Mitomycins
- Name
- Mitomycins
- Accession Number
- DBCAT000710
- Description
A group of methylazirinopyrroloindolediones obtained from certain Streptomyces strains. They are very toxic antibiotics used as ANTINEOPLASTIC AGENTS in some solid tumors. PORFIROMYCIN and MITOMYCIN are the most useful members of the group.
- Drugs
Drug Drug Description Mitomycin An antimetabolite used as an adjunct to ab externo (outside approach) eye surgeries for the treatment of glaucoma and used as a chemotherapeutic agent for various malignancies. Porfiromycin Investigated for use/treatment in head and neck cancer. - Drugs & Drug Targets
Drug Target Type Mitomycin DNA target Mitomycin NADPH--cytochrome P450 reductase enzyme Porfiromycin Xanthine dehydrogenase/oxidase enzyme