Antineoplastic Agents

Name
Antineoplastic Agents
Accession Number
DBCAT000024
Description

Substances that inhibit or prevent the proliferation of NEOPLASMS.

ATC Classification
Drugs
DrugDrug Description
CetuximabAn endothelial growth factor receptor binding fragment used to treat colorectal cancer as well as squamous cell carcinoma of the head and neck.
Denileukin diftitoxA recombinant cytotoxic protein based on a combination of diphtheria toxin fragments and interleukin-2 used to treat cutaneous T-cell lymphoma by targeting the interleukin-2 receptor.
Asparaginase Escherichia coliAn asparaginase enzyme from E. coli used as part of treatment regimens for acute lymphoblastic leukemias.
PegaspargaseA modified form of L-asparagine amidohydrolase used to treat acute lymphoblastic leukemia, which is dependent on an external source of asparagine.
TrastuzumabA monoclonal anti-human epidermal growth factor receptor 2 protein antibody used to treat HER2-positive breast, gastroesophageal, and gastric cancers.
RituximabA monoclonal anti-CD20 antibody used to treat non-Hodgkin's lymphoma, chronic lymphocytic leukemia, Wegener's granulomatosis, pemphigus vulgaris, and rheumatoid arthritis.
BevacizumabA monoclonal anti-vascular endothelial growth factor antibody used in combination with antineoplastic agents for the treatment of many types of cancer.
BortezomibA proteasome inhibitor used to treat multiple myeloma in patients who have not been successfully treated with at least two previous therapies.
PipobromanFor the treatment of polycythaemia vera and refractory chronic myeloid leukaemia.
CladribineA purine antimetabolite used for the management of relapsing forms of Multiple Sclerosis (MS), used in patients who have not responded to or who were unable to tolerate alternative MS drugs.
CarmustineAn alkylating agent used in the treatment of various malignancies, including brain tumours and multiple myeloma, among others.
AmsacrineA cytotoxic agent used to induce remission in acute adult leukemia that is not adequately responsive to other agents.
BleomycinA chemotherapy agent used to treat various malignancies, including head and neck malignancy, lymphoma, and testicular tumors, among others.
ChlorambucilA chemotherapy agent used in the management of chronic lymphocytic leukemia and malignant lymphomas.
RaltitrexedA folate analog thymidylate synthase inhibitor used in the treatment of advanced colorectal cancer.
MitomycinAn antimetabolite used as an adjunct to ab externo (outside approach) eye surgeries for the treatment of glaucoma and used as a chemotherapeutic agent for various malignancies.
BexaroteneA retinoid drug used for cutaneous manifestations of T-cell lymphoma in patients who have not responded well to previous systemic therapy.
VindesineA vinca alkaloid derived from vinblastine used for various types of malignancies, but mainly acute lymphocytic leukemia (ALL).
GefitinibA tyrosine kinase inhibitor used as first-line therapy to treat non-small cell lung carcinoma (NSCLC) that meets certain genetic mutation criteria.
TioguanineA purine analogue antineoplastic agent used for the induction of remission, and for remission consolidation in patients with acute nonlymphocytic anemias.
VinorelbineA vinca alkaloid used in the treatment of metastatic non-small cell lung carcinoma (NSLC) and in conjunction with other drugs in locally advanced NSCLC.
ValrubicinAn anthracycline used intravesically in the treatment of BCG-resistant bladder carcinoma.
SorafenibA kinase inhibitor used in the treatment of unresectable liver carcinoma and advanced renal carcinoma.
StreptozocinA nitrosourea antineoplastic agent used in the treatment of metastatic pancreatic islet cell carcinoma.
GemcitabineA nucleoside metabolic inhibitor used as adjunct therapy in the treatment of certain types of ovarian cancer, non-small cell lung carcinoma, metastatic breast cancer, and as a single agent for pancreatic cancer.
TeniposideA cytotoxic drug used as an adjunct for chemotherapy induction in the treatment of refractory childhood acute lymphoblastic leukemia.
EpirubicinAn anthracycline topoisomerase II inhibitor used as an adjuvant to treating axillary node metastases in patients who have undergone surgical resection of primary breast cancer.
AltretamineAn antineoplastic agent used in palliative treatment of persistent or recurrent ovarian cancer.
CisplatinA platinum based chemotherapy agent used to treat various sarcomas, carcinomas, lymphomas, and germ cell tumors.
AlitretinoinA vitamin A derivative used to treat Kaposi's sarcoma and used off label to treat chronic hand eczema and psoriasis.
OxaliplatinA platinum based chemotherapy agent used to treat carcinoma of the colon or rectum or stage III colon cancer.
ErlotinibAn EGFR tyrosine kinase inhibitor used to treat certain small cell lung cancers or advanced metastatic pancreatic cancers.
CyclophosphamideA nitrogen mustard used to treat lymphomas, myelomas, leukemia, mycosis fungoides, neuroblastoma, ovarian adenocarcinoma, retinoblastoma, and breast carcinoma.
VincristineA vinca alkaloid used to treat acute leukemia, malignant lymphoma, Hodgkin's disease, acute erythraemia, and acute panmyelosis.
FluorouracilA pyrimidine analog used to treat basal cell carcinomas, and as an injection in palliative cancer treatment.
PentostatinAn adenosine deaminase inhibitor used to treat hairy cell leukemia.
MethotrexateAn antineoplastic agent used the treatment of a wide variety of cancers as well as severe psoriasis, severe rheumatoid arthritis, and juvenile rheumatoid arthritis.
VinblastineA vinca alkaloid used to treat breast cancer, testicular cancer, neuroblastoma, Hodgkin's and non-Hodgkins lymphoma, mycosis fungoides, histiocytosis, and Kaposi's sarcoma.
ImatinibA tyrosine kinase inhibitor used to treat a number of leukemias, myelodysplastic/myeloproliferative disease, systemic mastocytosis, hypereosinophilic syndrome, dermatofibrosarcoma protuberans, and gastrointestinal stromal tumors.
ClofarabineA purine nucleoside used to treat relapsed or refractory acute lymphoblastic leukemia in patients 1 to 21 years old.
PemetrexedA folate analog used to treat mesothelioma and non-small cell lung cancer.
MitotaneAn adrenal cortex inhibitor used to treat adrenocortical tumors and Cushing's syndrome.
DaunorubicinAn anthracycline aminoglycoside used to induce remission of nonlymphocytic leukemia and acute lymphocytic leukemia.
Porfimer sodiumA hematoporphyrin derivative used to treat esophageal cancer, endobronchial cancer, and high grade dysplasia in Barrett's Esophagus.
IrinotecanAn antineoplastic enzyme inhibitor used to treat metastatic carcinoma of the colon or rectum.
EtoposideA podophyllotoxin derivative used to treat testicular and small cell lung tumors.
DacarbazineAn antineoplastic agent used to treat malignant melanoma and Hodgkin's disease.
TemozolomideAn alkylating agent used to treat glioblastoma multiforme and refractory anaplastic astrocytoma.
MechlorethamineAn antineoplastic agent used to treat Hodgkin's disease, lymphosarcoma, and chronic myelocytic or lymphocytic leukemia.
AzacitidineA pyrimidine nucleoside analogue used to treat certain subtypes of myelodysplastic syndrome.
CarboplatinA alkylating agent used to treat advanced ovarian cancer.
DactinomycinAn actinomycin used to treat a wide variety of cancers.
CytarabineA pyrimidine nucleoside analogue used to treat acute non-lymphocytic leukemia, lymphocytic leukemia, and the blast phase of chronic myelocytic leukemia.
DoxorubicinA medication used to treat various cancers and Kaposi's Sarcoma.
HydroxyureaAn antimetabolite used to treat sickle cell anemia crisis.
BusulfanAn alkylating agent used to treat chronic myelogenous leukemia.
TopotecanAn antineoplastic agent used to treat ovarian cancer, small cell lung cancer, or cervical cancer.
MercaptopurineAn antineoplastic agent used to treat acute lymphocytic leukemia.
MelphalanAn alkylating antineoplastic agent used to treat multiple myeloma and ovarian carcinoma.
FludarabineA purine analog antimetabolite that inhibits DNA synthesis.
CapecitabineA nucleoside metabolic inhibitor indicated to treat colon, colorectal and breast cancer.
ProcarbazineAn antineoplastic agent indicated for the treatment of stage III and stage IV Hodgkin's disease in combination with other chemotherapeutic agents.
Arsenic trioxideA chemotherapeutic agent used in the treatment of refractory or relapsed acute promyelocytic leukemia in patients with prior retinoid and anthracycline chemotherapy.
IdarubicinAn anthracycline antineoplastic agent used to treat acute myeloid leukemia (AML) in adults.
IfosfamideAn alkylating and immunosuppressive agent used in chemotherapy for the treatment of cancers, including testicular cancer, ovarian cancer, cervical cancer, osteocarcinoma, bladder cancer, small cell lung cancer, and non-Hodgkin's lymphoma.
EstramustineAn antineoplastic agent used for the management of metastatic and/or progressive prostate cancer in palliative setting.
MitoxantroneA chemotherapeutic agent used for the treatment of secondary progressive, progressive relapsing, or worsening relapsing-remitting multiple sclerosis.
LomustineAn alkylating agent used as a part of chemotherapeutic regimens for the treatment of primary and metastatic brain tumors as well as refractory or relapsed Hodgkin's disease in addition to surgical and/or radiotherapeutic treatments.
PaclitaxelA taxoid chemotherapeutic agent used as first-line and subsequent therapy for the treatment of advanced carcinoma of the ovary, and other various cancers including breast and lung cancer.
DocetaxelA taxoid antineoplastic agent used in the treatment of various cancers, such as locally advanced or metastatic breast cancer, metastatic prostate cancer, gastric adenocarcinoma, and head and neck cancer.
DasatinibA tyrosine kinase inhibitor used for the treatment of lymphoblastic or chronic myeloid leukemia with resistance or intolerance to prior therapy.
LapatinibAn antineoplastic agent and tyrosine kinase inhibitor used for the treatment of advanced or metastatic HER-negative breast cancer in patients who received prior chemotherapeutic treatments.
DecitabineA chemotherapeutic pyrimidine nucleoside analogue used for the treatment of myelodysplastic syndromes (MDS) by inducing DNA hypomethylation and corresponding alterations in gene expression.
SunitinibA receptor tyrosine kinase inhibitor and chemotherapeutic agent used for the treatment of renal cell carcinoma (RCC) and imatinib-resistant gastrointestinal stromal tumor (GIST).
PanitumumabA recombinant humanized monoclonal antibody used to treat EGFR-expressing, metastatic colorectal carcinoma that is refractory to fluoropyrimidine-, oxaliplatin-, and irinotecan- containing chemotherapy regimens.
VorinostatA histone deacetylase (HDAC) inhibitor used for the treatment of cutaneous manifestations in patients with progressive, persistent, or recurrent cutaneous T- cell lymphoma (CTCL) following prior systemic therapies.
FotemustineNot Available
ThiotepaAn alkylating agent used to prevent graft rejection in stem cell transplantation and to treat a variety of malignancies including certain types of adenocarcinoma and superficial bladder carcinomas.
Omacetaxine mepesuccinateA cephalotaxine used in the treatment of Chronic Myeloid Leukemia (CML) that is intolerant to or resistant to two or more tyrosine kinase inhibitors.
SatraplatinInvestigated for use/treatment in lung cancer, prostate cancer, and solid tumors.
BelinostatA histone deacetylase (HDAC) inhibitor used for the treatment of patients with relapsed or refractory peripheral T-cell lymphoma (PTCL).
TrabectedinAn alkylating agent approved for the treatment of unresectable or metastatic soft tissue sarcoma (liposarcoma or leiomyosarcoma).
RamucirumabAn antineoplastic agent and direct VEGFR2 (vascular endothelial growth factor receptor 2) antagonist that blocks the binding of natural VEGF ligands, which are secreted by solid tumors to promote angiogenesis and enhance tumor blood supply.
Trastuzumab emtansineAn antineoplastic agent and antibody-drug conjugate used to treat HER2-overexpressing breast cancer.
RomidepsinA histone deacetylase (HDAC) inhibitor used to treat cutaneous and peripheral T-cell lymphoma.
PixantroneAn antineoplastic agent use to treat patients with relapsed or refractory aggressive Non-Hodgkin B-cell Lymphomas (NHL).
AmrubicinInvestigated for use/treatment in lung cancer .
LonidamineInvestigated for use/treatment in benign prostatic hyperplasia, prostate disorders, and cancer/tumors (unspecified).
TemsirolimusA antineoplastic agent used in the treatment of renal cell carcinoma (RCC) that works by inhibiting mTOR.
PertuzumabAn antineoplastic agent used in the treatment of HER2-positive metastatic breast cancer in combination with other antineoplastic agents.
PanobinostatA non-selective histone deacetylase inhibitor used to treat multiple myeloma in combination with other antineoplastic agents.
BendamustineAn antineoplastic agent used for the treatment of chronic lymphocytic leukemia (CLL) and indolent B-cell non-Hodgkin lymphoma (NHL) that has progressed following rituximab therapy.
PlicamycinFor the treatment of testicular cancer, as well as hypercalcemia and hypercalciuria associated with a variety of advanced forms of cancer.
PonatinibA kinase inhibitor used to treat patients with various types of chronic myeloid leukemia (CML).
TrametinibA kinase inhibitor used to treat patients with specific types of melanoma, non-small cell lung cancer, and thyroid cancer.
DabrafenibA kinase inhibitor used to treat patients with specific types of melanoma, non-small cell lung cancer, and thyroid cancer.
ObinutuzumabAn antineoplastic CD20 antibody used to treat untreated chronic lymphocytic leukemia in combination with chlorambucil.
CarmofurCarmofur is a derivative of fluorouracil, and is an antineoplastic agent that has been used in the treatment of breast and colorectal cancer. Carmofur has been known to induce leukoencephalopathy.
MiltefosineAn antileishmanial agent used to treat leishmaniasis, a group of disease caused by parasites of the Leishmania type.
NivolumabA PD-1 blocking antibody used to treat melanoma, non small-cell lung cancer, renal cell cancer, head and neck cancer, and Hodgkin lymphoma.
PembrolizumabA PD-1 blocking antibody used to treat various types of cancer, including metastatic melanoma, non small-cell lung cancer, cervical cancer, head and neck cancer, and Hodgkin's lymphoma.
BlinatumomabAn antineoplastic antibody used to treat Philadelphia chromosome-negative relapsed or refractory B-cell precursor acute lymphoblastic leukemia (ALL).
IdelalisibAn antineoplastic kinase inhibitor used to treat chronic lymphocytic leukemia (CLL), relapsed follicular B-cell non-Hodgkin lymphoma (FL), and relapsed small lymphocytic lymphoma (SLL).
CeritinibAn antineoplastic kinase inhibitor used to treat anaplastic lymphoma kinase (ALK)-positive metastatic non-small cell lung cancer (NSCLC) in patients with inadequate clinical response or intolerance to crizotinib.
PalbociclibAn endocrine-based chemotherapeutic agent used in combination with other antineoplastic agents to treat HER2-negative and HR-positive advanced or metastatic breast cancer.
OlaparibA chemotherapeutic agent used to treat recurrent or advanced ovarian cancer and metastatic breast cancer in patients with specific mutations and prior history of chemotherapy.
LenvatinibA receptor tyrosine kinase inhibitor used for the treatment of metastatic thyroid cancer, advanced renal cell carcinoma in combination with everolimus, and unresectable hepatocellular carcinoma.
NintedanibA triple angiokinase inhibitor indicated for the treatment of idiopathic pulmonary fibrosis, systemic sclerosis-associated interstitial lung disease, and in combination with docetaxel for non-small cell lung cancer.
TegafurAn antineoplastic agent used in combination with other anticancer medications to treat advanced gastric and colorectal cancers.
IxazomibA monoclonal antibody used with other medications to treat multiple myeloma in patients who have received one other therapy already.
PirarubicinNot Annotated
AclarubicinNot Annotated
ZorubicinZorubicin is a drug of the anthracycline class - a class of medications that have historically demonstrated effective chemotherapy for a variety of cancer types.
TemoporfinA photosensitizer used to treat squamous cell carcinomas of the head and neck.
PrednimustinePrednimustine has been used in trials studying the treatment of Lymphoma.
TrofosfamideTrofosfamide has been used in trials studying the treatment of Ependymomas, Medulloblastomas, Sarcoma, Soft Tissue, Supratentorial PNETs, and Recurrent Brain Tumors.
MitoguazoneMitoguazone has been used in trials studying the treatment of Lymphoma, HIV Infections, and Lymphoma, Non-Hodgkin.
NimustineNimustine has been used in trials studying the treatment of Glioblastoma.
TreosulfanTreosulfan is under investigation in Allogeneic Haematopoietic Stem Cell Transplantation. Treosulfan has been investigated for the treatment of Lymphoblastic Leukemia, Acute, Childhood.
CediranibFor the treatment of liver cancer, advanced non-small cell lung cancer (NSCLC), advanced colorectal cancer (CRC) and other solid tumors.
Gemtuzumab ozogamicinA monoclonal anti-CD33 antibody used to treat CD33-positive acute myeloid leukemia.
TiazofurineTiazofurine has potential clinical use in cancer treatment as it is a potential inhibitor of Inosine- 5’-monophosphate (IMP) dehydrogenase .
TriaziquoneNot Annotated
DemecolcineNot Annotated
EtoglucidNot Annotated
MitobronitolNot Annotated
SemustineNot Annotated
CarboquoneNot Annotated
RanimustineNot Annotated
LeuprolideA peptide-based GnRH receptor superagonist used for the palliative treatment of prostate cancer, uterine leiomyomata, endometriosis, and central precocious puberty.
AldesleukinA recombinant analog of interleukin-2 used to induce an adaptive immune response in the treatment of renal cell carcinoma.
AlemtuzumabA monoclonal anti-CD52 antibody used in the treatment of B-cell chronic lymphocytic leukemia and relapsing forms of multiple sclerosis.
Megestrol acetateA progestin that is administered orally to treat anorexia and cachexia or serious unexplained weight loss and is also used as an antineoplastic agent to treat certain types of malignancy.
LenalidomideA thalidomide derivative used to treat multiple myeloma and anemia in low to intermediate risk myelodysplastic syndrome.
FlutamideAn antiandrogen used for locally confined stage B2-C and D-2 metastatic prostate carcinoma.
NilutamideAn antineoplastic hormone used to treat prostate cancer.
TamoxifenA selective estrogen receptor modulator used to treat estrogen receptor positive breast cancer, reduce the risk of invasive breast cancer following surgery, or reduce the risk of breast cancer in high risk women.
FulvestrantAn estrogen receptor antagonist used to treat HR+ breast cancer that may also be HER2-.
ExemestaneAn aromatase inhibitor used to treat breast cancer in postmenopausal women after treatment with tamoxifen.
LetrozoleAn aromatase inhibitor used to treat breast cancer in postmenopausal women.
BicalutamideAn androgen receptor inhibitor used to treat Stage D2 metastatic carcinoma of the prostate.
AnastrozoleA competitive, selective, non-steroidal aromatase inhibitor used as adjuvant therapy for the treatment of hormone receptor-positive breast cancer in postmenopausal women.
EverolimusA mammalian target of rapamycin (mTOR) kinase inhibitor used to treat various types of malignancies.
NelarabineA purine nucleoside analog and antineoplastic agent used for the treatment of with acute T-cell lymphoblastic leukemia and T-cell lymphoblastic lymphoma with inadequate clinical response to prior chemotherapeutic treatments.
NilotinibA kinase inhibitor used for the chronic phase treatment of Chronic Myeloid Leukemia (CML) that is Philadelphia chromosome positive and for the treatment of CML that is resistant to therapy containing imatinib.
VandetanibAn antineoplastic kinase inhibitor used to treat symptomatic or progressive medullary thyroid cancer in patients with unresectable locally advanced or metastatic disease.
IpilimumabA human cytotoxic T-lymphocyte antigen 4 (CTLA-4) blocking antibody used to treat metastatic or unresectable melanoma.
PazopanibAn antineoplastic agent used in the treatment of advanced renal cell cancer and advanced soft tissue sarcoma in patients with prior chemotherapy.
CatumaxomabFor use in the management of malignant ascites tumours via intraperitoneal infusion where standard therapy is not available or feasible [FDA Label].
BosutinibAn antineoplastic agent used for the treatment of chronic, accelerated, or blast phase Philadelphia chromosome-positive (Ph+) chronic myelogenous leukemia (CML) in adults with inadequate clinical response to other treatments.
AxitinibAn oral VEGFR and kinase inhibitor used for the treatment of advanced renal cell carcinoma after failure of one prior systemic therapy.
OfatumumabAn anti-CD20 antibody used for the treatment of chronic lymphocytic leukemia (CLL) in selected patients with certain treatment histories and responsiveness to anticancer medications.
CabazitaxelAn antineoplastic agent used for the treatment of hormone-refractory metastatic prostate cancer previously treated with a docetaxel-containing treatment regimen.
VismodegibA hedgehog pathway inhibitor used to treat patients with locally advanced or metastatic basal cell carcinoma.
CrizotinibA receptor tyrosine kinase inhibitor used to treat metastatic non-small cell lung cancer (NSCLC) where the tumors have been confirmed to be anaplastic lymphoma kinase (ALK), or ROS1-positive.
Brentuximab vedotinA CD30-directed antibody-drug conjugate used to treat various types of lymphoma.
EribulinA microtubule inhibitor used to treat metastatic breast cancer and metastatic or unresectable liposarcoma.
RuxolitinibA kinase inhibitor used to treat various types of myelofibrosis, polycythemia vera in patients who have not responded to or cannot tolerate hydroxyurea, and to treat graft-versus-host disease in cases that are refractory to steroid treatment.
VemurafenibA kinase inhibitor used to treat patients with Erdheim-Chester Disease who have the BRAF V600 mutation, and melanoma in patients who have the BRAF V600E mutation.
CarfilzomibA proteasome inhibitor used either alone or in conjunction with a chemotherapy regimen to treat patients with relapsed or refractory multiple myeloma.
RegorafenibA kinase inhibitor used to treat patients with metastatic colorectal cancer, unresectable, locally advanced, or metastatic gastrointestinal stromal tumors, and hepatocellular carcinoma.
AfatinibAn antineoplastic agent used for the treatment of locally advanced or metastatic non-small cell lung cancer (NSCLC) with non-resistant EGFR mutations or resistance to platinum-based chemotherapy.
IbrutinibAn antineoplastic agent used to treat chronic lymphocytic leukemia, mantle cell lymphoma, and Waldenstrom's Macroglobulinemia.
NecitumumabA monoclonal antibody used to treat metastatic squamous non-small cell lung cancer.
AbirateroneAn antiandrogen used in the treatment of prostate cancer.
MidostaurinAn antineoplastic agent used to treat high-risk acute myeloid leukemia (AML) with specific mutations, aggressive systemic mastocytosis (ASM), systemic mastocytosis with associated hematologic neoplasm (SM-AHN), or mast cell leukemia (MCL).
TriptorelinA GnRH agonist indicated for the palliative treatment of advanced prostate cancer.
PomalidomideA thalidomide analogue used in combination with dexamethasone to treat patients with multiple myeloma.
OsimertinibA tyrosine kinase inhibitor used in the treatment of certain types of non-small cell lung carcinoma.
DaratumumabA CD38-directed cytolytic antibody used alone or as an adjunct drug in the treatment of multiple myeloma.
TretinoinA vitamin A derivative used to treat acne vulgaris, certain types of promyelocytic leukemia, and fine wrinkles.
GoserelinA synthetic analog of luteinizing hormone-releasing hormone used to treat breast cancer and prostate cancer by reducing secretion of gonadotropins from the pituitary.
TositumomabA monoclonal anti-CD20 antibody used to treat B-cell non-Hodgkin's lymphoma via a conjugated radioactive isotope.
OctreotideA peptide drug used to treat acromegaly as well as diarrhea associated with metastatic carcinoid tumors and vasoactive intestinal peptide secreting tumors.
CabergolineA dopamine receptor agonist used for the treatment of hyperprolactinemic conditions due to various causes.
ChlorotrianiseneUsed to treat symptoms of menopause, deficiencies in ovary function (including underdevelopment of female sexual characteristics and some types of infertility), and in rare cases, prostate cancer. Chlorotrianisene may also...
Pamidronic acidA bisphosphonate used to treat Paget's disease, to treat hypercalcemia of malignancy, and to treat osteolytic bone lesions.
FloxuridineAn antimetabolite used as palliative management for liver metastases of gastrointestinal malignancy.
AminoglutethimideAn adrenocortical steroid synthesis inhibitor used in the treatment of Cushing's syndrome.
ToremifeneA first generation nonsteroidal selective estrogen receptor modulator used to treat certain breast cancers.
Medroxyprogesterone acetateA progestin used as a contraceptive and in the treatment of secondary amenorrhea, abnormal uterine bleeding, pain from endometriosis, endometrial and renal carcinomas, paraphilia in males, and GnRH-dependent precocious puberty.
PrednisoneA corticosteroid used to treat inflammation or immune-mediated reactions and to treat endocrine or neoplastic diseases.
ImiquimodA toll-like receptor 7 agonist used to treat non hyperkeratotic, non hypertrophic actinic keratosis, basal cell carcinoma, genital or perianal warts, and condyloma acuminata.
Uracil mustardUsed for its antineoplastic properties.
PrednisoloneA glucocorticoid used to treat adrenocortical insufficiency, inflammatory conditions, and some cancers.
TestolactoneA medication used to treat advanced breast cancer.
MethylprednisoloneA corticosteroid used to treat inflammation or immune reactions across a variety of organ systems, endocrine conditions, and neoplastic diseases.
ThalidomideA medication used to treat newly diagnosed multiple myeloma and erythema nodosum leprosum.
TrilostaneUsed in the treatment of Cushing's syndrome. It is normally used in short-term treatment until permanent therapy is possible.
DexamethasoneA glucocorticoid available in various modes of administration that is used for the treatment of various inflammatory conditions, including bronchial asthma, as well as endocrine and rheumatic disorders.
8-azaguanine8-azaguanine is one of the early purine analogs showing antineoplastic activity. It functions as an antimetabolite and is easily incorporated into ribonucleic acids.
7-HydroxystaurosporineNot Available
HadacidinNot Available
2-MethoxyestradiolFor the treatment of breast cancer and inflammatory diseases such as rheumatoid arthritis.
GeldanamycinNot Available
FumagillinNot Available
PatupiloneInvestigated for use/treatment in ovarian cancer, lung cancer, brain cancer, breast cancer, and gastric cancer.
Sparfosic acidSparfosic acid is a solid. This compound belongs to the n-acyl-alpha amino acids. These are compounds containing an alpha amino acid which bears an acyl group at the terminal nitrogen...
AlvocidibInvestigated for use/treatment in esophageal cancer, leukemia (lymphoid), lung cancer, liver cancer, and lymphoma (unspecified).
2-(4-Chlorophenyl)-5-QuinoxalinecarboxamideNot Available
Rhodamine 6GNot Available
BatimastatNot Available
3,4-Dihydroxybenzoic AcidNot Available
SparsomycinAn antitumor antibiotic produced by Streptomyces sparsogenes. It inhibits protein synthesis in 70S and 80S ribosomal systems. [PubChem]
TretazicarTretazicar is under investigation in clinical trial NCT00746590 (Study of Anti-tumour Effects and Safety of Prolarix™ in Hepatocellular Carcinoma).
SeocalcitolNot Available
NebularineNot Available
AfimoxifeneFor the potential treatment of menstrual-cycle related mastalgia, fibrocystic breast disease, breast disease, gynecomastia and Keloid scarring.
FleroxacinFleroxacin is a broad-spectrum antimicrobial fluoroquinolone.
MetoprineNot Available
CamptothecinInvestigated for the treatment of cancer.
SuraminFor treatment of human sleeping sickness, onchocerciasis and other diseases caused by trypanosomes and worms.
UrethaneUrethane, formerly marketed as an inactive ingredient in Profenil injection, was determined to be carcinogenic and was removed from the Canadian, US, and UK markets in 1963.
Cyproterone acetateA steroid used in combination with ethinyl estradiol to treat women with severe acne and symptoms of androgenization. Also used alone at much higher doses for palliative treatment of patients with prostate cancer
TirapazamineFor the treatment of head and neck cancer.
HalofuginoneFor the treatment of scleroderma, cancer, and restenosis.
VapreotideFor the treatment of esophageal variceal bleeding in patients with cirrhotic liver disease and has also shown efficacy in the treatment of patients with AIDS-related diarrhea.
ThymalfasinIndicated as an adjuvant for influenza vaccine in elderly patients and as an adjuvant for both influenza and hepatitis B vaccines in chronic hemodialysis patients who failed to achieve adequate...
RanpirnaseFor the treatment of various forms of cancer.
PirfenidoneAn agent used for the treatment of idiopathic pulmonary fibrosis (IPF).
TipifarnibInvestigated for use/treatment in colorectal cancer, leukemia (myeloid), pancreatic cancer, and solid tumors.
TroxacitabineInvestigated for use/treatment in leukemia (myeloid).
AmonafideInvestigated for use/treatment in breast cancer, ovarian cancer, and prostate cancer.
FenretinideInvestigated for use/treatment in macular degeneration.
TetrathiomolybdateInvestigated for use/treatment in liver disease and pulmonary fibrosis.
ElsamitrucinInvestigated for use/treatment in lymphoma (non-hodgkin's).
Gallium nitrateA medication indicated for cancer-related hypercalcemia.
EcabetFor the treatment of reflux oesophagitis and peptic ulcer disease.
CanertinibInvestigated for use/treatment in breast cancer and lung cancer.
Motexafin gadoliniumInvestigated for use/treatment in brain cancer, cancer/tumors (unspecified), lung cancer, and lymphoma (non-hodgkin's).
AlanosineInvestigated for use/treatment in brain cancer and cancer/tumors (unspecified).
PalifosfamideInvestigated for use/treatment in cancer/tumors (unspecified), lymphoma (unspecified), and sarcoma.
OglufanideInvestigated for use/treatment in hepatitis (viral, C).
IrofulvenInvestigated for use/treatment in brain cancer, breast cancer, endometrial cancer, liver cancer, lung cancer, ovarian cancer, pancreatic cancer, pediatric indications, prostate cancer, and sarcoma.
KOS-1584Investigated for use/treatment in solid tumors.
TranscrocetinateInvestigated for use/treatment in cancer/tumors (unspecified), hemorrhage, hypoxia, respiratory failure, and strokes.
RubitecanInvestigated for use/treatment in pancreatic cancer, leukemia (unspecified), melanoma, ovarian cancer, and cancer/tumors (unspecified).
GarenoxacinInvestigated for use/treatment in bacterial infection.
PlevitrexedInvestigated for use/treatment in pancreatic cancer, solid tumors, gastric cancer, lung cancer, and colorectal cancer.
SeliciclibInvestigated for use/treatment in breast cancer, lung cancer, lymphoma (unspecified), multiple myeloma, leukemia (lymphoid), and cancer/tumors (unspecified).
EflornithineA medication used topically to reduce unwanted facial hair growth in women. The postulated mechanism of action is through irreversible inhibition of ornithine decarboxylase (ODC) in the skin.
ExisulindInvestigated for use/treatment in adenomatous polyposis coli, lung cancer, prostate cancer, colon polyps, Barrett's esophagus disease, and pediatric indications.
MaxacalcitolNot Annotated
AnnamycinInvestigated for use/treatment in breast cancer and leukemia (unspecified).
EndostatinInvestigated for use/treatment in cancer/tumors (unspecified), macular degeneration, and diabetic retinopathy.
TezacitabineInvestigated for use/treatment in colorectal cancer, lung cancer, leukemia (unspecified), and gastric cancer.
SemaxanibInvestigated for use/treatment in colorectal cancer and lung cancer.
DiethylnorspermineInvestigated for use/treatment in renal cell carcinoma, pancreatic cancer, melanoma, and lung cancer.
SqualamineInvestigated for use/treatment in ovarian cancer, lung cancer, and macular degeneration.
PorfiromycinInvestigated for use/treatment in head and neck cancer.
MethyltestosteroneA synthetic anabolic steroid used for the replacement therapy in conditions associated with testosterone deficiencies in males, such as hypogonadism, and treatment of advancing inoperable metastatic breast cancer in females.
Ginsenoside CNot Available
BesifloxacinA fluoroquinolone antibiotic agent used for the treatment of bacterial conjunctivitis.
Hydroxyprogesterone caproateA synthetic progestin used for the prevention of spontaneous preterm births in singleton pregnancies in women who have previously had a spontaneous preterm birth.
LanreotideA somatostatin analog used for the treatment of unresectable, well- or moderately-differentiated, locally advanced or metastatic gastroenteropancreatic neuroendocrine tumors and acromegaly.
Phenylbutyric acidAn agent indicated for the adjunctive therapy for the management of chronic urea cycle disorders due to deficiencies in specific enzymes, including the neonatal-onset deficiency and late-onset disease with a history of hyperammonemic encephalopathy.
VeliparibNot Available
HexestrolA synthetic estrogen that has been used as a hormonal antineoplastic agent.
NocodazoleNocodazole is an antineoplastic agent which exerts its effect by depolymerizing microtubules.
PuromycinPuromycin is an antibiotic that prevents bacterial protein translation. It is utilized as a selective agent in laboratory cell cultures. Puromycin is toxic to both prokaryotic and eukaryotic cells, resulting...
FormestaneFor the treatment of estrogen-receptor positive breast cancer in post-menopausal women.
Radium Ra 223 dichlorideA radiopharmaceutical agent used to treat patients with castration-resistant prostate cancer, symptomatic bone metastases and no known visceral metastatic disease.
FlumequineFlumequine is a synthetic chemotherapeutic antibiotic of the fluoroquinolone drug class used to treat bacterial infections.
SiltuximabAn interleukin antagonist used to treat multicentric Castleman's disease (MCD) in patients who are HIV and HHV-8 negative.
PodophyllinA cytotoxic agent used for the removal of soft genital (venereal) warts (condylomata acuminata).
DienogestAn oral progestin used for the treatment of endometriosis as monotherapy or contraception in combination with ethinylestradiol.
NiguldipineNiguldipine is a calcium channel blocker drug (CCB) with a1-adrenergic antagonist properties.
RoquinimexRoquinimex is investigated to be used as a treatment of a number of cancers and autoimmune conditions. As well, roquinimex is researched to be used as adjuvant therapy after bone...
RabusertibRabusertib has been used in trials studying the treatment of Cancer, Solid Tumors, Advanced Cancer, Pancreatic Neoplasms, and Non Small Cell Lung Cancer.
CurcuminNo approved therapeutic indications.
2-chloroethyl-3-sarcosinamide-1-nitrosourea2-chloroethyl-3-sarcosinamide-1-nitrosourea has been used in trials studying the treatment of Colorectal Cancer, Brain and Central Nervous System Tumors, and Unspecified Adult Solid Tumor, Protocol Specific.
MisonidazoleMisonidazole is under investigation in clinical trial NCT00038038 (Assessment of Head and Neck Tumor Hypoxia Using 18F-Fluoromisonidazole).
Bryostatin 1Bryostatin 1 has been investigated for the treatment of HIV Infection and Alzheimer's Disease.
TalazoparibA poly-ADP ribose polymerase inhibitor used to treat HER2-, BRCA mutated locally advanced or metastatic breast cancer.
TremelimumabTremelimumab is under investigation for the treatment of Mesothelioma, Liver Cancer, Liver Neoplasms, Liver Cell Caricinoma, and HepatoCellular Carcinoma. Tremelimumab has been investigated in Part C: Malignant Mesothelioma and Part...
NiraparibA poly-ADP ribose polymerase inhibitor used to treat recurrent epithelial ovarian, fallopian tube, or primary peritoneal cancer responding to platinum based chemotherapy.
SaracatinibSaracatinib has been investigated for the treatment of Cancer, Osteosarcoma, Ovarian Cancer, Fallopian Tube Cancer, and Primary Peritoneal Cancer.
TalaporfinTalaporfin has been investigated for the treatment of Port-Wine Stain and Benign Prostatic Hyperplasia.
CrenolanibCrenolanib is under investigation for the treatment of Diffuse Intrinsic Pontine Glioma and Progressive or Refractory High-Grade Glioma.
EntinostatEntinostat is under investigation for the treatment and other of Volunteers, Breast Cancer, Human Volunteers, and Normal Volunteers. Entinostat has been investigated for the treatment of Non-Small Lung Cancer, Epigenetic...
Acridine CarboxamideAcridine Carboxamide has been used in trials studying the treatment of Lung Cancer and Brain and Central Nervous System Tumors.
InfigratinibInfigratinib is under investigation for the treatment of Head and Neck Squamous Cell Carcinoma.
EfatutazoneEfatutazone has been used in trials studying the treatment of Lymphoma, Liposarcoma, Solid Tumors, Multiple Myeloma, and Recurrent Thyroid Cancer, among others.
6-O-benzylguanine6-O-benzylguanine has been used in trials studying the treatment of HIV Infection, Adult Gliosarcoma, Adult Glioblastoma, Stage I Adult Hodgkin Lymphoma, and Stage II Adult Hodgkin Lymphoma, among others.
CarboxyamidotriazoleCarboxyamidotriazole has been used in trials studying the treatment of Lymphoma, Lung Cancer, Breast Cancer, Kidney Cancer, and Ovarian Cancer, among others.
TriptolideTriptolide has been used in trials studying the treatment of HIV, Crohn's Disease, Intestinal Diseases, Gastrointestinal Diseases, and Digestive System Diseases, among others.
BroxuridineBroxuridine has been used in trials studying the treatment of Leukemia, Stage I Prostate Cancer, Stage IIB Prostate Cancer, and Stage IIA Prostate Cancer.
TrebananibTrebananib is under investigation for the treatment of Ovarian Cancer, Peritoneal Cancer, and Fallopian Tube Cancer. Trebananib has been investigated for the treatment of Cancer, Oncology, Carcinoma, Metastases, and Colon...
AnecortaveAnecortave is under investigation in clinical trial NCT00691717 (Anecortave Acetate Safety in Patients With Open-Angle Glaucoma or Ocular Hypertension).
VesnarinoneVesnarinone has been used in trials studying the treatment of HIV Infections and Sarcoma, Kaposi.
MafosfamideMafosfamide has been used in trials studying the treatment of Lymphoma, Leukemia, Meningeal Neoplasm, and Brain and Central Nervous System Tumors.
LCL-161LCL161 has been used in trials studying the treatment of Leukemia, Neoplasms, Solid Tumors, Breast Cancer, and Ovarian Cancer, among others.
TaselisibTaselisib has been used in trials studying the treatment and basic science of LYMPHOMA, Breast Cancer, Ovarian Cancer, Solid Neoplasm, and HER2/Neu Negative, among others.
Epigallocatechin gallateEpigallocatechin gallate has been investigated for the treatment of Hypertension and Diabetic Nephropathy.
NamitecanNamitecan has been used in trials studying the treatment of Solid Tumors.
DuligotuzumabDuligotuzumab has been used in trials studying the treatment of Neoplasms, Colorectal Cancer, Head and Neck Cancer, and Epithelial Tumors, Malignant.
CordycepinCordycepin has been used in trials studying the treatment of Leukemia.
BinetrakinBinetrakin has been used in trials studying the treatment of HIV Infections, Sarcoma, Kaposi, Non-Hodgkin's Lymphoma (NHL), Myelodysplastic Syndrome (MDS), and Leukemia, Acute Myelogenous (AML), among others.
ExatecanExatecan has been used in trials studying the treatment of Sarcoma, Leukemia, Lymphoma, Lung Cancer, and Liver Cancer, among others.
LurtotecanLurtotecan is under investigation in clinical trial NCT00022594 (Liposomal Lurtotecan in Treating Patients With Metastatic or Locally Recurrent Head and Neck Cancer).
KRN-7000KRN7000 has been used in trials studying the treatment of Lung Cancer, Chronic Hepatitis C, Hepatitis B, Chronic, Unspecified Adult Solid Tumor, Protocol Specific, and Prevention of GvHD in Patients...
EpofolateEpofolate has been used in trials studying the treatment of Advanced Solid Tumors.
OBP-801OBP-801 has been used in trials studying the treatment of Solid Tumor.
RucaparibAn anti-cancer agent used to treat recurrent ovarian, fallopian tube, or peritoneal cancer.
NavitoclaxNavitoclax has been used in trials studying the treatment and basic science of Solid Tumors, Non-Hodgkin's Lymphoma, EGFR Activating Mutation, Chronic Lymphoid Leukemia, and Hematological Malignancies, among others. Navitoclax is...
BizelesinBizelesin has been used in trials studying the treatment of Unspecified Adult Solid Tumor, Protocol Specific.
IndirubinIndirubin is under investigation in clinical trial NCT01735864 (Dosage Determination Trial for Indigo Naturalis Extract in Oil Ointment).
MerestinibMerestinib has been used in trials studying the treatment of Cancer, Solid Tumor, Advanced cancer, ColoRectal Cancer, and Metastatic Cancer, among others.
10-hydroxycamptothecin10-hydroxycamptothecin is under investigation in clinical trial NCT00956787 (Study of AR-67 (DB-67) in Myelodysplastic Syndrome (MDS)).
SulforaphaneSulforaphane is under investigation for the treatment of Autism Spectrum Disorder. It is a naturally occurring isothiocyanate found in high concentration in a variety of broccoli.
BelotecanBelotecan has been investigated for the treatment of Epithelial Ovarian Cancer.
TaurolidineTaurolidine has been investigated for the prevention of Central Venous Catheter, Home Parenteral Nutrition, and Catheter-Related Infections.
9-aminocamptothecinAminocamptothecin has been used in trials studying the treatment of Lymphoma, Gastric Cancer, Ovarian Cancer, Esophageal Cancer, and Ovarian Neoplasms, among others.
MolgramostimMolgramostim has been used in trials studying the treatment of Bronchiectasis, Cystic Fibrosis, Pulmonary Alveolar Proteinosis, Acute Respiratory Distress Syndrome, and Autoimmune Pulmonary Alveolar Proteinosis.
OltiprazOltipraz has been used in trials studying the treatment and prevention of Lung Cancer, Liver Fibrosis, Liver Cirrhosis, and Non-alcoholic Fatty Liver Disease.
PyrazoloacridinePyrazoloacridine has been used in trials studying the treatment of Lung Cancer, Liver Cancer, Breast Cancer, Melanoma (Skin), and Metastatic Cancer, among others.
FosbretabulinFosbretabulin has been investigated for the treatment of Anaplastic Thyroid Cancer.
ApaziquoneApaziquone has been investigated for the treatment of Bladder Cancer and Bladder Neoplasms.
CombretastatinCombretastatin has been investigated for the treatment of Anaplastic Thyroid Cancer.
MizoribineMizoribine has been investigated for the treatment of Rheumatoid Arthritis.
OnapristoneOnapristone has been used in trials studying the treatment of Prostate Cancer, Recurrent Prostate Cancer, Metastatic Prostate Cancer, Androgen-independent Prostate Cancer, and Progesterone Receptor Positive Tumor: Max 1 Line of...
SoblidotinSoblidotin has been used in trials studying the treatment of Sarcoma, Lung Cancer, and Unspecified Adult Solid Tumor, Protocol Specific.
SalirasibSalirasib has been used in trials studying the diagnostic of Carcinoma, Non-Small-Cell Lung.
GusperimusGusperimus has been used in trials studying the treatment of Lupus Nephritis, Wegeners Granulomatosis, and Wegener's Granulomatosis.
Phenethyl IsothiocyanatePhenethyl Isothiocyanate has been used in trials studying the prevention and treatment of Leukemia, Lung Cancer, Tobacco Use Disorder, and Lymphoproliferative Disorders.
MethylselenocysteineMethylselenocysteine has been used in trials studying the prevention of Prostate Carcinoma and No Evidence of Disease.
Dolastatin 10Dolastatin 10 has been used in trials studying the treatment of Sarcoma, Leukemia, Lymphoma, Liver Cancer, and Kidney Cancer, among others.
EtanidazoleEtanidazole has been used in trials studying the diagnostic of Adult Ependymoma, Malignant Ascites, Adult Gliosarcoma, Adult Mixed Glioma, and Adult Glioblastoma, among others.
LometrexolLometrexol has been used in trials studying the treatment of Lung Cancer, Drug/Agent Toxicity by Tissue/Organ, and Unspecified Adult Solid Tumor, Protocol Specific.
Buthionine SulfoximineButhionine Sulfoximine has been used in trials studying the treatment of Neuroblastoma and Melanoma (Skin).
DianhydrogalactitolDianhydrogalactitol has been used in trials studying the treatment of GBM, Glioma, Glioblastoma, Brain Cancer, and Glioblastoma Multiforme.
Indole-3-carbinolIndole 3 Carbinol is under investigation in clinical trial NCT00033345 (Indole-3-Carbinol in Preventing Breast Cancer in Nonsmoking Women Who Are at High Risk For Breast Cancer).
FiacitabineFiacitabine has been used in trials studying the treatment of HIV Infections and Cytomegalovirus Infections.
NolatrexedNolatrexed is under investigation in clinical trial NCT00012324 (Nolatrexed Dihydrochloride Compared With Doxorubicin in Treating Patients With Recurrent or Unresectable Liver Cancer).
MitolactolMitolactol has been used in trials studying the treatment of Brain and Central Nervous System Tumors.
PinometostatPinometostat has been used in trials studying the treatment of Leukemia, Acute Leukemias, Acute Myeloid Leukemia, Myelodysplastic Syndrome, and Acute Lymphocytic Leukemia, among others.
DoxifluridineDoxifluridine has been investigated for the treatment of Stomach Cancer.
DidoxDidox has been used in trials studying the supportive care of Gastric Cancer.
PenclomedinePenclomedine has been used in trials studying the treatment of Lymphoma and Unspecified Adult Solid Tumor, Protocol Specific.
DeoxyspergualinDeoxyspergualin has been used in trials studying the treatment of Lupus Nephritis, Chronic Rejection, and Diabetes Mellitus, Type 1.
ActeosideActeoside is under investigation in clinical trial NCT02662283 (Validity and Security of Reh-acteoside Therapy for Patients of IgA Nephropathy).
HypericinHypericin is under investigation for the treatment of Cutaneous T-cell Lymphoma.
LiarozoleLiarozole has been used in trials studying the treatment of Ichthyosis, Lamellar.
SizofiranA beta-D-glucan obtained from the Aphyllophoral fungus Schizophyllum commune. It is used as an immunoadjuvant in the treatment of neoplasms, especially tumors found in the stomach. Sizofiran has been used...
NedaplatinUsed in the treatment of non-small cell lung cancer, small cell lung cancer, oesophygeal cancer, and head and neck cancers .
DaidzeinNot Annotated
LentinanNot Annotated
Oxolinic acidNot Annotated
VorozoleNot Annotated
IniparibNot Annotated
Coumermycin A1Not Annotated
Toyocamycin4-Amino-5-cyano-7-(D-ribofuranosyl)-7H- pyrrolo(2,3-d)pyrimidine. Antibiotic antimetabolite isolated from Streptomyces toyocaensis cultures. It is an analog of adenosine, blocks RNA synthesis and ribosome function, and is used mainly as a tool in biochemistry.
TretamineToxic alkylating agent used in industry; also as antineoplastic and research tool to produce chromosome aberrations and cancers.
MasoprocolUsed for the treatment of actinic keratoses (precancerous skin growths that can become malignant if left untreated).
AnagrelideA platelet-reducing agent used to treat thrombocythemia, and its related complications, secondary to myeloproliferative neoplasms.
Aminolevulinic acidA porphyrin precursor used to treat actinic keratosis of the face, scalp, and upper extremities, as well as to visualize a glioma.
Methyl aminolevulinateA porphyrin precursor used to treat non-hyperkeratotic, non-pigmented actinic keratosis of the face and scalp.
IxabepiloneA microtubule inhibitor administered in combination with capecitabine or alone in the treatment of metastatic or locally advanced breast cancer that has shown inadequate response to taxanes and anthracyclines.
Sitimagene ceradenovecIntended for the treatment of brain cancer.
VintafolideInvestigated for use/treatment in solid tumors.
RidaforolimusInvestigated for use/treatment in solid tumors, sarcoma, cancer/tumors (unspecified), endometrial cancer, prostate cancer, and bone metastases.
PralatrexateAn antineoplastic agent used for the treatment of relapsed or refractory peripheral T-cell lymphoma.
EfaproxiralNot Available
CabozantinibA tyrosine kinase inhibitor used to treat advanced renal cell carcinoma, hepatocellular carcinoma, and medullary thyroid cancer.
DinutuximabAn immunotherapeutic agent used in combination with other immunomodulating agents to treat high-risk neuroblastoma in pediatric patients who achieve at least a partial response to prior first-line multiagent, multimodality therapy.
SonidegibAn antineoplastic agent used for the treatment of locally advanced recurrent basal cell carcinoma (BCC) following surgery and radiation therapy, or in cases where surgery or radiation therapy are not appropriate.
MasitinibMasitinib is a tyrosine-kinase inhibitor used in the treatment of mast cell tumors in dogs. It has been available in Europe since 2009, under the brand name Masivet. In the...
VinflunineA vinca alkaloid used to treat advanced or metastatic transitional cell carcinoma of the urothelial tract after a platinum containing treatment has failed.
TivozanibTivozanib has been used in trials studying the treatment and basic science of Solid Tumors, Glioblastoma, Ovarian Cancer, Prostate Cancer, and Stage IV Disease, among others.
MannosulfanNot Annotated
EdrecolomabNot Annotated
Paclitaxel poliglumexNot Annotated
OblimersenNot Annotated
Interferon alfa-2bA form of recombinant human interferon used to treat hepatitis B and C infection, genital warts, hairy cell leukemia, follicular lymphoma, malignant melanoma, and AIDs-related Kaposi's sarcoma.
CobimetinibAn antineoplastic agent and selective inhibitor of the mitogen-activated extracellular kinase (MEK) pathway used to treat unresectable or metastatic melanoma.
Inotuzumab ozogamicinAn antibody-drug conjugate used to treat B-cell precursor acute lymphoblastic leukemia (ALL).
OlaratumabA platelet-derived growth factor receptor alpha blocking antibody used with doxorubicin to treat patients with certain types of soft tissue sarcoma (STS).
ElotuzumabAn antineoplastic agent and SLAMF7-directed immunostimulatory antibody used for the treatment of refractory multiple myeloma in combination with other antineoplastic agents.
DegarelixA GnRH receptor antagonist used in the management of advanced prostate cancer.
BuserelinA LHRH agonist used for the palliative treatment of hormone-dependent advanced carcinoma of the prostate gland in males and treatment of endometriosis in females.
Asparaginase Erwinia chrysanthemiAn asparagine specific enzyme used as part of a chemotherapeutic regimen to treat patients with acute lymphoblastic leukemia.
EnzalutamideAn androgen receptor inhibitor used to treat castration-resistant prostate cancer.
AlectinibA kinase inhibitor used to treat anaplastic lymphoma kinase positive metastatic non small cell lung cancer.
VenetoclaxA BCL-2 inhibitor used to treat chronic lymphocytic leukemia, small lymphocytic lymphoma, or acute myeloid leukemia.
AtezolizumabA monoclonal antibody used to treat advanced or metastatic urothelial carcinoma with disease progression during or up to 12 months after platinum-containing chemotherapy.
DurvalumabAn antineoplastic monoclonal antibody used to treat urothelial carcinoma and locally advanced, unresectable non-small cell lung cancer.
RibociclibA kinase inhibitor used to treat HR+, HER2- advanced or metastatic breast cancer.
AvelumabA monoclonal antibody used to treat metastatic merkel cell carcinoma, metastatic urothelial carcinoma, or renal cell carcinoma.
GenisteinCurrently Genistein is being studied in clinical trials as a treatment for prostate cancer.
TrifluridineA nucleoside metabolic inhibitor used to treat keratoconjunctivitis and epithelial keratitis caused by simplex virus, and as a part of chemotherapy for certain types of metastatic gastrointestinal cancers.
VincamineVincamine is a monoterpenoid indole alkaloid obtained from the leaves of Vinca minor with a vasodilatory property. Studies indicate that vincamine increases the regional cerebral blood flow.
PracinostatFor the treatment of various forms of cancer.
MocetinostatMocetinostat has been used in trials studying the treatment of Lymphoma, Urothelial Carcinoma, Relapsed and Refractory, Myelodysplastic Syndrome, and Metastatic Leiomyosarcoma, among others.
CUDC-907CUDC-907 has been used in trials studying the treatment of Lymphoma, Solid Tumors, BREAST CANCER, Multiple Myeloma, and NUT Midline Carcinoma, among others.
CG-200745Cg200745 has been used in trials studying the treatment of Solid Tumour.
RicolinostatRicolinostat is under investigation for the treatment of Breast Carcinoma and Metastatic Breast Cancer.
R-306465R306465 has been used in trials studying the treatment of Neoplasms.
AbexinostatAbexinostat has been used in trials studying the treatment of Sarcoma, Lymphoma, Leukemia, Lymphocytic, and Hodgkin Disease, among others. It is a novel, broad-spectrum hydroxamic acid-based inhibitor of histone deacetylase...
GivinostatGivinostat has been used in trials studying the treatment of Polycythemia Vera, Juvenile Idiopathic Arthritis, Duchenne Muscular Dystrophy (DMD), Chronic Myeloproliferative Neoplasms, and Polyarticular Course Juvenile Idiopathic Arthritis.
Valproic acidAn anticonvulsant used to control complex partial seizures and both simple and complex absence seizures.
BufexamacAn NSAID used to treat skin conditions like atopic eczema and inflammatory dermatoses.
TetrandrineNot Annotated
DofequidarDofequidar is an antineoplastic agent.
DexniguldipineNot Annotated
Paclitaxel trevatideInvestigated for use/treatment in brain cancer.
AldoxorubicinInvestigated for use/treatment in solid tumors.
Peginterferon alfa-2aA modified form of recombinant human interferon used to stimulate the innate antiviral response in the treatment of hepatitis B and C viruses.
TucidinostatInvestigated for use/treatment in cancer/tumors (unspecified).
CUDC-101CUDC-101 has been used in trials studying the treatment of Cancer, Tumors, Liver Cancer, Breast Cancer, and Gastric Cancer, among others.
Methylprednisolone hemisuccinateA water soluble corticosteroid used to treat severe allergic reactions, dermatologic diseases, endocrine disorders, gastrointestinal diseases, hematological disorders, neoplastic diseases, nervous system conditions, ophthalmic diseases, renal diseases, respiratory diseases, and rheumatic disorders.
Prednisone acetateNot Annotated
Combretastatin A4Not Annotated
Moxetumomab PasudotoxA CD22-specific antibody conjugated to a truncated exotoxin used to treat relapsed or refractory hairy cell leukemia in patients who have already been treated with a purine nucleoside analog and one other treatment.
PlatinumPlatinum is under investigation for the treatment of Metastatic Breast Cancer, Non-small Cell Lung Cancer, Gastric Large Cell Neuroendocrine Carcinoma, Colorectal Large Cell Neuroendocrine Carcinoma, and Pancreatic Large Cell Neuroendocrine...
DacomitinibA medication used to treat non small cell lung cancer with EGFR exon 19 deletion of exon 21 L858R substitution.
BrequinarNot Available
PiritreximPiritrexim has been used in trials studying the treatment of Bladder Cancer, Urethral Cancer, and Transitional Cell Cancer of the Renal Pelvis and Ureter.
7-ethyl-10-hydroxycamptothecinInvestigated for use/treatment in colorectal cancer.
TNP-470O-(chloroacetylcarbamoyl)fumagillol (TNP-470) has been used in trials studying the treatment of HIV Infections, Sarcoma, Kaposi, and Pancreatic Neoplasms.
Betulinic AcidBetulinic Acid has been used in trials studying the treatment of Dysplastic Nevus Syndrome.
GilteritinibAn AXL receptor tyrosine kinase inhibitor used to treat relapsed or refractory acute myeloid leukemia.
IMO-2055Investigated for use/treatment in renal cell carcinoma, solid tumors, and lung cancer.
TagraxofuspA CD123-directed cytotoxin used to treat plasmacytoid dendritic cell neoplasm.
VadimezanInvestigated for use/treatment in solid tumors, lung cancer, ovarian cancer, and prostate cancer.
GlasdegibA sonic hedgehog receptor inhibitor used to treat newly diagnosed acute myeloid leukemia in patients over 75 years who cannot receive intense chemotherapy.
PlitidepsinIntended for the treatment of various forms of cancer.
EpacadostatEpacadostat has been used in trials studying the treatment of HL, Melanoma, Glioblastoma, Mucosal Melanoma, and Ovarian Carcinoma, among others.
EncorafenibA kinase inhibitor used to treat unresectable or metastatic melanoma with specific mutations.
IcotinibIcotinib hydrochloride is a novel epidermal growth factor receptor (EGFR)–tyrosine kinase inhibitor, exhibits encouraging efficacy and tolerability in patients with advanced non-small-cell lung cancer (NSCLC) who failed previous chemotherapy.
NeratinibA protein kinase inhibitor used to treat breast cancer that over expresses the HER2 receptor.
RociletinibRociletinib has been used in trials studying the treatment and prevention of Nonsmall Cell Lung Cancer, Non-small Cell Lung Cancer, and Locally Advanced or Metastatic Non-small Cell Lung Cancer.
BinimetinibA medication used to treat metastatic melanoma with specific mutations.
VosaroxinVosaroxin is under investigation for the treatment of Leukemia, Myeloid, Acute.
AbemaciclibA medication used to treat HR+ HER2- advanced or metastatic breast cancer.
LorlatinibAn anaplastic lymphoma kinase inhibitor used to treat anaplastic lymphoma kinase positive metastatic non small cell lung cancer.
BrigatinibAn anaplastic lymphoma kinase inhibitor used to treat anaplastic lymphoma kinase positive metastatic non small cell lung cancer.
CopanlisibA medication used to treat relapsed follicular lymphoma who have attempted at least two other treatments.
MogamulizumabA monoclonal antibody used to treat relapsed or refractory mycosis fungoides or Sézary syndrome after attempting one other therapy.
OlmutinibFor use in treatment of metastatic T790M mutation positive non-small cell lung cancer .
EnasidenibAn isocitrate dehydrogenase-2 inhibitor used to treat relapsed or refractory acute myeloid leukemia with an isocitrate dehydrogenase-2 mutation.
Talimogene laherparepvecA genetically modified virus used to treat recurrent melanoma, or metastatic melanoma.
ErdafitinibA fibroblast growth factor receptor tyrosine kinase inhibitor used to treat locally advanced or metastatic urothelial carcinoma.
ONC-201ONC-201 is under investigation in clinical trial NCT03394027 (ONC201 in Recurrent/Refractory Metastatic Breast Cancer and Advanced Endometrial Carcinoma).
Human interleukin-2Human interleukin-2 is under investigation in clinical trial NCT03475134 (TIL-ACT After NMA Chemo With IL-2 and Nivo Rescue in mMEL).
Etirinotecan pegolEtirinotecan pegol is under investigation in clinical trial NCT01663012 (Phase II NKTR-102 In Bevacizumab-Resistant High Grade Glioma).
NUC-1031NUC-1031 is under investigation in clinical trial NCT03610100 (Acelarin First Line Randomised Pancreatic Study).
Perillyl alcoholPerillyl alcohol is under investigation in clinical trial NCT02704858 (Safety and Efficacy Study in Recurrent Grade IV Glioma).
Biochanin ABiochanin A is under investigation in clinical trial NCT02174666 (Isoflavone Treatment for Postmenopausal Osteopenia.).
PidilizumabPidilizumab is under investigation in clinical trial NCT01952769 (Anti PD1 Antibody in Diffuse Intrinsic Pontine Glioma).
BermekimabBermekimab is under investigation in clinical trial NCT01384630 (Safety, Pharmacokinetics, and Efficacy of RA-18C3 in Subjects With Moderate to Severe Psoriasis).
TefinostatTefinostat is under investigation in clinical trial NCT02759601 (Dose Escalation Trial of Tefinostat for Cancer Associated Inflamation in Hepatocellular Carcinoma (HCC)).
NanatinostatNanatinostat is under investigation in clinical trial NCT00697879 (Safety Study of the Histone Deacetylase Inhibitor, CHR-3996, in Patients With Advanced Solid Tumours).
ApalutamideAn androgen receptor inhibitor used to treat non metastatic, castration resistant prostate cancer.
AlpelisibAlpelisib is indicated in combination with fulvestrant to treat postmenopausal women, and men, with advanced or metastatic breast cancer.[Label] This cancer must be hormone receptor (HR)-positive, human epidermal growth factor...
TubercidinAn antibiotic purine ribonucleoside that readily substitutes for adenosine in the biological system, but its incorporation into DNA and RNA has an inhibitory effect on the metabolism of these nucleic...
TrimetrexateA folate antagonist used for the treatment of moderate-to-severe Pneumocystis carinii pneumonia (PCP) in immunocompromised patients as an alternative therapy in combination with leucovorin.
Epothilone DInvestigated for use/treatment in colorectal cancer, lung cancer, breast cancer, solid tumors, and prostate cancer.
MonastrolNot Available
GaliximabInvestigated for use/treatment in lymphoma (non-hodgkin's), psoriasis and psoriatic disorders, bone metastases, multiple myeloma, prostate cancer, and rheumatoid arthritis.
EpratuzumabInvestigated for use/treatment in leukemia (lymphoid), lymphoma (non-hodgkin's), and systemic lupus erythematosus.
OregovomabInvestigated for use/treatment in ovarian cancer.
BanoxantroneFor the treatment of various forms of cancer.
LabetuzumabLabetuzumab is a humanized monoclonal antibody used to treat cancer. Retrieved from "http://en.wikipedia.org/wiki/Labetuzumab"
BavituximabInvestigated for use/treatment in breast cancer, cancer/tumors (unspecified), HIV infection, hepatitis (viral, C), and solid tumors.
RindopepimutInvestigated for use/treatment in brain cancer.
PelitinibInvestigated for use/treatment in colorectal cancer and lung cancer.
FarletuzumabInvestigated for use/treatment in ovarian cancer.
VeltuzumabInvestigated for use/treatment in lymphoma (non-hodgkin's).
CT-011Investigated for use/treatment in cancer/tumors (unspecified).
Glembatumumab vedotinInvestigated for use/treatment in melanoma.
AV-412Investigated for use/treatment in cancer/tumors (unspecified).
FilanesibInvestigated for use/treatment in cancer/tumors (unspecified).
NimotuzumabInvestigated for use/treatment in head and neck cancer, brain cancer, pediatric indications, pancreatic cancer, lung cancer, and colorectal cancer.
AtrasentanInvestigated for use/treatment in prostate cancer and cancer/tumors (unspecified).
SapacitabineInvestigated for use/treatment in solid tumors, cutaneous t-cell lymphoma, myelodysplastic syndrome, and leukemia (lymphoid).
IndisulamInvestigated for use/treatment in lung cancer.
VolociximabInvestigated for use/treatment in solid tumors, renal cell carcinoma, melanoma, pancreatic cancer, lung cancer, and ovarian cancer.
FinafloxacinFinafloxacin is indicated for the treatment of acute otitis externa (AOE) with or without an otowick, caused by susceptible strains of Pseudomonas aeruginosa and Staphylococcus aureus in patients age 1...
ArtesunateArtesunate is an artemesinin derivative indicated for the initial treatment of severe malaria.
SilibininCurrently being tested as a treatment of severe intoxications with hepatotoxic substances, such as death cap (Amanita phalloides) poisoning.
ConatumumabConatumumab has been used in trials studying the treatment of Sarcoma, Lymphoma, Oncology, Colon Cancer, and Rectal Cancer, among others.
DactolisibDactolisib has been used in trials studying the treatment of Cancer, Solid Tumor, Renal Cancer, Breast Cancer, and Cowden Syndrome, among others.
OrtataxelOrtataxel has been used in trials studying the treatment of Lymphoma, Lung Cancer, Glioblastoma, and Kidney Cancer.
IlorasertibIlorasertib has been used in trials studying the treatment of Myelodysplasia, Solid Neoplasm, Advanced Cancers, Advanced Solid Tumors, and Acute Myelogenous Leukemia, among others.
EndostarEndostar is under investigation for the treatment of Nasopharyngeal Carcinoma. Endostar has been investigated for the treatment of Non-small Cell Lung Cancer.
GSK-2636771GSK2636771 has been used in trials studying the treatment of CANCER, LYMPHOMA, Solid Neoplasm, Recurrent Solid Neoplasm, and Advanced Malignant Neoplasm, among others.
GuadecitabineGuadecitabine is under investigation for the treatment of Previously Treated Metastatic Colorectal Cancer.
RilotumumabRilotumumab has been investigated for the treatment of Cancer, Lung Cancer, Solid Tumors, Gastric Cancer, and Prostate Cancer, among others.
TesevatinibTesevatinib has been used in trials studying the treatment of Cancer, Stomach Cancer, Brain Metastases, Esophageal Cancer, and Leptomeningeal Metastases, among others. Tesevatinib is a potent inhibitor of multiple RTKs...
NaquotinibNaquotinib has been used in trials studying the treatment of Solid Tumors, Non-small Cell Lung Cancer, Non-Small-Cell Lung Cancer (NSCLC), Epidermal Growth Factor Receptor Mutations, and Epidermal Growth Factor Receptor...
Lorvotuzumab mertansineLorvotuzumab mertansine has been used in trials studying the treatment of SCLC, Leukemia, Ovarian Cancer, Multiple Myeloma, and Merkel Cell Carcinoma, among others.
RigosertibRigosertib has been used in trials studying the treatment and basic science of MDS, RAEB, Cancer, Hepatoma, and Neoplasms, among others.
ZalutumumabZalutumumab is a fully human IgG1 monoclonal antibody designed to bind with selectivity to the epidermal growth factor receptor (EGFR). Zalutumumab has been investigated for the treatment of Squamous Cell...
SagopiloneSagopilone has been used in trials studying the treatment of Melanoma, Neoplasms, CNS Disease, Breast Cancer, and Breast Neoplasms, among others. It is a so-called fully synthetic epothilone and is...
DacetuzumabInvestigated for use/treatment in lymphoma (non-hodgkin's) and multiple myeloma.
PU-H71PU-H71 has been used in trials studying the treatment of LYMPHOMA, Solid Tumors, Metastatic Solid Tumor, and Myeloproliferative Neoplasms (MPN).
BeloranibBeloranib has been used in trials studying the treatment of Obesity, Over-weight, Type 2 Diabetes, Craniopharyngioma, and Hypothalamic Injury, among others.
IntetumumabIntetumumab has been used in trials studying the treatment of Melanoma.
EcromeximabEcromeximab has been used in trials studying the treatment of Cutaneous Melanoma and Metastatic Melanoma.
RebastinibRebastinib has been used in trials studying the treatment of Chronic Myeloid Leukemia. It is an inhibitor of Tie2 tyrosine kinase receptor and an antineoplastic agent.
TocladesineTocladesine has been used in trials studying the treatment of Colorectal Cancer and Multiple Myeloma and Plasma Cell Neoplasm.
X-396X-396 has been used in trials studying the treatment of Advanced Solid Tumors and Non-small Cell Lung Cancer.
IvosidenibAn isocitrate dehydrogenase-1 inhibitor used to treat acute myeloid leukemia with a susceptible mutation.
CemiplimabA programmed death receptor-1 blocking antibody used to treat metastatic cutaneous squamous cell carcinoma.
RivoceranibRivoceranib is under investigation in clinical trial NCT02726854 (Apatinib as Second-line Treatment of Advanced Pancreatic Cancer).
AZD-5991AZD-5991 is under investigation in clinical trial NCT03218683 (Study of AZD5991 in Relapsed or Refractory Haematologic Malignancies.).
EnsartinibEnsartinib is under investigation in clinical trial NCT03420508 (Treating Patients With Melanoma and ALK Alterations With Ensartinib).
LintuzumabLintuzumab is under investigation in clinical trial NCT00016159 (Chemotherapy Plus Monoclonal Antibody in Treating Patients With Acute Promyelocytic Leukemia).
ZanubrutinibA kinase inhibitor used to treat mantle cell lymphoma, a type of B-cell non-Hodgkin lymphoma, in adults who previously received therapy.
VoruciclibVoruciclib is under investigation in clinical trial NCT03547115 (A Phase 1 Study of Voruciclib in Subjects With B-Cell Malignancies or AML).
KRN-5500KRN-5500 is under investigation in clinical trial NCT00002923 (KRN5500 in Treating Patients With Metastatic Solid Tumors).
SOR-C13SOR-C13 is under investigation in clinical trial NCT01578564 (Safety and Tolerability Study of SOR-C13 in Subjects With Advanced Cancers Commonly Known to Express the TRPV6 Channel).
TallimustineAn alkylating agent previously investigated for it's antitumor activity but was stopped due to severe myelotoxicity.
PexidartinibAn antitumor agent that is used for the treatment of rare disease tenosynovial giant cell tumors (TGCT) by inhibiting colony-stimulating factor 1 and its receptor.
CinnamaldehydeCinnamaldehyde is approved by the FDA for use within allergenic epicutaneous patch tests which are indicated for use as an aid in the diagnosis of allergic contact dermatitis (ACD) in...
EntrectinibEntrectinib is indicated for the treatment of metastatic ROS1-positive non-small cell lung cancer in adults. Entrectinib is also indicated in adults and children over 12 years old for the treatment...
LarotrectinibA kinase inhibitor used to treat solid tumors with neurotrophic receptor tyrosine kinase gene fusion, are metastatic, high risk for surgery, or have no alternative treatments.
AcalabrutinibA Bruton tyrosine kinase inhibitor used to treat mantle cell lymphoma, chronic lymphocytic leukemia, and small lymphocytic lymphoma.
4-(dimethylamino)-N-[7-(hydroxyamino)-7-oxoheptyl]benzamideNot Available
N-hydroxyguanidineNot Available
PadeliporfinNot Annotated
EchinomycinEchinomycin is a cytotoxic polypeptide quinoxaline antibiotic isolated from Streptomyces echinatus that binds to DNA and inhibits RNA synthesis.
Ursolic acidNot Annotated
VolasertibVolasertib has been used in trials studying the treatment of Leukemia, Neoplasms, Leukemia, Myeloid, Acute, Myelodysplastic Syndromes, and Leukemia, Monocytic, Acute, among others.
MIV-711Not Annotated
Axicabtagene ciloleucelA CAR T cell therapy for relapsed or refractory large B-cell lymphoma, diffuse large B-cell lymphoma, primary mediastinal large B-cell lymphoma, high grade B-cell lymphoma, and diffuse large B-cell lymphoma from follicular lymphoma.
BropirimineNot Available
LexacalcitolLexacalcitol is a solid. This compound belongs to the vitamin D and derivatives class of chemicals. These are compounds containing a secosteroid backbone, usually secoergostane or secocholestane. It is known...
DeacetoxyvinzolidineNot Available
Trichostatin ANot Available
alpha,beta-Methyleneadenosine 5'-triphosphateNot Available
5'-S-methyl-5'-thioadenosineNot Available
Sodium phosphate P 32Not Annotated
Edodekin alfaEdodekin alfa is under investigation in clinical trial NCT01468896 (Cetuximab and Recombinant Interleukin-12 in Treating Patients With Squamous Cell Carcinoma of the Head and Neck That Is Recurrent, Metastatic, or...
AMG-337AMG-337 is under investigation in clinical trial NCT03147976 (QUILT-3.036: AMG 337 in Subjects With Advanced or Metastatic Solid Tumors).
IsatuximabA chimeric monoclonal antibody targeted against surface CD38 glycoproteins for the treatment of multiple myeloma in patients who have failed previous therapies.
DroloxifeneNot Annotated
PemigatinibA kinase inhibitor used to treat locally advanced or metastatic, unresectable cholangiocarcinoma in previously treated adult patients.
DarolutamideAn androgen receptor antagonist used for castration-resistant, non-metastatic prostate cancer.
CapmatinibA kinase inhibitor targeting c-Met receptor tyrosine kinase in the treatment of non-small cell lung cancer with MET exon 14 skipping.
SelpercatinibA RET receptor tyrosine kinase inhibitor for the treatment of RET-driven non-small cell lung cancer, medullary thyroid cancer, and thyroid cancer in appropriate patient populations.
Incadronic acidIncadronate has been investigated in the treatment of myeloma,[A14426,A14431] leukemia, and other cancers. It has also been investigated in patients with hypercalcemia of malignancy.
Talactoferrin alfaInvestigated for use/treatment in adverse effects (chemotherapy), cancer/tumors (unspecified), diabetic foot ulcers, lung cancer, solid tumors, and ulcers.
Brexucabtagene autoleucelA modified autologous chimeric antigen receptor (CAR) T cell therapy employing a modified murine anti-CD19 single-chain variable fragment linked to CD28 and CD3ζ co-stimulatory domains for the treatment of patients with relapsed and refractory mantle cell lymphoma.
SelinexorSelinexor is indicated for the treatment of relapsed or refractory multiple myeloma in combination with dexamethasone.[label] Patients must have received at least 4 prior therapies and have disease which is...
FedratinibFedratinib is indicated to treat adults with primary or secondary myelofibrosis that is either intermediate-2 or high risk.
QuizartinibQuizartinib is under investigation in Childhood Acute Myeloid Leukemia/Other Myeloid Malignancies. It is a potent inhibitor of FLT3.
PralsetinibA RET receptor tyrosine kinase inhibitor for the treatment of metastatic RET-driven non-small cell lung cancer.
TucatinibA kinase inhibitor used to treat certain types of unresectable/metastatic HER-2 positive breast cancer.
Drugs & Drug Targets
DrugTargetType
CetuximabEpidermal growth factor receptortarget
CetuximabLow affinity immunoglobulin gamma Fc region receptor III-Btarget
CetuximabComplement C1q subcomponent subunit Atarget
CetuximabComplement C1q subcomponent subunit Btarget
CetuximabComplement C1q subcomponent subunit Ctarget
CetuximabLow affinity immunoglobulin gamma Fc region receptor III-Atarget
CetuximabHigh affinity immunoglobulin gamma Fc receptor Itarget
CetuximabLow affinity immunoglobulin gamma Fc region receptor II-atarget
Denileukin diftitoxInterleukin-2 receptor subunit alphatarget
Denileukin diftitoxCytokine receptor common subunit gammatarget
Denileukin diftitoxInterleukin-2 receptor subunit betatarget
Asparaginase Escherichia coliL-asparaginetarget
Asparaginase Escherichia coliThyroxine-binding globulincarrier
PegaspargaseL-asparaginetarget
PegaspargaseThyroxine-binding globulincarrier
TrastuzumabReceptor tyrosine-protein kinase erbB-2target
RituximabB-lymphocyte antigen CD20target
BevacizumabVascular endothelial growth factor Atarget
BevacizumabComplement C1q subcomponent subunit Atarget
BevacizumabComplement C1q subcomponent subunit Btarget
BevacizumabComplement C1q subcomponent subunit Ctarget
BevacizumabLow affinity immunoglobulin gamma Fc region receptor III-Atarget
BevacizumabLow affinity immunoglobulin gamma Fc region receptor II-atarget
BevacizumabLow affinity immunoglobulin gamma Fc region receptor II-btarget
BevacizumabLow affinity immunoglobulin gamma Fc region receptor II-ctarget
BevacizumabHigh affinity immunoglobulin gamma Fc receptor Itarget
BortezomibCytochrome P450 3A4enzyme
BortezomibCytochrome P450 2C19enzyme
BortezomibCytochrome P450 1A2enzyme
BortezomibCytochrome P450 2D6enzyme
BortezomibCytochrome P450 2C9enzyme
BortezomibProteasome subunit beta type-5target
BortezomibProteasome subunit beta type-1target
BortezomibP-glycoprotein 1transporter
BortezomibSolute carrier organic anion transporter family member 1B3transporter
PipobromanDNAtarget
CladribinePurine nucleoside phosphorylasetarget
CladribineDNAtarget
CladribineDeoxycytidine kinaseenzyme
CladribineRibonucleoside-diphosphate reductase large subunittarget
CladribineRibonucleoside-diphosphate reductase subunit M2target
CladribineRibonucleoside-diphosphate reductase subunit M2 Btarget
CladribineDNA polymerase alpha catalytic subunittarget
CladribineDNA polymerase epsilon catalytic subunit Atarget
CladribineDNA polymerase epsilon subunit 2target
CladribineDNA polymerase epsilon subunit 3target
CladribineDNA polymerase epsilon subunit 4target
CladribineATP-binding cassette sub-family G member 2transporter
CladribineSolute carrier family 28 member 3transporter
CarmustineGlutathione reductase, mitochondrialtarget
CarmustineDNAtarget
CarmustineRNAtarget
AmsacrineDNA topoisomerase 2-alphatarget
AmsacrineDNAtarget
AmsacrinePotassium voltage-gated channel subfamily H member 2target
AmsacrineP-glycoprotein 1transporter
AmsacrineAlpha-1-acid glycoprotein 1target
AmsacrineSerum albumintarget
BleomycinDNA ligase 3target
BleomycinDNA ligase 1target
BleomycinDNAtarget
BleomycinBleomycin hydrolaseenzyme
ChlorambucilDNAtarget
ChlorambucilGlutathione S-transferase Penzyme
ChlorambucilSolute carrier organic anion transporter family member 1A2transporter
RaltitrexedThymidylate synthasetarget
RaltitrexedFolylpolyglutamate synthase, mitochondrialtarget
MitomycinDNAtarget
MitomycinNADPH--cytochrome P450 reductaseenzyme
BexaroteneRetinoic acid receptor RXR-betatarget
BexaroteneCytochrome P450 3A4enzyme
BexaroteneRetinoic acid receptor RXR-alphatarget
BexaroteneRetinoic acid receptor RXR-gammatarget
BexaroteneCytochrome P450 2C8enzyme
VindesineTubulin beta-1 chaintarget
VindesineCytochrome P450 3A4enzyme
GefitinibEpidermal growth factor receptortarget
GefitinibCytochrome P450 3A4enzyme
GefitinibCytochrome P450 2D6enzyme
GefitinibP-glycoprotein 1transporter
GefitinibATP-binding cassette sub-family G member 2transporter
GefitinibCytochrome P450 3A5enzyme
GefitinibCytochrome P450 1A1enzyme
GefitinibCytochrome P450 2C9enzyme
GefitinibCytochrome P450 2C19enzyme
GefitinibSerum albumincarrier
GefitinibAlpha-1-acid glycoprotein 1carrier
TioguanineDNAtarget
TioguanineMultidrug resistance-associated protein 4transporter
TioguanineHypoxanthine-guanine phosphoribosyltransferaseenzyme
VinorelbineTubulin beta chaintarget
VinorelbineCytochrome P450 3A4enzyme
VinorelbineCytochrome P450 2D6enzyme
ValrubicinDNA topoisomerase 2-alphatarget
ValrubicinDNAtarget
SorafenibSerine/threonine-protein kinase B-raftarget
SorafenibReceptor-type tyrosine-protein kinase FLT3target
SorafenibRAF proto-oncogene serine/threonine-protein kinasetarget
SorafenibVascular endothelial growth factor receptor 3target
SorafenibPlatelet-derived growth factor receptor betatarget
SorafenibMast/stem cell growth factor receptor Kittarget
SorafenibVascular endothelial growth factor receptor 2target
SorafenibCytochrome P450 3A4enzyme
SorafenibUDP-glucuronosyltransferase 1-9enzyme
SorafenibCytochrome P450 2B6enzyme
SorafenibCytochrome P450 2C8enzyme
SorafenibCytochrome P450 3A5enzyme
SorafenibCytochrome P450 3A7enzyme
SorafenibCytochrome P450 2C9enzyme
SorafenibMultidrug resistance-associated protein 4transporter
SorafenibP-glycoprotein 1transporter
SorafenibCanalicular multispecific organic anion transporter 1transporter
SorafenibATP-binding cassette sub-family G member 2transporter
SorafenibCytochrome P450 1A2enzyme
SorafenibCytochrome P450 2C19enzyme
SorafenibCytochrome P450 2D6enzyme
SorafenibUDP-glucuronosyltransferase 1-1enzyme
SorafenibRalA-binding protein 1transporter
SorafenibFibroblast growth factor receptor 1target
SorafenibProto-oncogene tyrosine-protein kinase receptor Rettarget
SorafenibVascular endothelial growth factor receptor 1target
SorafenibSolute carrier organic anion transporter family member 1B1transporter
StreptozocinDNAtarget
StreptozocinP-glycoprotein 1transporter
StreptozocinSolute carrier family 2, facilitated glucose transporter member 2target
StreptozocinO-GlcNAcase BT_4395target
StreptozocinCytochrome P450 1A1enzyme
StreptozocinCytochrome P450 1A2enzyme
StreptozocinCytochrome P450 2E1enzyme
StreptozocinBifunctional protein NCOATtarget
GemcitabineRibonucleoside-diphosphate reductase large subunittarget
GemcitabineUMP-CMP kinasetarget
GemcitabineThymidylate synthasetarget
GemcitabineCytidine deaminaseenzyme
GemcitabineDeoxycytidine kinaseenzyme
GemcitabineP-glycoprotein 1transporter
GemcitabineMultidrug resistance-associated protein 7transporter
GemcitabineEquilibrative nucleoside transporter 1transporter
GemcitabineDNAtarget
GemcitabineSodium/nucleoside cotransporter 1transporter
GemcitabineEquilibrative nucleoside transporter 2transporter
GemcitabineSolute carrier family 28 member 3transporter
TeniposideDNA topoisomerase 2-alphatarget
TeniposideCytochrome P450 2C19enzyme
TeniposideCytochrome P450 2C9enzyme
TeniposideCytochrome P450 3A4enzyme
TeniposideMultidrug resistance-associated protein 6transporter
TeniposideATP-binding cassette sub-family G member 2transporter
TeniposideCytochrome P450 3A5enzyme
EpirubicinDNA topoisomerase 2-alphatarget
EpirubicinDNAtarget
EpirubicinMultidrug resistance-associated protein 1transporter
EpirubicinUDP-glucuronosyltransferase 2B7enzyme
EpirubicinCytosolic phospholipase A2enzyme
AltretamineDNAtarget
CisplatinDNAtarget
CisplatinCanalicular multispecific organic anion transporter 2transporter
CisplatinMultidrug resistance-associated protein 5transporter
CisplatinCanalicular multispecific organic anion transporter 1transporter
CisplatinSolute carrier family 22 member 2transporter
CisplatinHigh affinity copper uptake protein 1transporter
CisplatinProbable low affinity copper uptake protein 2transporter
CisplatinMultidrug resistance-associated protein 6transporter
CisplatinP-glycoprotein 1transporter
CisplatinCopper-transporting ATPase 2transporter
CisplatinCopper-transporting ATPase 1transporter
CisplatinProstaglandin G/H synthase 2enzyme
CisplatinMyeloperoxidaseenzyme
CisplatinXanthine dehydrogenase/oxidaseenzyme
CisplatinArylamine N-acetyltransferaseenzyme
CisplatinCytochrome P450 2C9enzyme
CisplatinCytochrome P450 2B6enzyme
CisplatinCholinesteraseenzyme
CisplatinCytochrome P450 4A11enzyme
CisplatinATP-binding cassette sub-family G member 2transporter
CisplatinGlutathione S-transferase theta-1enzyme
CisplatinMetallothionein-1Aenzyme
CisplatinMetallothionein-2enzyme
CisplatinSuperoxide dismutase [Cu-Zn]enzyme
CisplatinGlutathione S-transferase Penzyme
CisplatinNAD(P)H dehydrogenase [quinone] 1enzyme
CisplatinGlutathione S-transferase Mu 1enzyme
CisplatinDNA-3-methyladenine glycosylasetarget
CisplatinAlpha-2-macroglobulintarget
CisplatinSerum albumincarrier
CisplatinSerotransferrintarget
CisplatinCopper transport protein ATOX1target
AlitretinoinRetinoic acid receptor alphatarget
AlitretinoinRetinoic acid receptor RXR-betatarget
AlitretinoinRetinoic acid receptor gammatarget
AlitretinoinRetinoic acid receptor betatarget
AlitretinoinRetinoic acid receptor RXR-gammatarget
AlitretinoinRetinoic acid receptor RXR-alphatarget
AlitretinoinCellular retinoic acid-binding protein 2carrier
AlitretinoinCellular retinoic acid-binding protein 1carrier
AlitretinoinP-glycoprotein 1transporter
AlitretinoinInsulin-like growth factor-binding protein 3target
AlitretinoinPregnancy-specific beta-1-glycoprotein 5target
AlitretinoinCytochrome P450 26C1target
OxaliplatinDNAtarget
OxaliplatinSolute carrier family 22 member 2transporter
OxaliplatinHigh affinity copper uptake protein 1transporter
OxaliplatinSolute carrier family 22 member 3transporter
OxaliplatinATP-binding cassette sub-family G member 2transporter
OxaliplatinGlutathione S-transferase theta-1enzyme
OxaliplatinMetallothionein-1Aenzyme
OxaliplatinMetallothionein-2enzyme
OxaliplatinMyeloperoxidaseenzyme
OxaliplatinSuperoxide dismutase [Cu-Zn]enzyme
OxaliplatinGlutathione S-transferase Penzyme
OxaliplatinGlutathione S-transferase Mu 1enzyme
OxaliplatinNAD(P)H dehydrogenase [quinone] 1enzyme
OxaliplatinCanalicular multispecific organic anion transporter 1transporter
OxaliplatinCopper-transporting ATPase 2transporter
OxaliplatinCopper-transporting ATPase 1transporter
ErlotinibEpidermal growth factor receptortarget
ErlotinibCytochrome P450 3A4enzyme
ErlotinibATP-binding cassette sub-family G member 2transporter
ErlotinibP-glycoprotein 1transporter
ErlotinibNuclear receptor subfamily 1 group I member 2target
ErlotinibCytochrome P450 3A5enzyme
ErlotinibCytochrome P450 1A1enzyme
ErlotinibCytochrome P450 1A2enzyme
ErlotinibCytochrome P450 1B1enzyme
ErlotinibCytochrome P450 2D6enzyme
ErlotinibCytochrome P450 2C8enzyme
ErlotinibUDP-glucuronosyltransferase 1-1enzyme
ErlotinibSerum albumincarrier
ErlotinibAlpha-1-acid glycoprotein 1carrier
ErlotinibSolute carrier organic anion transporter family member 2B1transporter
CyclophosphamideDNAtarget
CyclophosphamideCytochrome P450 2B6enzyme
CyclophosphamideCytochrome P450 2C9enzyme
CyclophosphamideCytochrome P450 3A4enzyme
CyclophosphamideCytochrome P450 2C19enzyme
CyclophosphamideCytochrome P450 2A6enzyme
CyclophosphamideCytochrome P450 2C18enzyme
CyclophosphamideCytochrome P450 2C8enzyme
CyclophosphamideCytochrome P450 3A5enzyme
CyclophosphamideNuclear receptor subfamily 1 group I member 2target
VincristineTubulin beta chaintarget
VincristineCytochrome P450 3A4enzyme
VincristineCytochrome P450 3A5enzyme
VincristineCytochrome P450 3A7enzyme
VincristineP-glycoprotein 1transporter
VincristineCanalicular multispecific organic anion transporter 2transporter
VincristineSolute carrier family 22 member 3transporter
VincristineMultidrug resistance-associated protein 1transporter
VincristineMultidrug resistance-associated protein 7transporter
VincristineCanalicular multispecific organic anion transporter 1transporter
VincristineBile salt export pumptransporter
VincristineATP-binding cassette sub-family G member 2transporter
VincristineTubulin alpha-4A chaintarget
VincristineRalA-binding protein 1transporter
VincristineSolute carrier organic anion transporter family member 1B1transporter
VincristineSolute carrier organic anion transporter family member 1B3transporter
FluorouracilThymidylate synthasetarget
FluorouracilCytochrome P450 1A2enzyme
FluorouracilThymidine phosphorylaseenzyme
FluorouracilSerum albumincarrier
FluorouracilCytochrome P450 2C9enzyme
FluorouracilDihydropyrimidine dehydrogenase [NADP(+)]enzyme
FluorouracilUridine phosphorylase 1enzyme
FluorouracilUridine phosphorylase 2enzyme
FluorouracilDNAtarget
FluorouracilRNAtarget
FluorouracilCytochrome P450 2A6enzyme
FluorouracilCytochrome P450 2C8enzyme
FluorouracilMethylenetetrahydrofolate reductaseenzyme
FluorouracilThymidylate synthaseenzyme
FluorouracilUridine 5'-monophosphate synthaseenzyme
FluorouracilAmidophosphoribosyltransferaseenzyme
FluorouracilSolute carrier family 22 member 7transporter
FluorouracilEquilibrative nucleoside transporter 1transporter
FluorouracilATP-binding cassette sub-family G member 2transporter
FluorouracilCanalicular multispecific organic anion transporter 2transporter
FluorouracilMultidrug resistance-associated protein 4transporter
FluorouracilMultidrug resistance-associated protein 5transporter
FluorouracilThyroxine-binding globulincarrier
PentostatinAdenosine deaminasetarget
MethotrexateDihydrofolate reductasetarget
MethotrexateAldehyde oxidaseenzyme
MethotrexateMethylenetetrahydrofolate reductaseenzyme
MethotrexateSerum albumincarrier
MethotrexateCanalicular multispecific organic anion transporter 2transporter
MethotrexateMultidrug resistance-associated protein 4transporter
MethotrexateMultidrug resistance-associated protein 1transporter
MethotrexateSolute carrier family 22 member 6transporter
MethotrexateMultidrug resistance-associated protein 7transporter
MethotrexateSolute carrier family 22 member 8transporter
MethotrexateCanalicular multispecific organic anion transporter 1transporter
MethotrexateP-glycoprotein 1transporter
MethotrexateSolute carrier organic anion transporter family member 1A2transporter
MethotrexateMonocarboxylate transporter 1transporter
MethotrexateATP-binding cassette sub-family C member 11transporter
MethotrexateSolute carrier organic anion transporter family member 1B3transporter
MethotrexateSolute carrier family 22 member 11transporter
MethotrexateSolute carrier organic anion transporter family member 1C1transporter
MethotrexateSolute carrier organic anion transporter family member 3A1transporter
MethotrexateATP-binding cassette sub-family G member 2transporter
MethotrexateSolute carrier family 22 member 7transporter
MethotrexateSolute carrier organic anion transporter family member 1B1transporter
Methotrexate6-phosphogluconate dehydrogenase, decarboxylatingenzyme
MethotrexateProton-coupled folate transportertransporter
MethotrexateFolylpolyglutamate synthase, mitochondrialenzyme
MethotrexateGamma-glutamyl hydrolaseenzyme
MethotrexateDihydrofolate reductaseenzyme
MethotrexateThymidylate synthaseenzyme
MethotrexateBifunctional purine biosynthesis protein PURHenzyme
MethotrexateSolute carrier organic anion transporter family member 4C1transporter
MethotrexateFolate transporter 1transporter
MethotrexateFolate receptor alphatransporter
MethotrexateCytochrome P450 3A4enzyme
MethotrexateThymidylate synthasetarget
MethotrexateBifunctional purine biosynthesis protein PURHtarget
MethotrexateFolate receptor betatransporter
MethotrexateSolute carrier family 15 member 1transporter
MethotrexateProton-coupled amino acid transporter 1transporter
VinblastineTubulin beta chaintarget
VinblastineTranscription factor AP-1target
VinblastineCytochrome P450 3A4enzyme
VinblastineP-glycoprotein 1transporter
VinblastineMultidrug resistance-associated protein 1transporter
VinblastineCanalicular multispecific organic anion transporter 1transporter
VinblastineMultidrug resistance-associated protein 6transporter
VinblastineBile salt export pumptransporter
VinblastineTubulin alpha-1A chaintarget
VinblastineTubulin delta chaintarget
VinblastineTubulin epsilon chaintarget
VinblastineTubulin gamma-1 chaintarget
VinblastineCytochrome P450 2D6enzyme
VinblastineSolute carrier organic anion transporter family member 1B1transporter
ImatinibPlatelet-derived growth factor receptor betatarget
ImatinibTyrosine-protein kinase ABL1target
ImatinibMast/stem cell growth factor receptor Kittarget
ImatinibRET proto-oncogenetarget
ImatinibHigh affinity nerve growth factor receptortarget
ImatinibMacrophage colony-stimulating factor 1 receptortarget
ImatinibPlatelet-derived growth factor receptor alphatarget
ImatinibEpithelial discoidin domain-containing receptor 1target
ImatinibCytochrome P450 3A4enzyme
ImatinibBreakpoint cluster region proteintarget
ImatinibCytochrome P450 1A2enzyme
ImatinibCytochrome P450 2D6enzyme
ImatinibCytochrome P450 2C9enzyme
ImatinibCytochrome P450 2C19enzyme
ImatinibCytochrome P450 3A5enzyme
ImatinibCytochrome P450 3A7enzyme
ImatinibSolute carrier family 22 member 1transporter
ImatinibP-glycoprotein 1transporter
ImatinibSolute carrier family 22 member 2transporter
ImatinibATP-binding cassette sub-family G member 2transporter
ImatinibATP-binding cassette sub-family A member 3transporter
ImatinibProstaglandin G/H synthase 1enzyme
ImatinibSerum albumincarrier
ImatinibAlpha-1-acid glycoprotein 1carrier
ImatinibBile salt export pumptransporter
ImatinibCytochrome P450 2C8enzyme
ClofarabineDNA polymerase alpha catalytic subunittarget
ClofarabineRibonucleoside-diphosphate reductase large subunittarget
ClofarabineDeoxycytidine kinaseenzyme
ClofarabineDNAtarget
ClofarabineATP-binding cassette sub-family G member 2transporter
PemetrexedThymidylate synthasetarget
PemetrexedDihydrofolate reductasetarget
PemetrexedTrifunctional purine biosynthetic protein adenosine-3target
PemetrexedDeoxycytidine kinaseenzyme
PemetrexedBifunctional purine biosynthesis protein PURHtarget
PemetrexedEquilibrative nucleoside transporter 1enzyme
PemetrexedSolute carrier family 22 member 8transporter
MitotaneCytochrome P450 11B1, mitochondrialtarget
MitotaneAdrenodoxin, mitochondrialtarget
MitotaneSex hormone-binding globulincarrier
MitotaneCorticosteroid-binding globulincarrier
MitotaneCytochrome P450 3A4enzyme
MitotaneEstrogen receptor alphatarget
MitotaneProgesterone receptortarget
MitotaneAndrogen receptortarget
MitotaneThyroxine-binding globulincarrier
MitotaneP-glycoprotein 1transporter
DaunorubicinDNAtarget
DaunorubicinXanthine dehydrogenase/oxidaseenzyme
DaunorubicinCytochrome P450 3A5enzyme
DaunorubicinNADPH--cytochrome P450 reductaseenzyme
DaunorubicinP-glycoprotein 1transporter
DaunorubicinMultidrug resistance-associated protein 1transporter
DaunorubicinCanalicular multispecific organic anion transporter 1transporter
DaunorubicinMultidrug resistance-associated protein 6transporter
DaunorubicinBile salt export pumptransporter
DaunorubicinMultidrug resistance-associated protein 7transporter
DaunorubicinATP-binding cassette sub-family G member 2transporter
DaunorubicinDNA topoisomerase 2-alphatarget
DaunorubicinDNA topoisomerase 2-betatarget
DaunorubicinCytochrome P450 1A1enzyme
DaunorubicinCytochrome P450 1B1enzyme
DaunorubicinCytochrome P450 3A4enzyme
Porfimer sodiumLow-density lipoprotein receptortarget
Porfimer sodiumHigh affinity immunoglobulin gamma Fc receptor Itarget
IrinotecanDNA topoisomerase I, mitochondrialtarget
IrinotecanDNA topoisomerase 1target
IrinotecanCytochrome P450 3A4enzyme
IrinotecanCytochrome P450 3A5enzyme
IrinotecanUDP-glucuronosyltransferase 1-1enzyme
IrinotecanUDP-glucuronosyltransferase 1-9enzyme
IrinotecanLiver carboxylesterase 1enzyme
IrinotecanCytochrome P450 3A7enzyme
IrinotecanCytochrome P450 2B6enzyme
IrinotecanSolute carrier family 22 member 3transporter
IrinotecanSolute carrier organic anion transporter family member 1B1transporter
IrinotecanMultidrug resistance-associated protein 1transporter
IrinotecanATP-binding cassette sub-family G member 2transporter
IrinotecanSerum albumincarrier
IrinotecanCocaine esteraseenzyme
IrinotecanCholinesteraseenzyme
IrinotecanP-glycoprotein 1transporter
IrinotecanCanalicular multispecific organic anion transporter 1transporter
EtoposideDNA topoisomerase 2-alphatarget
EtoposideCytochrome P450 3A4enzyme
EtoposideCanalicular multispecific organic anion transporter 2transporter
EtoposideMultidrug resistance-associated protein 6transporter
EtoposideP-glycoprotein 1transporter
EtoposideMultidrug resistance-associated protein 1transporter
EtoposideMultidrug resistance-associated protein 7transporter
EtoposideCanalicular multispecific organic anion transporter 1transporter
EtoposideATP-binding cassette sub-family G member 2transporter
EtoposideCytochrome P450 1A2enzyme
EtoposideCytochrome P450 2E1enzyme
EtoposideCytochrome P450 3A5enzyme
EtoposideUDP-glucuronosyltransferase 1-1enzyme
EtoposideDNA topoisomerase 2-betatarget
EtoposideGlutathione S-transferase theta-1enzyme
EtoposideGlutathione S-transferase Penzyme
EtoposideProstaglandin G/H synthase 2enzyme
EtoposideProstaglandin G/H synthase 1enzyme
DacarbazineDNA polymerase alpha subunit Btarget
DacarbazineCytochrome P450 1A1enzyme
DacarbazineCytochrome P450 1A2enzyme
DacarbazineCytochrome P450 2E1enzyme
Dacarbazine6-phosphogluconate dehydrogenase, decarboxylatingtarget
DacarbazineDNAtarget
TemozolomideDNAtarget
MechlorethamineDNAtarget
MechlorethamineCholinesteraseenzyme
AzacitidineDNA (cytosine-5)-methyltransferase 1target
AzacitidineCytidine deaminaseenzyme
AzacitidineDNAtarget
AzacitidineRNAtarget
CarboplatinDNAtarget
CarboplatinHigh affinity copper uptake protein 1transporter
CarboplatinProbable low affinity copper uptake protein 2transporter
CarboplatinXanthine dehydrogenase/oxidaseenzyme
CarboplatinMyeloperoxidaseenzyme
CarboplatinGlutathione S-transferase theta-1enzyme
CarboplatinMetallothionein-1Aenzyme
CarboplatinMetallothionein-2enzyme
CarboplatinSuperoxide dismutase [Cu-Zn]enzyme
CarboplatinGlutathione S-transferase Penzyme
CarboplatinGlutathione S-transferase Mu 1enzyme
CarboplatinNAD(P)H dehydrogenase [quinone] 1enzyme
CarboplatinCopper-transporting ATPase 1transporter
CarboplatinCopper-transporting ATPase 2transporter
CarboplatinATP-binding cassette sub-family G member 2transporter
CarboplatinCanalicular multispecific organic anion transporter 1transporter
DactinomycinDNAtarget
DactinomycinSolute carrier family 22 member 5transporter
DactinomycinP-glycoprotein 1transporter
DactinomycinMultidrug resistance-associated protein 6transporter
DactinomycinMultidrug resistance-associated protein 1transporter
DactinomycinATP-binding cassette sub-family G member 2transporter
DactinomycinDNA topoisomerase 2target
CytarabineDNA polymerase betatarget
CytarabineCytidine deaminaseenzyme
CytarabineSolute carrier family 22 member 4transporter
CytarabineMultidrug resistance-associated protein 7transporter
CytarabineEquilibrative nucleoside transporter 1transporter
CytarabineDNAtarget
CytarabineCytochrome P450 3A4enzyme
CytarabineDeoxycytidine kinaseenzyme
Cytarabine5'-nucleotidaseenzyme
CytarabineDeoxycytidylate deaminaseenzyme
DoxorubicinDNA topoisomerase 2-alphatarget
DoxorubicinDNAtarget
DoxorubicinCytochrome P450 3A4enzyme
DoxorubicinCytochrome P450 2D6enzyme
DoxorubicinCytochrome P450 2B6enzyme
DoxorubicinP-glycoprotein 1transporter
DoxorubicinCanalicular multispecific organic anion transporter 2transporter
DoxorubicinMultidrug resistance-associated protein 6transporter
DoxorubicinMultidrug resistance-associated protein 1transporter
DoxorubicinMultidrug resistance-associated protein 7transporter
DoxorubicinATP-binding cassette sub-family G member 2transporter
DoxorubicinBile salt export pumptransporter
DoxorubicinSolute carrier family 22 member 16transporter
DoxorubicinATP-binding cassette sub-family B member 8, mitochondrialtransporter
DoxorubicinCytochrome P450 1B1enzyme
DoxorubicinCarbonyl reductase [NADPH] 1enzyme
DoxorubicinCarbonyl reductase [NADPH] 3enzyme
DoxorubicinAlcohol dehydrogenase [NADP(+)]enzyme
DoxorubicinAldo-keto reductase family 1 member C3enzyme
DoxorubicinNAD(P)H dehydrogenase [quinone] 1enzyme
DoxorubicinXanthine dehydrogenase/oxidaseenzyme
DoxorubicinNitric oxide synthase, endothelialenzyme
DoxorubicinNitric oxide synthase, inducibleenzyme
DoxorubicinNitric oxide synthase, brainenzyme
DoxorubicinNADH dehydrogenase [ubiquinone] iron-sulfur protein 2, mitochondrialenzyme
DoxorubicinNADH dehydrogenase [ubiquinone] iron-sulfur protein 3, mitochondrialenzyme
DoxorubicinNADH dehydrogenase [ubiquinone] iron-sulfur protein 7, mitochondrialenzyme
DoxorubicinNADPH--cytochrome P450 reductaseenzyme
DoxorubicinRalA-binding protein 1transporter
DoxorubicinCanalicular multispecific organic anion transporter 1transporter
DoxorubicinSerum albumincarrier
DoxorubicinNucleolar and coiled-body phosphoprotein 1target
HydroxyureaRibonucleoside-diphosphate reductase large subunittarget
HydroxyureaCytochrome P450 2D6enzyme
BusulfanDNAtarget
BusulfanCytochrome P450 3A4enzyme
BusulfanGlutathione S-transferase A2enzyme
BusulfanGlutathione S-transferase A1enzyme
BusulfanGlutathione S-transferase Mu 1enzyme
BusulfanGlutathione S-transferase Penzyme
BusulfanMicrosomal glutathione S-transferase 2enzyme
TopotecanDNA topoisomerase I, mitochondrialtarget
TopotecanDNA topoisomerase 1target
TopotecanATP-binding cassette sub-family G member 2transporter
TopotecanP-glycoprotein 1transporter
TopotecanCytochrome P450 3A4enzyme
TopotecanDNAtarget
TopotecanMultidrug and toxin extrusion protein 1transporter
TopotecanMultidrug and toxin extrusion protein 2transporter
MercaptopurineThiopurine S-methyltransferaseenzyme
MercaptopurineXanthine dehydrogenase/oxidaseenzyme
MercaptopurineHypoxanthine-guanine phosphoribosyltransferasetarget
MercaptopurineSolute carrier family 22 member 8transporter
MercaptopurineMultidrug resistance-associated protein 4transporter
MercaptopurineMultidrug resistance-associated protein 5transporter
MercaptopurineSodium/nucleoside cotransporter 2transporter
MercaptopurineSolute carrier family 28 member 3transporter
MercaptopurineEquilibrative nucleoside transporter 1transporter
MercaptopurineEquilibrative nucleoside transporter 2transporter
MercaptopurineAldehyde oxidaseenzyme
MercaptopurineAmidophosphoribosyltransferasetarget
MercaptopurineInosine-5'-monophosphate dehydrogenasetarget
MelphalanDNAtarget
MelphalanSolute carrier family 22 member 3transporter
MelphalanLarge neutral amino acids transporter small subunit 1transporter
FludarabineDNA polymerase alpha catalytic subunittarget
FludarabineRibonucleoside-diphosphate reductase large subunittarget
FludarabineEquilibrative nucleoside transporter 1transporter
FludarabineDNAtarget
FludarabineDeoxycytidine kinasetarget
FludarabineSolute carrier family 28 member 3transporter
CapecitabineThymidylate synthasetarget
CapecitabineThymidine phosphorylaseenzyme
CapecitabineCytidine deaminaseenzyme
CapecitabineLiver carboxylesterase 1enzyme
CapecitabineDihydropyrimidine dehydrogenase [NADP(+)]enzyme
CapecitabineCytochrome P450 2C9enzyme
CapecitabineDNAtarget
CapecitabineRNAtarget
ProcarbazineDNAtarget
ProcarbazineXanthine dehydrogenase/oxidaseenzyme
ProcarbazineMonoamine oxidasetarget
Arsenic trioxideInhibitor of nuclear factor kappa-B kinase subunit betatarget
Arsenic trioxideTranscription factor AP-1target
Arsenic trioxideG1/S-specific cyclin-D1target
Arsenic trioxideMitogen-activated protein kinase 3target
Arsenic trioxideMitogen-activated protein kinase 1target
Arsenic trioxideRAC-alpha serine/threonine-protein kinasetarget
Arsenic trioxideCanalicular multispecific organic anion transporter 1transporter
Arsenic trioxideThioredoxin reductase 1, cytoplasmictarget
Arsenic trioxideP-glycoprotein 1transporter
Arsenic trioxideCytochrome P450 3A4enzyme
Arsenic trioxideCyclin-dependent kinase inhibitor 1target
Arsenic trioxideHistone deacetylase 1target
Arsenic trioxideProtein PMLtarget
Arsenic trioxideSerum albumincarrier
IdarubicinDNA topoisomerase 2-alphatarget
IdarubicinDNAtarget
IdarubicinMultidrug resistance-associated protein 1transporter
IdarubicinCytochrome P450 2C9enzyme
IdarubicinCytochrome P450 2D6enzyme
IfosfamideCytochrome P450 2B6enzyme
IfosfamideDNAtarget
IfosfamideCytochrome P450 3A4enzyme
IfosfamideCytochrome P450 3A5enzyme
IfosfamideCytochrome P450 2C9enzyme
IfosfamideCytochrome P450 2C8enzyme
IfosfamideCytochrome P450 2A6enzyme
IfosfamideCytochrome P450 2C19enzyme
IfosfamideCytochrome P450 2C18enzyme
IfosfamideProstaglandin G/H synthase 1enzyme
IfosfamideNuclear receptor subfamily 1 group I member 2target
EstramustineEstrogen receptor betatarget
EstramustineEstrogen receptor alphatarget
EstramustineMicrotubule-associated protein 2target
EstramustineMicrotubule-associated protein 1Atarget
EstramustineP-glycoprotein 1transporter
EstramustineCytochrome P450 3A4enzyme
MitoxantroneDNA topoisomerase 2-alphatarget
MitoxantroneCytochrome P450 2E1enzyme
MitoxantroneP-glycoprotein 1transporter
MitoxantroneMultidrug resistance-associated protein 1transporter
MitoxantroneATP-binding cassette sub-family G member 2transporter
MitoxantroneDNAtarget
MitoxantroneCytochrome P450 1B1enzyme
MitoxantroneCytochrome P450 3A4enzyme
LomustineDNAtarget
LomustineCytochrome P450 3A4enzyme
LomustineCytochrome P450 2D6enzyme
LomustineStathmin-4target
PaclitaxelApoptosis regulator Bcl-2target
PaclitaxelTubulin beta-1 chaintarget
PaclitaxelCytochrome P450 2C8enzyme
PaclitaxelCytochrome P450 3A4enzyme
PaclitaxelCytochrome P450 3A5enzyme
PaclitaxelCytochrome P450 3A7enzyme
PaclitaxelBile salt export pumptransporter
PaclitaxelP-glycoprotein 1transporter
PaclitaxelMultidrug resistance-associated protein 1transporter
PaclitaxelMultidrug resistance-associated protein 7transporter
PaclitaxelCytochrome P450 19A1enzyme
PaclitaxelCytochrome P450 1B1enzyme
PaclitaxelSolute carrier organic anion transporter family member 1B3transporter
PaclitaxelNuclear receptor subfamily 1 group I member 2target
PaclitaxelMicrotubule-associated protein 4target
PaclitaxelMicrotubule-associated protein 2target
PaclitaxelMicrotubule-associated protein tautarget
PaclitaxelCanalicular multispecific organic anion transporter 1transporter
DocetaxelApoptosis regulator Bcl-2target
DocetaxelTubulin beta-1 chaintarget
DocetaxelCytochrome P450 3A4enzyme
DocetaxelCytochrome P450 3A5enzyme
DocetaxelCytochrome P450 3A7enzyme
DocetaxelP-glycoprotein 1transporter
DocetaxelMultidrug resistance-associated protein 7transporter
DocetaxelCytochrome P450 1B1enzyme
DocetaxelMicrotubule-associated protein 2target
DocetaxelMicrotubule-associated protein 4target
DocetaxelMicrotubule-associated protein tautarget
DocetaxelSolute carrier organic anion transporter family member 1B3transporter
DocetaxelSolute carrier family 22 member 7transporter
DocetaxelATP-binding cassette sub-family G member 2transporter
DocetaxelCanalicular multispecific organic anion transporter 1transporter
DocetaxelMultidrug resistance-associated protein 1transporter
DocetaxelNuclear receptor subfamily 1 group I member 2target
DasatinibTyrosine-protein kinase ABL1target
DasatinibAbelson tyrosine-protein kinase 2target
DasatinibProto-oncogene tyrosine-protein kinase Srctarget
DasatinibTyrosine-protein kinase Fyntarget
DasatinibTyrosine-protein kinase Lcktarget
DasatinibTyrosine-protein kinase Yestarget
DasatinibMast/stem cell growth factor receptor Kittarget
DasatinibPlatelet-derived growth factor receptor betatarget
DasatinibEphrin type-A receptor 2target
DasatinibSignal transducer and activator of transcription 5Btarget
DasatinibCytochrome P450 3A4enzyme
DasatinibP-glycoprotein 1transporter
DasatinibATP-binding cassette sub-family G member 2transporter
DasatinibCytochrome P450 1A1enzyme
DasatinibCytochrome P450 1A2enzyme
DasatinibCytochrome P450 1B1enzyme
DasatinibCytochrome P450 3A5enzyme
DasatinibDimethylaniline monooxygenase [N-oxide-forming] 3enzyme
DasatinibTyrosine-protein kinase BTKtarget
DasatinibNuclear receptor subfamily 4 group A member 3target
DasatinibBreakpoint cluster region proteintarget
DasatinibTyrosine-protein kinase CSKtarget
DasatinibEphrin type-A receptor 5target
DasatinibEphrin type-B receptor 4target
DasatinibTyrosine-protein kinase Fgrtarget
DasatinibTyrosine-protein kinase FRKtarget
DasatinibHeat shock cognate 71 kDa proteintarget
DasatinibTyrosine-protein kinase Lyntarget
DasatinibMitogen-activated protein kinase kinase kinase MLTtarget
DasatinibMitogen-activated protein kinase 14target
DasatinibAmidophosphoribosyltransferasetarget
LapatinibEpidermal growth factor receptortarget
LapatinibReceptor tyrosine-protein kinase erbB-2target
LapatinibCytochrome P450 3A4enzyme
LapatinibCytochrome P450 2C8enzyme
LapatinibP-glycoprotein 1transporter
LapatinibAntigen peptide transporter 1transporter
LapatinibCytochrome P450 3A5enzyme
LapatinibCytochrome P450 2C19enzyme
DecitabineDNAtarget
DecitabineDNA (cytosine-5)-methyltransferase 1target
DecitabineDeoxycytidine kinaseenzyme
DecitabineUMP-CMP kinaseenzyme
DecitabineNucleoside diphosphokinaseenzyme
DecitabineCytidine deaminaseenzyme
DecitabineDNA (cytosine-5)-methyltransferase 3Atarget
DecitabineDNA (cytosine-5)-methyltransferase 3Btarget
DecitabineSodium/nucleoside cotransporter 1transporter
SunitinibPlatelet-derived growth factor receptor betatarget
SunitinibVascular endothelial growth factor receptor 1target
SunitinibVascular endothelial growth factor receptor 2target
SunitinibVascular endothelial growth factor receptor 3target
SunitinibMast/stem cell growth factor receptor Kittarget
SunitinibReceptor-type tyrosine-protein kinase FLT3target
SunitinibMacrophage colony-stimulating factor 1 receptortarget
SunitinibPlatelet-derived growth factor receptor alphatarget
SunitinibCytochrome P450 3A4enzyme
SunitinibCytochrome P450 3A5enzyme
SunitinibCytochrome P450 3A7enzyme
SunitinibMultidrug resistance-associated protein 4transporter
SunitinibP-glycoprotein 1transporter
SunitinibCanalicular multispecific organic anion transporter 1transporter
SunitinibATP-binding cassette sub-family G member 2transporter
PanitumumabEpidermal growth factor receptortarget
VorinostatHistone deacetylase 1target
VorinostatHistone deacetylase 2target
VorinostatHistone deacetylase 3target
VorinostatHistone deacetylase 6target
VorinostatHistone deacetylase 8target
VorinostatAcetoin utilization proteintarget
FotemustineThioredoxin reductase 1, cytoplasmictarget
ThiotepaCytochrome P450 2B6enzyme
ThiotepaCytochrome P450 3A4enzyme
ThiotepaDNAtarget
ThiotepaCholinesteraseenzyme
Omacetaxine mepesuccinate50S ribosomal protein L2target
Omacetaxine mepesuccinate60S ribosomal protein L3target
SatraplatinDNAtarget
BelinostatHistone deacetylasetarget
BelinostatCytochrome P450 1A2enzyme
BelinostatUDP-glucuronosyltransferase 1-4enzyme
BelinostatCytochrome P450 2C8enzyme
BelinostatCytochrome P450 2C9enzyme
BelinostatP-glycoprotein 1transporter
BelinostatCytochrome P450 3A4enzyme
TrabectedinCytochrome P450 3A4enzyme
TrabectedinCytochrome P450 2C9enzyme
TrabectedinCytochrome P450 2D6enzyme
TrabectedinCytochrome P450 2E1enzyme
TrabectedinCytochrome P450 2C19enzyme
TrabectedinDNAtarget
TrabectedinProstaglandin G/H synthase 1enzyme
RamucirumabVascular endothelial growth factor receptor 2target
Trastuzumab emtansineReceptor tyrosine-protein kinase erbB-2target
Trastuzumab emtansineP-glycoprotein 1transporter
Trastuzumab emtansineCytochrome P450 3A4enzyme
Trastuzumab emtansineCytochrome P450 3A5enzyme
RomidepsinCytochrome P450 3A4enzyme
RomidepsinCytochrome P450 3A5enzyme
RomidepsinP-glycoprotein 1transporter
RomidepsinSolute carrier organic anion transporter family member 1B3transporter
RomidepsinCytochrome P450 1A1enzyme
RomidepsinCytochrome P450 2B6enzyme
RomidepsinCytochrome P450 2C19enzyme
RomidepsinHistone deacetylase 1target
RomidepsinHistone deacetylase 2target
RomidepsinHistone deacetylase 4target
RomidepsinHistone deacetylase 6target
RomidepsinMultidrug resistance-associated protein 1target
AmrubicinDNA topoisomerase 2-alphatarget
AmrubicinDNAtarget
AmrubicinNADPH--cytochrome P450 reductaseenzyme
AmrubicinCarbonyl reductase [NADPH] 1enzyme
AmrubicinATP-binding cassette sub-family B member 5transporter
LonidamineCystic fibrosis transmembrane conductance regulatortarget
LonidamineHexokinase-1target
TemsirolimusSerine/threonine-protein kinase mTORtarget
TemsirolimusCytochrome P450 3A4enzyme
TemsirolimusCytochrome P450 3A5enzyme
TemsirolimusCytochrome P450 3A7enzyme
TemsirolimusCytochrome P450 2D6enzyme
TemsirolimusP-glycoprotein 1transporter
PertuzumabReceptor tyrosine-protein kinase erbB-2target
PanobinostatCytochrome P450 2D6enzyme
PanobinostatCytochrome P450 3A4enzyme
PanobinostatP-glycoprotein 1transporter
PanobinostatHistone deacetylasetarget
BendamustineCytochrome P450 1A2enzyme
PlicamycinDNAtarget
PonatinibTyrosine-protein kinase ABL1target
PonatinibBreakpoint cluster region proteintarget
PonatinibMast/stem cell growth factor receptor Kittarget
PonatinibProto-oncogene tyrosine-protein kinase receptor Rettarget
PonatinibAngiopoietin-1 receptortarget
PonatinibReceptor-type tyrosine-protein kinase FLT3target
PonatinibCytochrome P450 3A4enzyme
PonatinibCytochrome P450 2C8enzyme
PonatinibCytochrome P450 2D6enzyme
PonatinibCytochrome P450 3A5enzyme
PonatinibP-glycoprotein 1transporter
PonatinibATP-binding cassette sub-family G member 2transporter
PonatinibFibroblast growth factor receptor 1target
PonatinibFibroblast growth factor receptor 2target
PonatinibFibroblast growth factor receptor 3target
PonatinibFibroblast growth factor receptor 4target
PonatinibTyrosine-protein kinase Lcktarget
PonatinibProto-oncogene tyrosine-protein kinase Srctarget
PonatinibTyrosine-protein kinase Lyntarget
PonatinibVascular endothelial growth factor receptor 2target
PonatinibPlatelet-derived growth factor receptor alphatarget
TrametinibCytochrome P450 2C8enzyme
TrametinibCytochrome P450 3A4enzyme
TrametinibDual specificity mitogen-activated protein kinase kinase 1target
TrametinibDual specificity mitogen-activated protein kinase kinase 2target
DabrafenibCytochrome P450 3A4enzyme
DabrafenibCytochrome P450 2C8enzyme
DabrafenibP-glycoprotein 1transporter
DabrafenibATP-binding cassette sub-family G member 2transporter
DabrafenibSolute carrier organic anion transporter family member 1B1transporter
DabrafenibSolute carrier organic anion transporter family member 1B3transporter
DabrafenibSolute carrier family 22 member 6transporter
DabrafenibSolute carrier family 22 member 8transporter
DabrafenibSerine/threonine-protein kinase B-raftarget
DabrafenibRAF proto-oncogene serine/threonine-protein kinasetarget
DabrafenibSerine/threonine-protein kinase SIK1target
DabrafenibSerine/threonine-protein kinase Nek11target
DabrafenibLIM domain kinase 1target
DabrafenibCytochrome P450 2B6enzyme
DabrafenibCytochrome P450 2C9enzyme
ObinutuzumabB-lymphocyte antigen CD20target
MiltefosinePhospholipase D1enzyme
MiltefosineP-glycoprotein 1target
NivolumabProgrammed cell death protein 1target
PembrolizumabProgrammed cell death protein 1target
BlinatumomabB-lymphocyte antigen CD19target
BlinatumomabT-cell surface glycoprotein CD3 delta chaintarget
IdelalisibPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoformtarget
IdelalisibATP-binding cassette sub-family G member 2transporter
IdelalisibP-glycoprotein 1transporter
IdelalisibAldehyde oxidaseenzyme
IdelalisibCytochrome P450 2C8enzyme
IdelalisibCytochrome P450 2C19enzyme
IdelalisibCytochrome P450 2B6enzyme
IdelalisibCytochrome P450 3A4enzyme
IdelalisibSolute carrier organic anion transporter family member 1B1transporter
IdelalisibSolute carrier organic anion transporter family member 1B3transporter
IdelalisibCytochrome P450 3A5enzyme
IdelalisibCytochrome P450 3A43enzyme
IdelalisibCytochrome P450 3A7enzyme
IdelalisibUDP-glucuronosyltransferase 1-4enzyme
CeritinibALK tyrosine kinase receptortarget
CeritinibP-glycoprotein 1transporter
CeritinibCytochrome P450 2C9enzyme
CeritinibCytochrome P450 3A4enzyme
PalbociclibCyclin-dependent kinase 4target
PalbociclibCyclin-dependent kinase 6target
PalbociclibCytochrome P450 3A4enzyme
PalbociclibBile salt sulfotransferaseenzyme
PalbociclibP-glycoprotein 1transporter
PalbociclibATP-binding cassette sub-family G member 2transporter
PalbociclibSerum albumincarrier
PalbociclibSolute carrier family 22 member 1transporter
OlaparibPoly [ADP-ribose] polymerase 1target
OlaparibCytochrome P450 3A4enzyme
OlaparibCytochrome P450 2B6enzyme
OlaparibPoly [ADP-ribose] polymerase 2target
OlaparibPoly [ADP-ribose] polymerase 3target
OlaparibCytochrome P450 3A5enzyme
OlaparibP-glycoprotein 1transporter
OlaparibATP-binding cassette sub-family G member 2transporter
LenvatinibVascular endothelial growth factor receptor 1target
LenvatinibVascular endothelial growth factor receptor 2target
LenvatinibVascular endothelial growth factor receptor 3target
LenvatinibFibroblast growth factor receptor 1target
LenvatinibFibroblast growth factor receptor 2target
LenvatinibFibroblast growth factor receptor 3target
LenvatinibFibroblast growth factor receptor 4target
LenvatinibPlatelet-derived growth factor receptor alphatarget
LenvatinibProto-oncogene tyrosine-protein kinase receptor Rettarget
LenvatinibMast/stem cell growth factor receptor Kittarget
LenvatinibP-glycoprotein 1transporter
LenvatinibATP-binding cassette sub-family G member 2transporter
LenvatinibCytochrome P450 3A4enzyme
LenvatinibAldehyde oxidaseenzyme
LenvatinibCytochrome P450 2C8enzyme
LenvatinibCytochrome P450 2C9enzyme
LenvatinibCytochrome P450 1A2enzyme
LenvatinibCytochrome P450 2B6enzyme
LenvatinibCytochrome P450 2C19enzyme
LenvatinibSolute carrier family 22 member 6transporter
LenvatinibSolute carrier family 22 member 8transporter
LenvatinibSolute carrier family 22 member 2transporter
LenvatinibSolute carrier organic anion transporter family member 1B1transporter
LenvatinibBile salt export pumptransporter
LenvatinibCytochrome P450 2D6enzyme
NintedanibVascular endothelial growth factor receptor 1target
NintedanibVascular endothelial growth factor receptor 2target
NintedanibVascular endothelial growth factor receptor 3target
NintedanibPlatelet-derived growth factor receptor alphatarget
NintedanibPlatelet-derived growth factor receptor betatarget
NintedanibFibroblast growth factor receptor 1target
NintedanibFibroblast growth factor receptor 2target
NintedanibFibroblast growth factor receptor 3target
NintedanibReceptor-type tyrosine-protein kinase FLT3target
NintedanibTyrosine-protein kinase Lcktarget
NintedanibTyrosine-protein kinase Lyntarget
NintedanibProto-oncogene tyrosine-protein kinase Srctarget
NintedanibP-glycoprotein 1transporter
NintedanibCytochrome P450 3A4enzyme
NintedanibSolute carrier family 22 member 1transporter
NintedanibSerum albumincarrier
NintedanibUDP-glucuronosyltransferase 1-1enzyme
NintedanibUDP-glucuronosyltransferase 1-7enzyme
NintedanibUDP-glucuronosyltransferase 1-8enzyme
NintedanibUDP-glucuronosyltransferase 1-10enzyme
NintedanibATP-binding cassette sub-family G member 2transporter
TegafurCytochrome P450 2A6enzyme
TegafurThymidylate synthasetarget
TegafurCytochrome P450 1A2enzyme
TegafurCytochrome P450 2C8enzyme
TegafurCytochrome P450 2E1enzyme
TegafurCytochrome P450 3A5enzyme
TegafurThyroxine-binding globulincarrier
IxazomibCytochrome P450 3A4enzyme
IxazomibCytochrome P450 1A2enzyme
IxazomibCytochrome P450 2B6enzyme
IxazomibCytochrome P450 2C8enzyme
IxazomibCytochrome P450 2D6enzyme
IxazomibCytochrome P450 2C19enzyme
IxazomibCytochrome P450 2C9enzyme
CediranibVascular endothelial growth factor receptor 2target
Gemtuzumab ozogamicinMyeloid cell surface antigen CD33target
Gemtuzumab ozogamicinLow affinity immunoglobulin gamma Fc region receptor III-Btarget
Gemtuzumab ozogamicinLow affinity immunoglobulin gamma Fc region receptor III-Atarget
Gemtuzumab ozogamicinHigh affinity immunoglobulin gamma Fc receptor Itarget
LeuprolideGonadotropin-releasing hormone receptortarget
AldesleukinInterleukin-2 receptor subunit betatarget
AldesleukinInterleukin-2 receptor subunit alphatarget
AldesleukinCytokine receptor common subunit gammatarget
AldesleukinProstaglandin G/H synthase 2enzyme
AldesleukinCytosolic phospholipase A2enzyme
AldesleukinCytochrome P450 3A4enzyme
AldesleukinXanthine dehydrogenase/oxidaseenzyme
AldesleukinCytochrome P450 2E1enzyme
AlemtuzumabCAMPATH-1 antigentarget
AlemtuzumabLow affinity immunoglobulin gamma Fc region receptor III-Btarget
AlemtuzumabLow affinity immunoglobulin gamma Fc region receptor III-Atarget
AlemtuzumabHigh affinity immunoglobulin gamma Fc receptor Itarget
AlemtuzumabLow affinity immunoglobulin gamma Fc region receptor II-atarget
AlemtuzumabLow affinity immunoglobulin gamma Fc region receptor II-btarget
AlemtuzumabLow affinity immunoglobulin gamma Fc region receptor II-ctarget
Megestrol acetateProgesterone receptortarget
Megestrol acetateGlucocorticoid receptortarget
Megestrol acetateP-glycoprotein 1transporter
Megestrol acetateCytochrome P450 3A4enzyme
LenalidomideProstaglandin G/H synthase 2target
LenalidomideTumor necrosis factor ligand superfamily member 11target
LenalidomideCadherin-5target
LenalidomideProtein cereblontarget
LenalidomideP-glycoprotein 1transporter
FlutamideAndrogen receptortarget
FlutamideCytochrome P450 1A2enzyme
FlutamideCytochrome P450 3A4enzyme
FlutamideCytochrome P450 1A1enzyme
FlutamideCytochrome P450 1B1enzyme
FlutamideCytochrome P450 2C19enzyme
FlutamideCytochrome P450 3A5enzyme
FlutamideAryl hydrocarbon receptortarget
FlutamideNuclear receptor subfamily 1 group I member 2target
NilutamideAndrogen receptortarget
NilutamideCytochrome P450 2C19enzyme
NilutamideNADPH--cytochrome P450 reductaseenzyme
TamoxifenEstrogen receptor alphatarget
TamoxifenEstrogen receptor betatarget
TamoxifenCytochrome P450 2C9enzyme
TamoxifenCytochrome P450 3A4enzyme
TamoxifenCytochrome P450 2D6enzyme
TamoxifenCytochrome P450 2C8enzyme
TamoxifenCytochrome P450 2B6enzyme
TamoxifenLiver carboxylesterase 1enzyme
TamoxifenCytochrome P450 3A5enzyme
TamoxifenCytochrome P450 1A1enzyme
TamoxifenCytochrome P450 1B1enzyme
TamoxifenCytochrome P450 2C19enzyme
TamoxifenDimethylaniline monooxygenase [N-oxide-forming] 1enzyme
TamoxifenDimethylaniline monooxygenase [N-oxide-forming] 3enzyme
TamoxifenCytochrome P450 3A7enzyme
TamoxifenP-glycoprotein 1transporter
TamoxifenATP-binding cassette sub-family G member 2transporter
TamoxifenCytochrome P450 19A1enzyme
TamoxifenCytochrome P450 2A6enzyme
TamoxifenCytochrome P450 2E1enzyme
TamoxifenUDP-glucuronosyltransferase 1-10enzyme
TamoxifenSulfotransferase 1A1enzyme
TamoxifenCanalicular multispecific organic anion transporter 1transporter
Tamoxifen3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerasetarget
TamoxifenProtein kinase Ctarget
TamoxifenAndrogen receptortarget
TamoxifenPotassium voltage-gated channel subfamily H member 2target
TamoxifenNuclear receptor subfamily 1 group I member 2target
TamoxifenEstrogen-related receptor gammatarget
TamoxifenSex hormone-binding globulintarget
TamoxifenBile salt export pumptransporter
TamoxifenThyroxine-binding globulincarrier
TamoxifenBile salt sulfotransferaseenzyme
TamoxifenCytochrome P450 1A2enzyme
TamoxifenUDP-glucuronosyltransferase 2B7enzyme
TamoxifenUDP-glucuronosyltransferase 2B17enzyme
TamoxifenEstrogen sulfotransferaseenzyme
TamoxifenATP-binding cassette sub-family A member 1transporter
TamoxifenMitogen-activated protein kinase 8target
TamoxifenSerum albumincarrier
FulvestrantEstrogen receptor alphatarget
FulvestrantCytochrome P450 3A4enzyme
FulvestrantUDP-glucuronosyltransferase 1-1enzyme
ExemestaneCytochrome P450 19A1target
ExemestaneCytochrome P450 3A4enzyme
ExemestaneCytochrome P450 19A1enzyme
LetrozoleCytochrome P450 19A1target
LetrozoleCytochrome P450 3A4enzyme
LetrozoleCytochrome P450 2A6enzyme
LetrozoleCytochrome P450 19A1enzyme
LetrozoleCytochrome P450 2C19enzyme
LetrozoleUDP-glucuronosyltransferase 2B7enzyme
LetrozoleSerum albumincarrier
LetrozoleP-glycoprotein 1transporter
BicalutamideAndrogen receptortarget
BicalutamideCytochrome P450 3A4enzyme
BicalutamideCytochrome P450 2C19enzyme
BicalutamideCytochrome P450 2C9enzyme
BicalutamideCytochrome P450 2D6enzyme
BicalutamideP-glycoprotein 1transporter
AnastrozoleCytochrome P450 19A1target
AnastrozoleP-glycoprotein 1transporter
AnastrozoleCytochrome P450 3A4enzyme
AnastrozoleCytochrome P450 3A5enzyme
AnastrozoleCytochrome P450 2C8enzyme
AnastrozoleUDP-glucuronosyltransferase 1-4enzyme
AnastrozoleUDP-glucuronosyltransferase 1-3enzyme
AnastrozoleUDP-glucuronosyltransferase 2B7enzyme
AnastrozoleCytochrome P450 1A2enzyme
AnastrozoleCytochrome P450 2C9enzyme
EverolimusSerine/threonine-protein kinase mTORtarget
EverolimusCytochrome P450 3A4enzyme
EverolimusSolute carrier organic anion transporter family member 1B1transporter
EverolimusSolute carrier organic anion transporter family member 1B3transporter
EverolimusSolute carrier organic anion transporter family member 1A2transporter
EverolimusCytochrome P450 2D6enzyme
EverolimusP-glycoprotein 1transporter
NelarabineDNAtarget
NelarabineAdenosine deaminaseenzyme
NelarabineDeoxycytidine kinaseenzyme
NelarabineDeoxyguanosine kinase, mitochondrialenzyme
NelarabineDNA polymerase alpha catalytic subunittarget
NilotinibTyrosine-protein kinase ABL1target
NilotinibMast/stem cell growth factor receptor Kittarget
NilotinibCytochrome P450 2D6enzyme
NilotinibCytochrome P450 2C8enzyme
NilotinibCytochrome P450 2C9enzyme
NilotinibCytochrome P450 3A4enzyme
NilotinibP-glycoprotein 1transporter
NilotinibATP-binding cassette sub-family G member 2transporter
NilotinibUDP-glucuronosyltransferase 1-1transporter
NilotinibCytochrome P450 2B6enzyme
NilotinibSolute carrier organic anion transporter family member 1B1transporter
VandetanibVascular endothelial growth factor Atarget
VandetanibEpidermal growth factor receptortarget
VandetanibMultidrug resistance-associated protein 1transporter
VandetanibATP-binding cassette sub-family G member 2transporter
VandetanibProto-oncogene tyrosine-protein kinase receptor Rettarget
VandetanibDimethylaniline monooxygenase [N-oxide-forming] 1enzyme
VandetanibDimethylaniline monooxygenase [N-oxide-forming] 3enzyme
VandetanibProtein-tyrosine kinase 6target
VandetanibAngiopoietin-1 receptortarget
VandetanibAlpha-1-acid glycoprotein 1carrier
VandetanibSerum albumincarrier
VandetanibCytochrome P450 3A4enzyme
VandetanibSolute carrier family 22 member 2transporter
VandetanibP-glycoprotein 1transporter
IpilimumabCytotoxic T-lymphocyte protein 4target
PazopanibVascular endothelial growth factor receptor 1target
PazopanibVascular endothelial growth factor receptor 2target
PazopanibVascular endothelial growth factor receptor 3target
PazopanibPlatelet-derived growth factor receptor alphatarget
PazopanibPlatelet-derived growth factor receptor betatarget
PazopanibMast/stem cell growth factor receptor Kittarget
PazopanibCytochrome P450 3A4enzyme
PazopanibCytochrome P450 2D6enzyme
PazopanibCytochrome P450 2C8enzyme
PazopanibCytochrome P450 1A2enzyme
PazopanibP-glycoprotein 1transporter
PazopanibATP-binding cassette sub-family G member 2transporter
PazopanibSolute carrier organic anion transporter family member 1B1transporter
PazopanibUDP-glucuronosyltransferase 1-1transporter
PazopanibFibroblast growth factor receptor 3target
PazopanibTyrosine-protein kinase ITK/TSKtarget
PazopanibFibroblast growth factor 1target
PazopanibSH2B adapter protein 3target
CatumaxomabEpithelial cell adhesion moleculetarget
CatumaxomabLow affinity immunoglobulin gamma Fc region receptor II-atarget
CatumaxomabLow affinity immunoglobulin gamma Fc region receptor III-Atarget
CatumaxomabLow affinity immunoglobulin gamma Fc region receptor III-Btarget
CatumaxomabT-cell surface glycoprotein CD3 epsilon chaintarget
CatumaxomabHigh affinity immunoglobulin gamma Fc receptor Itarget
BosutinibBreakpoint cluster region proteintarget
BosutinibTyrosine-protein kinase ABL1target
BosutinibTyrosine-protein kinase Lyntarget
BosutinibTyrosine-protein kinase HCKtarget
BosutinibProto-oncogene tyrosine-protein kinase Srctarget
BosutinibP-glycoprotein 1transporter
BosutinibCytochrome P450 3A4enzyme
BosutinibCyclin-dependent kinase 2target
BosutinibDual specificity mitogen-activated protein kinase kinase 1target
BosutinibDual specificity mitogen-activated protein kinase kinase 2target
BosutinibMitogen-activated protein kinase kinase kinase 2target
BosutinibCalcium/calmodulin-dependent protein kinase type II subunit gammatarget
BosutinibCytochrome P450 2C8enzyme
AxitinibVascular endothelial growth factor receptor 1target
AxitinibVascular endothelial growth factor receptor 2target
AxitinibVascular endothelial growth factor receptor 3target
AxitinibCytochrome P450 3A4enzyme
AxitinibCytochrome P450 3A5enzyme
AxitinibCytochrome P450 1A2enzyme
AxitinibCytochrome P450 2C19enzyme
AxitinibUDP-glucuronosyltransferase 1-1enzyme
AxitinibP-glycoprotein 1transporter
AxitinibSolute carrier organic anion transporter family member 1B1transporter
OfatumumabB-lymphocyte antigen CD20target
CabazitaxelCytochrome P450 3A4enzyme
CabazitaxelCytochrome P450 3A5enzyme
CabazitaxelCytochrome P450 2C8enzyme
CabazitaxelP-glycoprotein 1transporter
CabazitaxelATP-binding cassette sub-family G member 2transporter
CabazitaxelTubulin alpha-4A chaintarget
CabazitaxelTubulin beta-1 chaintarget
CabazitaxelSolute carrier organic anion transporter family member 1B1transporter
CabazitaxelSolute carrier organic anion transporter family member 1B3transporter
VismodegibSmoothened homologtarget
VismodegibCytochrome P450 2C9enzyme
VismodegibCytochrome P450 3A4enzyme
VismodegibP-glycoprotein 1transporter
VismodegibCytochrome P450 2C8enzyme
VismodegibCytochrome P450 2C19enzyme
VismodegibATP-binding cassette sub-family G member 2transporter
VismodegibSerum albumincarrier
VismodegibAlpha-1-acid glycoprotein 1carrier
CrizotinibCytochrome P450 3A4enzyme
CrizotinibCytochrome P450 3A5enzyme
CrizotinibP-glycoprotein 1transporter
CrizotinibALK tyrosine kinase receptortarget
CrizotinibHepatocyte growth factor receptortarget
CrizotinibCytochrome P450 2B6enzyme
CrizotinibCytochrome P450 3A Subfamilyenzyme
Brentuximab vedotinTumor necrosis factor receptor superfamily member 8target
Brentuximab vedotinCytochrome P450 3A4enzyme
Brentuximab vedotinATP-binding cassette sub-family B member 5transporter
EribulinApoptosis regulator Bcl-2target
EribulinTubulin beta-1 chaintarget
RuxolitinibTyrosine-protein kinase JAK1target
RuxolitinibTyrosine-protein kinase JAK2target
RuxolitinibCytochrome P450 3A4enzyme
VemurafenibSerum albumincarrier
VemurafenibAlpha-1-acid glycoprotein 1carrier
VemurafenibCytochrome P450 1A2enzyme
VemurafenibCytochrome P450 2D6enzyme
VemurafenibCytochrome P450 3A4enzyme
VemurafenibSerine/threonine-protein kinase B-raftarget
VemurafenibMultidrug resistance-associated protein 1transporter
VemurafenibATP-binding cassette sub-family G member 2transporter
VemurafenibCytochrome P450 2C9enzyme
VemurafenibCytochrome P450 2C8enzyme
VemurafenibCytochrome P450 2B6enzyme
VemurafenibP-glycoprotein 1transporter
CarfilzomibP-glycoprotein 1transporter
CarfilzomibProteasome subunit beta type-5target
CarfilzomibProteasome subunit beta type-9target
CarfilzomibProteasome subunit beta type-10target
CarfilzomibProteasome subunit beta type-8target
CarfilzomibProteasome subunit beta type-1target
CarfilzomibProteasome subunit beta type-2target
RegorafenibCytochrome P450 3A4enzyme
RegorafenibUDP-glucuronosyltransferase 1-9enzyme
RegorafenibProto-oncogene tyrosine-protein kinase receptor Rettarget
RegorafenibVascular endothelial growth factor receptor 1target
RegorafenibVascular endothelial growth factor receptor 2target
RegorafenibVascular endothelial growth factor receptor 3target
RegorafenibMast/stem cell growth factor receptor Kittarget
RegorafenibPlatelet-derived growth factor receptor alphatarget
RegorafenibPlatelet-derived growth factor receptor betatarget
RegorafenibFibroblast growth factor receptor 1target
RegorafenibFibroblast growth factor receptor 2target
RegorafenibAngiopoietin-1 receptortarget
RegorafenibDiscoidin domain-containing receptor 2target
RegorafenibHigh affinity nerve growth factor receptortarget
RegorafenibEphrin type-A receptor 2target
RegorafenibRAF proto-oncogene serine/threonine-protein kinasetarget
RegorafenibSerine/threonine-protein kinase B-raftarget
RegorafenibCytochrome P450 2C8enzyme
RegorafenibCytochrome P450 2C9enzyme
RegorafenibCytochrome P450 2B6enzyme
RegorafenibMitogen-activated protein kinase 11target
RegorafenibTyrosine-protein kinase FRKtarget
RegorafenibTyrosine-protein kinase ABL1target
RegorafenibP-glycoprotein 1transporter
RegorafenibATP-binding cassette sub-family G member 2transporter
RegorafenibUDP-glucuronosyltransferase 1-1enzyme
AfatinibEpidermal growth factor receptortarget
AfatinibReceptor tyrosine-protein kinase erbB-2target
AfatinibReceptor tyrosine-protein kinase erbB-4target
AfatinibP-glycoprotein 1transporter
AfatinibATP-binding cassette sub-family G member 2transporter
IbrutinibTyrosine-protein kinase BTKtarget
IbrutinibCytochrome P450 3A4enzyme
IbrutinibCytochrome P450 3A5enzyme
IbrutinibSerum albumincarrier
Ibrutinibalpha1-acid glycoproteincarrier
IbrutinibCytochrome P450 2D6enzyme
NecitumumabEpidermal growth factor receptortarget
AbirateroneSteroid 17-alpha-hydroxylase/17,20 lyasetarget
AbirateroneSerum albumincarrier
AbirateroneAlpha-1-acid glycoprotein 1carrier
AbirateroneCytochrome P450 3A4enzyme
AbirateroneBile salt sulfotransferaseenzyme
AbirateroneMultidrug resistance-associated protein 1transporter
AbirateroneCytochrome P450 2D6enzyme
AbirateroneCytochrome P450 2C8enzyme
AbirateroneCytochrome P450 1A2enzyme
AbirateroneCytochrome P450 2C19enzyme
AbirateroneCytochrome P450 2C9enzyme
MidostaurinProtein kinase C alpha typetarget
MidostaurinVascular endothelial growth factor receptor 2target
MidostaurinMast/stem cell growth factor receptor Kittarget
MidostaurinPlatelet-derived growth factor receptor alphatarget
MidostaurinPlatelet-derived growth factor receptor betatarget
MidostaurinReceptor-type tyrosine-protein kinase FLT3target
MidostaurinCytochrome P450 3A Subfamilyenzyme
MidostaurinCytochrome P450 1A2enzyme
MidostaurinCytochrome P450 2B6enzyme
MidostaurinCytochrome P450 2C8enzyme
MidostaurinCytochrome P450 2C9enzyme
MidostaurinCytochrome P450 2C19enzyme
MidostaurinCytochrome P450 2D6enzyme
MidostaurinCytochrome P450 2E1enzyme
MidostaurinCytochrome P450 3A4enzyme
MidostaurinCytochrome P450 3A5enzyme
MidostaurinCytochrome P450 3A7enzyme
MidostaurinCytochrome P450 3A43enzyme
TriptorelinGonadotropin-releasing hormone receptortarget
PomalidomideCytochrome P450 1A2enzyme
PomalidomideCytochrome P450 3A4enzyme
PomalidomideP-glycoprotein 1transporter
PomalidomideProtein cereblontarget
PomalidomideTumor necrosis factortarget
PomalidomideProstaglandin G/H synthase 2target
OsimertinibEpidermal growth factor receptortarget
OsimertinibP-glycoprotein 1transporter
OsimertinibATP-binding cassette sub-family G member 2transporter
OsimertinibCytochrome P450 3A4enzyme
OsimertinibCytochrome P450 1A2enzyme
DaratumumabADP-ribosyl cyclase 1target
TretinoinRetinoic acid receptor gammatarget
TretinoinRetinoic acid receptor RXR-betatarget
TretinoinRetinal dehydrogenase 1target
TretinoinRetinoic acid-induced protein 3target
TretinoinRetinoic acid receptor RXR-gammatarget
TretinoinRetinal dehydrogenase 2target
TretinoinRetinoic acid receptor responder protein 1target
TretinoinCytochrome P450 2C8enzyme
TretinoinCellular retinoic acid-binding protein 1transporter
TretinoinCellular retinoic acid-binding protein 2transporter
TretinoinCytochrome P450 2B6enzyme
TretinoinCytochrome P450 3A4enzyme
TretinoinCytochrome P450 3A5enzyme
TretinoinCytochrome P450 2A6enzyme
TretinoinCytochrome P450 3A7enzyme
TretinoinCytochrome P450 2C18enzyme
TretinoinCytochrome P450 2C9enzyme
TretinoinCytochrome P450 4A11enzyme
TretinoinCytochrome P450 1A1enzyme
TretinoinRetinoic acid receptor alphatarget
TretinoinRetinoic acid receptor betatarget
TretinoinLipocalin-1target
TretinoinOdorant-binding protein 2atarget
TretinoinRetinol-binding protein 4target
TretinoinSerum albumincarrier
Tretinoin[Pyruvate dehydrogenase [lipoamide]] kinase isozyme 4, mitochondrialtarget
TretinoinRetinoic acid receptor RXR-alphatarget
TretinoinCytochrome P450 26A1target
TretinoinCytochrome P450 26B1target
TretinoinCytochrome P450 26C1target
TretinoinHematopoietic prostaglandin D synthasetarget
GoserelinLutropin-choriogonadotropic hormone receptortarget
GoserelinGonadotropin-releasing hormone receptortarget
TositumomabB-lymphocyte antigen CD20target
TositumomabLow affinity immunoglobulin gamma Fc region receptor II-btarget
OctreotideMyeloperoxidaseenzyme
OctreotideCytochrome P450 3A4enzyme
OctreotideSomatostatin receptortarget
OctreotideSerum albumincarrier
OctreotideP-glycoprotein 1transporter
OctreotideCanalicular multispecific organic anion transporter 1transporter
CabergolineDopamine D2 receptortarget
Cabergoline5-hydroxytryptamine receptor 2Btarget
CabergolineDopamine D3 receptortarget
Cabergoline5-hydroxytryptamine receptor 2Atarget
CabergolineAlpha-2B adrenergic receptortarget
Cabergoline5-hydroxytryptamine receptor 1Dtarget
CabergolineDopamine D4 receptortarget
CabergolineAlpha-2A adrenergic receptortarget
Cabergoline5-hydroxytryptamine receptor 1Atarget
CabergolineAlpha-2C adrenergic receptortarget
CabergolineDopamine D5 receptortarget
CabergolineDopamine D1 receptortarget
Cabergoline5-hydroxytryptamine receptor 1Btarget
Cabergoline5-hydroxytryptamine receptor 2Ctarget
CabergolineCytochrome P450 3A4enzyme
Cabergoline5-hydroxytryptamine receptor 7target
CabergolineAlpha-1A adrenergic receptortarget
CabergolineAlpha-1B adrenergic receptortarget
CabergolineAlpha-1D adrenergic receptortarget
CabergolineBeta-1 adrenergic receptortarget
CabergolineBeta-2 adrenergic receptortarget
CabergolineD(1) dopamine receptortarget
CabergolineP-glycoprotein 1transporter
ChlorotrianiseneEstrogen receptor alphatarget
ChlorotrianiseneCytochrome P450 19A1enzyme
Pamidronic acidFarnesyl pyrophosphate synthasetarget
Pamidronic acidHydroxylapatitetarget
Pamidronic acidGeranylgeranyl pyrophosphate synthasetarget
Pamidronic acidCaspase-3target
Pamidronic acidCaspase-9target
FloxuridineThymidylate synthasetarget
FloxuridineThymidine phosphorylaseenzyme
FloxuridineCytochrome P450 2C9enzyme
FloxuridineThyroxine-binding globulincarrier
AminoglutethimideCytochrome P450 19A1target
AminoglutethimideCytochrome P450 2C19enzyme
AminoglutethimideCytochrome P450 3A4enzyme
AminoglutethimideCholesterol side-chain cleavage enzyme, mitochondrialtarget
ToremifeneEstrogen receptor alphatarget
ToremifeneCytochrome P450 3A4enzyme
ToremifeneP-glycoprotein 1transporter
ToremifeneCytochrome P450 1A1enzyme
ToremifeneSex hormone-binding globulintarget
Medroxyprogesterone acetateProgesterone receptortarget
Medroxyprogesterone acetateEstrogen receptor alphatarget
Medroxyprogesterone acetateCytochrome P450 3A4enzyme
Medroxyprogesterone acetateCytochrome P450 2C8enzyme
Medroxyprogesterone acetate3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type 2enzyme
Medroxyprogesterone acetateCytochrome P450 2C9enzyme
Medroxyprogesterone acetateCytochrome P450 3A1enzyme
Medroxyprogesterone acetateSerum albumincarrier
Medroxyprogesterone acetateP-glycoprotein 1target
Medroxyprogesterone acetateGABA(A) Receptortarget
Medroxyprogesterone acetateP-glycoprotein 1transporter
PrednisoneGlucocorticoid receptortarget
PrednisoneCytochrome P450 3A4enzyme
PrednisoneP-glycoprotein 1transporter
PrednisoneSolute carrier organic anion transporter family member 1A2transporter
PrednisoneCytochrome P450 2C19enzyme
PrednisoneSerum albumincarrier
PrednisoneCytochrome P450 3A5enzyme
PrednisoneCorticosteroid-binding globulincarrier
PrednisoneCytochrome P450 3A Subfamilyenzyme
PrednisoneCytochrome P450 2A6enzyme
PrednisoneCytochrome P450 1B1enzyme
PrednisoneCytochrome P450 2B6enzyme
PrednisoneCytochrome P450 2C8enzyme
PrednisoneCytochrome P450 2C9enzyme
PrednisoneCorticosteroid 11-beta-dehydrogenase isozyme 1enzyme
ImiquimodToll-like receptor 7target
ImiquimodToll-like receptor 8target
ImiquimodCytochrome P450 3A4enzyme
Uracil mustardDNAtarget
PrednisoloneCorticosteroid-binding globulincarrier
PrednisoloneCytochrome P450 3A4enzyme
PrednisoloneGlucocorticoid receptortarget
PrednisoloneSolute carrier organic anion transporter family member 1A2transporter
PrednisoloneP-glycoprotein 1transporter
PrednisoloneSerum albumincarrier
TestolactoneCytochrome P450 19A1target
MethylprednisoloneGlucocorticoid receptortarget
MethylprednisoloneCytochrome P450 3A4enzyme
MethylprednisoloneP-glycoprotein 1transporter
MethylprednisoloneCytochrome P450 3A Subfamilyenzyme
MethylprednisoloneCytochrome P450 2A6enzyme
MethylprednisoloneCytochrome P450 1B1enzyme
MethylprednisoloneCytochrome P450 2B6enzyme
MethylprednisoloneCytochrome P450 2C8enzyme
MethylprednisoloneCytochrome P450 2C9enzyme
MethylprednisoloneCytochrome P450 2C19enzyme
MethylprednisoloneAnnexin A1target
Methylprednisolone20-ketosteroid reductase (20-hydroxysteroid dehydrogenase)enzyme
Methylprednisolone11beta-hydroxysteroid dehydrogenaseenzyme
MethylprednisoloneSerum albumincarrier
ThalidomideTumor necrosis factortarget
ThalidomideNuclear factor NF-kappa-B p105 subunittarget
ThalidomideProstaglandin G/H synthase 2target
ThalidomideCytochrome P450 2C19enzyme
ThalidomideCytochrome P450 1A1enzyme
ThalidomideCytochrome P450 2E1enzyme
ThalidomideCytochrome P450 2C9enzyme
ThalidomideProstaglandin G/H synthase 1enzyme
ThalidomideProstaglandin G/H synthase 2enzyme
ThalidomideCytochrome P450 3A5enzyme
ThalidomideFibroblast growth factor receptor 2target
ThalidomideDNAtarget
ThalidomideProtein cereblontarget
Thalidomidealpha1-acid glycoproteintarget
Trilostane3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type 1target
Trilostane3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type 2target
TrilostaneEstrogen receptor betatarget
TrilostaneEstrogen receptor alphatarget
DexamethasoneGlucocorticoid receptortarget
DexamethasoneAnnexin A1target
DexamethasoneNitric oxide synthase, inducibletarget
DexamethasoneNuclear receptor subfamily 0 group B member 1target
DexamethasoneCytochrome P450 3A4enzyme
DexamethasoneCytochrome P450 3A5enzyme
DexamethasoneCytochrome P450 3A7enzyme
DexamethasoneBile salt export pumptransporter
DexamethasoneP-glycoprotein 1transporter
DexamethasoneCanalicular multispecific organic anion transporter 1transporter
DexamethasoneSolute carrier organic anion transporter family member 1A2transporter
DexamethasoneATP-binding cassette sub-family G member 2transporter
DexamethasoneSteroid 17-alpha-hydroxylase/17,20 lyaseenzyme
DexamethasoneCytochrome P450 1A1enzyme
DexamethasoneCytochrome P450 2A6enzyme
DexamethasoneCytochrome P450 2B6enzyme
DexamethasoneCytochrome P450 2C19enzyme
DexamethasoneCytochrome P450 2C8enzyme
DexamethasoneCytochrome P450 2E1enzyme
DexamethasoneCytochrome P450 3A43enzyme
DexamethasoneCytochrome P450 4A11enzyme
DexamethasoneNuclear receptor subfamily 1 group I member 2target
DexamethasoneCytochrome P450 11B1, mitochondrialenzyme
DexamethasoneSerum albumincarrier
DexamethasoneCorticosteroid 11-beta-dehydrogenase isozyme 2enzyme
DexamethasoneCorticosteroid 11-beta-dehydrogenase isozyme 1enzyme
DexamethasoneSolute carrier family 22 member 8transporter
8-azaguaninePurine nucleoside phosphorylasetarget
8-azaguanineCytochrome P450 1A2enzyme
7-Hydroxystaurosporine3-phosphoinositide-dependent protein kinase 1target
HadacidinAdenylosuccinate synthetasetarget
HadacidinAdenylosuccinate synthetase isozyme 1target
HadacidinAdenylosuccinate synthetasetarget
2-MethoxyestradiolHypoxia-inducible factor 1-alphatarget
2-MethoxyestradiolSex hormone-binding globulincarrier
2-MethoxyestradiolCatechol O-methyltransferasetarget
2-MethoxyestradiolCytochrome P450 1A1target
2-MethoxyestradiolCytochrome P450 1B1target
2-MethoxyestradiolCytochrome P450 19A1target
GeldanamycinHeat shock protein HSP 90-alphatarget
GeldanamycinHeat shock protein HSP 90-betatarget
GeldanamycinEndoplasmintarget
FumagillinMethionine aminopeptidase 2target
PatupiloneTubulin alpha-3C/D chaintarget
PatupiloneTubulin beta chaintarget
PatupiloneTubulin beta-1 chaintarget
PatupiloneTubulin beta-4B chaintarget
PatupiloneTubulin beta-4A chaintarget
PatupiloneTubulin alpha-4A chaintarget
PatupiloneTubulin beta-3 chaintarget
PatupiloneTubulin alpha-1C chaintarget
PatupiloneTubulin alpha-8 chaintarget
PatupiloneTubulin alpha-1B chaintarget
PatupiloneTubulin alpha-1A chaintarget
PatupiloneCytochrome P450 3A4enzyme
Sparfosic acidAspartate carbamoyltransferase catalytic chaintarget
Sparfosic acidCAD proteintarget
AlvocidibGlycogen phosphorylase, muscle formtarget
AlvocidibCyclin-dependent kinase 7target
AlvocidibCyclin-dependent kinase 5target
AlvocidibCyclin-dependent kinase 9target
AlvocidibCyclin-dependent kinase 1target
AlvocidibCyclin-dependent kinase 6target
AlvocidibEpidermal growth factor receptortarget
AlvocidibCyclin-dependent kinase 4target
AlvocidibCyclin-dependent kinase 8target
AlvocidibCyclin-dependent kinase 2target
AlvocidibATP-binding cassette sub-family G member 2transporter
AlvocidibGlycogen phosphorylase, brain formtarget
AlvocidibGlycogen phosphorylase, liver formtarget
AlvocidibUDP-glucuronosyltransferase 1-1enzyme
2-(4-Chlorophenyl)-5-QuinoxalinecarboxamidePoly [ADP-ribose] polymerase 1target
Rhodamine 6GHTH-type transcriptional regulator QacRtarget
Rhodamine 6GAcriflavine resistance protein Btarget
Rhodamine 6GMultidrug resistance-associated protein 1transporter
Rhodamine 6GP-glycoprotein 1transporter
BatimastatNeutrophil collagenasetarget
BatimastatMacrophage metalloelastasetarget
BatimastatMatrix metalloproteinase-16target
BatimastatDisintegrin and metalloproteinase domain-containing protein 28target
BatimastatA disintegrin and metalloproteinase with thrombospondin motifs 5target
TretazicarOxygen-insensitive NAD(P)H nitroreductasetarget
TretazicarRibosyldihydronicotinamide dehydrogenase [quinone]target
SeocalcitolVitamin D3 receptortarget
NebularineAdenosine deaminasetarget
AfimoxifeneEstrogen receptor alphatarget
AfimoxifeneEstrogen receptor betatarget
AfimoxifeneEstrogen-related receptor gammatarget
AfimoxifeneTrefoil factor 1target
AfimoxifeneSteroid hormone receptor ERR1target
AfimoxifeneNuclear receptor subfamily 1 group I member 2target
AfimoxifeneSex hormone-binding globulintarget
FleroxacinDNA topoisomerase 2-alphatarget
FleroxacinDNA gyrase subunit Atarget
FleroxacinDNA topoisomerase 4 subunit Atarget
MetoprineHistamine N-methyltransferasetarget
CamptothecinDNA topoisomerase 1target
CamptothecinP-glycoprotein 1transporter
CamptothecinATP-binding cassette sub-family G member 2transporter
CamptothecinSerum albumincarrier
SuraminNAD-dependent protein deacylase sirtuin-5, mitochondrialtarget
SuraminComplement control protein C3target
SuraminPhospholipase A2, membrane associatedtarget
SuraminProthrombintarget
SuraminP2Y purinoceptor 2target
SuraminFollicle-stimulating hormone receptortarget
SuraminRyanodine receptor 1target
SuraminArylsulfatase Aenzyme
SuraminCytosolic phospholipase A2enzyme
UrethaneCytosolic phospholipase A2enzyme
UrethaneMyeloperoxidaseenzyme
UrethaneAldehyde oxidaseenzyme
Cyproterone acetateAndrogen receptortarget
Cyproterone acetateProstate-specific antigentarget
Cyproterone acetateCytochrome P450 3A4enzyme
Cyproterone acetateCytochrome P450 19A1enzyme
TirapazamineDNAtarget
TirapazamineCytochrome P450 2E1enzyme
HalofuginoneCollagen alpha-1(I) chaintarget
Halofuginone72 kDa type IV collagenasetarget
VapreotideNeurokinin 1 receptortarget
VapreotideSomatostatin receptor type 2target
VapreotideSomatostatin receptor type 5target
VapreotideCytochrome P450 3A4enzyme
RanpirnaseDNAtarget
PirfenidoneFurintarget
PirfenidoneCytochrome P450 1A2enzyme
TipifarnibProtein farnesyltransferase subunit betatarget
TipifarnibP-glycoprotein 1transporter
TroxacitabineDNAtarget
TroxacitabineDeoxycytidine kinaseenzyme
AmonafideDNA topoisomerase 2-alphatarget
AmonafideDNA topoisomerase 2-betatarget
FenretinideRetinol-binding protein 4carrier
TetrathiomolybdateAmyloid beta A4 proteintarget
ElsamitrucinDNAtarget
ElsamitrucinDNA topoisomerase 1target
ElsamitrucinDNA topoisomerase 2-alphatarget
Gallium nitrateSerotransferrincarrier
Gallium nitrateRibonucleoside-diphosphate reductase subunit M2target
Gallium nitrateProtein-tyrosine-phosphatasetarget
Gallium nitrateInterleukin-1 betatarget
Gallium nitrateHydroxylapatitetarget
Gallium nitrateOsteocalcintarget
Gallium nitrateV-type proton ATPase subunit B, brain isoformtarget
Gallium nitrateTransferrin receptortransporter
EcabetNADPH oxidase organizer 1target
EcabetUrease subunit alphatarget
CanertinibEpidermal growth factor receptortarget
Motexafin gadoliniumThioredoxin reductase 1, cytoplasmictarget
Motexafin gadoliniumThioredoxin reductase 2, mitochondrialtarget
Motexafin gadoliniumRibonucleoside-diphosphate reductase subunit M2target
AlanosineAspartate carbamoyltransferase catalytic chaintarget
AlanosineAdenylosuccinate synthetase isozyme 2target
AlanosineAdenylosuccinate synthetase isozyme 1target
AlanosineCystine/glutamate transportertransporter
PalifosfamideDNA (cytosine-5)-methyltransferase 1target
IrofulvenFar upstream element-binding protein 1target
KOS-1584Cytochrome P450 3A4enzyme
RubitecanDNA topoisomerase 1target
GarenoxacinCytochrome P450 1A2enzyme
SeliciclibCyclin-dependent kinase 1target
SeliciclibCyclin-dependent kinase 2target
SeliciclibMitogen-activated protein kinase 3target
SeliciclibMitogen-activated protein kinase 1target
SeliciclibCyclin-dependent kinase 7target
SeliciclibCyclin-dependent kinase 9target
SeliciclibCasein kinase I isoform epsilontarget
SeliciclibProstaglandin G/H synthase 2enzyme
EflornithineOrnithine decarboxylasetarget
ExisulindcAMP-specific 3',5'-cyclic phosphodiesterase 4Dtarget
ExisulindcAMP-specific 3',5'-cyclic phosphodiesterase 4Ctarget
ExisulindcGMP-specific 3',5'-cyclic phosphodiesterasetarget
ExisulindcGMP-dependent 3',5'-cyclic phosphodiesterasetarget
ExisulindGlutathione S-transferase Ptarget
ExisulindAldose reductasetarget
ExisulindAldo-keto reductase family 1 member B10target
AnnamycinDNA topoisomerase 2-alphatarget
AnnamycinDNAtarget
AnnamycinP-glycoprotein 1transporter
Endostatin72 kDa type IV collagenasetarget
EndostatinMatrix metalloproteinase-9target
EndostatinCollagenase 3target
EndostatinFocal adhesion kinase 1target
EndostatinE-selectintarget
EndostatinCytochrome P450 19A1enzyme
TezacitabineRibonucleoside-diphosphate reductase large subunittarget
TezacitabineThymidine phosphorylaseenzyme
SemaxanibVascular endothelial growth factor receptor 2target
SemaxanibProstaglandin G/H synthase 2enzyme
PorfiromycinXanthine dehydrogenase/oxidaseenzyme
MethyltestosteroneCytochrome P450 2B6enzyme
MethyltestosteroneCytochrome P450 3A4enzyme
MethyltestosteroneAndrogen receptortarget
MethyltestosteroneSolute carrier organic anion transporter family member 1A2transporter
MethyltestosteroneSolute carrier family 22 member 8transporter
MethyltestosteroneSerum albumincarrier
MethyltestosteroneSex hormone-binding globulincarrier
MethyltestosteroneEstrogen receptor alphatarget
MethyltestosteroneCytochrome P450 19A1enzyme
BesifloxacinDNA topoisomerase 4 subunit Atarget
BesifloxacinDNA topoisomerase 4 subunit Atarget
BesifloxacinDNA gyrase subunit Atarget
BesifloxacinDNA gyrase subunit Atarget
BesifloxacinCytochrome P450 1A2enzyme
Hydroxyprogesterone caproateProgesterone receptortarget
Hydroxyprogesterone caproateCytochrome P450 3A4enzyme
Hydroxyprogesterone caproateCytochrome P450 3A5enzyme
Hydroxyprogesterone caproateCytochrome P450 2C19enzyme
LanreotideSomatostatin receptor type 2target
LanreotideSomatostatin receptor type 5target
LanreotideCytochrome P450 3A4enzyme
Phenylbutyric acidAromatic-amino-acid aminotransferasetarget
Phenylbutyric acidThermolysintarget
Phenylbutyric acidCytochrome P450 2D6enzyme
VeliparibPoly [ADP-ribose] polymerase 1target
VeliparibPoly [ADP-ribose] polymerase 2target
HexestrolAldo-keto reductase family 1 member C1target
HexestrolEstrogen receptor alphatarget
HexestrolNuclear receptor subfamily 1 group I member 2target
HexestrolNuclear receptor subfamily 1 group I member 3target
NocodazoleHematopoietic prostaglandin D synthasetarget
Puromycin60S ribosomal protein L10-liketarget
Puromycin60S ribosomal protein L13atarget
Puromycin60S ribosomal protein L23target
Puromycin60S ribosomal protein L15target
Puromycin60S ribosomal protein L19target
Puromycin60S ribosomal protein L23atarget
PuromycinProbable ribosome biogenesis protein RLP24target
Puromycin60S ribosomal protein L26-like 1target
Puromycin60S ribosomal protein L8target
Puromycin60S ribosomal protein L37target
Puromycin60S ribosomal protein L3target
Puromycin60S ribosomal protein L11target
PuromycinLeucyl/phenylalanyl-tRNA--protein transferasetarget
FormestaneCytochrome P450 3A4enzyme
FlumequineCytochrome P450 1A2enzyme
SiltuximabInterleukin-6target
SiltuximabCytochrome P450 3A4enzyme
DienogestCytochrome P450 3A4enzyme
DienogestProgesterone receptortarget
DienogestAndrogen receptortarget
NiguldipineAlpha-1A adrenergic receptortarget
NiguldipineCytochrome P450 3A4enzyme
NiguldipineP-glycoprotein 1transporter
CurcuminPeroxisome proliferator-activated receptor gammatarget
CurcuminVitamin D3 receptortarget
CurcuminMultidrug resistance-associated protein 5target
CurcuminCarbonyl reductase [NADPH] 1target
CurcuminGlutathione S-transferase Ptarget
CurcuminCytochrome P450 2C9enzyme
CurcuminCytochrome P450 3A4enzyme
CurcuminCytochrome P450 2B6enzyme
CurcuminCytochrome P450 1A2enzyme
CurcuminCytochrome P450 2D6enzyme
CurcuminGlutathione S-transferase A1enzyme
CurcuminGlutathione S-transferase Mu 1enzyme
CurcuminGlutathione S-transferase Penzyme
CurcuminP-glycoprotein 1transporter
Bryostatin 1Cytochrome P450 3A4enzyme
Bryostatin 1Protein kinase C alpha typetarget
Bryostatin 1Protein kinase C epsilon typetarget
Bryostatin 1Caspase-8target
Bryostatin 1Protein unc-13 homolog Btarget
Bryostatin 1Serine/threonine-protein kinase D1target
Bryostatin 1T-lymphocyte activation antigen CD86target
Bryostatin 1Prostaglandin G/H synthase 2target
Bryostatin 1G1/S-specific cyclin-D1target
Bryostatin 1Tumor necrosis factortarget
TalazoparibPoly [ADP-ribose] polymerase 1target
TalazoparibPoly [ADP-ribose] polymerase 2target
TalazoparibP-glycoprotein 1transporter
TalazoparibATP-binding cassette sub-family G member 2transporter
TremelimumabCytotoxic T-lymphocyte protein 4target
NiraparibPoly [ADP-ribose] polymerase 1target
NiraparibPoly [ADP-ribose] polymerase 2target
NiraparibCarboxylesteraseenzyme
NiraparibBeta-glucuronidaseenzyme
SaracatinibCytochrome P450 3A4enzyme
6-O-benzylguanineCytochrome P450 3A4enzyme
CarboxyamidotriazoleCytochrome P450 3A4enzyme
Epigallocatechin gallateAryl hydrocarbon receptortarget
Epigallocatechin gallateDNA (cytosine-5)-methyltransferase 1target
Epigallocatechin gallateDihydrofolate reductase, mitochondrialtarget
EpofolateCytochrome P450 3A4enzyme
RucaparibPoly [ADP-ribose] polymerase 1target
RucaparibPoly [ADP-ribose] polymerase 2target
RucaparibPoly [ADP-ribose] polymerase 3target
RucaparibCytochrome P450 2D6enzyme
RucaparibCytochrome P450 1A2enzyme
RucaparibCytochrome P450 3A4enzyme
RucaparibP-glycoprotein 1transporter
RucaparibATP-binding cassette sub-family G member 2transporter
RucaparibMultidrug and toxin extrusion protein 1transporter
RucaparibMultidrug and toxin extrusion protein 2transporter
RucaparibSolute carrier family 22 member 1transporter
RucaparibMultidrug resistance-associated protein 4transporter
RucaparibSolute carrier organic anion transporter family member 1B1transporter
RucaparibSolute carrier organic anion transporter family member 1B3transporter
RucaparibSolute carrier family 22 member 6transporter
RucaparibSolute carrier family 22 member 8transporter
RucaparibCytochrome P450 3A5enzyme
RucaparibCytochrome P450 3A7enzyme
RucaparibCytochrome P450 3A43enzyme
RucaparibCytochrome P450 2C19enzyme
RucaparibCytochrome P450 2C9enzyme
RucaparibCytochrome P450 2C8enzyme
RucaparibUDP-glucuronosyltransferase 1-1enzyme
NavitoclaxApoptosis regulator Bcl-2target
NavitoclaxBcl-2-like protein 2target
NavitoclaxBcl2 antagonist of cell deathtarget
IndirubinCytochrome P450 1A1target
IndirubinAryl hydrocarbon receptortarget
9-aminocamptothecinCytochrome P450 3A4enzyme
OnapristoneGlucocorticoid receptortarget
OnapristoneProbable G-protein coupled receptor 133target
Phenethyl IsothiocyanateActin, aortic smooth muscletarget
Phenethyl IsothiocyanateActin, cytoplasmic 1target
Phenethyl IsothiocyanateATP synthase subunit beta, mitochondrialtarget
Phenethyl IsothiocyanateATP synthase subunit e, mitochondrialtarget
Phenethyl IsothiocyanateATP synthase subunit g, mitochondrialtarget
Phenethyl IsothiocyanateCytochrome b5 type Btarget
Phenethyl IsothiocyanateDiablo homolog, mitochondrialtarget
Phenethyl IsothiocyanateF-box only protein 41target
Phenethyl IsothiocyanateHeterogeneous nuclear ribonucleoprotein Ftarget
Phenethyl IsothiocyanateHeterogeneous nuclear ribonucleoprotein Ktarget
Phenethyl IsothiocyanateHeat shock 70 kDa protein 4target
Phenethyl IsothiocyanateHeat shock protein beta-1target
Phenethyl Isothiocyanate10 kDa heat shock protein, mitochondrialtarget
Phenethyl IsothiocyanateHeat shock protein 105 kDatarget
Phenethyl IsothiocyanateNADH-ubiquinone oxidoreductase chain 1target
Phenethyl IsothiocyanateNuclear migration protein nudCtarget
Phenethyl IsothiocyanatePappalysin-1target
Phenethyl IsothiocyanateProteasome subunit alpha type-3target
Phenethyl Isothiocyanate26S protease regulatory subunit 6Atarget
Phenethyl IsothiocyanateRan-specific GTPase-activating proteintarget
Phenethyl IsothiocyanateProtein S100-A10target
Phenethyl IsothiocyanateSplicing factor 3A subunit 3target
Phenethyl IsothiocyanateSWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily E member 1target
Phenethyl IsothiocyanateSuccinyl-CoA ligase [GDP-forming] subunit beta, mitochondrialtarget
Phenethyl IsothiocyanateTumor protein D54target
Phenethyl IsothiocyanateTropomyosin alpha-1 chaintarget
Phenethyl IsothiocyanateTropomyosin alpha-3 chaintarget
Phenethyl IsothiocyanateTropomyosin alpha-4 chaintarget
Phenethyl IsothiocyanateTubulin alpha-1A chaintarget
Phenethyl IsothiocyanateTubulin alpha-3C/D chaintarget
Phenethyl IsothiocyanateTubulin alpha-4A chaintarget
Phenethyl IsothiocyanateTubulin beta-1 chaintarget
Phenethyl IsothiocyanateTubulin beta-2A chaintarget
Phenethyl IsothiocyanateTubulin beta-3 chaintarget
Phenethyl IsothiocyanateTubulin beta-4B chaintarget
Phenethyl IsothiocyanateThioredoxintarget
Phenethyl IsothiocyanateUbiquitin carboxyl-terminal hydrolase isozyme L1target
Phenethyl IsothiocyanateUbiquitin carboxyl-terminal hydrolase 14target
Phenethyl IsothiocyanateTransitional endoplasmic reticulum ATPasetarget
Phenethyl IsothiocyanateVimentintarget
Phenethyl Isothiocyanate14-3-3 protein beta/alphatarget
Phenethyl Isothiocyanate14-3-3 protein epsilontarget
Phenethyl Isothiocyanate14-3-3 protein etatarget
Phenethyl Isothiocyanate14-3-3 protein thetatarget
Phenethyl Isothiocyanate14-3-3 protein zeta/deltatarget
LometrexolDihydrofolate reductasetarget
HypericinSerum albumincarrier
HypericinGlutathione S-transferase A1target
HypericinGlutathione S-transferase Ptarget
NedaplatinGlutathionetarget
NedaplatinDNAtarget
Oxolinic acidCytochrome P450 1A2enzyme
IniparibPoly [ADP-ribose] polymerase 1target
TretamineCholinesteraseenzyme
MasoprocolArachidonate 5-lipoxygenasetarget
MasoprocolArachidonate 5-lipoxygenaseenzyme
MasoprocolSex hormone-binding globulintarget
AnagrelidecGMP-inhibited 3',5'-cyclic phosphodiesterase Atarget
AnagrelideCytochrome P450 1A2enzyme
Aminolevulinic acidDelta-aminolevulinic acid dehydratasetarget
Aminolevulinic acidSolute carrier family 15 member 1transporter
Aminolevulinic acidSolute carrier family 15 member 2transporter
IxabepiloneTubulin beta-3 chaintarget
IxabepiloneCytochrome P450 3A4enzyme
IxabepiloneP-glycoprotein 1transporter
VintafolideFolate receptor betatarget
VintafolideFolate receptor gammatarget
VintafolideFolate receptor alphatarget
RidaforolimusSerine/threonine-protein kinase mTORtarget
RidaforolimusCytochrome P450 3A4enzyme
PralatrexateFolylpolyglutamate synthase, mitochondrialenzyme
PralatrexateDihydrofolate reductasetarget
PralatrexateThymidylate synthasetarget
PralatrexateFolate transporter 1transporter
PralatrexateCanalicular multispecific organic anion transporter 1transporter
PralatrexateATP-binding cassette sub-family G member 2transporter
EfaproxiralHemoglobin subunit alphatarget
EfaproxiralHemoglobin subunit betatarget
CabozantinibCytochrome P450 3A4enzyme
CabozantinibCytochrome P450 2C9enzyme
CabozantinibHepatocyte growth factor receptortarget
CabozantinibVascular endothelial growth factor receptor 2target
CabozantinibProto-oncogene tyrosine-protein kinase receptor Rettarget
CabozantinibCytochrome P450 2C8enzyme
DinutuximabGanglioside GD2target
SonidegibSmoothened homologtarget
SonidegibCytochrome P450 3A4enzyme
VinflunineATP-binding cassette sub-family B member 5transporter
VinflunineP-glycoprotein 1transporter
VinflunineSerum albumincarrier
Vinfluninealpha1-acid glycoproteincarrier
VinflunineCytochrome P450 3A4enzyme
VinflunineTubulin beta chaintarget
Interferon alfa-2bInterferon alpha/beta receptor 2target
Interferon alfa-2bInterferon alpha/beta receptor 1target
Interferon alfa-2bCytochrome P450 1A2enzyme
CobimetinibDual specificity mitogen-activated protein kinase kinase 1target
CobimetinibCytochrome P450 3A4enzyme
CobimetinibP-glycoprotein 1enzyme
CobimetinibSolute carrier organic anion transporter family member 1B1transporter
CobimetinibSolute carrier organic anion transporter family member 1B3transporter
CobimetinibATP-binding cassette sub-family G member 2transporter
CobimetinibP-glycoprotein 1transporter
Inotuzumab ozogamicinP-glycoprotein 1transporter
Inotuzumab ozogamicinB-cell receptor CD22target
OlaratumabPlatelet-derived growth factor receptor alphatarget
ElotuzumabSLAM family member 7target
DegarelixGonadotropin-releasing hormone receptortarget
BuserelinLutropin-choriogonadotropic hormone receptortarget
BuserelinGonadotropin-releasing hormone receptortarget
BuserelinCytochrome P450 19A1enzyme
Asparaginase Erwinia chrysanthemiThyroxine-binding globulincarrier
EnzalutamideSerum albumincarrier
EnzalutamideCytochrome P450 2C8enzyme
EnzalutamideCytochrome P450 3A4enzyme
EnzalutamideAndrogen receptortarget
EnzalutamideCytochrome P450 2C9enzyme
EnzalutamideCytochrome P450 2C19enzyme
EnzalutamideCytochrome P450 2B6enzyme
EnzalutamideCytochrome P450 3A5enzyme
EnzalutamideP-glycoprotein 1transporter
EnzalutamideThyroxine-binding globulincarrier
AlectinibALK tyrosine kinase receptortarget
AlectinibATP-binding cassette sub-family G member 2transporter
AlectinibP-glycoprotein 1transporter
VenetoclaxApoptosis regulator Bcl-2target
VenetoclaxCytochrome P450 3A4enzyme
VenetoclaxP-glycoprotein 1transporter
VenetoclaxATP-binding cassette sub-family G member 2transporter
VenetoclaxSolute carrier organic anion transporter family member 1B1transporter
AtezolizumabProgrammed cell death 1 ligand 1target
DurvalumabProgrammed cell death 1 ligand 1target
RibociclibCyclin-dependent kinase 4target
RibociclibCyclin-dependent kinase 6target
RibociclibCytochrome P450 3A4enzyme
AvelumabProgrammed cell death 1 ligand 1target
GenisteinEstrogen receptor betatarget
GenisteinDNA topoisomerase 2-alphatarget
GenisteinProtein-tyrosine kinase 2-betatarget
GenisteinP-glycoprotein 1transporter
GenisteinMultidrug resistance-associated protein 1transporter
GenisteinATP-binding cassette sub-family G member 2transporter
GenisteinCytochrome P450 1A2enzyme
GenisteinNuclear receptor coactivator 1target
GenisteinEstrogen receptor alphatarget
GenisteinNuclear receptor coactivator 2target
GenisteinTransthyretincarrier
GenisteinSteroid hormone receptor ERR2target
GenisteinSteroid hormone receptor ERR1target
GenisteinNuclear receptor subfamily 1 group I member 2target
GenisteinRAC-alpha serine/threonine-protein kinasetarget
GenisteinG-protein coupled estrogen receptor 1target
GenisteinCytochrome P450 1B1target
GenisteinSex hormone-binding globulintarget
GenisteinCytochrome P450 1A1enzyme
GenisteinSolute carrier organic anion transporter family member 1B1transporter
GenisteinSolute carrier organic anion transporter family member 2B1transporter
GenisteinCytochrome P450 2C8enzyme
GenisteinCytochrome P450 2C9enzyme
GenisteinCytochrome P450 3A1enzyme
GenisteinCytochrome P450 3A2enzyme
GenisteinCytochrome P450 3A4enzyme
TrifluridineThymidylate synthasetarget
TrifluridineDNAtarget
TrifluridineThymidine kinase, cytosolicenzyme
TrifluridineThymidine phosphorylaseenzyme
TrifluridineSolute carrier family 22 member 6transporter
TrifluridineSodium/nucleoside cotransporter 1transporter
TrifluridineEquilibrative nucleoside transporter 1transporter
TrifluridineEquilibrative nucleoside transporter 2transporter
TrifluridineSerum albumincarrier
PracinostatHistone deacetylase 1target
PracinostatHistone deacetylase 2target
PracinostatHistone deacetylase 3target
PracinostatHistone deacetylase 6target
MocetinostatHistone deacetylase 1target
MocetinostatHistone deacetylase 3target
MocetinostatHistone deacetylase 2target
AbexinostatHistone deacetylase 1target
Valproic acidHistone deacetylase 9target
Valproic acidShort/branched chain specific acyl-CoA dehydrogenase, mitochondrialtarget
Valproic acidCytochrome P450 2A6enzyme
Valproic acidCytochrome P450 2B6enzyme
Valproic acidCytochrome P450 2C9enzyme
Valproic acidSolute carrier family 22 member 5transporter
Valproic acidSolute carrier family 22 member 6transporter
Valproic acidSolute carrier family 22 member 8transporter
Valproic acidMonocarboxylate transporter 1transporter
Valproic acidSolute carrier family 22 member 7transporter
Valproic acidCytochrome P450 3A5enzyme
Valproic acidUDP-glucuronosyltransferase 1-9enzyme
Valproic acidProstaglandin G/H synthase 1enzyme
Valproic acidCytochrome P450 1A2enzyme
Valproic acidCytochrome P450 2C19enzyme
Valproic acidCytochrome P450 3A4enzyme
Valproic acidUDP-glucuronosyltransferase 1-4enzyme
Valproic acidUDP-glucuronosyltransferase 1-8enzyme
Valproic acidUDP-glucuronosyltransferase 1-10enzyme
Valproic acidUDP-glucuronosyltransferase 1-6enzyme
Valproic acidUDP-glucuronosyltransferase 1-3enzyme
Valproic acidUDP-glucuronosyltransferase 2B7enzyme
Valproic acidUDP-glucuronosyltransferase 2B15enzyme
Valproic acid2-oxoglutarate dehydrogenase, mitochondrialtarget
Valproic acidSuccinate-semialdehyde dehydrogenase, mitochondrialtarget
Valproic acidSodium channel proteintarget
Valproic acidHistone deacetylase 2target
Valproic acidPeroxisome proliferator-activated receptor alphatarget
Valproic acidPeroxisome proliferator-activated receptor deltatarget
Valproic acidPeroxisome proliferator-activated receptor gammatarget
Valproic acidSerum albumincarrier
Valproic acidUDP-glucuronosyltransferase 1-1enzyme
Valproic acidSolute carrier organic anion transporter family member 2B1transporter
BufexamacProstaglandin G/H synthase 1target
BufexamacProstaglandin G/H synthase 2target
BufexamacHistone deacetylase 6target
BufexamacHistone deacetylase 10target
TetrandrineP-glycoprotein 1target
TetrandrineCytochrome P450 3A4enzyme
TetrandrineP-glycoprotein 1transporter
DofequidarATP-binding cassette sub-family B member 5target
DofequidarP-glycoprotein 1target
DofequidarP-glycoprotein 1transporter
DexniguldipineP-glycoprotein 1target
DexniguldipineCytochrome P450 3A4enzyme
AldoxorubicinDNA topoisomerase 2-alphatarget
Peginterferon alfa-2aInterferon alpha/beta receptor 2target
Peginterferon alfa-2aInterferon alpha/beta receptor 1target
Peginterferon alfa-2aCytochrome P450 1A2enzyme
Methylprednisolone hemisuccinateCytochrome P450 3A4enzyme
Methylprednisolone hemisuccinateCytochrome P450 3A5enzyme
Prednisone acetateCytochrome P450 3A4enzyme
Prednisone acetateCytochrome P450 3A5enzyme
Moxetumomab PasudotoxB-cell receptor CD22target
Moxetumomab PasudotoxElongation factor 2target
DacomitinibCytochrome P450 2D6enzyme
DacomitinibSerum albumincarrier
DacomitinibCytochrome P450 3A4enzyme
DacomitinibCytochrome P450 2C9enzyme
DacomitinibUDP-glucuronosyltransferase 1-1enzyme
DacomitinibP-glycoprotein 1transporter
DacomitinibATP-binding cassette sub-family G member 2transporter
DacomitinibSolute carrier family 22 member 1transporter
DacomitinibEpidermal growth factor receptortarget
BrequinarDihydroorotate dehydrogenase (quinone), mitochondrialtarget
PiritreximDihydrofolate reductasetarget
7-ethyl-10-hydroxycamptothecinDNA topoisomerase 1target
7-ethyl-10-hydroxycamptothecinCytochrome P450 3A4enzyme
TNP-470Methionine aminopeptidase 2target
GilteritinibSerum albumincarrier
GilteritinibCytochrome P450 3A4enzyme
GilteritinibReceptor-type tyrosine-protein kinase FLT3target
GilteritinibSerotonin Receptorstarget
GilteritinibP-glycoprotein 1transporter
GilteritinibMultidrug and toxin extrusion protein 1transporter
GilteritinibATP-binding cassette sub-family G member 2transporter
GilteritinibSolute carrier family 22 member 1transporter
GilteritinibTyrosine-protein kinase receptor UFOtarget
GilteritinibALK tyrosine kinase receptortarget
TagraxofuspInterleukin-3 receptor subunit alphatarget
TagraxofuspADP-ribosylation factor-like protein 2target
VadimezanUDP-glucuronosyltransferase 1-9enzyme
VadimezanUDP-glucuronosyltransferase 2B7enzyme
VadimezanCytochrome P450 1A2enzyme
GlasdegibCytochrome P450 3A4enzyme
GlasdegibSmoothened homologtarget
GlasdegibCytochrome P450 2C8enzyme
GlasdegibUDP-glucuronosyltransferase 1-9enzyme
GlasdegibSerum albumincarrier
GlasdegibP-glycoprotein 1transporter
GlasdegibATP-binding cassette sub-family G member 2transporter
GlasdegibMultidrug and toxin extrusion protein 1transporter
GlasdegibMultidrug and toxin extrusion protein 2transporter
PlitidepsinCytochrome P450 3A4enzyme
PlitidepsinCytochrome P450 2A6enzyme
PlitidepsinCytochrome P450 2E1enzyme
PlitidepsinCytochrome P450 4A11enzyme
EncorafenibCytochrome P450 3A4enzyme
EncorafenibCytochrome P450 2C19enzyme
EncorafenibCytochrome P450 2D6enzyme
EncorafenibSerine/threonine-protein kinase B-raftarget
EncorafenibG1/S-specific cyclin-D1target
IcotinibEpidermal growth factor receptortarget
IcotinibCytochrome P450 3A4enzyme
IcotinibCytochrome P450 1A2enzyme
IcotinibCytochrome P450 3A5enzyme
NeratinibCytochrome P450 3A4enzyme
NeratinibDimethylaniline monooxygenase [N-oxide-forming] 3enzyme
NeratinibP-glycoprotein 1transporter
NeratinibEpidermal growth factor receptortarget
NeratinibSerum albumincarrier
Neratinibalpha1-acid glycoproteincarrier
BinimetinibInterleukin-6target
BinimetinibTumor necrosis factortarget
BinimetinibInterleukin-1 betatarget
BinimetinibUDP-glucuronosyltransferase 1-1enzyme
BinimetinibCytochrome P450 1A2enzyme
BinimetinibCytochrome P450 2C19enzyme
BinimetinibMitogen-activated protein kinase kinase kinase 1target
BinimetinibDual specificity mitogen-activated protein kinase kinase 2target
AbemaciclibMultidrug and toxin extrusion protein 1transporter
AbemaciclibMultidrug and toxin extrusion protein 2transporter
AbemaciclibCyclin-dependent kinase 4target
AbemaciclibCyclin-dependent kinase 6target
AbemaciclibSerum albumincarrier
Abemaciclibalpha1-acid glycoproteincarrier
AbemaciclibCytochrome P450 3A4enzyme
AbemaciclibP-glycoprotein 1transporter
AbemaciclibATP-binding cassette sub-family G member 2transporter
AbemaciclibSolute carrier family 22 member 2transporter
AbemaciclibCytochrome P450 1A2enzyme
AbemaciclibCytochrome P450 2B6enzyme
AbemaciclibCytochrome P450 2C8enzyme
AbemaciclibCytochrome P450 2C9enzyme
AbemaciclibCytochrome P450 2D6enzyme
LorlatinibALK tyrosine kinase receptortarget
LorlatinibCytochrome P450 3A Subfamilyenzyme
LorlatinibCytochrome P450 3A5enzyme
LorlatinibCytochrome P450 2B6enzyme
LorlatinibCytochrome P450 2C8enzyme
LorlatinibCytochrome P450 2C19enzyme
LorlatinibUDP-glucuronosyltransferase 1-3enzyme
BrigatinibALK tyrosine kinase receptortarget
BrigatinibEpidermal growth factor receptortarget
BrigatinibTyrosine-protein kinase ABL1target
BrigatinibInsulin-like growth factor 1 receptortarget
BrigatinibReceptor-type tyrosine-protein kinase FLT3target
BrigatinibCytochrome P450 2C8enzyme
BrigatinibCytochrome P450 3A4enzyme
BrigatinibInsulin receptortarget
BrigatinibHepatocyte growth factor receptortarget
BrigatinibReceptor tyrosine-protein kinase erbB-4target
BrigatinibReceptor tyrosine-protein kinase erbB-2target
BrigatinibATP-binding cassette sub-family B member 5transporter
BrigatinibATP-binding cassette sub-family G member 2transporter
BrigatinibSolute carrier family 22 member 1transporter
BrigatinibMultidrug and toxin extrusion protein 1transporter
BrigatinibMultidrug and toxin extrusion protein 2transporter
BrigatinibCytochrome P450 3A Subfamilyenzyme
CopanlisibPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoformtarget
CopanlisibPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoformtarget
CopanlisibCytochrome P450 3A4enzyme
CopanlisibCytochrome P450 3A5enzyme
CopanlisibCytochrome P450 3A7enzyme
CopanlisibCytochrome P450 3A43enzyme
CopanlisibP-glycoprotein 1transporter
CopanlisibATP-binding cassette sub-family G member 2transporter
CopanlisibMultidrug and toxin extrusion protein 2transporter
CopanlisibSerum albumincarrier
MogamulizumabC-C chemokine receptor type 4target
OlmutinibEpidermal growth factor receptortarget
EnasidenibCytochrome P450 1A2enzyme
EnasidenibCytochrome P450 2B6enzyme
EnasidenibIsocitrate dehydrogenase [NADP], mitochondrialtarget
EnasidenibCytochrome P450 2C8enzyme
EnasidenibCytochrome P450 2C9enzyme
EnasidenibCytochrome P450 2C19enzyme
EnasidenibCytochrome P450 2D6enzyme
EnasidenibCytochrome P450 3A4enzyme
EnasidenibUDP-glucuronosyltransferase 1-1enzyme
EnasidenibUDP-glucuronosyltransferase 1-3enzyme
EnasidenibUDP-glucuronosyltransferase 1-4enzyme
EnasidenibUDP-glucuronosyltransferase 1-9enzyme
EnasidenibUDP-glucuronosyltransferase 2B7enzyme
EnasidenibUDP-glucuronosyltransferase 2B15enzyme
EnasidenibP-glycoprotein 1transporter
EnasidenibATP-binding cassette sub-family G member 2transporter
EnasidenibSolute carrier family 22 member 6transporter
EnasidenibSolute carrier organic anion transporter family member 1B1transporter
EnasidenibSolute carrier family 22 member 2transporter
EnasidenibSolute carrier organic anion transporter family member 1B3transporter
EnasidenibSolute carrier family 22 member 8transporter
Talimogene laherparepvecHeparan sulfatetarget
Talimogene laherparepvecDNA polymerase catalytic subunittarget
Talimogene laherparepvecDNA polymerase catalytic subunittarget
ErdafitinibCytochrome P450 2C9enzyme
ErdafitinibCytochrome P450 3A4enzyme
ErdafitinibFibroblast growth factor receptor 1target
ErdafitinibFibroblast growth factor receptor 2target
ErdafitinibFibroblast growth factor receptor 3target
ErdafitinibFibroblast growth factor receptor 4target
ErdafitinibP-glycoprotein 1transporter
ErdafitinibSolute carrier family 22 member 2transporter
ErdafitinibRET proto-oncogenetarget
ErdafitinibMacrophage colony-stimulating factor 1 receptortarget
ErdafitinibPlatelet-derived growth factor receptor alphatarget
ErdafitinibPlatelet-derived growth factor receptor betatarget
ErdafitinibMast/stem cell growth factor receptor Kittarget
ErdafitinibVascular endothelial growth factor receptor 2target
ApalutamideAndrogen receptortarget
ApalutamideCytochrome P450 3A4enzyme
ApalutamideCytochrome P450 2C8enzyme
ApalutamideCytochrome P450 2C19enzyme
ApalutamideCytochrome P450 2C9enzyme
ApalutamideP-glycoprotein 1transporter
ApalutamideATP-binding cassette sub-family G member 2transporter
ApalutamideSolute carrier organic anion transporter family member 1B1transporter
ApalutamideSolute carrier family 22 member 2transporter
ApalutamideSolute carrier family 22 member 8transporter
ApalutamideMultidrug and toxin extrusion protein 2transporter
ApalutamideGABA(A) Receptortarget
ApalutamideMultidrug and toxin extrusion protein 1transporter
AlpelisibPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoformtarget
AlpelisibCytochrome P450 3A4enzyme
AlpelisibCytochrome P450 2C9enzyme
AlpelisibCytochrome P450 2C8enzyme
AlpelisibCytochrome P450 2C19enzyme
AlpelisibATP-binding cassette sub-family G member 2transporter
AlpelisibP-glycoprotein 1transporter
TubercidinPurine nucleoside phosphorylase DeoD-typetarget
TrimetrexateDihydrofolate reductasetarget
TrimetrexateDihydrofolate reductaseenzyme
TrimetrexateFolate transporter 1transporter
Epothilone DTubulin alpha-3C/D chaintarget
Epothilone DTubulin beta chaintarget
Epothilone DTubulin beta-1 chaintarget
Epothilone DTubulin beta-4B chaintarget
Epothilone DTubulin beta-4A chaintarget
Epothilone DTubulin alpha-4A chaintarget
Epothilone DTubulin beta-3 chaintarget
Epothilone DTubulin alpha-1C chaintarget
Epothilone DTubulin alpha-8 chaintarget
Epothilone DTubulin alpha-1B chaintarget
Epothilone DTubulin alpha-1A chaintarget
Epothilone DCytochrome P450 3A4enzyme
MonastrolKinesin-like protein KIF11target
GaliximabT-lymphocyte activation antigen CD80target
EpratuzumabB-cell receptor CD22target
OregovomabMucin-16target
BanoxantroneDNA topoisomerase 2-alphatarget
BanoxantroneCytochrome P450 3A4enzyme
BanoxantroneCytochrome P450 1A1enzyme
BanoxantroneCytochrome P450 2B6enzyme
LabetuzumabCarcinoembryonic antigen-related cell adhesion molecule 5target
RindopepimutEpidermal growth factor receptortarget
PelitinibEpidermal growth factor receptortarget
FarletuzumabFolate receptor alphatarget
CT-011Programmed cell death protein 1target
Glembatumumab vedotinTransmembrane glycoprotein NMBtarget
AV-412Epidermal growth factor receptortarget
AV-412Receptor tyrosine-protein kinase erbB-2target
FilanesibKinesin-like protein KIF11target
AtrasentanEndothelin-1 receptortarget
IndisulamCytochrome P450 2C9enzyme
IndisulamCytochrome P450 3A4enzyme
IndisulamCytochrome P450 2E1enzyme
IndisulamCytochrome P450 2D6enzyme
FinafloxacinDNA gyrase subunit Atarget
FinafloxacinDNA topoisomerase 4 subunit Atarget
FinafloxacinDNA topoisomerase 2-alphatarget
ArtesunateMalaria protein EXP-1target
ArtesunateCytochrome P450 2A6enzyme
ArtesunateUDP-glucuronosyltransferase 2B7enzyme
ArtesunateUDP-glucuronosyltransferase 1-9enzyme
ArtesunateATP-binding cassette sub-family G member 2transporter
ArtesunateP-glycoprotein 1transporter
ArtesunateSolute carrier organic anion transporter family member 1B1transporter
ArtesunateSolute carrier family 22 member 8transporter
ArtesunateSerum albumincarrier
SilibininSolute carrier family 22 member 6transporter
SilibininUDP-glucuronosyltransferase 1-1enzyme
SilibininSolute carrier organic anion transporter family member 1B1transporter
SilibininSolute carrier organic anion transporter family member 1B3transporter
SilibininSolute carrier organic anion transporter family member 2B1transporter
TesevatinibPro-epidermal growth factortarget
TesevatinibEphrin type-B receptor 4target
TesevatinibReceptor tyrosine-protein kinase erbB-2target
Lorvotuzumab mertansineCytochrome P450 3A4enzyme
ZalutumumabEpidermal growth factor receptortarget
SagopiloneCytochrome P450 3A4enzyme
DacetuzumabTumor necrosis factor receptor superfamily member 5target
IvosidenibIsocitrate dehydrogenase [NADP] cytoplasmictarget
IvosidenibCytochrome P450 3A4enzyme
IvosidenibCytochrome P450 2B6enzyme
IvosidenibCytochrome P450 2C9enzyme
IvosidenibCytochrome P450 2C8enzyme
IvosidenibSolute carrier family 22 member 8transporter
IvosidenibP-glycoprotein 1transporter
CemiplimabProgrammed cell death protein 1target
ZanubrutinibCytochrome P450 3A4enzyme
ZanubrutinibP-glycoprotein 1transporter
ZanubrutinibCytochrome P450 2B6enzyme
ZanubrutinibTyrosine-protein kinase BTKtarget
ZanubrutinibEpidermal growth factor receptortarget
ZanubrutinibReceptor tyrosine-protein kinase erbB-2target
ZanubrutinibReceptor tyrosine-protein kinase erbB-4target
ZanubrutinibTyrosine-protein kinase ITK/TSKtarget
ZanubrutinibCytoplasmic tyrosine-protein kinase BMXtarget
ZanubrutinibTyrosine-protein kinase JAK2target
ZanubrutinibTyrosine-protein kinase Tectarget
ZanubrutinibTyrosine-protein kinase Blktarget
ZanubrutinibTyrosine-protein kinase JAK3target
ZanubrutinibProtein-tyrosine kinase 6target
ZanubrutinibTyrosine-protein kinase Fgrtarget
ZanubrutinibTyrosine-protein kinase FRKtarget
ZanubrutinibTyrosine-protein kinase Lcktarget
ZanubrutinibTyrosine-protein kinase TXKtarget
ZanubrutinibCytochrome P450 3A Subfamilyenzyme
TallimustineDNAtarget
PexidartinibCytochrome P450 3A4enzyme
PexidartinibUDP-glucuronosyltransferase 1-4enzyme
PexidartinibMacrophage colony-stimulating factor 1 receptortarget
PexidartinibCytochrome P450 2B6enzyme
PexidartinibCytochrome P450 2C9enzyme
PexidartinibUDP-glucuronosyltransferase 1-1enzyme
PexidartinibMultidrug and toxin extrusion protein 1transporter
PexidartinibMultidrug and toxin extrusion protein 2transporter
PexidartinibSolute carrier organic anion transporter family member 1B1transporter
PexidartinibSolute carrier organic anion transporter family member 1B3transporter
PexidartinibSolute carrier organic anion transporter family member 2B1transporter
PexidartinibSerum albumincarrier
PexidartinibAlpha-1-acid glycoprotein 1carrier
PexidartinibMast/stem cell growth factor receptor Kittarget
PexidartinibReceptor-type tyrosine-protein kinase FLT3target
PexidartinibPlatelet-derived growth factor receptor betatarget
EntrectinibCytochrome P450 3A4enzyme
EntrectinibP-glycoprotein 1transporter
EntrectinibHigh affinity nerve growth factor receptortarget
EntrectinibBDNF/NT-3 growth factors receptortarget
EntrectinibNT-3 growth factor receptortarget
EntrectinibProto-oncogene tyrosine-protein kinase ROStarget
EntrectinibTyrosine-protein kinase JAK2target
EntrectinibActivated CDC42 kinase 1target
LarotrectinibCytochrome P450 3A4enzyme
LarotrectinibHigh affinity nerve growth factor receptortarget
LarotrectinibBDNF/NT-3 growth factors receptortarget
LarotrectinibNT-3 growth factor receptortarget
LarotrectinibP-glycoprotein 1transporter
LarotrectinibATP-binding cassette sub-family G member 2transporter
AcalabrutinibTyrosine-protein kinase BTKtarget
AcalabrutinibCytochrome P450 3A4enzyme
AcalabrutinibCytochrome P450 3A5enzyme
AcalabrutinibCytochrome P450 3A Subfamilyenzyme
AcalabrutinibSerum albumincarrier
Acalabrutinibalpha1-acid glycoproteincarrier
4-(dimethylamino)-N-[7-(hydroxyamino)-7-oxoheptyl]benzamideHistone deacetylase 8target
MIV-711Cathepsin Ktarget
Axicabtagene ciloleucelB-lymphocyte antigen CD19target
BropirimineDihydroneopterin aldolasetarget
LexacalcitolVitamin D3 receptortarget
DeacetoxyvinzolidineCalmodulintarget
Trichostatin AHistone deacetylase 8target
Trichostatin AAcetoin utilization proteintarget
Trichostatin AHistone deacetylase 7target
alpha,beta-Methyleneadenosine 5'-triphosphate2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinasetarget
alpha,beta-Methyleneadenosine 5'-triphosphatePantothenate synthetasetarget
alpha,beta-Methyleneadenosine 5'-triphosphateNH(3)-dependent NAD(+) synthetasetarget
alpha,beta-Methyleneadenosine 5'-triphosphateNicotinamide mononucleotide adenylyltransferase 3target
alpha,beta-Methyleneadenosine 5'-triphosphateAdenylate cyclasetarget
alpha,beta-Methyleneadenosine 5'-triphosphateNTPase P4target
alpha,beta-Methyleneadenosine 5'-triphosphateProbable lignin peroxidase LipJtarget
alpha,beta-Methyleneadenosine 5'-triphosphateCarbapenam-3-carboxylate synthasetarget
5'-S-methyl-5'-thioadenosineModification methylase RsrItarget
5'-S-methyl-5'-thioadenosineS-methyl-5'-thioadenosine phosphorylasetarget
IsatuximabADP-ribosyl cyclase 1target
PemigatinibCytochrome P450 3A4enzyme
PemigatinibFibroblast growth factor receptor 1target
PemigatinibFibroblast growth factor receptor 2target
PemigatinibFibroblast growth factor receptor 3target
PemigatinibFibroblast growth factor receptor 4target
PemigatinibP-glycoprotein 1transporter
PemigatinibATP-binding cassette sub-family G member 2transporter
PemigatinibSolute carrier family 22 member 2transporter
PemigatinibMultidrug and toxin extrusion protein 1transporter
DarolutamideCytochrome P450 3A4enzyme
DarolutamideUDP-glucuronosyltransferase 1-9enzyme
DarolutamideAndrogen receptortarget
DarolutamideATP-binding cassette sub-family G member 2transporter
DarolutamideP-glycoprotein 1transporter
DarolutamideSerum albumincarrier
DarolutamideProgesterone receptortarget
DarolutamideSolute carrier organic anion transporter family member 1B1transporter
DarolutamideSolute carrier organic anion transporter family member 1B3transporter
CapmatinibCytochrome P450 3A4enzyme
CapmatinibAldehyde oxidaseenzyme
CapmatinibHepatocyte growth factor receptortarget
CapmatinibP-glycoprotein 1transporter
CapmatinibMultidrug and toxin extrusion protein 1transporter
CapmatinibMultidrug and toxin extrusion protein 2transporter
CapmatinibCytochrome P450 1A2enzyme
CapmatinibATP-binding cassette sub-family G member 2transporter
SelpercatinibProto-oncogene tyrosine-protein kinase receptor Rettarget
SelpercatinibVascular endothelial growth factor receptor 1target
SelpercatinibVascular endothelial growth factor receptor 3target
SelpercatinibFibroblast growth factor receptor 1target
SelpercatinibFibroblast growth factor receptor 2target
SelpercatinibFibroblast growth factor receptor 3target
SelpercatinibCytochrome P450 3A4enzyme
SelpercatinibCytochrome P450 2C8enzyme
SelpercatinibCytochrome P450 3A Subfamilyenzyme
SelpercatinibP-glycoprotein 1transporter
SelpercatinibATP-binding cassette sub-family G member 2transporter
SelpercatinibMultidrug and toxin extrusion protein 1transporter
Incadronic acidFarnesyl pyrophosphate synthasetarget
Incadronic acidCaspase-3target
Incadronic acidCaspase-4target
Incadronic acidCaspase-7target
Brexucabtagene autoleucelB-lymphocyte antigen CD19target
SelinexorCytochrome P450 3A4enzyme
SelinexorSolute carrier organic anion transporter family member 1B3transporter
SelinexorExportin-1target
FedratinibP-glycoprotein 1transporter
FedratinibATP-binding cassette sub-family G member 2transporter
FedratinibSolute carrier organic anion transporter family member 1B1transporter
FedratinibSolute carrier organic anion transporter family member 1B3transporter
FedratinibPOU domain, class 2, transcription factor 2transporter
FedratinibMultidrug and toxin extrusion protein 1transporter
FedratinibMultidrug and toxin extrusion protein 2transporter
FedratinibCytochrome P450 3A4enzyme
FedratinibCytochrome P450 2C19enzyme
FedratinibDimethylaniline monooxygenase [N-oxide-forming] 3enzyme
FedratinibTyrosine-protein kinase JAK2target
FedratinibReceptor-type tyrosine-protein kinase FLT3target
FedratinibTyrosine-protein kinase JAK1target
FedratinibCytochrome P450 2D6enzyme
QuizartinibReceptor-type tyrosine-protein kinase FLT3target
PralsetinibProto-oncogene tyrosine-protein kinase receptor Rettarget
PralsetinibEpithelial discoidin domain-containing receptor 1target
PralsetinibNT-3 growth factor receptortarget
PralsetinibReceptor-type tyrosine-protein kinase FLT3target
PralsetinibTyrosine-protein kinase JAK1target
PralsetinibTyrosine-protein kinase JAK2target
PralsetinibHigh affinity nerve growth factor receptortarget
PralsetinibVascular endothelial growth factor receptor 2target
PralsetinibPlatelet-derived growth factor receptor betatarget
PralsetinibFibroblast growth factor receptor 1target
PralsetinibFibroblast growth factor receptor 2target
PralsetinibCytochrome P450 3A4enzyme
PralsetinibCytochrome P450 3A5enzyme
PralsetinibCytochrome P450 2D6enzyme
PralsetinibCytochrome P450 1A2enzyme
PralsetinibCytochrome P450 2C8enzyme
PralsetinibCytochrome P450 2C9enzyme
PralsetinibP-glycoprotein 1transporter
PralsetinibATP-binding cassette sub-family G member 2transporter
PralsetinibSolute carrier organic anion transporter family member 1B1transporter
PralsetinibSolute carrier organic anion transporter family member 1B3transporter
PralsetinibSolute carrier family 22 member 6transporter
PralsetinibMultidrug and toxin extrusion protein 1transporter
PralsetinibMultidrug and toxin extrusion protein 2transporter
PralsetinibBile salt export pumptransporter
TucatinibReceptor tyrosine-protein kinase erbB-2target
TucatinibATP-binding cassette sub-family G member 2transporter
TucatinibP-glycoprotein 1transporter
TucatinibSolute carrier family 22 member 2transporter
TucatinibMultidrug and toxin extrusion protein 1transporter
TucatinibMultidrug and toxin extrusion protein 2transporter
TucatinibCytochrome P450 2C8enzyme
TucatinibCytochrome P450 3A Subfamilyenzyme
TucatinibReceptor tyrosine-protein kinase erbB-2enzyme
TucatinibReceptor tyrosine-protein kinase erbB-3target