth factor 1target
SucrosofateFibroblast growth factor receptor 2target
CellobioseEndoglucanase Gtarget
CellobioseEndoglucanase 5Atarget
CellobioseEndoglucanasetarget
MaltotetraoseGlucan 1,4-alpha-maltotetraohydrolasetarget
MaltotetraoseNeopullulanase 2target
Trehalose-6-PhosphateHTH-type transcriptional regulator TreRtarget
CellotetraoseCellulose 1,4-beta-cellobiosidasetarget
beta-D-galactopyranosyl-(1->4)-beta-D-galactopyranoseArabinogalactan endo-1,4-beta-galactosidasetarget
SucroseBeta-lactamasetarget
SucroseLysozyme Ctarget
SucroseActin, alpha skeletal muscletarget
SucroseBeta-glucosidasetarget
SucroseAmylosucrasetarget
SucroseBeta-lactamasetarget
SucroseBeta-lactamase CTX-Mtarget
SucroseHeme oxygenasetarget
SucroseCopper transport protein ATOX1target
SucrosetRNA-splicing ligase RtcB homologtarget
SucroseOrange carotenoid-binding proteintarget
SucroseSucrose porintarget
SucroseLevansucrasetarget
SucroseTaste receptor type 1 member 2target
MaltoseCyclomaltodextrin glucanotransferasetarget
MaltoseAlpha-amylase 2Btarget
MaltoseBeta-amylasetarget
MaltoseMaltogenic alpha-amylasetarget
MaltoseMaltodextrin phosphorylasetarget
MaltoseMaltose-binding periplasmic proteintarget
MaltoseAlpha-glucosidasetarget
MaltoseMaltose binding proteintarget
MaltoseMalto-oligosyltrehalose trehalohydrolasetarget
AllolactoseBeta-galactosidasetarget
LactoseBeta-galactosidasetarget
LactoseGlycosyltransferase 6 domain-containing protein 1target
LactoseGlycolipid transfer proteintarget
LactoseHydrolasetarget
LactoseEndo-1,4-beta-xylanase Atarget
LactoseGalectin-3target
LactoseSialidasetarget
LactoseBeta-galactosidasetarget
AllosamidinChitinase Btarget
AllosamidinChitinase Atarget
EritoranToll-like receptor 4target
Pentaerythritol tetranitrateHemoglobin subunit alphatarget
Pentaerythritol tetranitrateHemoglobin subunit betatarget
Pentaerythritol tetranitrateGuanylate cyclase soluble subunit alpha-2enzyme
Pentaerythritol tetranitrateFree radicalstarget
Pentaerythritol tetranitrateNitric oxide synthase, endothelialenzyme
Pentaerythritol tetranitrateAldehyde dehydrogenase, mitochondrialenzyme
SulodexideHeparin cofactor 2target
SulodexideAntithrombin-IIItarget
IdraparinuxCoagulation factor Xtarget
E5531Toll-like receptor 4target
DanaparoidAntithrombin-IIItarget
Sodium cellulose phosphateCalcium ionstarget
DalteparinVascular endothelial growth factor Atarget
DalteparinTissue factor pathway inhibitortarget
DalteparinHeparanaseenzyme
DalteparinAntithrombin-IIItarget
DalteparinP-selectintarget
TinzaparinAntithrombin-IIItarget
TinzaparinA disintegrin and metalloproteinase with thrombospondin motifs 4enzyme
TinzaparinIntegrin alpha-4target
TinzaparinStromal cell-derived factor 1target
NadroparinProto-oncogene c-Fostarget
NadroparinMyc proto-oncogene proteintarget
NadroparinP-selectintarget
NadroparinAntithrombin-IIItarget
Hyaluronic acidCD44 antigentarget
Hyaluronic acidIntercellular adhesion molecule 1target
Hyaluronic acidHyaluronan mediated motility receptortarget
Hyaluronic acidNeurocan core proteintarget
Hyaluronic acidVersican core proteintarget
Hyaluronic acidComplement component 1 Q subcomponent-binding protein, mitochondrialtarget
Hyaluronic acidHyaluronan and proteoglycan link protein 1target
Hyaluronic acidHyaluronan and proteoglycan link protein 3target
Hyaluronic acidHyaluronan-binding protein 2target
Hyaluronic acidLayilintarget
Hyaluronic acidStabilin-2target
Hyaluronic acidTumor necrosis factor-inducible gene 6 proteintarget
Hyaluronic acidInterphotoreceptor matrix proteoglycan 2target
Hyaluronic acidIntracellular hyaluronan-binding protein 4target
Hyaluronic acidHyaluronidase enzymesenzyme
Hyaluronic acidMultidrug resistance-associated protein 5transporter
Hyaluronic acidLymphatic vessel endothelial hyaluronic acid receptor 1target
BemiparinCoagulation factor Xtarget
BemiparinAntithrombin-IIItarget
BemiparinHeparin cofactor 2target
Chondroitin sulfateBrain-derived neurotrophic factortarget
Chondroitin sulfateGlial cell line-derived neurotrophic factortarget
Chondroitin sulfateVascular endothelial growth factor Atarget
Chondroitin sulfateC-C motif chemokine 2target
Chondroitin sulfateBeta-glucuronidaseenzyme
Chondroitin sulfateBeta-hexosaminidase subunit betaenzyme
Chondroitin sulfateN-acetylgalactosamine-6-sulfataseenzyme
Chondroitin sulfateIduronate 2-sulfataseenzyme
Chondroitin sulfateAlpha-L-iduronidaseenzyme
Chondroitin sulfateArylsulfatase Benzyme
CarboxymethylcelluloseSolute carrier family 2, facilitated glucose transporter member 1target
HypromelloseEpithelial cell adhesion moleculetarget
Antithrombin III humanAntithrombin-IIItarget
FondaparinuxAntithrombin-IIItarget
FondaparinuxCoagulation factor Xtarget
BetadexNeopullulanase 2target
BetadexMaltose-binding periplasmic proteintarget
BetadexMaltogenic amylasetarget
BrexanoloneGABA(A) Receptortarget
BrexanoloneAldose reductaseenzyme
4-methyl-umbelliferyl-N-acetyl-chitobioseLysozyme Ctarget