Thienamycins

Name: Thienamycins
Accession Number: DBCAT001394
Description: Beta-lactam antibiotics that differ from PENICILLINS in having the thiazolidine sulfur atom replaced by carbon, the sulfur then becoming the first atom in the side chain. They are unstable chemically, but have a very broad antibacterial spectrum. Thienamycin and its more stable derivatives are proposed for use in combinations with enzyme inhibitors.
Drugs: Drug Drug Description
Imipenem A carbapenem antibiotic normally administered with cilastatin to treat a variety of infections.
Meropenem A carbapenem antibiotic used to treat a wide variety of infections in the body.
Drugs & Drug Targets: Drug Target Type
Imipenem Penicillin-binding protein 1A target
Imipenem Penicillin-binding protein 1B target
Imipenem Peptidoglycan D,D-transpeptidase MrdA target
Imipenem Penicillin-binding protein 3 target
Imipenem Dipeptidase 1 enzyme
Imipenem Penicillin-binding protein 4 target
Imipenem Beta-lactamase SHV-1 enzyme
Imipenem Beta-lactamase TEM enzyme
Imipenem Beta-lactamase CTX-M enzyme
Imipenem Beta-lactamase enzyme
Imipenem Beta-lactamase target
Imipenem Penicillin-binding protein target
Meropenem D-alanyl-D-alanine carboxypeptidase DacB target
Meropenem Beta-lactamase OXA-10 enzyme
Meropenem Dipeptidase 1 enzyme
Meropenem Penicillin-binding protein target

Drug	Drug Description
Imipenem	A carbapenem antibiotic normally administered with cilastatin to treat a variety of infections.
Meropenem	A carbapenem antibiotic used to treat a wide variety of infections in the body.