Tumor Necrosis Factor Decoy Receptors

Name
Tumor Necrosis Factor Decoy Receptors
Accession Number
DBCAT001811
Description

A subclass of tumor necrosis family receptors that lack cell signaling domains. They bind to specific TNF RECEPTOR LIGANDS and are believed to play a modulating role in the TNF signaling pathway. Some of the decoy receptors are products of distinct genes, while others are products of ALTERNATIVE SPLICING of the MRNA for the active receptor.

Drugs
DrugDrug Description
AMGN-0007Investigated for use/treatment in osteoporosis and bone metastases.
Drugs & Drug Targets
DrugTargetType
AMGN-0007Tumor necrosis factor ligand superfamily member 11target