Drugs Used in Hereditary Angioedema

Name
Drugs Used in Hereditary Angioedema
Accession Number
DBCAT002563
Description

Not Available

ATC Classification
Drugs
DrugDrug Description
EcallantideA kallikrein inhibitor used to prevent and treat acute attacks caused by Hereditary Angioedema (HAE).
IcatibantA bradykinin B2 receptor antagonist used to treat acute episodes of swelling and inflammation associated with hereditary angioedema (HAE).
Human C1-esterase inhibitorA C1 inhibitor used to prevent angioedema attacks associated with hereditary angioedema.
Conestat alfaA recombinant C1INH used for the treatment of acute attacks of hereditary angioedema (HAE) due to C1 esterase inhibitor deficiency in adults.
LanadelumabA plasma kallikrein inhibitor used to treat attacks of hereditary angioedema.
BerotralstatAn inhibitor of plasma kallikrein used for prophylaxis of angioedema attacks in patients with hereditary angioedema.
Drugs & Drug Targets
DrugTargetType
EcallantidePlasma kallikreintarget
IcatibantB2 bradykinin receptortarget
IcatibantAminopeptidase Ntarget
Human C1-esterase inhibitorComplement C1r subcomponenttarget
Human C1-esterase inhibitorComplement C1s subcomponenttarget
Human C1-esterase inhibitorPlasma kallikreintarget
Human C1-esterase inhibitorCoagulation factor XIItarget
Human C1-esterase inhibitorProthrombintarget
Human C1-esterase inhibitorCoagulation factor XItarget
Human C1-esterase inhibitorTissue-type plasminogen activatortarget
Conestat alfaComplement C1r subcomponenttarget
Conestat alfaComplement C1s subcomponenttarget
Conestat alfaPlasma kallikreintarget
Conestat alfaCoagulation factor XIItarget
Conestat alfaProthrombintarget
Conestat alfaCoagulation factor XItarget
Conestat alfaTissue-type plasminogen activatortarget
LanadelumabPlasma kallikreintarget
BerotralstatCytochrome P450 2D6enzyme
BerotralstatCytochrome P450 3A4enzyme
BerotralstatP-glycoprotein 1transporter
BerotralstatATP-binding cassette sub-family G member 2transporter
BerotralstatPlasma kallikreintarget