Taxane Derivatives

All categories

Name: Taxane Derivatives
Accession Number: DBCAT002720
Description: Not Available
Drugs: Drug Drug Description
Cabazitaxel An antineoplastic agent used in combination with corticosteroids to treat metastatic castration-resistant prostate cancer in patients previously treated with a docetaxel-containing treatment regimen.
Docetaxel A taxoid antineoplastic agent used in the treatment of various cancers, such as locally advanced or metastatic breast cancer, metastatic prostate cancer, gastric adenocarcinoma, and head and neck cancer.
Paclitaxel A taxoid chemotherapeutic agent used as first-line and subsequent therapy for the treatment of advanced carcinoma of the ovary, and other various cancers including breast and lung cancer.
Drugs & Drug Targets: Drug Target Type
Cabazitaxel Glycosylphosphatidylinositol-anchored high density lipoprotein-binding protein 1 carrier
Cabazitaxel Very low-density lipoprotein receptor carrier
Cabazitaxel Low-density lipoprotein receptor carrier
Cabazitaxel Albumin carrier
Cabazitaxel Solute carrier organic anion transporter family member 1B3 transporter
Cabazitaxel Solute carrier organic anion transporter family member 1B1 transporter
Cabazitaxel Tubulin beta-1 chain target
Cabazitaxel Broad substrate specificity ATP-binding cassette transporter ABCG2 transporter
Cabazitaxel ATP-dependent translocase ABCB1 transporter
Cabazitaxel Cytochrome P450 2C8 enzyme
Cabazitaxel Cytochrome P450 3A5 enzyme
Cabazitaxel Cytochrome P450 3A4 enzyme
Docetaxel ATP-dependent translocase ABCB1 transporter
Docetaxel Apoptosis regulator Bcl-2 target
Docetaxel Tubulin beta-1 chain target
Docetaxel Cytochrome P450 3A4 enzyme
Docetaxel Cytochrome P450 3A5 enzyme
Docetaxel Cytochrome P450 3A7 enzyme
Docetaxel ATP-binding cassette sub-family C member 10 transporter
Docetaxel Cytochrome P450 1B1 enzyme
Docetaxel Solute carrier organic anion transporter family member 1B3 transporter
Docetaxel Solute carrier family 22 member 7 transporter
Docetaxel Broad substrate specificity ATP-binding cassette transporter ABCG2 transporter
Docetaxel ATP-binding cassette sub-family C member 2 transporter
Docetaxel Multidrug resistance-associated protein 1 transporter
Docetaxel Nuclear receptor subfamily 1 group I member 2 target
Paclitaxel Nuclear receptor subfamily 1 group I member 2 target
Paclitaxel ATP-binding cassette sub-family C member 2 transporter
Paclitaxel Solute carrier organic anion transporter family member 1B3 transporter
Paclitaxel Cytochrome P450 1B1 enzyme
Paclitaxel Aromatase enzyme
Paclitaxel ATP-binding cassette sub-family C member 10 transporter
Paclitaxel Multidrug resistance-associated protein 1 transporter
Paclitaxel ATP-dependent translocase ABCB1 transporter
Paclitaxel Bile salt export pump transporter
Paclitaxel Cytochrome P450 3A7 enzyme
Paclitaxel Cytochrome P450 3A5 enzyme
Paclitaxel Cytochrome P450 3A4 enzyme
Paclitaxel Cytochrome P450 2C8 enzyme
Paclitaxel Tubulin beta-1 chain target
Paclitaxel Apoptosis regulator Bcl-2 target

Drug	Drug Description
Cabazitaxel	An antineoplastic agent used in combination with corticosteroids to treat metastatic castration-resistant prostate cancer in patients previously treated with a docetaxel-containing treatment regimen.
Docetaxel	A taxoid antineoplastic agent used in the treatment of various cancers, such as locally advanced or metastatic breast cancer, metastatic prostate cancer, gastric adenocarcinoma, and head and neck cancer.
Paclitaxel	A taxoid chemotherapeutic agent used as first-line and subsequent therapy for the treatment of advanced carcinoma of the ovary, and other various cancers including breast and lung cancer.

Taxane Derivatives

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