Porfiromycin

DB06478InvestigationalSmall molecule

Porfiromycin is a substance that is being studied in the treatment of cancer. It belongs to the family of drugs called anticancer antibiotics.

Mechanism: Pharmacologically active on NAD(P)H dehydrogenase [quinone] 1
Curator reviewed
Primary indication: Investigated for use/treatment in head and neck cancer.Curator reviewed
Formula / weight: C₁₆H₂₀N₄O₅ · 348.359 g/mol (avg)
Code names: NSC-56410 · U-14,743

Resolves to

Compound

Structure

InChIKeyHRHKSTOGXBBQCB-VFWICMBZSA-NSMILESCO[C@]12[C@@H]3[C@H](CN1C1=C([C@H]2COC(N)=O)C(=O)C(N)=C(C)C1=O)N3C

Targets

What you can answer from here — as of July 17, 2026

1Protein targetEach mapped to UniProt, with action and pharmacological action

Listed above

39Drug interactionsStructured to mechanism, not free text

4Clinical trialsPhase, status and sponsor resolved per trial

6+ReferencesStructured and connected to the statements they support

Which drugs share a target with Porfiromycin, and which of those have an active Phase 3 trial?

Create a free account or log in to explore the full data card.