Antimanic Agents

Name
Antimanic Agents
Accession Number
DBCAT000733
Description

Agents that are used to treat bipolar disorders or mania associated with other affective disorders.

Drugs
DrugDrug Description
Lithium cationA drug used for the management of bipolar disorder and other psychiatric conditions.
Valproic acidAn anticonvulsant used to control complex partial seizures and both simple and complex absence seizures.
CarbamazepineAn anticonvulsant used to treat various types of seizures and pain resulting from trigeminal neuralgia.
Lithium carbonateA medication used to treat manic episodes of bipolar disorder.
Lithium citrateLithium is used as a mood stabilizer, and is used for treatment of depression and mania. It is often used in bipolar disorder treatment.
Lithium chlorideAn injection indicated for cardiac output measurement.
Drugs & Drug Targets
DrugTargetType
Lithium cationInositol monophosphatase 2target
Lithium cationInositol monophosphatase 1target
Lithium cationGlycogen synthase kinase-3 betatarget
Lithium cationGlutamate receptor 3target
Valproic acidHistone deacetylase 9target
Valproic acidShort/branched chain specific acyl-CoA dehydrogenase, mitochondrialtarget
Valproic acidCytochrome P450 2A6enzyme
Valproic acidCytochrome P450 2B6enzyme
Valproic acidCytochrome P450 2C9enzyme
Valproic acidSolute carrier family 22 member 5transporter
Valproic acidSolute carrier family 22 member 6transporter
Valproic acidSolute carrier family 22 member 8transporter
Valproic acidMonocarboxylate transporter 1transporter
Valproic acidSolute carrier family 22 member 7transporter
Valproic acidCytochrome P450 3A5enzyme
Valproic acidUDP-glucuronosyltransferase 1-9enzyme
Valproic acidProstaglandin G/H synthase 1enzyme
Valproic acidCytochrome P450 1A2enzyme
Valproic acidCytochrome P450 2C19enzyme
Valproic acidCytochrome P450 3A4enzyme
Valproic acidUDP-glucuronosyltransferase 1-4enzyme
Valproic acidUDP-glucuronosyltransferase 1-8enzyme
Valproic acidUDP-glucuronosyltransferase 1-10enzyme
Valproic acidUDP-glucuronosyltransferase 1-6enzyme
Valproic acidUDP-glucuronosyltransferase 1-3enzyme
Valproic acidUDP-glucuronosyltransferase 2B7enzyme
Valproic acidUDP-glucuronosyltransferase 2B15enzyme
Valproic acid2-oxoglutarate dehydrogenase, mitochondrialtarget
Valproic acidSuccinate-semialdehyde dehydrogenase, mitochondrialtarget
Valproic acidSodium channel proteintarget
Valproic acidHistone deacetylase 2target
Valproic acidPeroxisome proliferator-activated receptor alphatarget
Valproic acidPeroxisome proliferator-activated receptor deltatarget
Valproic acidPeroxisome proliferator-activated receptor gammatarget
Valproic acidSerum albumincarrier
Valproic acidUDP-glucuronosyltransferase 1-1enzyme
Valproic acidSolute carrier organic anion transporter family member 2B1transporter
CarbamazepineVoltage-gated sodium channel alpha subunittarget
CarbamazepineCytochrome P450 2C8enzyme
CarbamazepineCytochrome P450 2B6enzyme
CarbamazepineCytochrome P450 3A4enzyme
CarbamazepineCytochrome P450 1A2enzyme
CarbamazepineCytochrome P450 2C19enzyme
CarbamazepineCytochrome P450 2C9enzyme
CarbamazepineP-glycoprotein 1transporter
CarbamazepineCytochrome P450 3A5enzyme
CarbamazepineUDP-glucuronosyltransferase 2B7enzyme
CarbamazepineRalA-binding protein 1transporter
CarbamazepineCanalicular multispecific organic anion transporter 1transporter
CarbamazepineNeuronal acetylcholine receptor subunit alpha-4target
CarbamazepineNuclear receptor subfamily 1 group I member 2target
CarbamazepineUDP-glucuronosyltransferase 1-1enzyme
CarbamazepineUDP-glucuronosyltransferase 1-6enzyme
CarbamazepineUDP-glucuronosyltransferase 1-7enzyme
Lithium carbonateInositol monophosphatase 2target
Lithium carbonateInositol monophosphatase 1target
Lithium carbonateGlycogen synthase kinase-3 betatarget
Lithium carbonateGlutamate receptor 3target
Lithium carbonateAmiloride-sensitive sodium channel subunit alphatransporter
Lithium carbonateAmiloride-sensitive sodium channel subunit betatransporter
Lithium carbonateAmiloride-sensitive sodium channel subunit gammatransporter
Lithium citrateInositol monophosphatase 2target
Lithium citrateInositol monophosphatase 1target
Lithium citrateGlycogen synthase kinase-3 betatarget
Lithium citrateGlutamate receptor 3target