Tachykinins
- Name
- Tachykinins
- Accession Number
- DBCAT001751
- Description
A family of biologically active peptides sharing a common conserved C-terminal sequence, -Phe-X-Gly-Leu-Met-NH2, where X is either an aromatic or a branched aliphatic amino acid. Members of this family have been found in mammals, amphibians, and mollusks. Tachykinins have diverse pharmacological actions in the central nervous system and the cardiovascular, genitourinary, respiratory, and gastrointestinal systems, as well as in glandular tissues. This diversity of activity is due to the existence of three or more subtypes of tachykinin receptors.
- Drugs
Drug Drug Description Sar9, Met (O2)11-Substance P Investigated for use/treatment in acute respiratory distress syndrome (ARDS) and viral infection. - Drugs & Drug Targets
Drug Target Type Sar9, Met (O2)11-Substance P Cytochrome P450 19A1 enzyme Sar9, Met (O2)11-Substance P Cholinesterase enzyme Sar9, Met (O2)11-Substance P Prostaglandin G/H synthase 2 enzyme