Tumor Necrosis Factor Decoy Receptors
- Name
- Tumor Necrosis Factor Decoy Receptors
- Accession Number
- DBCAT001811
- Description
A subclass of tumor necrosis family receptors that lack cell signaling domains. They bind to specific TNF RECEPTOR LIGANDS and are believed to play a modulating role in the TNF signaling pathway. Some of the decoy receptors are products of distinct genes, while others are products of ALTERNATIVE SPLICING of the MRNA for the active receptor.
- Drugs
Drug Drug Description AMGN-0007 Investigated for use/treatment in osteoporosis and bone metastases. - Drugs & Drug Targets
Drug Target Type AMGN-0007 Tumor necrosis factor ligand superfamily member 11 target