Antineoplastic Agents

All categories

Accession Number

DBCAT000024

Description

Substances that inhibit or prevent the proliferation of NEOPLASMS.

ATC Classification

Drugs

Drug	Drug Description
Cetuximab	An endothelial growth factor receptor binding fragment used to treat colorectal cancer as well as squamous cell carcinoma of the head and neck.
Denileukin diftitox	A recombinant cytotoxic protein based on a combination of diphtheria toxin fragments and interleukin-2 used to treat cutaneous T-cell lymphoma by targeting the interleukin-2 receptor.
Asparaginase Escherichia coli	An asparaginase enzyme from E. coli used as part of treatment regimens for acute lymphoblastic leukemias.
Pegaspargase	A modified form of L-asparagine amidohydrolase used to treat acute lymphoblastic leukemia, which is dependent on an external source of asparagine.
Trastuzumab	A monoclonal anti-human epidermal growth factor receptor 2 protein antibody used to treat HER2-positive breast, gastroesophageal, and gastric cancers.
Rituximab	A monoclonal anti-CD20 antibody used to treat non-Hodgkin's lymphoma, chronic lymphocytic leukemia, Wegener's granulomatosis, pemphigus vulgaris, and rheumatoid arthritis.
Bevacizumab	A monoclonal anti-vascular endothelial growth factor antibody used in combination with antineoplastic agents for the treatment of many types of cancer.
Bortezomib	A proteasome inhibitor used to treat multiple myeloma in patients who have not been successfully treated with at least two previous therapies.
Pipobroman	For the treatment of polycythaemia vera and refractory chronic myeloid leukaemia.
Cladribine	A purine antimetabolite used for the management of relapsing forms of Multiple Sclerosis (MS), used in patients who have not responded to or who were unable to tolerate alternative MS drugs.
Carmustine	An alkylating agent used in the treatment of various malignancies, including brain tumours and multiple myeloma, among others.
Amsacrine	A cytotoxic agent used to induce remission in acute adult leukemia that is not adequately responsive to other agents.
Bleomycin	A chemotherapy agent used to treat various malignancies, including head and neck malignancy, lymphoma, and testicular tumors, among others.
Chlorambucil	A chemotherapy agent used in the management of chronic lymphocytic leukemia and malignant lymphomas.
Raltitrexed	A folate analog thymidylate synthase inhibitor used in the treatment of advanced colorectal cancer.
Mitomycin	An antimetabolite used as an adjunct to ab externo (outside approach) eye surgeries for the treatment of glaucoma and used as a chemotherapeutic agent for various malignancies.
Bexarotene	A retinoid drug used for cutaneous manifestations of T-cell lymphoma in patients who have not responded well to previous systemic therapy.
Vindesine	A vinca alkaloid derived from vinblastine used for various types of malignancies, but mainly acute lymphocytic leukemia (ALL).
Gefitinib	A tyrosine kinase inhibitor used as first-line therapy to treat non-small cell lung carcinoma (NSCLC) that meets certain genetic mutation criteria.
Tioguanine	A purine analogue antineoplastic agent used for the induction of remission, and for remission consolidation in patients with acute nonlymphocytic anemias.
Vinorelbine	A vinca alkaloid used in the treatment of metastatic non-small cell lung carcinoma (NSLC) and in conjunction with other drugs in locally advanced NSCLC.
Valrubicin	An anthracycline used intravesically in the treatment of BCG-resistant bladder carcinoma.
Sorafenib	A kinase inhibitor used to treat unresectable liver carcinoma, advanced renal carcinoma, and differentiated thyroid carcinoma.
Streptozocin	A nitrosourea antineoplastic agent used in the treatment of metastatic pancreatic islet cell carcinoma.
Gemcitabine	A nucleoside metabolic inhibitor used as adjunct therapy in the treatment of certain types of ovarian cancer, non-small cell lung carcinoma, metastatic breast cancer, and as a single agent for pancreatic cancer.
Teniposide	A cytotoxic drug used as an adjunct for chemotherapy induction in the treatment of refractory childhood acute lymphoblastic leukemia.
Epirubicin	An anthracycline topoisomerase II inhibitor used as an adjuvant to treating axillary node metastases in patients who have undergone surgical resection of primary breast cancer.
Altretamine	An antineoplastic agent used in palliative treatment of persistent or recurrent ovarian cancer.
Cisplatin	A platinum based chemotherapy agent used to treat various sarcomas, carcinomas, lymphomas, and germ cell tumors.
Alitretinoin	A vitamin A derivative used to treat Kaposi's sarcoma and used off label to treat chronic hand eczema and psoriasis.
Oxaliplatin	A platinum based chemotherapy agent used to treat carcinoma of the colon or rectum or stage III colon cancer.
Erlotinib	An EGFR tyrosine kinase inhibitor used to treat certain small cell lung cancers or advanced metastatic pancreatic cancers.
Cyclophosphamide	A nitrogen mustard used to treat lymphomas, myelomas, leukemia, mycosis fungoides, neuroblastoma, ovarian adenocarcinoma, retinoblastoma, and breast carcinoma.
Vincristine	A vinca alkaloid used to treat acute leukemia, malignant lymphoma, Hodgkin's disease, acute erythraemia, and acute panmyelosis.
Fluorouracil	A pyrimidine analog used to treat basal cell carcinomas, and as an injection in palliative cancer treatment.
Pentostatin	An adenosine deaminase inhibitor used to treat hairy cell leukemia.
Methotrexate	An antineoplastic agent used the treatment of a wide variety of cancers as well as severe psoriasis, severe rheumatoid arthritis, and juvenile rheumatoid arthritis.
Vinblastine	A vinca alkaloid used to treat breast cancer, testicular cancer, neuroblastoma, Hodgkin's and non-Hodgkins lymphoma, mycosis fungoides, histiocytosis, and Kaposi's sarcoma.
Imatinib	A tyrosine kinase inhibitor used to treat a number of leukemias, myelodysplastic/myeloproliferative disease, systemic mastocytosis, hypereosinophilic syndrome, dermatofibrosarcoma protuberans, and gastrointestinal stromal tumors.
Clofarabine	A purine nucleoside used to treat relapsed or refractory acute lymphoblastic leukemia in patients 1 to 21 years old.
Pemetrexed	A folate analog used to treat mesothelioma and non-small cell lung cancer.
Mitotane	An adrenal cortex inhibitor used to treat adrenocortical tumors and Cushing's syndrome.
Daunorubicin	An anthracycline aminoglycoside used to induce remission of nonlymphocytic leukemia and acute lymphocytic leukemia.
Porfimer sodium	A hematoporphyrin derivative used to treat esophageal cancer, endobronchial cancer, and high grade dysplasia in Barrett's Esophagus.
Irinotecan	An antineoplastic enzyme inhibitor used to treat metastatic carcinoma of the colon or rectum.
Etoposide	A podophyllotoxin derivative used to treat testicular and small cell lung tumors.
Dacarbazine	An antineoplastic agent used to treat malignant melanoma and Hodgkin's disease.
Temozolomide	An alkylating agent used to treat glioblastoma multiforme and refractory anaplastic astrocytoma.
Mechlorethamine	An antineoplastic agent used to treat Hodgkin's disease, lymphosarcoma, and chronic myelocytic or lymphocytic leukemia.
Azacitidine	A pyrimidine nucleoside analogue used to treat certain subtypes of myelodysplastic syndrome.
Carboplatin	A alkylating agent used to treat advanced ovarian cancer.
Dactinomycin	An actinomycin used to treat a wide variety of cancers.
Cytarabine	A pyrimidine nucleoside analogue used to treat acute non-lymphocytic leukemia, lymphocytic leukemia, and the blast phase of chronic myelocytic leukemia.
Doxorubicin	A medication used to treat various cancers and Kaposi's Sarcoma.
Hydroxyurea	An antimetabolite used to treat sickle cell anemia crisis.
Busulfan	An alkylating agent used to treat chronic myelogenous leukemia.
Topotecan	An antineoplastic agent used to treat ovarian cancer, small cell lung cancer, or cervical cancer.
Mercaptopurine	An antineoplastic agent used to treat acute lymphocytic leukemia.
Melphalan	An alkylating antineoplastic agent used for high-dose conditioning prior to hematopoietic stem cell transplant in patients with multiple myeloma.
Fludarabine	A purine analog antimetabolite that inhibits DNA synthesis.
Capecitabine	A nucleoside metabolic inhibitor indicated to treat different gastrointestinal and breast cancer.
Procarbazine	An antineoplastic agent indicated for the treatment of stage III and stage IV Hodgkin's disease in combination with other chemotherapeutic agents.
Arsenic trioxide	A chemotherapeutic agent used in the treatment of refractory or relapsed acute promyelocytic leukemia in patients with prior retinoid and anthracycline chemotherapy.
Idarubicin	An anthracycline antineoplastic agent used to treat acute myeloid leukemia (AML) in adults.
Ifosfamide	An alkylating and immunosuppressive agent used in chemotherapy for the treatment of cancers, including testicular cancer, ovarian cancer, cervical cancer, osteocarcinoma, bladder cancer, small cell lung cancer, and non-Hodgkin's lymphoma.
Estramustine	An antineoplastic agent used for the management of metastatic and/or progressive prostate cancer in palliative setting.
Mitoxantrone	A chemotherapeutic agent used for the treatment of secondary progressive, progressive relapsing, or worsening relapsing-remitting multiple sclerosis.
Lomustine	An alkylating agent used as a part of chemotherapeutic regimens for the treatment of primary and metastatic brain tumors as well as refractory or relapsed Hodgkin's disease in addition to surgical and/or radiotherapeutic treatments.
Paclitaxel	A taxoid chemotherapeutic agent used as first-line and subsequent therapy for the treatment of advanced carcinoma of the ovary, and other various cancers including breast and lung cancer.
Docetaxel	A taxoid antineoplastic agent used in the treatment of various cancers, such as locally advanced or metastatic breast cancer, metastatic prostate cancer, gastric adenocarcinoma, and head and neck cancer.
Dasatinib	A tyrosine kinase inhibitor used for the treatment of lymphoblastic or chronic myeloid leukemia with resistance or intolerance to prior therapy.
Lapatinib	An antineoplastic agent and tyrosine kinase inhibitor used for the treatment of advanced or metastatic HER-positive breast cancer in patients who received prior chemotherapeutic treatments.
Decitabine	A chemotherapeutic pyrimidine nucleoside analogue used for the treatment of myelodysplastic syndromes (MDS) by inducing DNA hypomethylation and corresponding alterations in gene expression.
Sunitinib	A receptor tyrosine kinase inhibitor and chemotherapeutic agent used for the treatment of renal cell carcinoma (RCC) and imatinib-resistant gastrointestinal stromal tumor (GIST).
Panitumumab	A recombinant humanized monoclonal antibody used to treat EGFR-expressing, metastatic colorectal carcinoma that is refractory to fluoropyrimidine-, oxaliplatin-, and irinotecan- containing chemotherapy regimens.
Vorinostat	A histone deacetylase (HDAC) inhibitor used for the treatment of cutaneous manifestations in patients with progressive, persistent, or recurrent cutaneous T- cell lymphoma (CTCL) following prior systemic therapies.
Fotemustine	An alkylating agent used in the treatment of metastatic melanoma.
Thiotepa	An alkylating agent used to prevent graft rejection in stem cell transplantation and to treat a variety of malignancies including certain types of adenocarcinoma and superficial bladder carcinomas.
Omacetaxine mepesuccinate	A cephalotaxine used in the treatment of Chronic Myeloid Leukemia (CML) that is intolerant to or resistant to two or more tyrosine kinase inhibitors.
Satraplatin	Investigated for use/treatment in lung cancer, prostate cancer, and solid tumors.
Belinostat	A histone deacetylase (HDAC) inhibitor used for the treatment of patients with relapsed or refractory peripheral T-cell lymphoma (PTCL).
Trabectedin	An alkylating agent approved for the treatment of unresectable or metastatic soft tissue sarcoma (liposarcoma or leiomyosarcoma).
Ramucirumab	An antineoplastic agent and direct VEGFR2 (vascular endothelial growth factor receptor 2) antagonist that blocks the binding of natural VEGF ligands, which are secreted by solid tumors to promote angiogenesis and enhance tumor blood supply.
Trastuzumab emtansine	An antineoplastic agent and antibody-drug conjugate used to treat HER2-overexpressing breast cancer.
Romidepsin	A histone deacetylase (HDAC) inhibitor used to treat cutaneous T-cell lymphoma.
Pixantrone	An antineoplastic agent use to treat patients with relapsed or refractory aggressive Non-Hodgkin B-cell Lymphomas (NHL).
Amrubicin	Investigated for use/treatment in lung cancer .
Lonidamine	Investigated for use/treatment in benign prostatic hyperplasia, prostate disorders, and cancer/tumors (unspecified).
Temsirolimus	A antineoplastic agent used in the treatment of renal cell carcinoma (RCC) that works by inhibiting mTOR.
Pertuzumab	An antineoplastic agent used in the treatment of HER2-positive metastatic breast cancer in combination with other antineoplastic agents.
Panobinostat	A non-selective histone deacetylase inhibitor used to treat multiple myeloma in combination with other antineoplastic agents.
Bendamustine	An antineoplastic agent used for the treatment of chronic lymphocytic leukemia (CLL) and indolent B-cell non-Hodgkin lymphoma (NHL) that has progressed following rituximab therapy.
Plicamycin	For the treatment of testicular cancer, as well as hypercalcemia and hypercalciuria associated with a variety of advanced forms of cancer.
Ponatinib	A kinase inhibitor used to treat patients with various types of chronic myeloid leukemia (CML).
Trametinib	A kinase inhibitor used to treat patients with specific types of melanoma, non-small cell lung cancer, and thyroid cancer.
Dabrafenib	A kinase inhibitor used to treat patients with specific types of melanoma, non-small cell lung cancer, and thyroid cancer.
Obinutuzumab	An antineoplastic CD20 antibody used to treat untreated chronic lymphocytic leukemia in combination with chlorambucil.
Carmofur	Carmofur is a derivative of fluorouracil, and is an antineoplastic agent that has been used in the treatment of breast and colorectal cancer. Carmofur has been known to induce leukoencephalopathy.
Miltefosine	An antileishmanial agent used to treat leishmaniasis, a group of disease caused by parasites of the Leishmania type.
Nivolumab	A PD-1 blocking antibody used to treat melanoma, non small-cell lung cancer, renal cell cancer, head and neck cancer, and Hodgkin lymphoma.
Pembrolizumab	A PD-1 blocking antibody used to treat various types of cancer, including metastatic melanoma, non small-cell lung cancer, cervical cancer, head and neck cancer, and Hodgkin's lymphoma.
Blinatumomab	An antineoplastic antibody used to treat CD19-positive B-cell precursor acute lymphoblastic leukemia (ALL) in relapsed and refractory patients, as well as those in first or second complete remission with minimal residual disease (MRD).
Idelalisib	An antineoplastic kinase inhibitor used to treat chronic lymphocytic leukemia (CLL), relapsed follicular B-cell non-Hodgkin lymphoma (FL), and relapsed small lymphocytic lymphoma (SLL).
Ceritinib	An antineoplastic kinase inhibitor used to treat anaplastic lymphoma kinase (ALK)-positive metastatic non-small cell lung cancer (NSCLC) in patients with inadequate clinical response or intolerance to crizotinib.
Palbociclib	An endocrine-based chemotherapeutic agent used in combination with other antineoplastic agents to treat HER2-negative and HR-positive advanced or metastatic breast cancer.
Olaparib	A poly (ADP-ribose) polymerase (PARP) inhibitor used to treat ovarian cancer, breast cancer, pancreatic cancer, and prostate cancer.
Lenvatinib	A receptor tyrosine kinase inhibitor used for the treatment of metastatic thyroid cancer, advanced renal cell carcinoma in combination with everolimus, and unresectable hepatocellular carcinoma.
Nintedanib	A triple angiokinase inhibitor indicated for the treatment of idiopathic pulmonary fibrosis, systemic sclerosis-associated interstitial lung disease, and in combination with docetaxel for non-small cell lung cancer.
Tegafur	An antineoplastic agent used in combination with other anticancer medications to treat advanced gastric and colorectal cancers.
Ixazomib	A monoclonal antibody used with other medications to treat multiple myeloma in patients who have received one other therapy already.
Pirarubicin	Not Annotated
Aclarubicin	Not Annotated
Zorubicin	Zorubicin is a drug of the anthracycline class - a class of medications that have historically demonstrated effective chemotherapy for a variety of cancer types.
Temoporfin	A photosensitizer used to treat squamous cell carcinomas of the head and neck.
Prednimustine	Prednimustine has been used in trials studying the treatment of Lymphoma.
Trofosfamide	Trofosfamide has been used in trials studying the treatment of Ependymomas, Medulloblastomas, Sarcoma, Soft Tissue, Supratentorial PNETs, and Recurrent Brain Tumors.
Mitoguazone	Mitoguazone has been used in trials studying the treatment of Lymphoma, HIV Infections, and Lymphoma, Non-Hodgkin.
Nimustine	Nimustine has been used in trials studying the treatment of Glioblastoma.
Treosulfan	Treosulfan is under investigation in Allogeneic Haematopoietic Stem Cell Transplantation. Treosulfan has been investigated for the treatment of Lymphoblastic Leukemia, Acute, Childhood.
Cediranib	For the treatment of liver cancer, advanced non-small cell lung cancer (NSCLC), advanced colorectal cancer (CRC) and other solid tumors.
Gemtuzumab ozogamicin	A monoclonal anti-CD33 antibody used to treat CD33-positive acute myeloid leukemia.
Tiazofurine	Tiazofurine has potential clinical use in cancer treatment as it is a potential inhibitor of Inosine- 5’-monophosphate (IMP) dehydrogenase .
Triaziquone	Not Annotated
Demecolcine	Not Annotated
Etoglucid	Not Annotated
Mitobronitol	Not Annotated
Semustine	Not Annotated
Carboquone	Not Annotated
Ranimustine	Not Annotated
Leuprolide	A peptide-based GnRH receptor superagonist used for the palliative treatment of prostate cancer, uterine leiomyomata, endometriosis, and central precocious puberty.
Aldesleukin	A recombinant analog of interleukin-2 used to induce an adaptive immune response in the treatment of renal cell carcinoma.
Alemtuzumab	A monoclonal anti-CD52 antibody used in the treatment of B-cell chronic lymphocytic leukemia and relapsing forms of multiple sclerosis.
Megestrol acetate	A progestin that is administered orally to treat anorexia and cachexia or serious unexplained weight loss and is also used as an antineoplastic agent to treat certain types of malignancy.
Lenalidomide	A thalidomide derivative used to treat multiple myeloma and anemia in low to intermediate risk myelodysplastic syndrome.
Flutamide	An antiandrogen used for locally confined stage B2-C and D-2 metastatic prostate carcinoma.
Nilutamide	An antineoplastic hormone used to treat prostate cancer.
Tamoxifen	A selective estrogen receptor modulator used to treat estrogen receptor positive breast cancer, reduce the risk of invasive breast cancer following surgery, or reduce the risk of breast cancer in high risk women.
Fulvestrant	An estrogen receptor antagonist used to treat HR+ breast cancer that may also be HER2-.
Exemestane	An aromatase inhibitor used to treat breast cancer in postmenopausal women after treatment with tamoxifen.
Letrozole	An aromatase inhibitor used to treat breast cancer in postmenopausal women.
Bicalutamide	An androgen receptor inhibitor used to treat Stage D2 metastatic carcinoma of the prostate.
Anastrozole	A competitive, selective, non-steroidal aromatase inhibitor used as adjuvant therapy for the treatment of hormone receptor-positive breast cancer in postmenopausal women.
Everolimus	A mammalian target of rapamycin (mTOR) kinase inhibitor used to treat various types of malignancies.
Nelarabine	A purine nucleoside analog and antineoplastic agent used for the treatment of with acute T-cell lymphoblastic leukemia and T-cell lymphoblastic lymphoma with inadequate clinical response to prior chemotherapeutic treatments.
Nilotinib	A kinase inhibitor used for the chronic phase treatment of Chronic Myeloid Leukemia (CML) that is Philadelphia chromosome positive and for the treatment of CML that is resistant to therapy containing imatinib.
Vandetanib	An antineoplastic kinase inhibitor used to treat symptomatic or progressive medullary thyroid cancer in patients with unresectable locally advanced or metastatic disease.
Ipilimumab	A human cytotoxic T-lymphocyte antigen 4 (CTLA-4) blocking antibody used to treat metastatic or unresectable melanoma.
Pazopanib	An antineoplastic agent used in the treatment of advanced renal cell cancer and advanced soft tissue sarcoma in patients with prior chemotherapy.
Catumaxomab	For use in the management of malignant ascites tumours via intraperitoneal infusion where standard therapy is not available or feasible [FDA Label].
Bosutinib	An antineoplastic agent used for the treatment of chronic, accelerated, or blast phase Philadelphia chromosome-positive (Ph+) chronic myelogenous leukemia (CML) in adults with inadequate clinical response to other treatments.
Axitinib	An oral VEGFR and kinase inhibitor used for the treatment of advanced renal cell carcinoma after failure of one prior systemic therapy.
Ofatumumab	An anti-CD20 antibody used for the treatment of chronic lymphocytic leukemia (CLL) in selected patients with certain treatment histories and responsiveness to anticancer medications.
Cabazitaxel	An antineoplastic agent used for the treatment of hormone-refractory metastatic prostate cancer previously treated with a docetaxel-containing treatment regimen.
Vismodegib	A hedgehog pathway inhibitor used to treat patients with locally advanced or metastatic basal cell carcinoma.
Crizotinib	A receptor tyrosine kinase inhibitor used to treat metastatic non-small cell lung cancer (NSCLC) where the tumors have been confirmed to be anaplastic lymphoma kinase (ALK), or ROS1-positive.
Brentuximab vedotin	A CD30-directed antibody-drug conjugate used to treat various types of lymphoma.
Eribulin	A microtubule inhibitor used to treat metastatic breast cancer and metastatic or unresectable liposarcoma.
Ruxolitinib	A kinase inhibitor used to treat various types of myelofibrosis, polycythemia vera in patients who have not responded to or cannot tolerate hydroxyurea, and to treat graft-versus-host disease in cases that are refractory to steroid treatment.
Vemurafenib	A kinase inhibitor used to treat patients with Erdheim-Chester Disease who have the BRAF V600 mutation, and melanoma in patients who have the BRAF V600E mutation.
Carfilzomib	A proteasome inhibitor used either alone or in conjunction with a chemotherapy regimen to treat patients with relapsed or refractory multiple myeloma.
Regorafenib	A kinase inhibitor used to treat patients with metastatic colorectal cancer, unresectable, locally advanced, or metastatic gastrointestinal stromal tumors, and hepatocellular carcinoma.
Afatinib	An antineoplastic agent used for the treatment of locally advanced or metastatic non-small cell lung cancer (NSCLC) with non-resistant EGFR mutations or resistance to platinum-based chemotherapy.
Ibrutinib	An antineoplastic agent used to treat chronic lymphocytic leukemia, mantle cell lymphoma, and Waldenstrom's Macroglobulinemia.
Necitumumab	A monoclonal antibody used to treat metastatic squamous non-small cell lung cancer.
Abiraterone	An antiandrogen used in the treatment of prostate cancer.
Midostaurin	An antineoplastic agent used to treat high-risk acute myeloid leukemia (AML) with specific mutations, aggressive systemic mastocytosis (ASM), systemic mastocytosis with associated hematologic neoplasm (SM-AHN), or mast cell leukemia (MCL).
Triptorelin	A GnRH agonist indicated for the palliative treatment of advanced prostate cancer.
Pomalidomide	A thalidomide analogue used in combination with dexamethasone to treat patients with multiple myeloma.
Osimertinib	A tyrosine kinase inhibitor used in the treatment of certain types of non-small cell lung carcinoma.
Daratumumab	A CD38-directed cytolytic antibody used alone or as an adjunct drug in the treatment of multiple myeloma and light chain amyloidosis.
Tretinoin	A vitamin A derivative used to treat acne vulgaris, certain types of promyelocytic leukemia, and fine wrinkles.
Goserelin	A synthetic analog of luteinizing hormone-releasing hormone used to treat breast cancer and prostate cancer by reducing secretion of gonadotropins from the pituitary.
Tositumomab	A monoclonal anti-CD20 antibody used to treat B-cell non-Hodgkin's lymphoma via a conjugated radioactive isotope.
Octreotide	A peptide drug used to treat acromegaly as well as diarrhea associated with metastatic carcinoid tumors and vasoactive intestinal peptide secreting tumors.
Cabergoline	A dopamine receptor agonist used for the treatment of hyperprolactinemic conditions due to various causes.
Chlorotrianisene	Used to treat symptoms of menopause, deficiencies in ovary function (including underdevelopment of female sexual characteristics and some types of infertility), and in rare cases, prostate cancer. Chlorotrianisene may also...
Pamidronic acid	A bisphosphonate used to treat Paget's disease, to treat hypercalcemia of malignancy, and to treat osteolytic bone lesions.
Floxuridine	An antimetabolite used as palliative management for liver metastases of gastrointestinal malignancy.
Aminoglutethimide	An adrenocortical steroid synthesis inhibitor used in the treatment of Cushing's syndrome.
Toremifene	A first generation nonsteroidal selective estrogen receptor modulator used to treat certain breast cancers.
Medroxyprogesterone acetate	A progestin used as a contraceptive and in the treatment of secondary amenorrhea, abnormal uterine bleeding, pain from endometriosis, endometrial and renal carcinomas, paraphilia in males, and GnRH-dependent precocious puberty.
Prednisone	A corticosteroid used to treat inflammation or immune-mediated reactions and to treat endocrine or neoplastic diseases.
Imiquimod	A toll-like receptor 7 agonist used to treat non hyperkeratotic, non hypertrophic actinic keratosis, basal cell carcinoma, genital or perianal warts, and condyloma acuminata.
Uracil mustard	Used for its antineoplastic properties.
Prednisolone	A glucocorticoid used to treat adrenocortical insufficiency, inflammatory conditions, and some cancers.
Testolactone	A medication used to treat advanced breast cancer.
Methylprednisolone	A corticosteroid used to treat inflammation or immune reactions across a variety of organ systems, endocrine conditions, and neoplastic diseases.
Thalidomide	A medication used to treat cancers, particularly newly diagnosed multiple myeloma, and erythema nodosum leprosum.
Trilostane	Used in the treatment of Cushing's syndrome. It is normally used in short-term treatment until permanent therapy is possible.
Dexamethasone	A glucocorticoid available in various modes of administration that is used for the treatment of various inflammatory conditions, including bronchial asthma, as well as endocrine and rheumatic disorders.
8-azaguanine	8-azaguanine is one of the early purine analogs showing antineoplastic activity. It functions as an antimetabolite and is easily incorporated into ribonucleic acids.
7-Hydroxystaurosporine	Not Available
Hadacidin	Not Available
2-Methoxyestradiol	For the treatment of breast cancer and inflammatory diseases such as rheumatoid arthritis.
Geldanamycin	Not Available
Fumagillin	Not Available
Patupilone	Investigated for use/treatment in ovarian cancer, lung cancer, brain cancer, breast cancer, and gastric cancer.
Sparfosic acid	Sparfosic acid is a solid. This compound belongs to the n-acyl-alpha amino acids. These are compounds containing an alpha amino acid which bears an acyl group at the terminal nitrogen...
Alvocidib	Investigated for use/treatment in esophageal cancer, leukemia (lymphoid), lung cancer, liver cancer, and lymphoma (unspecified).
2-(4-Chlorophenyl)-5-Quinoxalinecarboxamide	Not Available
Rhodamine 6G	Not Available
Batimastat	Not Available
3,4-Dihydroxybenzoic Acid	Not Available
Sparsomycin	An antitumor antibiotic produced by Streptomyces sparsogenes. It inhibits protein synthesis in 70S and 80S ribosomal systems. [PubChem]
Tretazicar	Tretazicar is under investigation in clinical trial NCT00746590 (Study of Anti-tumour Effects and Safety of Prolarix™ in Hepatocellular Carcinoma).
Seocalcitol	Not Available
Nebularine	Not Available
Afimoxifene	For the potential treatment of menstrual-cycle related mastalgia, fibrocystic breast disease, breast disease, gynecomastia and Keloid scarring.
Fleroxacin	Fleroxacin is a broad-spectrum antimicrobial fluoroquinolone.
Metoprine	Not Available
Camptothecin	Investigated for the treatment of cancer.
Suramin	For treatment of human sleeping sickness, onchocerciasis and other diseases caused by trypanosomes and worms.
Urethane	Urethane, formerly marketed as an inactive ingredient in Profenil injection, was determined to be carcinogenic and was removed from the Canadian, US, and UK markets in 1963.
Cyproterone acetate	A steroid used in combination with ethinyl estradiol to treat women with severe acne and symptoms of androgenization. Also used alone at much higher doses for palliative treatment of patients with prostate cancer
Tirapazamine	For the treatment of head and neck cancer.
Halofuginone	For the treatment of scleroderma, cancer, and restenosis.
Vapreotide	For the treatment of esophageal variceal bleeding in patients with cirrhotic liver disease and has also shown efficacy in the treatment of patients with AIDS-related diarrhea.
Thymalfasin	Indicated as an adjuvant for influenza vaccine in elderly patients and as an adjuvant for both influenza and hepatitis B vaccines in chronic hemodialysis patients who failed to achieve adequate...
Ranpirnase	For the treatment of various forms of cancer.
Pirfenidone	An agent used for the treatment of idiopathic pulmonary fibrosis (IPF).
Tipifarnib	Investigated for use/treatment in colorectal cancer, leukemia (myeloid), pancreatic cancer, and solid tumors.
Troxacitabine	Investigated for use/treatment in leukemia (myeloid).
Amonafide	Investigated for use/treatment in breast cancer, ovarian cancer, and prostate cancer.
Fenretinide	Investigated for use/treatment in macular degeneration.
Tetrathiomolybdate	Investigated for use/treatment in liver disease and pulmonary fibrosis.
Elsamitrucin	Investigated for use/treatment in lymphoma (non-hodgkin's).
Gallium nitrate	A medication indicated for cancer-related hypercalcemia.
Ecabet	For the treatment of reflux oesophagitis and peptic ulcer disease.
Canertinib	Investigated for use/treatment in breast cancer and lung cancer.
Motexafin gadolinium	Investigated for use/treatment in brain cancer, cancer/tumors (unspecified), lung cancer, and lymphoma (non-hodgkin's).
Alanosine	Investigated for use/treatment in brain cancer and cancer/tumors (unspecified).
Palifosfamide	Investigated for use/treatment in cancer/tumors (unspecified), lymphoma (unspecified), and sarcoma.
Trabedersen	Investigated for use/treatment in brain cancer, colorectal cancer, melanoma, and pancreatic cancer.
Oglufanide	Investigated for use/treatment in hepatitis (viral, C).
Irofulven	Investigated for use/treatment in brain cancer, breast cancer, endometrial cancer, liver cancer, lung cancer, ovarian cancer, pancreatic cancer, pediatric indications, prostate cancer, and sarcoma.
KOS-1584	Investigated for use/treatment in solid tumors.
Transcrocetinate	Investigated for use/treatment in cancer/tumors (unspecified), hemorrhage, hypoxia, respiratory failure, and strokes.
Rubitecan	Investigated for use/treatment in pancreatic cancer, leukemia (unspecified), melanoma, ovarian cancer, and cancer/tumors (unspecified).
Garenoxacin	Investigated for use/treatment in bacterial infection.
Plevitrexed	Investigated for use/treatment in pancreatic cancer, solid tumors, gastric cancer, lung cancer, and colorectal cancer.
Seliciclib	Investigated for use/treatment in breast cancer, lung cancer, lymphoma (unspecified), multiple myeloma, leukemia (lymphoid), and cancer/tumors (unspecified).
Eflornithine	A medication used topically to reduce unwanted facial hair growth in women. The postulated mechanism of action is through irreversible inhibition of ornithine decarboxylase (ODC) in the skin.
Exisulind	Investigated for use/treatment in adenomatous polyposis coli, lung cancer, prostate cancer, colon polyps, Barrett's esophagus disease, and pediatric indications.
Maxacalcitol	Not Annotated
Annamycin	Investigated for use/treatment in breast cancer and leukemia (unspecified).
Endostatin	Investigated for use/treatment in cancer/tumors (unspecified), macular degeneration, and diabetic retinopathy.
Tezacitabine	Investigated for use/treatment in colorectal cancer, lung cancer, leukemia (unspecified), and gastric cancer.
Semaxanib	Investigated for use/treatment in colorectal cancer and lung cancer.
N1,N11-Diethylnorspermine	Investigated for use/treatment in renal cell carcinoma, pancreatic cancer, melanoma, and lung cancer.
Squalamine	Investigated for use/treatment in ovarian cancer, lung cancer, and macular degeneration.
Porfiromycin	Investigated for use/treatment in head and neck cancer.
MLN576	Investigated for use/treatment in solid tumors.
Methyltestosterone	A synthetic anabolic steroid used for the replacement therapy in conditions associated with testosterone deficiencies in males, such as hypogonadism, and treatment of advancing inoperable metastatic breast cancer in females.
Ginsenoside C	Not Available
Besifloxacin	A fluoroquinolone antibiotic agent used for the treatment of bacterial conjunctivitis.
Hydroxyprogesterone caproate	A synthetic progestin used for the prevention of spontaneous preterm births in singleton pregnancies in women who have previously had a spontaneous preterm birth.
Lanreotide	A somatostatin analog used for the treatment of unresectable, well- or moderately-differentiated, locally advanced or metastatic gastroenteropancreatic neuroendocrine tumors and acromegaly.
Phenylbutyric acid	An agent indicated for the adjunctive therapy for the management of chronic urea cycle disorders due to deficiencies in specific enzymes, including the neonatal-onset deficiency and late-onset disease with a history of hyperammonemic encephalopathy.
Veliparib	Not Available
Hexestrol	A synthetic estrogen that has been used as a hormonal antineoplastic agent.
Nocodazole	Nocodazole is an antineoplastic agent which exerts its effect by depolymerizing microtubules.
Puromycin	Puromycin is an antibiotic that prevents bacterial protein translation. It is utilized as a selective agent in laboratory cell cultures. Puromycin is toxic to both prokaryotic and eukaryotic cells, resulting...
Formestane	For the treatment of estrogen-receptor positive breast cancer in post-menopausal women.
Radium Ra 223 dichloride	A radiopharmaceutical agent used to treat patients with castration-resistant prostate cancer, symptomatic bone metastases and no known visceral metastatic disease.
Flumequine	Flumequine is a synthetic chemotherapeutic antibiotic of the fluoroquinolone drug class used to treat bacterial infections.
Siltuximab	An interleukin antagonist used to treat multicentric Castleman's disease (MCD) in patients who are HIV and HHV-8 negative.
Podophyllin	A cytotoxic agent used for the removal of soft genital (venereal) warts (condylomata acuminata).
Dienogest	An oral progestin used for the treatment of endometriosis as monotherapy or contraception in combination with ethinylestradiol.
Niguldipine	Niguldipine is a calcium channel blocker drug (CCB) with a1-adrenergic antagonist properties.
Roquinimex	Roquinimex is investigated to be used as a treatment of a number of cancers and autoimmune conditions. As well, roquinimex is researched to be used as adjuvant therapy after bone...
Rabusertib	Rabusertib has been used in trials studying the treatment of Cancer, Solid Tumors, Advanced Cancer, Pancreatic Neoplasms, and Non Small Cell Lung Cancer.
Curcumin	No approved therapeutic indications.
SarCNU	2-chloroethyl-3-sarcosinamide-1-nitrosourea has been used in trials studying the treatment of Colorectal Cancer, Brain and Central Nervous System Tumors, and Unspecified Adult Solid Tumor, Protocol Specific.
Misonidazole	Misonidazole is under investigation in clinical trial NCT00038038 (Assessment of Head and Neck Tumor Hypoxia Using 18F-Fluoromisonidazole).
Bryostatin 1	Bryostatin 1 has been investigated for the treatment of HIV Infection and Alzheimer's Disease.
Talazoparib	A poly-ADP ribose polymerase inhibitor used to treat HER2-, BRCA mutated locally advanced or metastatic breast cancer.
Tremelimumab	An anti-CTLA-4 antibody used to treat unresectable hepatocellular carcinoma in combination with durvalumab.
Niraparib	A poly-ADP ribose polymerase inhibitor used to treat recurrent epithelial ovarian, fallopian tube, or primary peritoneal cancer responding to platinum based chemotherapy.
Saracatinib	Saracatinib has been investigated for the treatment of Cancer, Osteosarcoma, Ovarian Cancer, Fallopian Tube Cancer, and Primary Peritoneal Cancer.
Talaporfin	Talaporfin has been investigated for the treatment of Port-Wine Stain and Benign Prostatic Hyperplasia.
Crenolanib	Crenolanib is under investigation for the treatment of Diffuse Intrinsic Pontine Glioma and Progressive or Refractory High-Grade Glioma.
Entinostat	Entinostat is under investigation for the treatment and other of Volunteers, Breast Cancer, Human Volunteers, and Normal Volunteers. Entinostat has been investigated for the treatment of Non-Small Lung Cancer, Epigenetic...
Acridine Carboxamide	Acridine Carboxamide has been used in trials studying the treatment of Lung Cancer and Brain and Central Nervous System Tumors.
Infigratinib	An FGFR inhibitor used to treat locally advanced or metastatic cholangiocarcinoma in adults with a fibroblast growth factor receptor 2 (FGFR2) rearrangement.
Efatutazone	Efatutazone has been used in trials studying the treatment of Lymphoma, Liposarcoma, Solid Tumors, Multiple Myeloma, and Recurrent Thyroid Cancer, among others.
6-O-benzylguanine	6-O-benzylguanine has been used in trials studying the treatment of HIV Infection, Adult Gliosarcoma, Adult Glioblastoma, Stage I Adult Hodgkin Lymphoma, and Stage II Adult Hodgkin Lymphoma, among others.
Carboxyamidotriazole	Carboxyamidotriazole has been used in trials studying the treatment of Lymphoma, Lung Cancer, Breast Cancer, Kidney Cancer, and Ovarian Cancer, among others.
Triptolide	Triptolide has been used in trials studying the treatment of HIV, Crohn's Disease, Intestinal Diseases, Gastrointestinal Diseases, and Digestive System Diseases, among others.
Broxuridine	Broxuridine has been used in trials studying the treatment of Leukemia, Stage I Prostate Cancer, Stage IIB Prostate Cancer, and Stage IIA Prostate Cancer.
Trebananib	Trebananib is under investigation for the treatment of Ovarian Cancer, Peritoneal Cancer, and Fallopian Tube Cancer. Trebananib has been investigated for the treatment of Cancer, Oncology, Carcinoma, Metastases, and Colon...
Anecortave	Anecortave is under investigation in clinical trial NCT00691717 (Anecortave Acetate Safety in Patients With Open-Angle Glaucoma or Ocular Hypertension).
Vesnarinone	Vesnarinone has been used in trials studying the treatment of HIV Infections and Sarcoma, Kaposi.
Mafosfamide	Mafosfamide has been used in trials studying the treatment of Lymphoma, Leukemia, Meningeal Neoplasm, and Brain and Central Nervous System Tumors.
LCL-161	LCL161 has been used in trials studying the treatment of Leukemia, Neoplasms, Solid Tumors, Breast Cancer, and Ovarian Cancer, among others.
Taselisib	Taselisib has been used in trials studying the treatment and basic science of LYMPHOMA, Breast Cancer, Ovarian Cancer, Solid Neoplasm, and HER2/Neu Negative, among others.
Epigallocatechin gallate	Epigallocatechin gallate has been investigated for the treatment of Hypertension and Diabetic Nephropathy.
Namitecan	Namitecan has been used in trials studying the treatment of Solid Tumors.
Duligotuzumab	Duligotuzumab has been used in trials studying the treatment of Neoplasms, Colorectal Cancer, Head and Neck Cancer, and Epithelial Tumors, Malignant.
Cordycepin	Cordycepin has been used in trials studying the treatment of Leukemia.
Binetrakin	Binetrakin has been used in trials studying the treatment of HIV Infections, Sarcoma, Kaposi, Non-Hodgkin's Lymphoma (NHL), Myelodysplastic Syndrome (MDS), and Leukemia, Acute Myelogenous (AML), among others.
Exatecan	Exatecan has been used in trials studying the treatment of Sarcoma, Leukemia, Lymphoma, Lung Cancer, and Liver Cancer, among others.
Lurtotecan	Lurtotecan is under investigation in clinical trial NCT00022594 (Liposomal Lurtotecan in Treating Patients With Metastatic or Locally Recurrent Head and Neck Cancer).
KRN-7000	KRN7000 has been used in trials studying the treatment of Lung Cancer, Chronic Hepatitis C, Hepatitis B, Chronic, Unspecified Adult Solid Tumor, Protocol Specific, and Prevention of GvHD in Patients...
Epofolate	Epofolate has been used in trials studying the treatment of Advanced Solid Tumors. Epofolate (BMS-753493) is a folate conjugate of the epothilone analog BMS-748285 that was designed to selectively target...
OBP-801	OBP-801 has been used in trials studying the treatment of Solid Tumor.
Rucaparib	A poly (ADP-ribose) polymerase (PARP) inhibitor used to treat recurrent ovarian and prostate cancers in previously treated adults.
Navitoclax	Navitoclax has been used in trials studying the treatment and basic science of Solid Tumors, Non-Hodgkin's Lymphoma, EGFR Activating Mutation, Chronic Lymphoid Leukemia, and Hematological Malignancies, among others. Navitoclax is...
Bizelesin	Bizelesin has been used in trials studying the treatment of Unspecified Adult Solid Tumor, Protocol Specific.
Indirubin	Indirubin is under investigation in clinical trial NCT01735864 (Dosage Determination Trial for Indigo Naturalis Extract in Oil Ointment).
Merestinib	Merestinib has been used in trials studying the treatment of Cancer, Solid Tumor, Advanced cancer, ColoRectal Cancer, and Metastatic Cancer, among others.
10-hydroxycamptothecin	10-hydroxycamptothecin is under investigation in clinical trial NCT00956787 (Study of AR-67 (DB-67) in Myelodysplastic Syndrome (MDS)).
Sulforaphane	Sulforaphane is under investigation for the treatment of Autism Spectrum Disorder. It is a naturally occurring isothiocyanate found in high concentration in a variety of broccoli.
Belotecan	Belotecan has been investigated for the treatment of Epithelial Ovarian Cancer.
Taurolidine	An antimicrobial derivative of taurine used for prophylaxis of catheter-related infections.
9-aminocamptothecin	Aminocamptothecin has been used in trials studying the treatment of Lymphoma, Gastric Cancer, Ovarian Cancer, Esophageal Cancer, and Ovarian Neoplasms, among others.
Molgramostim	Molgramostim has been used in trials studying the treatment of Bronchiectasis, Cystic Fibrosis, Pulmonary Alveolar Proteinosis, Acute Respiratory Distress Syndrome, and Autoimmune Pulmonary Alveolar Proteinosis.
Oltipraz	Oltipraz has been used in trials studying the treatment and prevention of Lung Cancer, Liver Fibrosis, Liver Cirrhosis, and Non-alcoholic Fatty Liver Disease.
Pyrazoloacridine	Pyrazoloacridine has been used in trials studying the treatment of Lung Cancer, Liver Cancer, Breast Cancer, Melanoma (Skin), and Metastatic Cancer, among others.
Fosbretabulin	Fosbretabulin has been investigated for the treatment of Anaplastic Thyroid Cancer.
Apaziquone	Apaziquone has been investigated for the treatment of Bladder Cancer and Bladder Neoplasms.
Combretastatin	Combretastatin has been investigated for the treatment of Anaplastic Thyroid Cancer.
Mizoribine	Mizoribine has been investigated for the treatment of Rheumatoid Arthritis.
Onapristone	Onapristone has been used in trials studying the treatment of Prostate Cancer, Recurrent Prostate Cancer, Metastatic Prostate Cancer, Androgen-independent Prostate Cancer, and Progesterone Receptor Positive Tumor: Max 1 Line of...
Soblidotin	Soblidotin has been used in trials studying the treatment of Sarcoma, Lung Cancer, and Unspecified Adult Solid Tumor, Protocol Specific.
Salirasib	Salirasib has been used in trials studying the diagnostic of Carcinoma, Non-Small-Cell Lung.
Gusperimus	Gusperimus has been used in trials studying the treatment of Lupus Nephritis, Wegeners Granulomatosis, and Wegener's Granulomatosis.
Phenethyl Isothiocyanate	Phenethyl Isothiocyanate has been used in trials studying the prevention and treatment of Leukemia, Lung Cancer, Tobacco Use Disorder, and Lymphoproliferative Disorders.
Methylselenocysteine	Methylselenocysteine has been used in trials studying the prevention of Prostate Carcinoma and No Evidence of Disease.
Dolastatin 10	Dolastatin 10 has been used in trials studying the treatment of Sarcoma, Leukemia, Lymphoma, Liver Cancer, and Kidney Cancer, among others.
Etanidazole	Etanidazole has been used in trials studying the diagnostic of Adult Ependymoma, Malignant Ascites, Adult Gliosarcoma, Adult Mixed Glioma, and Adult Glioblastoma, among others.
Lometrexol	Lometrexol has been used in trials studying the treatment of Lung Cancer, Drug/Agent Toxicity by Tissue/Organ, and Unspecified Adult Solid Tumor, Protocol Specific.
Buthionine sulfoximine	Buthionine sulfoximine has been used in trials studying the treatment of Neuroblastoma and Melanoma (Skin).
Dianhydrogalactitol	Dianhydrogalactitol has been used in trials studying the treatment of GBM, Glioma, Glioblastoma, Brain Cancer, and Glioblastoma Multiforme.
Indole-3-carbinol	Indole 3 Carbinol is under investigation in clinical trial NCT00033345 (Indole-3-Carbinol in Preventing Breast Cancer in Nonsmoking Women Who Are at High Risk For Breast Cancer).
Fiacitabine	Fiacitabine has been used in trials studying the treatment of HIV Infections and Cytomegalovirus Infections.
Nolatrexed	Nolatrexed is under investigation in clinical trial NCT00012324 (Nolatrexed Dihydrochloride Compared With Doxorubicin in Treating Patients With Recurrent or Unresectable Liver Cancer).
Mitolactol	Mitolactol has been used in trials studying the treatment of Brain and Central Nervous System Tumors.
Pinometostat	Pinometostat has been used in trials studying the treatment of Leukemia, Acute Leukemias, Acute Myeloid Leukemia, Myelodysplastic Syndrome, and Acute Lymphocytic Leukemia, among others.
Doxifluridine	Doxifluridine has been investigated for the treatment of Stomach Cancer.
Didox	Didox has been used in trials studying the supportive care of Gastric Cancer.
Penclomedine	Penclomedine has been used in trials studying the treatment of Lymphoma and Unspecified Adult Solid Tumor, Protocol Specific.
Deoxyspergualin	Deoxyspergualin has been used in trials studying the treatment of Lupus Nephritis, Chronic Rejection, and Diabetes Mellitus, Type 1.
Acteoside	Acteoside is under investigation in clinical trial NCT02662283 (Validity and Security of Reh-acteoside Therapy for Patients of IgA Nephropathy).
Hypericin	Hypericin is under investigation for the treatment of Cutaneous T-cell Lymphoma.
Liarozole	Liarozole has been used in trials studying the treatment of Ichthyosis, Lamellar.
Sizofiran	A beta-D-glucan obtained from the Aphyllophoral fungus Schizophyllum commune. It is used as an immunoadjuvant in the treatment of neoplasms, especially tumors found in the stomach. Sizofiran has been used...
Nedaplatin	Used in the treatment of non-small cell lung cancer, small cell lung cancer, oesophygeal cancer, and head and neck cancers .
Daidzein	Not Annotated
Lentinan	Not Annotated
Oxolinic acid	Not Annotated
Vorozole	Not Annotated
Iniparib	Not Annotated
Coumermycin A1	Not Annotated
Toyocamycin	4-Amino-5-cyano-7-(D-ribofuranosyl)-7H- pyrrolo(2,3-d)pyrimidine. Antibiotic antimetabolite isolated from Streptomyces toyocaensis cultures. It is an analog of adenosine, blocks RNA synthesis and ribosome function, and is used mainly as a tool in biochemistry.
Tretamine	Toxic alkylating agent used in industry; also as antineoplastic and research tool to produce chromosome aberrations and cancers.
Masoprocol	Used for the treatment of actinic keratoses (precancerous skin growths that can become malignant if left untreated).
Anagrelide	A platelet-reducing agent used to treat thrombocythemia, and its related complications, secondary to myeloproliferative neoplasms.
Aminolevulinic acid	A porphyrin precursor used to treat actinic keratosis of the face, scalp, and upper extremities, as well as to visualize a glioma.
Methyl aminolevulinate	A porphyrin precursor used to treat non-hyperkeratotic, non-pigmented actinic keratosis of the face and scalp.
Ixabepilone	A microtubule inhibitor administered in combination with capecitabine or alone in the treatment of metastatic or locally advanced breast cancer that has shown inadequate response to taxanes and anthracyclines.
Sitimagene ceradenovec	Intended for the treatment of brain cancer.
Vintafolide	Investigated for use/treatment in solid tumors.
Ridaforolimus	Investigated for use/treatment in solid tumors, sarcoma, cancer/tumors (unspecified), endometrial cancer, prostate cancer, and bone metastases.
Pralatrexate	An antineoplastic agent used for the treatment of relapsed or refractory peripheral T-cell lymphoma.
Efaproxiral	Not Available
Cabozantinib	A tyrosine kinase inhibitor used to treat advanced renal cell carcinoma, hepatocellular carcinoma, and medullary thyroid cancer.
Dinutuximab	An immunotherapeutic agent used in combination with other immunomodulating agents to treat high-risk neuroblastoma in pediatric patients who achieve at least a partial response to prior first-line multiagent, multimodality therapy.
Sonidegib	An antineoplastic agent used for the treatment of locally advanced recurrent basal cell carcinoma (BCC) following surgery and radiation therapy, or in cases where surgery or radiation therapy are not appropriate.
Masitinib	Masitinib is a tyrosine-kinase inhibitor used in the treatment of mast cell tumors in dogs. It has been available in Europe since 2009, under the brand name Masivet. In the...
Vinflunine	A vinca alkaloid used to treat advanced or metastatic transitional cell carcinoma of the urothelial tract after a platinum containing treatment has failed.
Tivozanib	A kinase inhibitor to treat adult patients with renal cell carcinoma (RCC) who have failed prior systemic therapies or experienced relapsed disease.
Mannosulfan	Not Annotated
Edrecolomab	Not Annotated
Paclitaxel poliglumex	Not Annotated
Oblimersen	Not Annotated
Interferon alfa-2b	A form of recombinant human interferon used to treat hepatitis B and C infection, genital warts, hairy cell leukemia, follicular lymphoma, malignant melanoma, and AIDs-related Kaposi's sarcoma.
Cobimetinib	An antineoplastic agent and selective inhibitor of the mitogen-activated extracellular kinase (MEK) pathway used to treat unresectable or metastatic melanoma.
Inotuzumab ozogamicin	An antibody-drug conjugate used to treat B-cell precursor acute lymphoblastic leukemia (ALL).
Olaratumab	A platelet-derived growth factor receptor alpha blocking antibody used with doxorubicin to treat patients with certain types of soft tissue sarcoma (STS).
Elotuzumab	An antineoplastic agent and SLAMF7-directed immunostimulatory antibody used for the treatment of refractory multiple myeloma in combination with other antineoplastic agents.
Degarelix	A GnRH receptor antagonist used in the management of advanced prostate cancer.
Buserelin	A LHRH agonist used for the palliative treatment of hormone-dependent advanced carcinoma of the prostate gland in males and treatment of endometriosis in females.
Asparaginase Erwinia chrysanthemi	An asparagine-specific enzyme used as part of a chemotherapeutic regimen to treat patients with acute lymphoblastic leukemia and lymphoblastic lymphoma.
Enzalutamide	A second-generation androgen receptor inhibitor used to treat castration-resistant prostate cancer and metastatic castration-sensitive prostate cancer.
Alectinib	A kinase inhibitor used to treat anaplastic lymphoma kinase positive metastatic non small cell lung cancer.
Venetoclax	A BCL-2 inhibitor used to treat chronic lymphocytic leukemia, small lymphocytic lymphoma, or acute myeloid leukemia.
Atezolizumab	A monoclonal antibody used to treat advanced or metastatic urothelial carcinoma with disease progression during or up to 12 months after platinum-containing chemotherapy.
Durvalumab	An antineoplastic monoclonal antibody used to treat urothelial carcinoma and locally advanced, unresectable non-small cell lung cancer.
Ribociclib	A kinase inhibitor used to treat HR+, HER2- advanced or metastatic breast cancer.
Avelumab	A monoclonal antibody used to treat metastatic merkel cell carcinoma, metastatic urothelial carcinoma, or renal cell carcinoma.
Genistein	Currently Genistein is being studied in clinical trials as a treatment for prostate cancer.
Trifluridine	A nucleoside metabolic inhibitor used to treat keratoconjunctivitis and epithelial keratitis caused by simplex virus, and as a part of chemotherapy for certain types of metastatic gastrointestinal cancers.
Vincamine	Vincamine is a monoterpenoid indole alkaloid obtained from the leaves of Vinca minor with a vasodilatory property. Studies indicate that vincamine increases the regional cerebral blood flow.
Pracinostat	For the treatment of various forms of cancer.
Mocetinostat	Mocetinostat has been used in trials studying the treatment of Lymphoma, Urothelial Carcinoma, Relapsed and Refractory, Myelodysplastic Syndrome, and Metastatic Leiomyosarcoma, among others.
Fimepinostat	Fimepinostat (CUDC-907) has been used in trials studying the treatment of lymphoma, solid tumors, breast cancer, multiple myeloma, and NUT midline carcinoma, among others.
CG-200745	Cg200745 has been used in trials studying the treatment of Solid Tumour.
Ricolinostat	Ricolinostat is under investigation for the treatment of Breast Carcinoma and Metastatic Breast Cancer.
R-306465	R306465 has been used in trials studying the treatment of Neoplasms.
Abexinostat	Abexinostat has been used in trials studying the treatment of Sarcoma, Lymphoma, Leukemia, Lymphocytic, and Hodgkin Disease, among others. It is a novel, broad-spectrum hydroxamic acid-based inhibitor of histone deacetylase...
Givinostat	Givinostat has been used in trials studying the treatment of Polycythemia Vera, Juvenile Idiopathic Arthritis, Duchenne Muscular Dystrophy (DMD), Chronic Myeloproliferative Neoplasms, and Polyarticular Course Juvenile Idiopathic Arthritis.
Valproic acid	An anticonvulsant used to control complex partial seizures and both simple and complex absence seizures.
Bufexamac	An NSAID used to treat skin conditions like atopic eczema and inflammatory dermatoses.
Tetrandrine	Not Annotated
Dofequidar	Dofequidar is an antineoplastic agent.
Dexniguldipine	Not Annotated
Paclitaxel trevatide	Investigated for use/treatment in brain cancer.
Aldoxorubicin	Investigated for use/treatment in solid tumors.
Peginterferon alfa-2a	A modified form of recombinant human interferon used to stimulate the innate antiviral response in the treatment of hepatitis B and C viruses.
Tucidinostat	Investigated for use/treatment in cancer/tumors (unspecified).
CUDC-101	CUDC-101 has been used in trials studying the treatment of Cancer, Tumors, Liver Cancer, Breast Cancer, and Gastric Cancer, among others.
Methylprednisolone hemisuccinate	A water soluble corticosteroid used to treat severe allergic reactions, dermatologic diseases, endocrine disorders, gastrointestinal diseases, hematological disorders, neoplastic diseases, nervous system conditions, ophthalmic diseases, renal diseases, respiratory diseases, and rheumatic disorders.
Prednisone acetate	Not Annotated
Combretastatin A4	Not Annotated
Moxetumomab pasudotox	A CD22-specific antibody conjugated to a truncated exotoxin used to treat relapsed or refractory hairy cell leukemia in patients who have already been treated with a purine nucleoside analog and one other treatment.
Platinum	Platinum is under investigation for the treatment of Metastatic Breast Cancer, Non-small Cell Lung Cancer, Gastric Large Cell Neuroendocrine Carcinoma, Colorectal Large Cell Neuroendocrine Carcinoma, and Pancreatic Large Cell Neuroendocrine...
Dacomitinib	A medication used to treat non small cell lung cancer with EGFR exon 19 deletion of exon 21 L858R substitution.
Brequinar	Not Available
Piritrexim	Piritrexim has been used in trials studying the treatment of Bladder Cancer, Urethral Cancer, and Transitional Cell Cancer of the Renal Pelvis and Ureter.
7-ethyl-10-hydroxycamptothecin	Investigated for use/treatment in colorectal cancer.
TNP-470	O-(chloroacetylcarbamoyl)fumagillol (TNP-470) has been used in trials studying the treatment of HIV Infections, Sarcoma, Kaposi, and Pancreatic Neoplasms.
Betulinic Acid	Betulinic Acid has been used in trials studying the treatment of Dysplastic Nevus Syndrome.
Gilteritinib	An AXL receptor tyrosine kinase inhibitor used to treat relapsed or refractory acute myeloid leukemia.
IMO-2055	Investigated for use/treatment in renal cell carcinoma, solid tumors, and lung cancer.
Tagraxofusp	A CD123-directed cytotoxin used to treat blastic plasmacytoid dendritic cell neoplasm.
Vadimezan	Investigated for use/treatment in solid tumors, lung cancer, ovarian cancer, and prostate cancer.
Glasdegib	A sonic hedgehog receptor inhibitor used to treat newly diagnosed acute myeloid leukemia in patients over 75 years who cannot receive intense chemotherapy.
Plitidepsin	Intended for the treatment of various forms of cancer.
Epacadostat	Epacadostat has been used in trials studying the treatment of HL, Melanoma, Glioblastoma, Mucosal Melanoma, and Ovarian Carcinoma, among others.
Encorafenib	A kinase inhibitor used to treat unresectable or metastatic melanoma with specific mutations.
Icotinib	Icotinib hydrochloride is a novel epidermal growth factor receptor (EGFR)–tyrosine kinase inhibitor, exhibits encouraging efficacy and tolerability in patients with advanced non-small-cell lung cancer (NSCLC) who failed previous chemotherapy.
Neratinib	A protein kinase inhibitor used to treat breast cancer that over expresses the HER2 receptor.
Rociletinib	Rociletinib has been used in trials studying the treatment and prevention of Nonsmall Cell Lung Cancer, Non-small Cell Lung Cancer, and Locally Advanced or Metastatic Non-small Cell Lung Cancer.
Binimetinib	A medication used to treat metastatic melanoma with specific mutations.
Vosaroxin	Vosaroxin is under investigation for the treatment of Leukemia, Myeloid, Acute.
Abemaciclib	A medication used to treat HR+ HER2- advanced or metastatic breast cancer.
Lorlatinib	An anaplastic lymphoma kinase inhibitor used to treat anaplastic lymphoma kinase positive metastatic non small cell lung cancer.
Brigatinib	An anaplastic lymphoma kinase inhibitor used to treat anaplastic lymphoma kinase positive metastatic non small cell lung cancer.
Copanlisib	A medication used to treat relapsed follicular lymphoma who have attempted at least two other treatments.
Mogamulizumab	A monoclonal antibody used to treat relapsed or refractory mycosis fungoides or Sézary syndrome after attempting one other therapy.
Olmutinib	For use in treatment of metastatic T790M mutation positive non-small cell lung cancer .
Enasidenib	An isocitrate dehydrogenase-2 inhibitor used to treat relapsed or refractory acute myeloid leukemia with an isocitrate dehydrogenase-2 mutation.
Talimogene laherparepvec	A genetically modified virus used to treat recurrent melanoma, or metastatic melanoma.
Erdafitinib	A fibroblast growth factor receptor tyrosine kinase inhibitor used to treat locally advanced or metastatic urothelial carcinoma.
Dordaviprone	Dordaviprone (ONC-201) is under investigation in clinical trial NCT03394027 (ONC201 in Recurrent/Refractory Metastatic Breast Cancer and Advanced Endometrial Carcinoma).
Human interleukin-2	Human interleukin-2 is under investigation in clinical trial NCT03475134 (TIL-ACT After NMA Chemo With IL-2 and Nivo Rescue in mMEL).
Etirinotecan pegol	Etirinotecan pegol is under investigation in clinical trial NCT01663012 (Phase II NKTR-102 In Bevacizumab-Resistant High Grade Glioma).
NUC-1031	NUC-1031 is under investigation in clinical trial NCT03610100 (Acelarin First Line Randomised Pancreatic Study).
Perillyl alcohol	Perillyl alcohol is under investigation in clinical trial NCT02704858 (Safety and Efficacy Study in Recurrent Grade IV Glioma).
Biochanin A	Biochanin A is under investigation in clinical trial NCT02174666 (Isoflavone Treatment for Postmenopausal Osteopenia.).
Dihematoporphyrin ether	Dihematoporphyrin ether is under investigation in clinical trial NCT00118222 (High Light and Low Light Dose PDT in Glioma).
Pidilizumab	Pidilizumab is under investigation in clinical trial NCT01952769 (Anti PD1 Antibody in Diffuse Intrinsic Pontine Glioma).
Bermekimab	Bermekimab is under investigation in clinical trial NCT01384630 (Safety, Pharmacokinetics, and Efficacy of RA-18C3 in Subjects With Moderate to Severe Psoriasis).
Tefinostat	Tefinostat is under investigation in clinical trial NCT02759601 (Dose Escalation Trial of Tefinostat for Cancer Associated Inflamation in Hepatocellular Carcinoma (HCC)).
Nanatinostat	Nanatinostat is under investigation in clinical trial NCT00697879 (Safety Study of the Histone Deacetylase Inhibitor, CHR-3996, in Patients With Advanced Solid Tumours).
Apalutamide	An androgen receptor inhibitor used to treat non metastatic, castration resistant prostate cancer.
Alpelisib	Alpelisib is indicated in combination with fulvestrant to treat postmenopausal women, and men, with advanced or metastatic breast cancer. This cancer must be hormone receptor (HR)-positive, human epidermal growth factor...
Tubercidin	An antibiotic purine ribonucleoside that readily substitutes for adenosine in the biological system, but its incorporation into DNA and RNA has an inhibitory effect on the metabolism of these nucleic...
Trimetrexate	A folate antagonist used for the treatment of moderate-to-severe Pneumocystis carinii pneumonia (PCP) in immunocompromised patients as an alternative therapy in combination with leucovorin.
Epothilone D	Investigated for use/treatment in colorectal cancer, lung cancer, breast cancer, solid tumors, and prostate cancer.
Monastrol	Not Available
Galiximab	Investigated for use/treatment in lymphoma (non-hodgkin's), psoriasis and psoriatic disorders, bone metastases, multiple myeloma, prostate cancer, and rheumatoid arthritis.
Epratuzumab	Investigated for use/treatment in leukemia (lymphoid), lymphoma (non-hodgkin's), and systemic lupus erythematosus.
Oregovomab	Investigated for use/treatment in ovarian cancer.
Banoxantrone	For the treatment of various forms of cancer.
Labetuzumab	Labetuzumab is a humanized monoclonal antibody used to treat cancer. Retrieved from "http://en.wikipedia.org/wiki/Labetuzumab"
Bavituximab	Investigated for use/treatment in breast cancer, cancer/tumors (unspecified), HIV infection, hepatitis (viral, C), and solid tumors.
Rindopepimut	Investigated for use/treatment in brain cancer.
Pelitinib	Investigated for use/treatment in colorectal cancer and lung cancer.
Farletuzumab	Investigated for use/treatment in ovarian cancer.
Veltuzumab	Investigated for use/treatment in lymphoma (non-hodgkin's).
CT-011	Investigated for use/treatment in cancer/tumors (unspecified).
Glembatumumab vedotin	Investigated for use/treatment in melanoma.
AV-412	Investigated for use/treatment in cancer/tumors (unspecified).
Filanesib	Investigated for use/treatment in cancer/tumors (unspecified).
Nimotuzumab	An EGFR-targeting monoclonal antibody used in the treatment of squamous cell carcinomas of the head and neck and glioblastomas.
Atrasentan	Investigated for use/treatment in prostate cancer and cancer/tumors (unspecified).
Sapacitabine	Investigated for use/treatment in solid tumors, cutaneous t-cell lymphoma, myelodysplastic syndrome, and leukemia (lymphoid).
Indisulam	Investigated for use/treatment in lung cancer.
Volociximab	Investigated for use/treatment in solid tumors, renal cell carcinoma, melanoma, pancreatic cancer, lung cancer, and ovarian cancer.
Finafloxacin	Finafloxacin is indicated for the treatment of acute otitis externa (AOE) with or without an otowick, caused by susceptible strains of Pseudomonas aeruginosa and Staphylococcus aureus in patients age 1...
Artesunate	Artesunate is an artemesinin derivative indicated for the initial treatment of severe malaria.
Silibinin	A flavonolignan with hepatoprotective effects used to treat toxic liver damage and as an adjunct in the management of chronic conditions such as cirrhosis and hepatitis.
Conatumumab	Conatumumab has been used in trials studying the treatment of Sarcoma, Lymphoma, Oncology, Colon Cancer, and Rectal Cancer, among others.
Dactolisib	Dactolisib has been used in trials studying the treatment of Cancer, Solid Tumor, Renal Cancer, Breast Cancer, and Cowden Syndrome, among others.
Ortataxel	Ortataxel has been used in trials studying the treatment of Lymphoma, Lung Cancer, Glioblastoma, and Kidney Cancer.
Ilorasertib	Ilorasertib has been used in trials studying the treatment of Myelodysplasia, Solid Neoplasm, Advanced Cancers, Advanced Solid Tumors, and Acute Myelogenous Leukemia, among others.
Endostar	Endostar is under investigation for the treatment of Nasopharyngeal Carcinoma. Endostar has been investigated for the treatment of Non-small Cell Lung Cancer.
GSK-2636771	GSK2636771 has been used in trials studying the treatment of CANCER, LYMPHOMA, Solid Neoplasm, Recurrent Solid Neoplasm, and Advanced Malignant Neoplasm, among others.
Guadecitabine	Guadecitabine is under investigation for the treatment of Previously Treated Metastatic Colorectal Cancer.
Rilotumumab	Rilotumumab has been investigated for the treatment of Cancer, Lung Cancer, Solid Tumors, Gastric Cancer, and Prostate Cancer, among others.
Tesevatinib	Tesevatinib has been used in trials studying the treatment of Cancer, Stomach Cancer, Brain Metastases, Esophageal Cancer, and Leptomeningeal Metastases, among others. Tesevatinib is a potent inhibitor of multiple RTKs...
Naquotinib	Naquotinib has been used in trials studying the treatment of Solid Tumors, Non-small Cell Lung Cancer, Non-Small-Cell Lung Cancer (NSCLC), Epidermal Growth Factor Receptor Mutations, and Epidermal Growth Factor Receptor...
Lorvotuzumab mertansine	Lorvotuzumab mertansine has been used in trials studying the treatment of SCLC, Leukemia, Ovarian Cancer, Multiple Myeloma, and Merkel Cell Carcinoma, among others.
Rigosertib	Rigosertib has been used in trials studying the treatment and basic science of MDS, RAEB, Cancer, Hepatoma, and Neoplasms, among others.
Zalutumumab	Zalutumumab is a fully human IgG1 monoclonal antibody designed to bind with selectivity to the epidermal growth factor receptor (EGFR). Zalutumumab has been investigated for the treatment of Squamous Cell...
Sagopilone	Sagopilone has been used in trials studying the treatment of Melanoma, Neoplasms, CNS Disease, Breast Cancer, and Breast Neoplasms, among others. It is a so-called fully synthetic epothilone and is...
Dacetuzumab	Investigated for use/treatment in lymphoma (non-hodgkin's) and multiple myeloma.
Zelavespib	Zelavespib (PU-H71) has been used in trials studying the treatment of LYMPHOMA, Solid Tumors, Metastatic Solid Tumor, and Myeloproliferative Neoplasms (MPN).
Beloranib	Beloranib has been used in trials studying the treatment of Obesity, Over-weight, Type 2 Diabetes, Craniopharyngioma, and Hypothalamic Injury, among others.
Intetumumab	Intetumumab has been used in trials studying the treatment of Melanoma.
Ecromeximab	Ecromeximab has been used in trials studying the treatment of Cutaneous Melanoma and Metastatic Melanoma.
Rebastinib	Rebastinib has been used in trials studying the treatment of Chronic Myeloid Leukemia. It is an inhibitor of Tie2 tyrosine kinase receptor and an antineoplastic agent.
Tocladesine	Tocladesine has been used in trials studying the treatment of Colorectal Cancer and Multiple Myeloma and Plasma Cell Neoplasm.
X-396	X-396 has been used in trials studying the treatment of Advanced Solid Tumors and Non-small Cell Lung Cancer.
Ivosidenib	An isocitrate dehydrogenase-1 inhibitor used to treat acute myeloid leukemia and cholangiocarcinoma in adults with a susceptible IDH1 mutation.
Cemiplimab	A programmed death receptor-1 blocking antibody used to treat cutaneous squamous cell carcinoma, basal cell carcinoma, and non-small cell lung cancer.
Rivoceranib	Rivoceranib is under investigation in clinical trial NCT02726854 (Apatinib as Second-line Treatment of Advanced Pancreatic Cancer).
AZD-5991	AZD-5991 is under investigation in clinical trial NCT03218683 (Study of AZD5991 in Relapsed or Refractory Haematologic Malignancies.).
Ensartinib	Ensartinib is under investigation in clinical trial NCT03420508 (Treating Patients With Melanoma and ALK Alterations With Ensartinib).
Lintuzumab	Lintuzumab is under investigation in clinical trial NCT00016159 (Chemotherapy Plus Monoclonal Antibody in Treating Patients With Acute Promyelocytic Leukemia).
Zanubrutinib	A kinase inhibitor used to treat mantle cell lymphoma, a type of B-cell non-Hodgkin lymphoma, in adults who previously received therapy.
Voruciclib	Voruciclib is under investigation in clinical trial NCT03547115 (A Phase 1 Study of Voruciclib in Subjects With B-Cell Malignancies or AML).
KRN-5500	KRN-5500 is under investigation in clinical trial NCT00002923 (KRN5500 in Treating Patients With Metastatic Solid Tumors).
SOR-C13	SOR-C13 is under investigation in clinical trial NCT01578564 (Safety and Tolerability Study of SOR-C13 in Subjects With Advanced Cancers Commonly Known to Express the TRPV6 Channel).
Tallimustine	An alkylating agent previously investigated for it's antitumor activity but was stopped due to severe myelotoxicity.
Pexidartinib	An antitumor agent that is used for the treatment of rare disease tenosynovial giant cell tumors (TGCT) by inhibiting colony-stimulating factor 1 and its receptor.
Cinnamaldehyde	Cinnamaldehyde is approved by the FDA for use within allergenic epicutaneous patch tests which are indicated for use as an aid in the diagnosis of allergic contact dermatitis (ACD) in...
Entrectinib	Entrectinib is indicated for the treatment of metastatic ROS1-positive non-small cell lung cancer in adults. Entrectinib is also indicated in adults and children over 12 years old for the treatment...
Larotrectinib	A kinase inhibitor used to treat solid tumors with neurotrophic receptor tyrosine kinase gene fusion, are metastatic, high risk for surgery, or have no alternative treatments.
Acalabrutinib	A Bruton tyrosine kinase inhibitor used to treat mantle cell lymphoma, chronic lymphocytic leukemia, and small lymphocytic lymphoma.
4-(dimethylamino)-N-[7-(hydroxyamino)-7-oxoheptyl]benzamide	Not Available
N-hydroxyguanidine	Not Available
Padeliporfin	A vascular-acting photosensitizer used to treat low-risk prostate cancer in adults.
Echinomycin	Echinomycin is a cytotoxic polypeptide quinoxaline antibiotic isolated from Streptomyces echinatus that binds to DNA and inhibits RNA synthesis.
Ursolic acid	Not Annotated
Volasertib	Volasertib has been used in trials studying the treatment of Leukemia, Neoplasms, Leukemia, Myeloid, Acute, Myelodysplastic Syndromes, and Leukemia, Monocytic, Acute, among others.
MIV-711	Not Annotated
Axicabtagene ciloleucel	A CAR T-cell therapy used to treat adults with large B-cell lymphomas and follicular lymphoma.
Bropirimine	Not Available
Lexacalcitol	Lexacalcitol is a solid. This compound belongs to the vitamin D and derivatives class of chemicals. These are compounds containing a secosteroid backbone, usually secoergostane or secocholestane. It is known...
Trichostatin A	Not Available
alpha,beta-Methyleneadenosine 5'-triphosphate	Not Available
5'-S-methyl-5'-thioadenosine	Not Available
Sodium phosphate P 32	Not Annotated
Edodekin alfa	Edodekin alfa is under investigation in clinical trial NCT01468896 (Cetuximab and Recombinant Interleukin-12 in Treating Patients With Squamous Cell Carcinoma of the Head and Neck That Is Recurrent, Metastatic, or...
AMG-337	AMG-337 is under investigation in clinical trial NCT03147976 (QUILT-3.036: AMG 337 in Subjects With Advanced or Metastatic Solid Tumors).
Isatuximab	A chimeric monoclonal antibody targeted against surface CD38 glycoproteins for the treatment of multiple myeloma in patients who have failed previous therapies.
Droloxifene	Droloxifene, a derivative of the triphenylethylene drug tamoxifen, is a novel selective estrogen receptor modulator (SERM). Droloxifene also exhibits more rapid pharmacokinetics, reaching peak concentrations and being eliminated much more...
Pemigatinib	A kinase inhibitor used to treat locally advanced or metastatic, unresectable cholangiocarcinoma in previously treated adult patients.
Darolutamide	An androgen receptor antagonist used for castration-resistant, non-metastatic prostate cancer and metastatic hormone-sensitive prostate cancer.
Capmatinib	A kinase inhibitor targeting c-Met receptor tyrosine kinase in the treatment of non-small cell lung cancer with MET exon 14 skipping.
Selpercatinib	A RET receptor tyrosine kinase inhibitor for the treatment of RET-driven non-small cell lung cancer, medullary thyroid cancer, and thyroid cancer in appropriate patient populations.
Incadronic acid	Incadronate has been investigated in the treatment of myeloma,[A14426,A14431] leukemia, and other cancers. It has also been investigated in patients with hypercalcemia of malignancy.
Talactoferrin alfa	Investigated for use/treatment in adverse effects (chemotherapy), cancer/tumors (unspecified), diabetic foot ulcers, lung cancer, solid tumors, and ulcers.
Brexucabtagene autoleucel	A modified autologous chimeric antigen receptor (CAR) T cell therapy employing a modified murine anti-CD19 single-chain variable fragment linked to CD28 and CD3ζ co-stimulatory domains for the treatment of patients with relapsed and refractory mantle cell lymphoma.
Selinexor	Selinexor is indicated in combination with bortezomib and dexamethasone for the treatment of multiple myeloma in adult patients who have received at least one prior therapy. Selinexor is also indicated...
Fedratinib	Fedratinib is indicated to treat adults with primary or secondary myelofibrosis that is either intermediate-2 or high risk.
Quizartinib	Quizartinib is under investigation in Childhood Acute Myeloid Leukemia/Other Myeloid Malignancies. It is a potent inhibitor of FLT3.
Pralsetinib	A RET receptor tyrosine kinase inhibitor for the treatment of metastatic RET-driven non-small cell lung cancer.
Tucatinib	A kinase inhibitor used to treat certain types of unresectable/metastatic HER-2 positive breast cancer.
Tirbanibulin	A tyrosine kinase and tubulin inhibitor used to treat actinic keratosis on the face or scalp.
Abagovomab	Abagovomab is under investigation in clinical trial NCT00418574 (Efficacy Multicentre Trial of Immunotherapy Vaccination With Abagovomab to Treat Ovarian Cancer Patients).
Magrolimab	Magrolimab is under investigation in clinical trial NCT02953782 (Trial of Magrolimab (Hu5f9-g4) in Combination With Cetuximab in Participants With Solid Tumors and Advanced Colorectal Cancer).
Nazartinib	Nazartinib is under investigation in clinical trial NCT03529084 (Phase III Study of Nazartinib (EGF816) Versus Erlotinib/gefitinib in First-line Locally Advanced / Metastatic NSCLC With EGFR Activating Mutations).
Pegylated Recombinant Human Arginase I	Pegylated Recombinant Human Arginase I is under investigation in clinical trial NCT03455140 (A Study Evaluating the Safety and Activity of Pegylated Recombinant Human Arginase (BCT-100)).
Polatuzumab vedotin	A CD79b antibody conjugate indicated to treat different types of large B-cell lymphoma.
Inbakicept	Not Available
Tepotinib	An oral tyrosine kinase inhibitor targeted against MET for the treatment of metastatic non-small cell lung cancer in patients exhibiting MET exon 14 skipping mutations.
Lisocabtagene maraleucel	A CAR T-cell therapy for treatment resistant or more severe B-cell lymphomas.
Ripretinib	A kinase inhibitor used to treat advanced gastrointestinal stromal tumor (GIST).
Umbralisib	A kinase inhibitor used to treat rare forms of refractory lymphoma.
Bacillus calmette-guerin substrain russian BCG-I live antigen	An intravesically-administered live BCG vaccine used to treat papillary urothelial cell carcinoma of the bladder.
Idecabtagene vicleucel	An autologous T-cell therapy indicated to treat relapsed or refractory multiple myeloma.
Dostarlimab	An anti-PD-1 monoclonal antibody used in the treatment of mismatch repair deficient endometrial cancers.
Sotorasib	An experimental KRAS inhibitor being investigated for the treatment of KRAS G12C mutant non small cell lung cancer, colorectal cancer, and appendix cancer.
Tisagenlecleucel	A CAR T cell therapy for relapsed or refractory large B-cell lymphoma and diffuse large B-cell lymphoma.
Trastuzumab deruxtecan	An antibody used to treat certain types of unresectable or metastatic HER-2 positive breast cancer.
Navtemadlin	Navtemadlin (AMG-232) is under investigation in clinical trial NCT03041688 (MDM2 Inhibitor AMG-232 and Decitabine in Treating Patients With Relapsed, Refractory, or Newly-Diagnosed Acute Myeloid Leukemia).
Belzutifan	An inhibitor of hypoxia-inducible factor 2α used as an antineoplastic in the treatment of certain cancers associated with von Hippel-Lindau (VHL) disease.
Tisotumab vedotin	A tissue factor-directed antibody drug conjugate that is used to treat adults with recurrent or metastatic cervical cancer with disease progression on or after chemotherapy.
Bortezomib D-mannitol	Not Annotated
Sacituzumab govitecan	Sacituzumab govitecan targets TROP-2-expressing cancer cells through a humanized antibody (RS7) before subsequently becoming internalized and releasing the topoisomerase I inhibitor SN-38 to induce DNA damage-mediated apoptosis.
Ipatasertib	Ipatasertib has been used in trials studying the treatment of Cancer, Neoplasms, Solid Cancers, Breast Cancer, and Gastric Cancer, among others.
Margetuximab	An Fc-engineered human/mouse chimeric IgG1κ anti-HER2 monoclonal antibody indicated for patients with HER2-positive metastatic breast cancer.
INCB-057643	INCB-057643 is under investigation in clinical trial NCT02959437 (Azacitidine Combined With Pembrolizumab and Epacadostat in Subjects With Advanced Solid Tumors (ECHO-206)).
Acetyldinaline	Acetyldinaline is under investigation in clinical trial NCT00005624 (CI-994 in Treating Patients With Advanced Myeloma).
Interferon alfa-2a	A form of recombinant human interferon used to stimulate the innate antiviral response in the treatment of hepatitis B and C viruses.
Ropidoxuridine	Investigated for use/treatment in cancer/tumors (unspecified).
Ulocuplumab	Ulocuplumab is under investigation in Solid Tumor.
Seviteronel	Seviteronel has been used in trials studying the treatment of CRPC, Prostate Cancer, and Castration-resistant Prostate Cancer.
Tacedinaline	Tacedinaline has been used in trials studying the treatment of Lung Cancer, Multiple Myeloma, and Pancreatic Cancer.
Futibatinib	A kinase inhibitor used to treat intrahepatic cholangiocarcinoma in previously treated adults.
Salvianolic acid A	Salvianolic acid A is under investigation in clinical trial NCT03908242 (Phase I Study of Continuous Administration of Salvianolic Acid A Tablet).
Ravoxertinib	Ravoxertinib is under investigation in clinical trial NCT01875705 (A Dose-Escalation Study of GDC-0994 in Patients With Locally Advanced or Metastatic Solid Tumors).
Xanthohumol	Xanthohumol is under investigation in clinical trial NCT01367431 (Xanthohumol and Metabolic Syndrome).
Teceleukin	Teceleukin is under investigation in clinical trial NCT03610490 (Autologous Tumor Infiltrating Lymphocytes MDA-TIL in Treating Patients With Recurrent or Refractory Ovarian Cancer, Osteosarcoma, or Pancreatic Ductal Adenocarcinoma).
Adagrasib	A KRAS inhibitor indicated for the treatment of locally advanced or metastatic KRAS G12C-mutated non-small cell lung cancer in patients who have received at least one prior systemic therapy.
Chiauranib	Chiauranib is under investigation in clinical trial NCT03974243 (Chiauranib in Combination With Chidamide in Patients With Relapsed/refractory Non-hodgkin's Lymphoma).
Felzartamab	Felzartamab is under investigation in clinical trial NCT04145440 (Trial to Assess Safety and Efficacy of MOR202 in Anti-pla2r + Membranous Nephropathy (Amn)).
Citarinostat	Citarinostat is under investigation in clinical trial NCT02886065 (A Study of PVX-410, a Cancer Vaccine, and Citarinostat +/- Lenalidomide for Smoldering MM).
Estramustine phosphate	A nitrogen mustard linked to estradiol, usually as phosphate; used to treat prostatic neoplasms; also has radiation protective properties.
Pamiparib	Pamiparib is under investigation in clinical trial NCT03933761 (Pamiparib in Fusion Positive, Reversion Negative High Grade Serous Ovarian Cancer or Carcinosarcoma With BRCA1/2 Gene Mutations If Progression on Substrate Poly...
Spartalizumab	Spartalizumab is under investigation in clinical trial NCT02605967 (Safety and Efficacy Study of PDR001 in Patients With Recurrent or Metastatic Nasopharyngeal Carcinoma).
Tislelizumab	Tislelizumab is under investigation in clinical trial NCT02660034 (The Safety, Pharmacokinetics and Antitumor Activity of BGB-A317 in Combination With BGB-290 in Subjects With Advanced Solid Tumors).
Bemarituzumab	Bemarituzumab is under investigation in clinical trial NCT03694522 (A Study of Bemarituzumab (FPA144) Combined With Modified FOLFOX6 (Mfolfox6) in Gastric/gastroesophageal Junction Cancer (FIGHT)).
Loncastuximab tesirine	An antibody-drug conjugate used for the treatment of relapsed and refractory B-cell lymphomas.
Amivantamab	An EGF and MET receptor targeted antibody indicated in the treatment of non-small cell lung cancer with an EGFR 20 exon insertion mutation.
Deacetoxyvinzolidine	Not Available
Tebentafusp	A bispecific gp100 peptide-HLA-directed CD3 T cell engager used to treat unresectable or metastatic uveal melanoma.
Lurbinectedin	A chemotherapeutic DNA alkylating agent used in the treatment of metastatic small-cell lung cancer.
Enfortumab vedotin	An antibody-drug conjugate comprised of a fully human monoclonal antibody and microtubule-disrupting chemotherapeutic agent used in the treatment of advanced or metastatic urothelial cancer.
Methyl 2,5-dihydroxycinnamate	Not Annotated
Mosunetuzumab	A humanized anti-CD20/CD3 bispecific antibody used to treat relapsed or refractory follicular lymphoma.
S-49076	Not Annotated
Cepharanthine	Not Annotated
Fadrozole	Not Annotated
Tanshinone I	Not Annotated
INCB-054329	Not Annotated
Oportuzumab monatox	Investigated for use/treatment in bladder cancer and head and neck cancer.
Selumetinib	A MEK 1/2 inhibitor used in pediatric patients to treat neurofibromatosis type 1 (NF1) accompanied by symptomatic, inoperable plexiform neurofibromas (PN).
Pacritinib	A kinase inhibitor used for the treatment of primary and secondary myelofibrosis in adult patients with significantly reduced platelet counts.
Duvelisib	An inhibitor of phosphatidylinositol 3-kinase delta and gamma used to treat relapsed or refractory chronic lymphocytic leukemia or small lymphocytic lymphoma.
Asciminib	An inhibitor of ABL/BCR-ABL1 tyrosine kinase for the treatment of patients with Philadelphia chromosome-positive CML, including those with the T315I mutation.
Tazemetostat	A methyltransferase inhibitor indicated to treat patients 16 years and older with metastatic or locally advanced epithelioid sarcoma not eligible for complete resection.
Tafasitamab	A CD19-directed cytolytic monoclonal antibody used in the treatment of B-cell malignancies.
Avapritinib	A selective tyrosine kinase inhibitor being investigated for the treatment of multidrug resistant gastrointestinal tumors.
Belantamab mafodotin	An anti B-cell maturation antigen antibody conjugated to a microtubule inhibitor to treat relapsed or refractory multiple myeloma.
Retifanlimab	Not Annotated
Trastuzumab duocarmazine	Trastuzumab duocarmazine is under investigation in clinical trial NCT03262935 (SYD985 vs. Physician's Choice in Participants With Her2-positive Locally Advanced or Metastatic Breast Cancer).
Melphalan flufenamide	A melphalan prodrug used to treat relapsed or refractory multiple myeloma.
Prolgolimab	Not Annotated
Chelerythrine	A benzophenanthridine alkaloid evaluated as a kinase-inhibitor.
Ellipticine	Ellipticine is a potent antineoplastic agent.
Plumbagin	Plumbagin is a compound investigated for its anticancer activity. It has been found that it inactivates the Akt/NF-kB, MMP-9 and VEGF pathways.
Scriptaid	Scriptaid is a histone deacetylase (HDAC) inhibitor researched for its anti-tumor properties.
Mirvetuximab soravtansine	A folate receptor alpha-directed antibody and microtubule inhibitor conjugate used to treat folate receptor alpha positive, platinum-resistant epithelial ovarian, fallopian tube, or primary peritoneal cancer.
NRC-AN-019	Not Annotated
Ukrain cation	Not Annotated
5,6-dihydro-5-azacytidine	Not Annotated
Diaziquone	Not Annotated
Cantuzumab mertansine	Not Annotated
Bisantrene	Not Annotated
Minnelide free acid	Not Annotated
Minnelide	Not Annotated
Aroplatin	Not Annotated
BI 836826	Not Annotated
Olutasidenib	An isocitrate dehydrogenase-1 (IDH1) inhibitor indicated for the treatment of patients with relapsed or refractory acute myeloid leukemia with a susceptible IDH1 mutation as detected by an FDA-approved test.
Zanolimumab	Zanolimumab is a fully human monoclonal antibody directed against CD4.
Nadofaragene firadenovec	A non-replicating adenoviral vector-based gene therapy used to treat high-risk Bacillus Calmette-Guérin (BCG)-unresponsive non-muscle invasive bladder cancer (NMIBC) with carcinoma in situ (CIS).
Vinblastine N-oxide	Not Available

Drugs & Drug Targets

Drug	Target	Type
Cetuximab	Epidermal growth factor receptor	target
Cetuximab	Low affinity immunoglobulin gamma Fc region receptor III-B	target
Cetuximab	Complement C1q subcomponent subunit A	target
Cetuximab	Complement C1q subcomponent subunit B	target
Cetuximab	Complement C1q subcomponent subunit C	target
Cetuximab	Low affinity immunoglobulin gamma Fc region receptor III-A	target
Cetuximab	High affinity immunoglobulin gamma Fc receptor I	target
Cetuximab	Low affinity immunoglobulin gamma Fc region receptor II-a	target
Denileukin diftitox	Interleukin-2 receptor subunit alpha	target
Denileukin diftitox	Cytokine receptor common subunit gamma	target
Denileukin diftitox	Interleukin-2 receptor subunit beta	target
Asparaginase Escherichia coli	L-asparagine	target
Asparaginase Escherichia coli	Thyroxine-binding globulin	carrier
Pegaspargase	L-asparagine	target
Pegaspargase	Thyroxine-binding globulin	carrier
Trastuzumab	Receptor tyrosine-protein kinase erbB-2	target
Rituximab	B-lymphocyte antigen CD20	target
Bevacizumab	Vascular endothelial growth factor A	target
Bevacizumab	Complement C1q subcomponent subunit A	target
Bevacizumab	Complement C1q subcomponent subunit B	target
Bevacizumab	Complement C1q subcomponent subunit C	target
Bevacizumab	Low affinity immunoglobulin gamma Fc region receptor III-A	target
Bevacizumab	Low affinity immunoglobulin gamma Fc region receptor II-a	target
Bevacizumab	Low affinity immunoglobulin gamma Fc region receptor II-b	target
Bevacizumab	Low affinity immunoglobulin gamma Fc region receptor II-c	target
Bevacizumab	High affinity immunoglobulin gamma Fc receptor I	target
Bortezomib	Cytochrome P450 3A4	enzyme
Bortezomib	Cytochrome P450 2C19	enzyme
Bortezomib	Cytochrome P450 1A2	enzyme
Bortezomib	Cytochrome P450 2D6	enzyme
Bortezomib	Cytochrome P450 2C9	enzyme
Bortezomib	Proteasome subunit beta type-5	target
Bortezomib	Proteasome subunit beta type-1	target
Bortezomib	P-glycoprotein 1	transporter
Bortezomib	Solute carrier organic anion transporter family member 1B3	transporter
Pipobroman	DNA	target
Cladribine	Purine nucleoside phosphorylase	target
Cladribine	DNA	target
Cladribine	Deoxycytidine kinase	enzyme
Cladribine	Ribonucleoside-diphosphate reductase large subunit	target
Cladribine	Ribonucleoside-diphosphate reductase subunit M2	target
Cladribine	Ribonucleoside-diphosphate reductase subunit M2 B	target
Cladribine	DNA polymerase alpha catalytic subunit	target
Cladribine	DNA polymerase epsilon catalytic subunit A	target
Cladribine	DNA polymerase epsilon subunit 2	target
Cladribine	DNA polymerase epsilon subunit 3	target
Cladribine	DNA polymerase epsilon subunit 4	target
Cladribine	ATP-binding cassette sub-family G member 2	transporter
Cladribine	Solute carrier family 28 member 3	transporter
Carmustine	Glutathione reductase, mitochondrial	target
Carmustine	DNA	target
Carmustine	RNA	target
Amsacrine	DNA topoisomerase 2-alpha	target
Amsacrine	DNA	target
Amsacrine	Potassium voltage-gated channel subfamily H member 2	target
Amsacrine	P-glycoprotein 1	transporter
Amsacrine	Alpha-1-acid glycoprotein 1	target
Amsacrine	Serum albumin	target
Bleomycin	DNA ligase 3	target
Bleomycin	DNA ligase 1	target
Bleomycin	DNA	target
Bleomycin	Bleomycin hydrolase	enzyme
Chlorambucil	DNA	target
Chlorambucil	Glutathione S-transferase P	enzyme
Chlorambucil	Solute carrier organic anion transporter family member 1A2	transporter
Chlorambucil	Glutathione S-transferases (Cytosolic)	enzyme
Raltitrexed	Thymidylate synthase	target
Raltitrexed	Folylpolyglutamate synthase, mitochondrial	target
Mitomycin	DNA	target
Mitomycin	NADPH--cytochrome P450 reductase	enzyme
Bexarotene	Retinoic acid receptor RXR-beta	target
Bexarotene	Cytochrome P450 3A4	enzyme
Bexarotene	Retinoic acid receptor RXR-alpha	target
Bexarotene	Retinoic acid receptor RXR-gamma	target
Bexarotene	Cytochrome P450 2C8	enzyme
Vindesine	Tubulin beta-1 chain	target
Vindesine	Cytochrome P450 3A4	enzyme
Gefitinib	Epidermal growth factor receptor	target
Gefitinib	Cytochrome P450 3A4	enzyme
Gefitinib	Cytochrome P450 2D6	enzyme
Gefitinib	P-glycoprotein 1	transporter
Gefitinib	ATP-binding cassette sub-family G member 2	transporter
Gefitinib	Cytochrome P450 3A5	enzyme
Gefitinib	Cytochrome P450 1A1	enzyme
Gefitinib	Cytochrome P450 2C9	enzyme
Gefitinib	Cytochrome P450 2C19	enzyme
Gefitinib	Serum albumin	carrier
Gefitinib	Alpha-1-acid glycoprotein 1	carrier
Tioguanine	DNA	target
Tioguanine	Multidrug resistance-associated protein 4	transporter
Tioguanine	Hypoxanthine-guanine phosphoribosyltransferase	enzyme
Vinorelbine	Tubulin beta chain	target
Vinorelbine	Cytochrome P450 3A4	enzyme
Vinorelbine	Cytochrome P450 2D6	enzyme
Valrubicin	DNA topoisomerase 2-alpha	target
Valrubicin	DNA	target
Sorafenib	Serine/threonine-protein kinase B-raf	target
Sorafenib	Receptor-type tyrosine-protein kinase FLT3	target
Sorafenib	RAF proto-oncogene serine/threonine-protein kinase	target
Sorafenib	Vascular endothelial growth factor receptor 3	target
Sorafenib	Platelet-derived growth factor receptor beta	target
Sorafenib	Mast/stem cell growth factor receptor Kit	target
Sorafenib	Vascular endothelial growth factor receptor 2	target
Sorafenib	Cytochrome P450 3A4	enzyme
Sorafenib	UDP-glucuronosyltransferase 1-9	enzyme
Sorafenib	Cytochrome P450 2B6	enzyme
Sorafenib	Cytochrome P450 2C8	enzyme
Sorafenib	Cytochrome P450 3A5	enzyme
Sorafenib	Cytochrome P450 3A7	enzyme
Sorafenib	Cytochrome P450 2C9	enzyme
Sorafenib	Multidrug resistance-associated protein 4	transporter
Sorafenib	P-glycoprotein 1	transporter
Sorafenib	Canalicular multispecific organic anion transporter 1	transporter
Sorafenib	ATP-binding cassette sub-family G member 2	transporter
Sorafenib	Cytochrome P450 1A2	enzyme
Sorafenib	Cytochrome P450 2C19	enzyme
Sorafenib	Cytochrome P450 2D6	enzyme
Sorafenib	UDP-glucuronosyltransferase 1-1	enzyme
Sorafenib	RalA-binding protein 1	transporter
Sorafenib	Fibroblast growth factor receptor 1	target
Sorafenib	Proto-oncogene tyrosine-protein kinase receptor Ret	target
Sorafenib	Vascular endothelial growth factor receptor 1	target
Sorafenib	Solute carrier organic anion transporter family member 1B1	transporter
Streptozocin	DNA	target
Streptozocin	P-glycoprotein 1	transporter
Streptozocin	Solute carrier family 2, facilitated glucose transporter member 2	target
Streptozocin	O-GlcNAcase BT_4395	target
Streptozocin	Cytochrome P450 1A1	enzyme
Streptozocin	Cytochrome P450 1A2	enzyme
Streptozocin	Cytochrome P450 2E1	enzyme
Streptozocin	Bifunctional protein NCOAT	target
Gemcitabine	Ribonucleoside-diphosphate reductase large subunit	target
Gemcitabine	UMP-CMP kinase	target
Gemcitabine	Thymidylate synthase	target
Gemcitabine	Cytidine deaminase	enzyme
Gemcitabine	Deoxycytidine kinase	enzyme
Gemcitabine	P-glycoprotein 1	transporter
Gemcitabine	Multidrug resistance-associated protein 7	transporter
Gemcitabine	Equilibrative nucleoside transporter 1	transporter
Gemcitabine	DNA	target
Gemcitabine	Sodium/nucleoside cotransporter 1	transporter
Gemcitabine	Equilibrative nucleoside transporter 2	transporter
Gemcitabine	Solute carrier family 28 member 3	transporter
Gemcitabine	Thymidine kinase 2, mitochondrial	enzyme
Gemcitabine	UMP-CMP kinase	enzyme
Gemcitabine	Nucleoside diphosphate kinase A	enzyme
Teniposide	DNA topoisomerase 2-alpha	target
Teniposide	Cytochrome P450 2C19	enzyme
Teniposide	Cytochrome P450 2C9	enzyme
Teniposide	Cytochrome P450 3A4	enzyme
Teniposide	Multidrug resistance-associated protein 6	transporter
Teniposide	ATP-binding cassette sub-family G member 2	transporter
Teniposide	Cytochrome P450 3A5	enzyme
Epirubicin	DNA topoisomerase 2-alpha	target
Epirubicin	DNA	target
Epirubicin	Multidrug resistance-associated protein 1	transporter
Epirubicin	UDP-glucuronosyltransferase 2B7	enzyme
Epirubicin	Cytosolic phospholipase A2	enzyme
Altretamine	DNA	target
Cisplatin	DNA	target
Cisplatin	Canalicular multispecific organic anion transporter 2	transporter
Cisplatin	Multidrug resistance-associated protein 5	transporter
Cisplatin	Canalicular multispecific organic anion transporter 1	transporter
Cisplatin	Solute carrier family 22 member 2	transporter
Cisplatin	High affinity copper uptake protein 1	transporter
Cisplatin	Probable low affinity copper uptake protein 2	transporter
Cisplatin	Multidrug resistance-associated protein 6	transporter
Cisplatin	Copper-transporting ATPase 2	transporter
Cisplatin	Copper-transporting ATPase 1	transporter
Cisplatin	Prostaglandin G/H synthase 2	enzyme
Cisplatin	Myeloperoxidase	enzyme
Cisplatin	Xanthine dehydrogenase/oxidase	enzyme
Cisplatin	Arylamine N-acetyltransferase	enzyme
Cisplatin	Cytochrome P450 2C9	enzyme
Cisplatin	Cytochrome P450 2B6	enzyme
Cisplatin	Cholinesterase	enzyme
Cisplatin	Cytochrome P450 4A11	enzyme
Cisplatin	ATP-binding cassette sub-family G member 2	transporter
Cisplatin	Glutathione S-transferase theta-1	enzyme
Cisplatin	Metallothionein-1A	enzyme
Cisplatin	Metallothionein-2	enzyme
Cisplatin	Superoxide dismutase [Cu-Zn]	enzyme
Cisplatin	Glutathione S-transferase P	enzyme
Cisplatin	NAD(P)H dehydrogenase [quinone] 1	enzyme
Cisplatin	Glutathione S-transferase Mu 1	enzyme
Cisplatin	DNA-3-methyladenine glycosylase	target
Cisplatin	Alpha-2-macroglobulin	target
Cisplatin	Serum albumin	carrier
Cisplatin	Serotransferrin	target
Cisplatin	Copper transport protein ATOX1	target
Alitretinoin	Retinoic acid receptor alpha	target
Alitretinoin	Retinoic acid receptor RXR-beta	target
Alitretinoin	Retinoic acid receptor gamma	target
Alitretinoin	Retinoic acid receptor beta	target
Alitretinoin	Retinoic acid receptor RXR-gamma	target
Alitretinoin	Retinoic acid receptor RXR-alpha	target
Alitretinoin	Cellular retinoic acid-binding protein 2	carrier
Alitretinoin	Cellular retinoic acid-binding protein 1	carrier
Alitretinoin	P-glycoprotein 1	transporter
Alitretinoin	Insulin-like growth factor-binding protein 3	target
Alitretinoin	Pregnancy-specific beta-1-glycoprotein 5	target
Alitretinoin	Cytochrome P450 26C1	target
Oxaliplatin	DNA	target
Oxaliplatin	Solute carrier family 22 member 2	transporter
Oxaliplatin	High affinity copper uptake protein 1	transporter
Oxaliplatin	Solute carrier family 22 member 3	transporter
Oxaliplatin	ATP-binding cassette sub-family G member 2	transporter
Oxaliplatin	Glutathione S-transferase theta-1	enzyme
Oxaliplatin	Metallothionein-1A	enzyme
Oxaliplatin	Metallothionein-2	enzyme
Oxaliplatin	Myeloperoxidase	enzyme
Oxaliplatin	Superoxide dismutase [Cu-Zn]	enzyme
Oxaliplatin	Glutathione S-transferase P	enzyme
Oxaliplatin	Glutathione S-transferase Mu 1	enzyme
Oxaliplatin	NAD(P)H dehydrogenase [quinone] 1	enzyme
Oxaliplatin	Canalicular multispecific organic anion transporter 1	transporter
Oxaliplatin	Copper-transporting ATPase 2	transporter
Oxaliplatin	Copper-transporting ATPase 1	transporter
Erlotinib	Epidermal growth factor receptor	target
Erlotinib	Cytochrome P450 3A4	enzyme
Erlotinib	ATP-binding cassette sub-family G member 2	transporter
Erlotinib	P-glycoprotein 1	transporter
Erlotinib	Nuclear receptor subfamily 1 group I member 2	target
Erlotinib	Cytochrome P450 3A5	enzyme
Erlotinib	Cytochrome P450 1A1	enzyme
Erlotinib	Cytochrome P450 1A2	enzyme
Erlotinib	Cytochrome P450 1B1	enzyme
Erlotinib	Cytochrome P450 2D6	enzyme
Erlotinib	Cytochrome P450 2C8	enzyme
Erlotinib	UDP-glucuronosyltransferase 1-1	enzyme
Erlotinib	Serum albumin	carrier
Erlotinib	Alpha-1-acid glycoprotein 1	carrier
Erlotinib	Solute carrier organic anion transporter family member 2B1	transporter
Erlotinib	Epidermal growth factor receptor	enzyme
Cyclophosphamide	DNA	target
Cyclophosphamide	Cytochrome P450 2B6	enzyme
Cyclophosphamide	Cytochrome P450 2C9	enzyme
Cyclophosphamide	Cytochrome P450 3A4	enzyme
Cyclophosphamide	Cytochrome P450 2C19	enzyme
Cyclophosphamide	Cytochrome P450 2A6	enzyme
Cyclophosphamide	Cytochrome P450 2C18	enzyme
Cyclophosphamide	Cytochrome P450 2C8	enzyme
Cyclophosphamide	Cytochrome P450 3A5	enzyme
Cyclophosphamide	Nuclear receptor subfamily 1 group I member 2	target
Vincristine	Tubulin beta chain	target
Vincristine	Cytochrome P450 3A4	enzyme
Vincristine	Cytochrome P450 3A5	enzyme
Vincristine	Cytochrome P450 3A7	enzyme
Vincristine	P-glycoprotein 1	transporter
Vincristine	Canalicular multispecific organic anion transporter 2	transporter
Vincristine	Solute carrier family 22 member 3	transporter
Vincristine	Multidrug resistance-associated protein 1	transporter
Vincristine	Multidrug resistance-associated protein 7	transporter
Vincristine	Canalicular multispecific organic anion transporter 1	transporter
Vincristine	Bile salt export pump	transporter
Vincristine	ATP-binding cassette sub-family G member 2	transporter
Vincristine	Tubulin alpha-4A chain	target
Vincristine	RalA-binding protein 1	transporter
Vincristine	Solute carrier organic anion transporter family member 1B1	transporter
Vincristine	Solute carrier organic anion transporter family member 1B3	transporter
Fluorouracil	Thymidylate synthase	target
Fluorouracil	Cytochrome P450 1A2	enzyme
Fluorouracil	Thymidine phosphorylase	enzyme
Fluorouracil	Serum albumin	carrier
Fluorouracil	Cytochrome P450 2C9	enzyme
Fluorouracil	Dihydropyrimidine dehydrogenase [NADP(+)]	enzyme
Fluorouracil	Uridine phosphorylase 1	enzyme
Fluorouracil	Uridine phosphorylase 2	enzyme
Fluorouracil	DNA	target
Fluorouracil	RNA	target
Fluorouracil	Cytochrome P450 2A6	enzyme
Fluorouracil	Cytochrome P450 2C8	enzyme
Fluorouracil	Methylenetetrahydrofolate reductase	enzyme
Fluorouracil	Thymidylate synthase	enzyme
Fluorouracil	Uridine 5'-monophosphate synthase	enzyme
Fluorouracil	Amidophosphoribosyltransferase	enzyme
Fluorouracil	Solute carrier family 22 member 7	transporter
Fluorouracil	Equilibrative nucleoside transporter 1	transporter
Fluorouracil	ATP-binding cassette sub-family G member 2	transporter
Fluorouracil	Canalicular multispecific organic anion transporter 2	transporter
Fluorouracil	Multidrug resistance-associated protein 4	transporter
Fluorouracil	Multidrug resistance-associated protein 5	transporter
Fluorouracil	Thyroxine-binding globulin	carrier
Pentostatin	Adenosine deaminase	target
Methotrexate	Dihydrofolate reductase	target
Methotrexate	Aldehyde oxidase	enzyme
Methotrexate	Methylenetetrahydrofolate reductase	enzyme
Methotrexate	Serum albumin	carrier
Methotrexate	Canalicular multispecific organic anion transporter 2	transporter
Methotrexate	Multidrug resistance-associated protein 4	transporter
Methotrexate	Multidrug resistance-associated protein 1	transporter
Methotrexate	Solute carrier family 22 member 6	transporter
Methotrexate	Multidrug resistance-associated protein 7	transporter
Methotrexate	Solute carrier family 22 member 8	transporter
Methotrexate	Canalicular multispecific organic anion transporter 1	transporter
Methotrexate	P-glycoprotein 1	transporter
Methotrexate	Solute carrier organic anion transporter family member 1A2	transporter
Methotrexate	Monocarboxylate transporter 1	transporter
Methotrexate	ATP-binding cassette sub-family C member 11	transporter
Methotrexate	Solute carrier organic anion transporter family member 1B3	transporter
Methotrexate	Solute carrier family 22 member 11	transporter
Methotrexate	Solute carrier organic anion transporter family member 1C1	transporter
Methotrexate	Solute carrier organic anion transporter family member 3A1	transporter
Methotrexate	ATP-binding cassette sub-family G member 2	transporter
Methotrexate	Solute carrier family 22 member 7	transporter
Methotrexate	Solute carrier organic anion transporter family member 1B1	transporter
Methotrexate	6-phosphogluconate dehydrogenase, decarboxylating	enzyme
Methotrexate	Proton-coupled folate transporter	transporter
Methotrexate	Folylpolyglutamate synthase, mitochondrial	enzyme
Methotrexate	Gamma-glutamyl hydrolase	enzyme
Methotrexate	Dihydrofolate reductase	enzyme
Methotrexate	Thymidylate synthase	enzyme
Methotrexate	Bifunctional purine biosynthesis protein PURH	enzyme
Methotrexate	Solute carrier organic anion transporter family member 4C1	transporter
Methotrexate	Folate transporter 1	transporter
Methotrexate	Folate receptor alpha	transporter
Methotrexate	Cytochrome P450 3A4	enzyme
Methotrexate	Thymidylate synthase	target
Methotrexate	Bifunctional purine biosynthesis protein PURH	target
Methotrexate	Folate receptor beta	transporter
Methotrexate	Solute carrier family 15 member 1	transporter
Methotrexate	Proton-coupled amino acid transporter 1	transporter
Methotrexate	Carboxypeptidase G2	enzyme
Vinblastine	Tubulin beta chain	target
Vinblastine	Transcription factor AP-1	target
Vinblastine	Cytochrome P450 3A4	enzyme
Vinblastine	P-glycoprotein 1	transporter
Vinblastine	Multidrug resistance-associated protein 1	transporter
Vinblastine	Canalicular multispecific organic anion transporter 1	transporter
Vinblastine	Multidrug resistance-associated protein 6	transporter
Vinblastine	Bile salt export pump	transporter
Vinblastine	Tubulin alpha-1A chain	target
Vinblastine	Tubulin delta chain	target
Vinblastine	Tubulin epsilon chain	target
Vinblastine	Tubulin gamma-1 chain	target
Vinblastine	Cytochrome P450 2D6	enzyme
Vinblastine	Solute carrier organic anion transporter family member 1B1	transporter
Imatinib	Platelet-derived growth factor receptor beta	target
Imatinib	Tyrosine-protein kinase ABL1	target
Imatinib	Mast/stem cell growth factor receptor Kit	target
Imatinib	RET proto-oncogene	target
Imatinib	High affinity nerve growth factor receptor	target
Imatinib	Macrophage colony-stimulating factor 1 receptor	target
Imatinib	Platelet-derived growth factor receptor alpha	target
Imatinib	Epithelial discoidin domain-containing receptor 1	target
Imatinib	Cytochrome P450 3A4	enzyme
Imatinib	Breakpoint cluster region protein	target
Imatinib	Cytochrome P450 1A2	enzyme
Imatinib	Cytochrome P450 2D6	enzyme
Imatinib	Cytochrome P450 2C9	enzyme
Imatinib	Cytochrome P450 2C19	enzyme
Imatinib	Cytochrome P450 3A5	enzyme
Imatinib	Cytochrome P450 3A7	enzyme
Imatinib	Solute carrier family 22 member 1	transporter
Imatinib	P-glycoprotein 1	transporter
Imatinib	Solute carrier family 22 member 2	transporter
Imatinib	ATP-binding cassette sub-family G member 2	transporter
Imatinib	ATP-binding cassette sub-family A member 3	transporter
Imatinib	Serum albumin	carrier
Imatinib	Alpha-1-acid glycoprotein 1	carrier
Imatinib	Bile salt export pump	transporter
Imatinib	Cytochrome P450 2C8	enzyme
Imatinib	Canalicular multispecific organic anion transporter 1	transporter
Imatinib	Multidrug resistance-associated protein 1	transporter
Imatinib	Solute carrier family 22 member 5	transporter
Imatinib	Solute carrier organic anion transporter family member 1B3	transporter
Imatinib	Multidrug resistance-associated protein 4	transporter
Imatinib	Solute carrier organic anion transporter family member 1A2	transporter
Imatinib	Discoidin domain-containing receptor 2	target
Clofarabine	DNA polymerase alpha catalytic subunit	target
Clofarabine	Ribonucleoside-diphosphate reductase large subunit	target
Clofarabine	Deoxycytidine kinase	enzyme
Clofarabine	DNA	target
Clofarabine	ATP-binding cassette sub-family G member 2	transporter
Pemetrexed	Thymidylate synthase	target
Pemetrexed	Dihydrofolate reductase	target
Pemetrexed	Trifunctional purine biosynthetic protein adenosine-3	target
Pemetrexed	Deoxycytidine kinase	enzyme
Pemetrexed	Bifunctional purine biosynthesis protein PURH	target
Pemetrexed	Equilibrative nucleoside transporter 1	enzyme
Pemetrexed	Solute carrier family 22 member 8	transporter
Pemetrexed	Folate transporter 1	transporter
Pemetrexed	Proton-coupled folate transporter	transporter
Pemetrexed	ATP-binding cassette sub-family G member 2	transporter
Pemetrexed	Multidrug resistance-associated protein 5	transporter
Pemetrexed	Solute carrier family 22 member 6	transporter
Pemetrexed	Serum albumin	carrier
Pemetrexed	Solute carrier family 22 member 11	transporter
Mitotane	Cytochrome P450 11B1, mitochondrial	target
Mitotane	Adrenodoxin, mitochondrial	target
Mitotane	Sex hormone-binding globulin	carrier
Mitotane	Corticosteroid-binding globulin	carrier
Mitotane	Cytochrome P450 3A4	enzyme
Mitotane	Estrogen receptor alpha	target
Mitotane	Progesterone receptor	target
Mitotane	Androgen receptor	target
Mitotane	Thyroxine-binding globulin	carrier
Mitotane	P-glycoprotein 1	transporter
Daunorubicin	DNA	target
Daunorubicin	Cytochrome P450 3A5	enzyme
Daunorubicin	NADPH--cytochrome P450 reductase	enzyme
Daunorubicin	P-glycoprotein 1	transporter
Daunorubicin	Multidrug resistance-associated protein 1	transporter
Daunorubicin	Multidrug resistance-associated protein 6	transporter
Daunorubicin	Multidrug resistance-associated protein 7	transporter
Daunorubicin	ATP-binding cassette sub-family G member 2	transporter
Daunorubicin	DNA topoisomerase 2-alpha	target
Daunorubicin	DNA topoisomerase 2-beta	target
Daunorubicin	Cytochrome P450 1B1	enzyme
Daunorubicin	Cytochrome P450 3A4	enzyme
Daunorubicin	Aldose reductase	enzyme
Daunorubicin	Carbonyl reductase [NADPH] 1	enzyme
Daunorubicin	Carbonyl reductase [NADPH] 3	enzyme
Porfimer sodium	Low-density lipoprotein receptor	target
Porfimer sodium	High affinity immunoglobulin gamma Fc receptor I	target
Irinotecan	DNA topoisomerase I, mitochondrial	target
Irinotecan	DNA topoisomerase 1	target
Irinotecan	Cytochrome P450 3A4	enzyme
Irinotecan	Cytochrome P450 3A5	enzyme
Irinotecan	UDP-glucuronosyltransferase 1-1	enzyme
Irinotecan	UDP-glucuronosyltransferase 1-9	enzyme
Irinotecan	Liver carboxylesterase 1	enzyme
Irinotecan	Cytochrome P450 3A7	enzyme
Irinotecan	Cytochrome P450 2B6	enzyme
Irinotecan	Solute carrier family 22 member 3	transporter
Irinotecan	Solute carrier organic anion transporter family member 1B1	transporter
Irinotecan	Multidrug resistance-associated protein 1	transporter
Irinotecan	ATP-binding cassette sub-family G member 2	transporter
Irinotecan	Serum albumin	carrier
Irinotecan	Cocaine esterase	enzyme
Irinotecan	Cholinesterase	enzyme
Irinotecan	P-glycoprotein 1	transporter
Irinotecan	Canalicular multispecific organic anion transporter 1	transporter
Etoposide	DNA topoisomerase 2-alpha	target
Etoposide	Cytochrome P450 3A4	enzyme
Etoposide	Canalicular multispecific organic anion transporter 2	transporter
Etoposide	Multidrug resistance-associated protein 6	transporter
Etoposide	P-glycoprotein 1	transporter
Etoposide	Multidrug resistance-associated protein 1	transporter
Etoposide	Multidrug resistance-associated protein 7	transporter
Etoposide	Canalicular multispecific organic anion transporter 1	transporter
Etoposide	ATP-binding cassette sub-family G member 2	transporter
Etoposide	Cytochrome P450 1A2	enzyme
Etoposide	Cytochrome P450 2E1	enzyme
Etoposide	Cytochrome P450 3A5	enzyme
Etoposide	UDP-glucuronosyltransferase 1-1	enzyme
Etoposide	DNA topoisomerase 2-beta	target
Etoposide	Glutathione S-transferase theta-1	enzyme
Etoposide	Glutathione S-transferase P	enzyme
Etoposide	Prostaglandin G/H synthase 2	enzyme
Etoposide	Prostaglandin G/H synthase 1	enzyme
Dacarbazine	DNA polymerase alpha subunit B	target
Dacarbazine	Cytochrome P450 1A1	enzyme
Dacarbazine	Cytochrome P450 1A2	enzyme
Dacarbazine	Cytochrome P450 2E1	enzyme
Dacarbazine	6-phosphogluconate dehydrogenase, decarboxylating	target
Dacarbazine	DNA	target
Temozolomide	DNA	target
Temozolomide	Serum albumin	carrier
Temozolomide	Alpha-1-acid glycoprotein 1	carrier
Temozolomide	P-glycoprotein 1	transporter
Temozolomide	ATP-binding cassette sub-family G member 2	transporter
Mechlorethamine	DNA	target
Mechlorethamine	Cholinesterase	enzyme
Azacitidine	DNA (cytosine-5)-methyltransferase 1	target
Azacitidine	Cytidine deaminase	enzyme
Azacitidine	DNA	target
Azacitidine	RNA	target
Carboplatin	DNA	target
Carboplatin	High affinity copper uptake protein 1	transporter
Carboplatin	Probable low affinity copper uptake protein 2	transporter
Carboplatin	Xanthine dehydrogenase/oxidase	enzyme
Carboplatin	Myeloperoxidase	enzyme
Carboplatin	Glutathione S-transferase theta-1	enzyme
Carboplatin	Metallothionein-1A	enzyme
Carboplatin	Metallothionein-2	enzyme
Carboplatin	Superoxide dismutase [Cu-Zn]	enzyme
Carboplatin	Glutathione S-transferase P	enzyme
Carboplatin	Glutathione S-transferase Mu 1	enzyme
Carboplatin	NAD(P)H dehydrogenase [quinone] 1	enzyme
Carboplatin	Copper-transporting ATPase 1	transporter
Carboplatin	Copper-transporting ATPase 2	transporter
Carboplatin	ATP-binding cassette sub-family G member 2	transporter
Carboplatin	Canalicular multispecific organic anion transporter 1	transporter
Dactinomycin	DNA	target
Dactinomycin	Solute carrier family 22 member 5	transporter
Dactinomycin	P-glycoprotein 1	transporter
Dactinomycin	Multidrug resistance-associated protein 6	transporter
Dactinomycin	Multidrug resistance-associated protein 1	transporter
Dactinomycin	ATP-binding cassette sub-family G member 2	transporter
Dactinomycin	DNA topoisomerase 2	target
Dactinomycin	DNA topoisomerase 1	target
Cytarabine	DNA polymerase beta	target
Cytarabine	Cytidine deaminase	enzyme
Cytarabine	Solute carrier family 22 member 4	transporter
Cytarabine	Multidrug resistance-associated protein 7	transporter
Cytarabine	Equilibrative nucleoside transporter 1	transporter
Cytarabine	DNA	target
Cytarabine	Cytochrome P450 3A4	enzyme
Cytarabine	Deoxycytidine kinase	enzyme
Cytarabine	5'-nucleotidase	enzyme
Cytarabine	Deoxycytidylate deaminase	enzyme
Doxorubicin	DNA topoisomerase 2-alpha	target
Doxorubicin	DNA	target
Doxorubicin	Cytochrome P450 3A4	enzyme
Doxorubicin	Cytochrome P450 2D6	enzyme
Doxorubicin	Cytochrome P450 2B6	enzyme
Doxorubicin	P-glycoprotein 1	transporter
Doxorubicin	Canalicular multispecific organic anion transporter 2	transporter
Doxorubicin	Multidrug resistance-associated protein 6	transporter
Doxorubicin	Multidrug resistance-associated protein 1	transporter
Doxorubicin	Multidrug resistance-associated protein 7	transporter
Doxorubicin	ATP-binding cassette sub-family G member 2	transporter
Doxorubicin	Bile salt export pump	transporter
Doxorubicin	Solute carrier family 22 member 16	transporter
Doxorubicin	ATP-binding cassette sub-family B member 8, mitochondrial	transporter
Doxorubicin	Cytochrome P450 1B1	enzyme
Doxorubicin	Carbonyl reductase [NADPH] 1	enzyme
Doxorubicin	Carbonyl reductase [NADPH] 3	enzyme
Doxorubicin	Alcohol dehydrogenase [NADP(+)]	enzyme
Doxorubicin	Aldo-keto reductase family 1 member C3	enzyme
Doxorubicin	NAD(P)H dehydrogenase [quinone] 1	enzyme
Doxorubicin	Xanthine dehydrogenase/oxidase	enzyme
Doxorubicin	Nitric oxide synthase, endothelial	enzyme
Doxorubicin	Nitric oxide synthase, inducible	enzyme
Doxorubicin	Nitric oxide synthase, brain	enzyme
Doxorubicin	NADH dehydrogenase [ubiquinone] iron-sulfur protein 2, mitochondrial	enzyme
Doxorubicin	NADH dehydrogenase [ubiquinone] iron-sulfur protein 3, mitochondrial	enzyme
Doxorubicin	NADH dehydrogenase [ubiquinone] iron-sulfur protein 7, mitochondrial	enzyme
Doxorubicin	NADPH--cytochrome P450 reductase	enzyme
Doxorubicin	RalA-binding protein 1	transporter
Doxorubicin	Canalicular multispecific organic anion transporter 1	transporter
Doxorubicin	Serum albumin	carrier
Doxorubicin	Nucleolar and coiled-body phosphoprotein 1	target
Doxorubicin	DNA topoisomerase 1	target
Doxorubicin	DNA topoisomerase 2-beta	target
Hydroxyurea	Ribonucleoside-diphosphate reductase large subunit	target
Hydroxyurea	Cytochrome P450 2D6	enzyme
Busulfan	DNA	target
Busulfan	Cytochrome P450 3A4	enzyme
Busulfan	Glutathione S-transferase A2	enzyme
Busulfan	Glutathione S-transferase A1	enzyme
Busulfan	Glutathione S-transferase Mu 1	enzyme
Busulfan	Glutathione S-transferase P	enzyme
Busulfan	Microsomal glutathione S-transferase 2	enzyme
Topotecan	DNA topoisomerase I, mitochondrial	target
Topotecan	DNA topoisomerase 1	target
Topotecan	ATP-binding cassette sub-family G member 2	transporter
Topotecan	P-glycoprotein 1	transporter
Topotecan	DNA	target
Topotecan	Multidrug and toxin extrusion protein 1	transporter
Topotecan	Multidrug and toxin extrusion protein 2	transporter
Mercaptopurine	Thiopurine S-methyltransferase	enzyme
Mercaptopurine	Xanthine dehydrogenase/oxidase	enzyme
Mercaptopurine	Hypoxanthine-guanine phosphoribosyltransferase	target
Mercaptopurine	Solute carrier family 22 member 8	transporter
Mercaptopurine	Multidrug resistance-associated protein 4	transporter
Mercaptopurine	Multidrug resistance-associated protein 5	transporter
Mercaptopurine	Sodium/nucleoside cotransporter 2	transporter
Mercaptopurine	Solute carrier family 28 member 3	transporter
Mercaptopurine	Equilibrative nucleoside transporter 1	transporter
Mercaptopurine	Equilibrative nucleoside transporter 2	transporter
Mercaptopurine	Aldehyde oxidase	enzyme
Mercaptopurine	Amidophosphoribosyltransferase	target
Mercaptopurine	Inosine-5'-monophosphate dehydrogenase	target
Melphalan	DNA	target
Melphalan	Solute carrier family 22 member 3	transporter
Melphalan	Large neutral amino acids transporter small subunit 1	transporter
Fludarabine	DNA polymerase alpha catalytic subunit	target
Fludarabine	Ribonucleoside-diphosphate reductase large subunit	target
Fludarabine	Equilibrative nucleoside transporter 1	transporter
Fludarabine	DNA	target
Fludarabine	Deoxycytidine kinase	target
Fludarabine	Solute carrier family 28 member 3	transporter
Capecitabine	Thymidylate synthase	target
Capecitabine	Thymidine phosphorylase	enzyme
Capecitabine	Cytidine deaminase	enzyme
Capecitabine	Liver carboxylesterase 1	enzyme
Capecitabine	Cytochrome P450 2C9	enzyme
Capecitabine	DNA	target
Capecitabine	RNA	target
Capecitabine	Serum albumin	carrier
Capecitabine	Uridine phosphorylase 1	enzyme
Capecitabine	Uridine phosphorylase 2	enzyme
Procarbazine	DNA	target
Procarbazine	Xanthine dehydrogenase/oxidase	enzyme
Procarbazine	Monoamine oxidase	target
Arsenic trioxide	Inhibitor of nuclear factor kappa-B kinase subunit beta	target
Arsenic trioxide	Transcription factor AP-1	target
Arsenic trioxide	G1/S-specific cyclin-D1	target
Arsenic trioxide	Mitogen-activated protein kinase 3	target
Arsenic trioxide	Mitogen-activated protein kinase 1	target
Arsenic trioxide	RAC-alpha serine/threonine-protein kinase	target
Arsenic trioxide	Canalicular multispecific organic anion transporter 1	transporter
Arsenic trioxide	Thioredoxin reductase 1, cytoplasmic	target
Arsenic trioxide	P-glycoprotein 1	transporter
Arsenic trioxide	Cytochrome P450 3A4	enzyme
Arsenic trioxide	Cyclin-dependent kinase inhibitor 1	target
Arsenic trioxide	Histone deacetylase 1	target
Arsenic trioxide	Protein PML	target
Arsenic trioxide	Serum albumin	carrier
Idarubicin	DNA topoisomerase 2-alpha	target
Idarubicin	DNA	target
Idarubicin	Multidrug resistance-associated protein 1	transporter
Idarubicin	Cytochrome P450 2C9	enzyme
Idarubicin	Cytochrome P450 2D6	enzyme
Ifosfamide	Cytochrome P450 2B6	enzyme
Ifosfamide	DNA	target
Ifosfamide	Cytochrome P450 3A4	enzyme
Ifosfamide	Cytochrome P450 3A5	enzyme
Ifosfamide	Cytochrome P450 2C9	enzyme
Ifosfamide	Cytochrome P450 2C8	enzyme
Ifosfamide	Cytochrome P450 2A6	enzyme
Ifosfamide	Cytochrome P450 2C19	enzyme
Ifosfamide	Cytochrome P450 2C18	enzyme
Ifosfamide	Prostaglandin G/H synthase 1	enzyme
Ifosfamide	Nuclear receptor subfamily 1 group I member 2	target
Estramustine	Estrogen receptor beta	target
Estramustine	Estrogen receptor alpha	target
Estramustine	Microtubule-associated protein 2	target
Estramustine	Microtubule-associated protein 1A	target
Estramustine	P-glycoprotein 1	transporter
Estramustine	Cytochrome P450 3A4	enzyme
Mitoxantrone	DNA topoisomerase 2-alpha	target
Mitoxantrone	Cytochrome P450 2E1	enzyme
Mitoxantrone	P-glycoprotein 1	transporter
Mitoxantrone	Multidrug resistance-associated protein 1	transporter
Mitoxantrone	ATP-binding cassette sub-family G member 2	transporter
Mitoxantrone	DNA	target
Mitoxantrone	Cytochrome P450 1B1	enzyme
Mitoxantrone	Cytochrome P450 3A4	enzyme
Lomustine	DNA	target
Lomustine	Cytochrome P450 3A4	enzyme
Lomustine	Cytochrome P450 2D6	enzyme
Lomustine	Stathmin-4	target
Paclitaxel	Apoptosis regulator Bcl-2	target
Paclitaxel	Tubulin beta-1 chain	target
Paclitaxel	Cytochrome P450 2C8	enzyme
Paclitaxel	Cytochrome P450 3A4	enzyme
Paclitaxel	Cytochrome P450 3A5	enzyme
Paclitaxel	Cytochrome P450 3A7	enzyme
Paclitaxel	Bile salt export pump	transporter
Paclitaxel	P-glycoprotein 1	transporter
Paclitaxel	Multidrug resistance-associated protein 1	transporter
Paclitaxel	Multidrug resistance-associated protein 7	transporter
Paclitaxel	Cytochrome P450 19A1	enzyme
Paclitaxel	Cytochrome P450 1B1	enzyme
Paclitaxel	Solute carrier organic anion transporter family member 1B3	transporter
Paclitaxel	Nuclear receptor subfamily 1 group I member 2	target
Paclitaxel	Microtubule-associated protein 4	target
Paclitaxel	Microtubule-associated protein 2	target
Paclitaxel	Microtubule-associated protein tau	target
Paclitaxel	Canalicular multispecific organic anion transporter 1	transporter
Docetaxel	Apoptosis regulator Bcl-2	target
Docetaxel	Tubulin beta-1 chain	target
Docetaxel	Cytochrome P450 3A4	enzyme
Docetaxel	Cytochrome P450 3A5	enzyme
Docetaxel	Cytochrome P450 3A7	enzyme
Docetaxel	P-glycoprotein 1	transporter
Docetaxel	Multidrug resistance-associated protein 7	transporter
Docetaxel	Cytochrome P450 1B1	enzyme
Docetaxel	Microtubule-associated protein 2	target
Docetaxel	Microtubule-associated protein 4	target
Docetaxel	Microtubule-associated protein tau	target
Docetaxel	Solute carrier organic anion transporter family member 1B3	transporter
Docetaxel	Solute carrier family 22 member 7	transporter
Docetaxel	ATP-binding cassette sub-family G member 2	transporter
Docetaxel	Canalicular multispecific organic anion transporter 1	transporter
Docetaxel	Multidrug resistance-associated protein 1	transporter
Docetaxel	Nuclear receptor subfamily 1 group I member 2	target
Dasatinib	Tyrosine-protein kinase ABL1	target
Dasatinib	Abelson tyrosine-protein kinase 2	target
Dasatinib	Proto-oncogene tyrosine-protein kinase Src	target
Dasatinib	Tyrosine-protein kinase Fyn	target
Dasatinib	Tyrosine-protein kinase Lck	target
Dasatinib	Tyrosine-protein kinase Yes	target
Dasatinib	Mast/stem cell growth factor receptor Kit	target
Dasatinib	Platelet-derived growth factor receptor beta	target
Dasatinib	Ephrin type-A receptor 2	target
Dasatinib	Signal transducer and activator of transcription 5B	target
Dasatinib	Cytochrome P450 3A4	enzyme
Dasatinib	P-glycoprotein 1	transporter
Dasatinib	ATP-binding cassette sub-family G member 2	transporter
Dasatinib	Cytochrome P450 1A1	enzyme
Dasatinib	Cytochrome P450 1A2	enzyme
Dasatinib	Cytochrome P450 1B1	enzyme
Dasatinib	Cytochrome P450 3A5	enzyme
Dasatinib	Dimethylaniline monooxygenase [N-oxide-forming] 3	enzyme
Dasatinib	Tyrosine-protein kinase BTK	target
Dasatinib	Nuclear receptor subfamily 4 group A member 3	target
Dasatinib	Breakpoint cluster region protein	target
Dasatinib	Tyrosine-protein kinase CSK	target
Dasatinib	Ephrin type-A receptor 5	target
Dasatinib	Ephrin type-B receptor 4	target
Dasatinib	Tyrosine-protein kinase Fgr	target
Dasatinib	Tyrosine-protein kinase FRK	target
Dasatinib	Heat shock cognate 71 kDa protein	target
Dasatinib	Tyrosine-protein kinase Lyn	target
Dasatinib	Mitogen-activated protein kinase kinase kinase MLT	target
Dasatinib	Mitogen-activated protein kinase 14	target
Dasatinib	Amidophosphoribosyltransferase	target
Lapatinib	Epidermal growth factor receptor	target
Lapatinib	Receptor tyrosine-protein kinase erbB-2	target
Lapatinib	Cytochrome P450 3A4	enzyme
Lapatinib	Cytochrome P450 2C8	enzyme
Lapatinib	P-glycoprotein 1	transporter
Lapatinib	Antigen peptide transporter 1	transporter
Lapatinib	Cytochrome P450 3A5	enzyme
Lapatinib	Cytochrome P450 2C19	enzyme
Decitabine	DNA	target
Decitabine	DNA (cytosine-5)-methyltransferase 1	target
Decitabine	Deoxycytidine kinase	enzyme
Decitabine	UMP-CMP kinase	enzyme
Decitabine	Nucleoside diphosphokinase	enzyme
Decitabine	Cytidine deaminase	enzyme
Decitabine	DNA (cytosine-5)-methyltransferase 3A	target
Decitabine	DNA (cytosine-5)-methyltransferase 3B	target
Decitabine	Sodium/nucleoside cotransporter 1	transporter
Decitabine	Histone deacetylase	target
Sunitinib	Platelet-derived growth factor receptor beta	target
Sunitinib	Vascular endothelial growth factor receptor 1	target
Sunitinib	Vascular endothelial growth factor receptor 2	target
Sunitinib	Vascular endothelial growth factor receptor 3	target
Sunitinib	Mast/stem cell growth factor receptor Kit	target
Sunitinib	Receptor-type tyrosine-protein kinase FLT3	target
Sunitinib	Macrophage colony-stimulating factor 1 receptor	target
Sunitinib	Platelet-derived growth factor receptor alpha	target
Sunitinib	Cytochrome P450 3A4	enzyme
Sunitinib	Cytochrome P450 3A5	enzyme
Sunitinib	Cytochrome P450 3A7	enzyme
Sunitinib	Multidrug resistance-associated protein 4	transporter
Sunitinib	P-glycoprotein 1	transporter
Sunitinib	Canalicular multispecific organic anion transporter 1	transporter
Sunitinib	ATP-binding cassette sub-family G member 2	transporter
Sunitinib	Hepatocyte growth factor receptor	target
Panitumumab	Epidermal growth factor receptor	target
Vorinostat	Histone deacetylase 1	target
Vorinostat	Histone deacetylase 2	target
Vorinostat	Histone deacetylase 3	target
Vorinostat	Histone deacetylase 6	target
Vorinostat	Histone deacetylase 8	target
Vorinostat	Acetoin utilization protein	target
Vorinostat	Histone deacetylase	target
Fotemustine	Thioredoxin reductase 1, cytoplasmic	target
Thiotepa	Cytochrome P450 2B6	enzyme
Thiotepa	Cytochrome P450 3A4	enzyme
Thiotepa	DNA	target
Thiotepa	Cholinesterase	enzyme
Omacetaxine mepesuccinate	50S ribosomal protein L2	target
Omacetaxine mepesuccinate	60S ribosomal protein L3	target
Satraplatin	DNA	target
Belinostat	Histone deacetylase	target
Belinostat	Cytochrome P450 1A2	enzyme
Belinostat	UDP-glucuronosyltransferase 1-1	enzyme
Belinostat	Cytochrome P450 2C8	enzyme
Belinostat	Cytochrome P450 2C9	enzyme
Belinostat	P-glycoprotein 1	transporter
Belinostat	Cytochrome P450 3A4	enzyme
Trabectedin	Cytochrome P450 3A4	enzyme
Trabectedin	Cytochrome P450 2C9	enzyme
Trabectedin	Cytochrome P450 2D6	enzyme
Trabectedin	Cytochrome P450 2E1	enzyme
Trabectedin	Cytochrome P450 2C19	enzyme
Trabectedin	DNA	target
Trabectedin	Prostaglandin G/H synthase 1	enzyme
Ramucirumab	Vascular endothelial growth factor receptor 2	target
Trastuzumab emtansine	Receptor tyrosine-protein kinase erbB-2	target
Trastuzumab emtansine	P-glycoprotein 1	transporter
Trastuzumab emtansine	Cytochrome P450 3A4	enzyme
Trastuzumab emtansine	Cytochrome P450 3A5	enzyme
Romidepsin	Cytochrome P450 3A4	enzyme
Romidepsin	Cytochrome P450 3A5	enzyme
Romidepsin	P-glycoprotein 1	transporter
Romidepsin	Solute carrier organic anion transporter family member 1B3	transporter
Romidepsin	Cytochrome P450 1A1	enzyme
Romidepsin	Cytochrome P450 2B6	enzyme
Romidepsin	Cytochrome P450 2C19	enzyme
Romidepsin	Histone deacetylase 1	target
Romidepsin	Histone deacetylase 2	target
Romidepsin	Histone deacetylase 4	target
Romidepsin	Histone deacetylase 6	target
Romidepsin	Multidrug resistance-associated protein 1	target
Romidepsin	Bile salt export pump	transporter
Romidepsin	Solute carrier organic anion transporter family member 1B1	transporter
Romidepsin	Solute carrier family 22 member 6	transporter
Romidepsin	Solute carrier family 22 member 2	transporter
Romidepsin	Histone deacetylase	target
Amrubicin	DNA topoisomerase 2-alpha	target
Amrubicin	DNA	target
Amrubicin	NADPH--cytochrome P450 reductase	enzyme
Amrubicin	Carbonyl reductase [NADPH] 1	enzyme
Amrubicin	ATP-binding cassette sub-family B member 5	transporter
Lonidamine	Cystic fibrosis transmembrane conductance regulator	target
Lonidamine	Hexokinase-1	target
Temsirolimus	Serine/threonine-protein kinase mTOR	target
Temsirolimus	Cytochrome P450 3A4	enzyme
Temsirolimus	Cytochrome P450 3A5	enzyme
Temsirolimus	Cytochrome P450 3A7	enzyme
Temsirolimus	Cytochrome P450 2D6	enzyme
Temsirolimus	P-glycoprotein 1	transporter
Pertuzumab	Receptor tyrosine-protein kinase erbB-2	target
Panobinostat	Cytochrome P450 2D6	enzyme
Panobinostat	Cytochrome P450 3A4	enzyme
Panobinostat	P-glycoprotein 1	transporter
Panobinostat	Histone deacetylase	target
Bendamustine	Cytochrome P450 1A2	enzyme
Plicamycin	DNA	target
Ponatinib	Tyrosine-protein kinase ABL1	target
Ponatinib	Breakpoint cluster region protein	target
Ponatinib	Mast/stem cell growth factor receptor Kit	target
Ponatinib	Proto-oncogene tyrosine-protein kinase receptor Ret	target
Ponatinib	Angiopoietin-1 receptor	target
Ponatinib	Receptor-type tyrosine-protein kinase FLT3	target
Ponatinib	Cytochrome P450 3A4	enzyme
Ponatinib	Cytochrome P450 2C8	enzyme
Ponatinib	Cytochrome P450 2D6	enzyme
Ponatinib	Cytochrome P450 3A5	enzyme
Ponatinib	P-glycoprotein 1	transporter
Ponatinib	ATP-binding cassette sub-family G member 2	transporter
Ponatinib	Fibroblast growth factor receptor 1	target
Ponatinib	Fibroblast growth factor receptor 2	target
Ponatinib	Fibroblast growth factor receptor 3	target
Ponatinib	Fibroblast growth factor receptor 4	target
Ponatinib	Tyrosine-protein kinase Lck	target
Ponatinib	Proto-oncogene tyrosine-protein kinase Src	target
Ponatinib	Tyrosine-protein kinase Lyn	target
Ponatinib	Vascular endothelial growth factor receptor 2	target
Ponatinib	Platelet-derived growth factor receptor alpha	target
Trametinib	Cytochrome P450 2C8	enzyme
Trametinib	Cytochrome P450 3A4	enzyme
Trametinib	Dual specificity mitogen-activated protein kinase kinase 1	target
Trametinib	Dual specificity mitogen-activated protein kinase kinase 2	target
Dabrafenib	Cytochrome P450 3A4	enzyme
Dabrafenib	Cytochrome P450 2C8	enzyme
Dabrafenib	P-glycoprotein 1	transporter
Dabrafenib	ATP-binding cassette sub-family G member 2	transporter
Dabrafenib	Solute carrier organic anion transporter family member 1B1	transporter
Dabrafenib	Solute carrier organic anion transporter family member 1B3	transporter
Dabrafenib	Solute carrier family 22 member 6	transporter
Dabrafenib	Solute carrier family 22 member 8	transporter
Dabrafenib	Serine/threonine-protein kinase B-raf	target
Dabrafenib	RAF proto-oncogene serine/threonine-protein kinase	target
Dabrafenib	Serine/threonine-protein kinase SIK1	target
Dabrafenib	Serine/threonine-protein kinase Nek11	target
Dabrafenib	LIM domain kinase 1	target
Dabrafenib	Cytochrome P450 2B6	enzyme
Dabrafenib	Cytochrome P450 2C9	enzyme
Dabrafenib	Cytochrome P450 2C19	enzyme
Dabrafenib	Cytochrome P450 1A2	enzyme
Dabrafenib	Serum albumin	carrier
Dabrafenib	Solute carrier organic anion transporter family member 1A2	transporter
Dabrafenib	Solute carrier family 22 member 2	transporter
Dabrafenib	UDP-glucuronosyltransferase 1-1	enzyme
Obinutuzumab	B-lymphocyte antigen CD20	target
Miltefosine	Phospholipase D1	enzyme
Miltefosine	P-glycoprotein 1	target
Nivolumab	Programmed cell death protein 1	target
Nivolumab	Programmed cell death 1 ligand 1	target
Pembrolizumab	Programmed cell death protein 1	target
Pembrolizumab	Programmed cell death 1 ligand 1	target
Blinatumomab	B-lymphocyte antigen CD19	target
Blinatumomab	T-cell surface glycoprotein CD3 delta chain	target
Idelalisib	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform	target
Idelalisib	ATP-binding cassette sub-family G member 2	transporter
Idelalisib	P-glycoprotein 1	transporter
Idelalisib	Aldehyde oxidase	enzyme
Idelalisib	Cytochrome P450 2C8	enzyme
Idelalisib	Cytochrome P450 2C19	enzyme
Idelalisib	Cytochrome P450 2B6	enzyme
Idelalisib	Cytochrome P450 3A4	enzyme
Idelalisib	Solute carrier organic anion transporter family member 1B1	transporter
Idelalisib	Solute carrier organic anion transporter family member 1B3	transporter
Idelalisib	Cytochrome P450 3A5	enzyme
Idelalisib	Cytochrome P450 3A43	enzyme
Idelalisib	Cytochrome P450 3A7	enzyme
Idelalisib	UDP-glucuronosyltransferase 1-4	enzyme
Ceritinib	ALK tyrosine kinase receptor	target
Ceritinib	P-glycoprotein 1	transporter
Ceritinib	Cytochrome P450 2C9	enzyme
Ceritinib	Cytochrome P450 3A4	enzyme
Palbociclib	Cyclin-dependent kinase 4	target
Palbociclib	Cyclin-dependent kinase 6	target
Palbociclib	Cytochrome P450 3A4	enzyme
Palbociclib	Bile salt sulfotransferase	enzyme
Palbociclib	P-glycoprotein 1	transporter
Palbociclib	ATP-binding cassette sub-family G member 2	transporter
Palbociclib	Serum albumin	carrier
Palbociclib	Solute carrier family 22 member 1	transporter
Olaparib	Poly [ADP-ribose] polymerase 1	target
Olaparib	Cytochrome P450 3A4	enzyme
Olaparib	Cytochrome P450 2B6	enzyme
Olaparib	Poly [ADP-ribose] polymerase 2	target
Olaparib	Poly [ADP-ribose] polymerase 3	target
Olaparib	Cytochrome P450 3A5	enzyme
Olaparib	P-glycoprotein 1	transporter
Olaparib	ATP-binding cassette sub-family G member 2	transporter
Olaparib	Aldo-keto reductase family 1 member C3	target
Olaparib	UDP-glucuronosyltransferase 1-1	enzyme
Olaparib	Serum albumin	carrier
Olaparib	Alpha-1-acid glycoprotein 1	carrier
Lenvatinib	Vascular endothelial growth factor receptor 1	target
Lenvatinib	Vascular endothelial growth factor receptor 2	target
Lenvatinib	Vascular endothelial growth factor receptor 3	target
Lenvatinib	Fibroblast growth factor receptor 1	target
Lenvatinib	Fibroblast growth factor receptor 2	target
Lenvatinib	Fibroblast growth factor receptor 3	target
Lenvatinib	Fibroblast growth factor receptor 4	target
Lenvatinib	Platelet-derived growth factor receptor alpha	target
Lenvatinib	Proto-oncogene tyrosine-protein kinase receptor Ret	target
Lenvatinib	Mast/stem cell growth factor receptor Kit	target
Lenvatinib	P-glycoprotein 1	transporter
Lenvatinib	ATP-binding cassette sub-family G member 2	transporter
Lenvatinib	Cytochrome P450 3A4	enzyme
Lenvatinib	Aldehyde oxidase	enzyme
Lenvatinib	Cytochrome P450 2C8	enzyme
Lenvatinib	Cytochrome P450 2C9	enzyme
Lenvatinib	Cytochrome P450 1A2	enzyme
Lenvatinib	Cytochrome P450 2B6	enzyme
Lenvatinib	Cytochrome P450 2C19	enzyme
Lenvatinib	Solute carrier family 22 member 6	transporter
Lenvatinib	Solute carrier family 22 member 8	transporter
Lenvatinib	Solute carrier family 22 member 2	transporter
Lenvatinib	Solute carrier organic anion transporter family member 1B1	transporter
Lenvatinib	Bile salt export pump	transporter
Lenvatinib	Cytochrome P450 2D6	enzyme
Lenvatinib	Solute carrier organic anion transporter family member 1B3	transporter
Nintedanib	Vascular endothelial growth factor receptor 1	target
Nintedanib	Vascular endothelial growth factor receptor 2	target
Nintedanib	Vascular endothelial growth factor receptor 3	target
Nintedanib	Platelet-derived growth factor receptor alpha	target
Nintedanib	Platelet-derived growth factor receptor beta	target
Nintedanib	Fibroblast growth factor receptor 1	target
Nintedanib	Fibroblast growth factor receptor 2	target
Nintedanib	Fibroblast growth factor receptor 3	target
Nintedanib	Receptor-type tyrosine-protein kinase FLT3	target
Nintedanib	Tyrosine-protein kinase Lck	target
Nintedanib	Tyrosine-protein kinase Lyn	target
Nintedanib	Proto-oncogene tyrosine-protein kinase Src	target
Nintedanib	P-glycoprotein 1	transporter
Nintedanib	Cytochrome P450 3A4	enzyme
Nintedanib	Solute carrier family 22 member 1	transporter
Nintedanib	Serum albumin	carrier
Nintedanib	UDP-glucuronosyltransferase 1-1	enzyme
Nintedanib	UDP-glucuronosyltransferase 1-7	enzyme
Nintedanib	UDP-glucuronosyltransferase 1-8	enzyme
Nintedanib	UDP-glucuronosyltransferase 1-10	enzyme
Nintedanib	ATP-binding cassette sub-family G member 2	transporter
Tegafur	Cytochrome P450 2A6	enzyme
Tegafur	Thymidylate synthase	target
Tegafur	Cytochrome P450 1A2	enzyme
Tegafur	Cytochrome P450 2C8	enzyme
Tegafur	Cytochrome P450 2E1	enzyme
Tegafur	Cytochrome P450 3A5	enzyme
Tegafur	Thyroxine-binding globulin	carrier
Ixazomib	Cytochrome P450 3A4	enzyme
Ixazomib	Cytochrome P450 1A2	enzyme
Ixazomib	Cytochrome P450 2B6	enzyme
Ixazomib	Cytochrome P450 2C8	enzyme
Ixazomib	Cytochrome P450 2D6	enzyme
Ixazomib	Cytochrome P450 2C19	enzyme
Ixazomib	Cytochrome P450 2C9	enzyme
Cediranib	Vascular endothelial growth factor receptor 2	target
Gemtuzumab ozogamicin	Myeloid cell surface antigen CD33	target
Gemtuzumab ozogamicin	Low affinity immunoglobulin gamma Fc region receptor III-B	target
Gemtuzumab ozogamicin	Low affinity immunoglobulin gamma Fc region receptor III-A	target
Gemtuzumab ozogamicin	High affinity immunoglobulin gamma Fc receptor I	target
Leuprolide	Gonadotropin-releasing hormone receptor	target
Aldesleukin	Interleukin-2 receptor subunit beta	target
Aldesleukin	Interleukin-2 receptor subunit alpha	target
Aldesleukin	Cytokine receptor common subunit gamma	target
Aldesleukin	Prostaglandin G/H synthase 2	enzyme
Aldesleukin	Cytosolic phospholipase A2	enzyme
Aldesleukin	Cytochrome P450 3A4	enzyme
Aldesleukin	Xanthine dehydrogenase/oxidase	enzyme
Aldesleukin	Cytochrome P450 2E1	enzyme
Alemtuzumab	CAMPATH-1 antigen	target
Alemtuzumab	Low affinity immunoglobulin gamma Fc region receptor III-B	target
Alemtuzumab	Low affinity immunoglobulin gamma Fc region receptor III-A	target
Alemtuzumab	High affinity immunoglobulin gamma Fc receptor I	target
Alemtuzumab	Low affinity immunoglobulin gamma Fc region receptor II-a	target
Alemtuzumab	Low affinity immunoglobulin gamma Fc region receptor II-b	target
Alemtuzumab	Low affinity immunoglobulin gamma Fc region receptor II-c	target
Megestrol acetate	Progesterone receptor	target
Megestrol acetate	Glucocorticoid receptor	target
Megestrol acetate	P-glycoprotein 1	transporter
Megestrol acetate	Cytochrome P450 3A4	enzyme
Lenalidomide	Prostaglandin G/H synthase 2	target
Lenalidomide	Tumor necrosis factor ligand superfamily member 11	target
Lenalidomide	Cadherin-5	target
Lenalidomide	Protein cereblon	target
Lenalidomide	P-glycoprotein 1	transporter
Flutamide	Androgen receptor	target
Flutamide	Cytochrome P450 1A2	enzyme
Flutamide	Cytochrome P450 3A4	enzyme
Flutamide	Cytochrome P450 1A1	enzyme
Flutamide	Cytochrome P450 1B1	enzyme
Flutamide	Cytochrome P450 3A5	enzyme
Flutamide	Aryl hydrocarbon receptor	target
Flutamide	Nuclear receptor subfamily 1 group I member 2	target
Flutamide	Multidrug resistance-associated protein 1	transporter
Nilutamide	Androgen receptor	target
Nilutamide	Cytochrome P450 2C19	enzyme
Nilutamide	NADPH--cytochrome P450 reductase	enzyme
Tamoxifen	Estrogen receptor alpha	target
Tamoxifen	Estrogen receptor beta	target
Tamoxifen	Cytochrome P450 2C9	enzyme
Tamoxifen	Cytochrome P450 3A4	enzyme
Tamoxifen	Cytochrome P450 2D6	enzyme
Tamoxifen	Cytochrome P450 2C8	enzyme
Tamoxifen	Cytochrome P450 2B6	enzyme
Tamoxifen	Liver carboxylesterase 1	enzyme
Tamoxifen	Cytochrome P450 3A5	enzyme
Tamoxifen	Cytochrome P450 1A1	enzyme
Tamoxifen	Cytochrome P450 1B1	enzyme
Tamoxifen	Cytochrome P450 2C19	enzyme
Tamoxifen	Dimethylaniline monooxygenase [N-oxide-forming] 1	enzyme
Tamoxifen	Dimethylaniline monooxygenase [N-oxide-forming] 3	enzyme
Tamoxifen	Cytochrome P450 3A7	enzyme
Tamoxifen	P-glycoprotein 1	transporter
Tamoxifen	ATP-binding cassette sub-family G member 2	transporter
Tamoxifen	Cytochrome P450 19A1	enzyme
Tamoxifen	Cytochrome P450 2A6	enzyme
Tamoxifen	Cytochrome P450 2E1	enzyme
Tamoxifen	UDP-glucuronosyltransferase 1-10	enzyme
Tamoxifen	Sulfotransferase 1A1	enzyme
Tamoxifen	Canalicular multispecific organic anion transporter 1	transporter
Tamoxifen	3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase	target
Tamoxifen	Protein kinase C	target
Tamoxifen	Androgen receptor	target
Tamoxifen	Potassium voltage-gated channel subfamily H member 2	target
Tamoxifen	Nuclear receptor subfamily 1 group I member 2	target
Tamoxifen	Estrogen-related receptor gamma	target
Tamoxifen	Sex hormone-binding globulin	target
Tamoxifen	Bile salt export pump	transporter
Tamoxifen	Thyroxine-binding globulin	carrier
Tamoxifen	Bile salt sulfotransferase	enzyme
Tamoxifen	Cytochrome P450 1A2	enzyme
Tamoxifen	UDP-glucuronosyltransferase 2B7	enzyme
Tamoxifen	UDP-glucuronosyltransferase 2B17	enzyme
Tamoxifen	Estrogen sulfotransferase	enzyme
Tamoxifen	ATP-binding cassette sub-family A member 1	transporter
Tamoxifen	Mitogen-activated protein kinase 8	target
Tamoxifen	Serum albumin	carrier
Fulvestrant	Estrogen receptor alpha	target
Fulvestrant	Cytochrome P450 3A4	enzyme
Fulvestrant	UDP-glucuronosyltransferase 1-1	enzyme
Exemestane	Cytochrome P450 19A1	target
Exemestane	Cytochrome P450 3A4	enzyme
Exemestane	Cytochrome P450 19A1	enzyme
Letrozole	Cytochrome P450 19A1	target
Letrozole	Cytochrome P450 3A4	enzyme
Letrozole	Cytochrome P450 2A6	enzyme
Letrozole	Cytochrome P450 19A1	enzyme
Letrozole	Cytochrome P450 2C19	enzyme
Letrozole	UDP-glucuronosyltransferase 2B7	enzyme
Letrozole	Serum albumin	carrier
Letrozole	P-glycoprotein 1	transporter
Bicalutamide	Androgen receptor	target
Bicalutamide	Cytochrome P450 3A4	enzyme
Bicalutamide	Cytochrome P450 2C19	enzyme
Bicalutamide	Cytochrome P450 2C9	enzyme
Bicalutamide	Cytochrome P450 2D6	enzyme
Bicalutamide	P-glycoprotein 1	transporter
Anastrozole	Cytochrome P450 19A1	target
Anastrozole	P-glycoprotein 1	transporter
Anastrozole	Cytochrome P450 3A4	enzyme
Anastrozole	Cytochrome P450 3A5	enzyme
Anastrozole	Cytochrome P450 2C8	enzyme
Anastrozole	UDP-glucuronosyltransferase 1-4	enzyme
Anastrozole	UDP-glucuronosyltransferase 1-3	enzyme
Anastrozole	UDP-glucuronosyltransferase 2B7	enzyme
Anastrozole	Cytochrome P450 1A2	enzyme
Anastrozole	Cytochrome P450 2C9	enzyme
Everolimus	Serine/threonine-protein kinase mTOR	target
Everolimus	Cytochrome P450 3A4	enzyme
Everolimus	Solute carrier organic anion transporter family member 1B1	transporter
Everolimus	Solute carrier organic anion transporter family member 1B3	transporter
Everolimus	Solute carrier organic anion transporter family member 1A2	transporter
Everolimus	Cytochrome P450 2D6	enzyme
Everolimus	P-glycoprotein 1	transporter
Nelarabine	DNA	target
Nelarabine	Adenosine deaminase	enzyme
Nelarabine	Deoxycytidine kinase	enzyme
Nelarabine	Deoxyguanosine kinase, mitochondrial	enzyme
Nelarabine	DNA polymerase alpha catalytic subunit	target
Nilotinib	Tyrosine-protein kinase ABL1	target
Nilotinib	Mast/stem cell growth factor receptor Kit	target
Nilotinib	Cytochrome P450 2D6	enzyme
Nilotinib	Cytochrome P450 2C8	enzyme
Nilotinib	Cytochrome P450 2C9	enzyme
Nilotinib	Cytochrome P450 3A4	enzyme
Nilotinib	P-glycoprotein 1	transporter
Nilotinib	ATP-binding cassette sub-family G member 2	transporter
Nilotinib	UDP-glucuronosyltransferase 1-1	transporter
Nilotinib	Cytochrome P450 2B6	enzyme
Nilotinib	Solute carrier organic anion transporter family member 1B1	transporter
Vandetanib	Vascular endothelial growth factor A	target
Vandetanib	Epidermal growth factor receptor	target
Vandetanib	Multidrug resistance-associated protein 1	transporter
Vandetanib	ATP-binding cassette sub-family G member 2	transporter
Vandetanib	Proto-oncogene tyrosine-protein kinase receptor Ret	target
Vandetanib	Dimethylaniline monooxygenase [N-oxide-forming] 1	enzyme
Vandetanib	Dimethylaniline monooxygenase [N-oxide-forming] 3	enzyme
Vandetanib	Protein-tyrosine kinase 6	target
Vandetanib	Angiopoietin-1 receptor	target
Vandetanib	Alpha-1-acid glycoprotein 1	carrier
Vandetanib	Serum albumin	carrier
Vandetanib	Cytochrome P450 3A4	enzyme
Vandetanib	Solute carrier family 22 member 2	transporter
Vandetanib	P-glycoprotein 1	transporter
Ipilimumab	Cytotoxic T-lymphocyte protein 4	target
Pazopanib	Vascular endothelial growth factor receptor 1	target
Pazopanib	Vascular endothelial growth factor receptor 2	target
Pazopanib	Vascular endothelial growth factor receptor 3	target
Pazopanib	Platelet-derived growth factor receptor alpha	target
Pazopanib	Platelet-derived growth factor receptor beta	target
Pazopanib	Mast/stem cell growth factor receptor Kit	target
Pazopanib	Cytochrome P450 3A4	enzyme
Pazopanib	Cytochrome P450 2D6	enzyme
Pazopanib	Cytochrome P450 2C8	enzyme
Pazopanib	Cytochrome P450 1A2	enzyme
Pazopanib	P-glycoprotein 1	transporter
Pazopanib	ATP-binding cassette sub-family G member 2	transporter
Pazopanib	Solute carrier organic anion transporter family member 1B1	transporter
Pazopanib	UDP-glucuronosyltransferase 1-1	transporter
Pazopanib	Fibroblast growth factor receptor 3	target
Pazopanib	Tyrosine-protein kinase ITK/TSK	target
Pazopanib	Fibroblast growth factor 1	target
Pazopanib	SH2B adapter protein 3	target
Catumaxomab	Epithelial cell adhesion molecule	target
Catumaxomab	Low affinity immunoglobulin gamma Fc region receptor II-a	target
Catumaxomab	Low affinity immunoglobulin gamma Fc region receptor III-A	target
Catumaxomab	Low affinity immunoglobulin gamma Fc region receptor III-B	target
Catumaxomab	T-cell surface glycoprotein CD3 epsilon chain	target
Catumaxomab	High affinity immunoglobulin gamma Fc receptor I	target
Bosutinib	Breakpoint cluster region protein	target
Bosutinib	Tyrosine-protein kinase ABL1	target
Bosutinib	Tyrosine-protein kinase Lyn	target
Bosutinib	Tyrosine-protein kinase HCK	target
Bosutinib	Proto-oncogene tyrosine-protein kinase Src	target
Bosutinib	P-glycoprotein 1	transporter
Bosutinib	Cytochrome P450 3A4	enzyme
Bosutinib	Cyclin-dependent kinase 2	target
Bosutinib	Dual specificity mitogen-activated protein kinase kinase 1	target
Bosutinib	Dual specificity mitogen-activated protein kinase kinase 2	target
Bosutinib	Mitogen-activated protein kinase kinase kinase 2	target
Bosutinib	Calcium/calmodulin-dependent protein kinase type II subunit gamma	target
Bosutinib	Cytochrome P450 2C8	enzyme
Axitinib	Vascular endothelial growth factor receptor 1	target
Axitinib	Vascular endothelial growth factor receptor 2	target
Axitinib	Vascular endothelial growth factor receptor 3	target
Axitinib	Cytochrome P450 3A4	enzyme
Axitinib	Cytochrome P450 3A5	enzyme
Axitinib	Cytochrome P450 1A2	enzyme
Axitinib	Cytochrome P450 2C19	enzyme
Axitinib	UDP-glucuronosyltransferase 1-1	enzyme
Axitinib	P-glycoprotein 1	transporter
Axitinib	Solute carrier organic anion transporter family member 1B1	transporter
Ofatumumab	B-lymphocyte antigen CD20	target
Cabazitaxel	Cytochrome P450 3A4	enzyme
Cabazitaxel	Cytochrome P450 3A5	enzyme
Cabazitaxel	Cytochrome P450 2C8	enzyme
Cabazitaxel	P-glycoprotein 1	transporter
Cabazitaxel	ATP-binding cassette sub-family G member 2	transporter
Cabazitaxel	Tubulin alpha-4A chain	target
Cabazitaxel	Tubulin beta-1 chain	target
Cabazitaxel	Solute carrier organic anion transporter family member 1B1	transporter
Cabazitaxel	Solute carrier organic anion transporter family member 1B3	transporter
Vismodegib	Smoothened homolog	target
Vismodegib	Cytochrome P450 2C9	enzyme
Vismodegib	Cytochrome P450 3A4	enzyme
Vismodegib	P-glycoprotein 1	transporter
Vismodegib	Cytochrome P450 2C8	enzyme
Vismodegib	Cytochrome P450 2C19	enzyme
Vismodegib	ATP-binding cassette sub-family G member 2	transporter
Vismodegib	Serum albumin	carrier
Vismodegib	Alpha-1-acid glycoprotein 1	carrier
Crizotinib	Cytochrome P450 3A4	enzyme
Crizotinib	Cytochrome P450 3A5	enzyme
Crizotinib	P-glycoprotein 1	transporter
Crizotinib	ALK tyrosine kinase receptor	target
Crizotinib	Hepatocyte growth factor receptor	target
Crizotinib	Cytochrome P450 2B6	enzyme
Crizotinib	Cytochrome P450 3A Subfamily	enzyme
Crizotinib	Serum albumin	carrier
Crizotinib	alpha1-acid glycoprotein	carrier
Crizotinib	Proto-oncogene tyrosine-protein kinase ROS	target
Crizotinib	Macrophage-stimulating protein receptor	target
Brentuximab vedotin	Tumor necrosis factor receptor superfamily member 8	target
Brentuximab vedotin	Cytochrome P450 3A4	enzyme
Brentuximab vedotin	ATP-binding cassette sub-family B member 5	transporter
Eribulin	Apoptosis regulator Bcl-2	target
Eribulin	Tubulin beta-1 chain	target
Ruxolitinib	Tyrosine-protein kinase JAK1	target
Ruxolitinib	Tyrosine-protein kinase JAK2	target
Ruxolitinib	Cytochrome P450 3A4	enzyme
Ruxolitinib	Cytochrome P450 2C9	enzyme
Ruxolitinib	Serum albumin	carrier
Ruxolitinib	Tyrosine-protein kinase JAK3	target
Ruxolitinib	Non-receptor tyrosine-protein kinase TYK2	target
Vemurafenib	Serum albumin	carrier
Vemurafenib	Alpha-1-acid glycoprotein 1	carrier
Vemurafenib	Cytochrome P450 1A2	enzyme
Vemurafenib	Cytochrome P450 2D6	enzyme
Vemurafenib	Cytochrome P450 3A4	enzyme
Vemurafenib	Serine/threonine-protein kinase B-raf	target
Vemurafenib	Multidrug resistance-associated protein 1	transporter
Vemurafenib	ATP-binding cassette sub-family G member 2	transporter
Vemurafenib	Cytochrome P450 2C9	enzyme
Vemurafenib	Cytochrome P450 2C8	enzyme
Vemurafenib	Cytochrome P450 2B6	enzyme
Vemurafenib	P-glycoprotein 1	transporter
Carfilzomib	P-glycoprotein 1	transporter
Carfilzomib	Proteasome subunit beta type-5	target
Carfilzomib	Proteasome subunit beta type-9	target
Carfilzomib	Proteasome subunit beta type-10	target
Carfilzomib	Proteasome subunit beta type-8	target
Carfilzomib	Proteasome subunit beta type-1	target
Carfilzomib	Proteasome subunit beta type-2	target
Regorafenib	Cytochrome P450 3A4	enzyme
Regorafenib	UDP-glucuronosyltransferase 1-9	enzyme
Regorafenib	Proto-oncogene tyrosine-protein kinase receptor Ret	target
Regorafenib	Vascular endothelial growth factor receptor 1	target
Regorafenib	Vascular endothelial growth factor receptor 2	target
Regorafenib	Vascular endothelial growth factor receptor 3	target
Regorafenib	Mast/stem cell growth factor receptor Kit	target
Regorafenib	Platelet-derived growth factor receptor alpha	target
Regorafenib	Platelet-derived growth factor receptor beta	target
Regorafenib	Fibroblast growth factor receptor 1	target
Regorafenib	Fibroblast growth factor receptor 2	target
Regorafenib	Angiopoietin-1 receptor	target
Regorafenib	Discoidin domain-containing receptor 2	target
Regorafenib	High affinity nerve growth factor receptor	target
Regorafenib	Ephrin type-A receptor 2	target
Regorafenib	RAF proto-oncogene serine/threonine-protein kinase	target
Regorafenib	Serine/threonine-protein kinase B-raf	target
Regorafenib	Cytochrome P450 2C8	enzyme
Regorafenib	Cytochrome P450 2C9	enzyme
Regorafenib	Cytochrome P450 2B6	enzyme
Regorafenib	Mitogen-activated protein kinase 11	target
Regorafenib	Tyrosine-protein kinase FRK	target
Regorafenib	Tyrosine-protein kinase ABL1	target
Regorafenib	P-glycoprotein 1	transporter
Regorafenib	ATP-binding cassette sub-family G member 2	transporter
Regorafenib	UDP-glucuronosyltransferase 1-1	enzyme
Regorafenib	Cytochrome P450 2C19	enzyme
Afatinib	Epidermal growth factor receptor	target
Afatinib	Receptor tyrosine-protein kinase erbB-2	target
Afatinib	Receptor tyrosine-protein kinase erbB-4	target
Afatinib	P-glycoprotein 1	transporter
Afatinib	ATP-binding cassette sub-family G member 2	transporter
Ibrutinib	Tyrosine-protein kinase BTK	target
Ibrutinib	Cytochrome P450 3A4	enzyme
Ibrutinib	Cytochrome P450 3A5	enzyme
Ibrutinib	Serum albumin	carrier
Ibrutinib	alpha1-acid glycoprotein	carrier
Ibrutinib	Cytochrome P450 2D6	enzyme
Necitumumab	Epidermal growth factor receptor	target
Abiraterone	Steroid 17-alpha-hydroxylase/17,20 lyase	target
Abiraterone	Serum albumin	carrier
Abiraterone	Alpha-1-acid glycoprotein 1	carrier
Abiraterone	Cytochrome P450 3A4	enzyme
Abiraterone	Bile salt sulfotransferase	enzyme
Abiraterone	Multidrug resistance-associated protein 1	transporter
Abiraterone	Cytochrome P450 2D6	enzyme
Abiraterone	Cytochrome P450 2C8	enzyme
Abiraterone	Cytochrome P450 1A2	enzyme
Abiraterone	Cytochrome P450 2C19	enzyme
Abiraterone	Cytochrome P450 2C9	enzyme
Midostaurin	Protein kinase C alpha type	target
Midostaurin	Vascular endothelial growth factor receptor 2	target
Midostaurin	Mast/stem cell growth factor receptor Kit	target
Midostaurin	Platelet-derived growth factor receptor alpha	target
Midostaurin	Platelet-derived growth factor receptor beta	target
Midostaurin	Receptor-type tyrosine-protein kinase FLT3	target
Midostaurin	Cytochrome P450 3A Subfamily	enzyme
Midostaurin	Cytochrome P450 1A2	enzyme
Midostaurin	Cytochrome P450 2B6	enzyme
Midostaurin	Cytochrome P450 2C8	enzyme
Midostaurin	Cytochrome P450 2C9	enzyme
Midostaurin	Cytochrome P450 2C19	enzyme
Midostaurin	Cytochrome P450 2D6	enzyme
Midostaurin	Cytochrome P450 2E1	enzyme
Midostaurin	Cytochrome P450 3A4	enzyme
Midostaurin	Cytochrome P450 3A5	enzyme
Midostaurin	Cytochrome P450 3A7	enzyme
Midostaurin	Cytochrome P450 3A43	enzyme
Triptorelin	Gonadotropin-releasing hormone receptor	target
Pomalidomide	Cytochrome P450 1A2	enzyme
Pomalidomide	Cytochrome P450 3A4	enzyme
Pomalidomide	P-glycoprotein 1	transporter
Pomalidomide	Protein cereblon	target
Pomalidomide	Tumor necrosis factor	target
Pomalidomide	Prostaglandin G/H synthase 2	target
Osimertinib	Epidermal growth factor receptor	target
Osimertinib	P-glycoprotein 1	transporter
Osimertinib	ATP-binding cassette sub-family G member 2	transporter
Osimertinib	Cytochrome P450 3A4	enzyme
Osimertinib	Cytochrome P450 1A2	enzyme
Daratumumab	ADP-ribosyl cyclase 1	target
Tretinoin	Retinoic acid receptor gamma	target
Tretinoin	Retinoic acid receptor RXR-beta	target
Tretinoin	Retinal dehydrogenase 1	target
Tretinoin	Retinoic acid-induced protein 3	target
Tretinoin	Retinoic acid receptor RXR-gamma	target
Tretinoin	Retinal dehydrogenase 2	target
Tretinoin	Retinoic acid receptor responder protein 1	target
Tretinoin	Cytochrome P450 2C8	enzyme
Tretinoin	Cellular retinoic acid-binding protein 1	transporter
Tretinoin	Cellular retinoic acid-binding protein 2	transporter
Tretinoin	Cytochrome P450 2B6	enzyme
Tretinoin	Cytochrome P450 3A4	enzyme
Tretinoin	Cytochrome P450 3A5	enzyme
Tretinoin	Cytochrome P450 2A6	enzyme
Tretinoin	Cytochrome P450 3A7	enzyme
Tretinoin	Cytochrome P450 2C18	enzyme
Tretinoin	Cytochrome P450 2C9	enzyme
Tretinoin	Cytochrome P450 4A11	enzyme
Tretinoin	Cytochrome P450 1A1	enzyme
Tretinoin	Retinoic acid receptor alpha	target
Tretinoin	Retinoic acid receptor beta	target
Tretinoin	Lipocalin-1	target
Tretinoin	Odorant-binding protein 2a	target
Tretinoin	Retinol-binding protein 4	target
Tretinoin	Serum albumin	carrier
Tretinoin	[Pyruvate dehydrogenase [lipoamide]] kinase isozyme 4, mitochondrial	target
Tretinoin	Retinoic acid receptor RXR-alpha	target
Tretinoin	Cytochrome P450 26A1	target
Tretinoin	Cytochrome P450 26B1	target
Tretinoin	Cytochrome P450 26C1	target
Tretinoin	Hematopoietic prostaglandin D synthase	target
Tretinoin	Carcinoembryonic antigen	target
Goserelin	Lutropin-choriogonadotropic hormone receptor	target
Goserelin	Gonadotropin-releasing hormone receptor	target
Tositumomab	B-lymphocyte antigen CD20	target
Tositumomab	Low affinity immunoglobulin gamma Fc region receptor II-b	target
Octreotide	Myeloperoxidase	enzyme
Octreotide	Cytochrome P450 3A4	enzyme
Octreotide	Somatostatin receptor	target
Octreotide	Serum albumin	carrier
Octreotide	P-glycoprotein 1	transporter
Octreotide	Canalicular multispecific organic anion transporter 1	transporter
Cabergoline	Dopamine D2 receptor	target
Cabergoline	5-hydroxytryptamine receptor 2B	target
Cabergoline	Dopamine D3 receptor	target
Cabergoline	5-hydroxytryptamine receptor 2A	target
Cabergoline	Alpha-2B adrenergic receptor	target
Cabergoline	5-hydroxytryptamine receptor 1D	target
Cabergoline	Dopamine D4 receptor	target
Cabergoline	Alpha-2A adrenergic receptor	target
Cabergoline	5-hydroxytryptamine receptor 1A	target
Cabergoline	Alpha-2C adrenergic receptor	target
Cabergoline	Dopamine D5 receptor	target
Cabergoline	Dopamine D1 receptor	target
Cabergoline	5-hydroxytryptamine receptor 1B	target
Cabergoline	5-hydroxytryptamine receptor 2C	target
Cabergoline	Cytochrome P450 3A4	enzyme
Cabergoline	5-hydroxytryptamine receptor 7	target
Cabergoline	Alpha-1A adrenergic receptor	target
Cabergoline	Alpha-1B adrenergic receptor	target
Cabergoline	Alpha-1D adrenergic receptor	target
Cabergoline	Beta-1 adrenergic receptor	target
Cabergoline	Beta-2 adrenergic receptor	target
Cabergoline	D(1) dopamine receptor	target
Cabergoline	P-glycoprotein 1	transporter
Chlorotrianisene	Estrogen receptor alpha	target
Chlorotrianisene	Cytochrome P450 19A1	enzyme
Pamidronic acid	Farnesyl pyrophosphate synthase	target
Pamidronic acid	Hydroxylapatite	target
Pamidronic acid	Geranylgeranyl pyrophosphate synthase	target
Pamidronic acid	Caspase-3	target
Pamidronic acid	Caspase-9	target
Floxuridine	Thymidylate synthase	target
Floxuridine	Thymidine phosphorylase	enzyme
Floxuridine	Cytochrome P450 2C9	enzyme
Floxuridine	Thyroxine-binding globulin	carrier
Aminoglutethimide	Cytochrome P450 19A1	target
Aminoglutethimide	Cytochrome P450 2C19	enzyme
Aminoglutethimide	Cytochrome P450 3A4	enzyme
Aminoglutethimide	Cholesterol side-chain cleavage enzyme, mitochondrial	target
Toremifene	Estrogen receptor alpha	target
Toremifene	Cytochrome P450 3A4	enzyme
Toremifene	P-glycoprotein 1	transporter
Toremifene	Cytochrome P450 1A1	enzyme
Toremifene	Sex hormone-binding globulin	target
Medroxyprogesterone acetate	Progesterone receptor	target
Medroxyprogesterone acetate	Estrogen receptor alpha	target
Medroxyprogesterone acetate	Cytochrome P450 3A4	enzyme
Medroxyprogesterone acetate	Cytochrome P450 2C8	enzyme
Medroxyprogesterone acetate	3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type 2	enzyme
Medroxyprogesterone acetate	Cytochrome P450 2C9	enzyme
Medroxyprogesterone acetate	Cytochrome P450 3A1	enzyme
Medroxyprogesterone acetate	Serum albumin	carrier
Medroxyprogesterone acetate	P-glycoprotein 1	target
Medroxyprogesterone acetate	GABA(A) Receptor	target
Medroxyprogesterone acetate	P-glycoprotein 1	transporter
Prednisone	Glucocorticoid receptor	target
Prednisone	Cytochrome P450 3A4	enzyme
Prednisone	P-glycoprotein 1	transporter
Prednisone	Solute carrier organic anion transporter family member 1A2	transporter
Prednisone	Cytochrome P450 2C19	enzyme
Prednisone	Serum albumin	carrier
Prednisone	Cytochrome P450 3A5	enzyme
Prednisone	Corticosteroid-binding globulin	carrier
Prednisone	Cytochrome P450 3A Subfamily	enzyme
Prednisone	Cytochrome P450 2A6	enzyme
Prednisone	Cytochrome P450 1B1	enzyme
Prednisone	Cytochrome P450 2B6	enzyme
Prednisone	Cytochrome P450 2C8	enzyme
Prednisone	Cytochrome P450 2C9	enzyme
Prednisone	Corticosteroid 11-beta-dehydrogenase isozyme 1	enzyme
Imiquimod	Toll-like receptor 7	target
Imiquimod	Toll-like receptor 8	target
Imiquimod	Cytochrome P450 3A4	enzyme
Uracil mustard	DNA	target
Prednisolone	Corticosteroid-binding globulin	carrier
Prednisolone	Cytochrome P450 3A4	enzyme
Prednisolone	Glucocorticoid receptor	target
Prednisolone	Solute carrier organic anion transporter family member 1A2	transporter
Prednisolone	P-glycoprotein 1	transporter
Prednisolone	Serum albumin	carrier
Testolactone	Cytochrome P450 19A1	target
Methylprednisolone	Glucocorticoid receptor	target
Methylprednisolone	Cytochrome P450 3A4	enzyme
Methylprednisolone	P-glycoprotein 1	transporter
Methylprednisolone	Cytochrome P450 3A Subfamily	enzyme
Methylprednisolone	Cytochrome P450 2A6	enzyme
Methylprednisolone	Cytochrome P450 1B1	enzyme
Methylprednisolone	Cytochrome P450 2B6	enzyme
Methylprednisolone	Cytochrome P450 2C8	enzyme
Methylprednisolone	Cytochrome P450 2C9	enzyme
Methylprednisolone	Cytochrome P450 2C19	enzyme
Methylprednisolone	Annexin A1	target
Methylprednisolone	20-ketosteroid reductase (20-hydroxysteroid dehydrogenase)	enzyme
Methylprednisolone	11beta-hydroxysteroid dehydrogenase	enzyme
Methylprednisolone	Serum albumin	carrier
Thalidomide	Cytochrome P450 2C19	enzyme
Thalidomide	Cytochrome P450 2C9	enzyme
Thalidomide	Prostaglandin G/H synthase 1	enzyme
Thalidomide	Prostaglandin G/H synthase 2	enzyme
Thalidomide	Cytochrome P450 3A5	enzyme
Thalidomide	DNA	target
Thalidomide	Protein cereblon	target
Thalidomide	alpha1-acid glycoprotein	target
Thalidomide	Cytochrome P450 3A4	enzyme
Thalidomide	Cytochrome P450 1A1	enzyme
Thalidomide	Cytochrome P450 2B6	enzyme
Trilostane	3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type 1	target
Trilostane	3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type 2	target
Trilostane	Estrogen receptor beta	target
Trilostane	Estrogen receptor alpha	target
Dexamethasone	Glucocorticoid receptor	target
Dexamethasone	Annexin A1	target
Dexamethasone	Nitric oxide synthase, inducible	target
Dexamethasone	Nuclear receptor subfamily 0 group B member 1	target
Dexamethasone	Cytochrome P450 3A4	enzyme
Dexamethasone	Cytochrome P450 3A5	enzyme
Dexamethasone	Cytochrome P450 3A7	enzyme
Dexamethasone	Bile salt export pump	transporter
Dexamethasone	P-glycoprotein 1	transporter
Dexamethasone	Canalicular multispecific organic anion transporter 1	transporter
Dexamethasone	Solute carrier organic anion transporter family member 1A2	transporter
Dexamethasone	ATP-binding cassette sub-family G member 2	transporter
Dexamethasone	Steroid 17-alpha-hydroxylase/17,20 lyase	enzyme
Dexamethasone	Cytochrome P450 1A1	enzyme
Dexamethasone	Cytochrome P450 2A6	enzyme
Dexamethasone	Cytochrome P450 2B6	enzyme
Dexamethasone	Cytochrome P450 2C19	enzyme
Dexamethasone	Cytochrome P450 2C8	enzyme
Dexamethasone	Cytochrome P450 2E1	enzyme
Dexamethasone	Cytochrome P450 3A43	enzyme
Dexamethasone	Cytochrome P450 4A11	enzyme
Dexamethasone	Nuclear receptor subfamily 1 group I member 2	target
Dexamethasone	Cytochrome P450 11B1, mitochondrial	enzyme
Dexamethasone	Serum albumin	carrier
Dexamethasone	Corticosteroid 11-beta-dehydrogenase isozyme 2	enzyme
Dexamethasone	Corticosteroid 11-beta-dehydrogenase isozyme 1	enzyme
Dexamethasone	Solute carrier family 22 member 8	transporter
8-azaguanine	Purine nucleoside phosphorylase	target
8-azaguanine	Cytochrome P450 1A2	enzyme
7-Hydroxystaurosporine	3-phosphoinositide-dependent protein kinase 1	target
Hadacidin	Adenylosuccinate synthetase	target
Hadacidin	Adenylosuccinate synthetase isozyme 1	target
Hadacidin	Adenylosuccinate synthetase	target
2-Methoxyestradiol	Hypoxia-inducible factor 1-alpha	target
2-Methoxyestradiol	Sex hormone-binding globulin	carrier
2-Methoxyestradiol	Catechol O-methyltransferase	target
2-Methoxyestradiol	Cytochrome P450 1A1	target
2-Methoxyestradiol	Cytochrome P450 1B1	target
2-Methoxyestradiol	Cytochrome P450 19A1	target
Geldanamycin	Heat shock protein HSP 90-alpha	target
Geldanamycin	Heat shock protein HSP 90-beta	target
Geldanamycin	Endoplasmin	target
Fumagillin	Methionine aminopeptidase 2	target
Patupilone	Tubulin alpha-3C/D chain	target
Patupilone	Tubulin beta chain	target
Patupilone	Tubulin beta-1 chain	target
Patupilone	Tubulin beta-4B chain	target
Patupilone	Tubulin beta-4A chain	target
Patupilone	Tubulin alpha-4A chain	target
Patupilone	Tubulin beta-3 chain	target
Patupilone	Tubulin alpha-1C chain	target
Patupilone	Tubulin alpha-8 chain	target
Patupilone	Tubulin alpha-1B chain	target
Patupilone	Tubulin alpha-1A chain	target
Patupilone	Cytochrome P450 3A4	enzyme
Sparfosic acid	Aspartate carbamoyltransferase catalytic chain	target
Sparfosic acid	CAD protein	target
Alvocidib	Glycogen phosphorylase, muscle form	target
Alvocidib	Cyclin-dependent kinase 7	target
Alvocidib	Cyclin-dependent kinase 5	target
Alvocidib	Cyclin-dependent kinase 9	target
Alvocidib	Cyclin-dependent kinase 1	target
Alvocidib	Cyclin-dependent kinase 6	target
Alvocidib	Epidermal growth factor receptor	target
Alvocidib	Cyclin-dependent kinase 4	target
Alvocidib	Cyclin-dependent kinase 8	target
Alvocidib	Cyclin-dependent kinase 2	target
Alvocidib	ATP-binding cassette sub-family G member 2	transporter
Alvocidib	Glycogen phosphorylase, brain form	target
Alvocidib	Glycogen phosphorylase, liver form	target
Alvocidib	UDP-glucuronosyltransferase 1-1	enzyme
2-(4-Chlorophenyl)-5-Quinoxalinecarboxamide	Poly [ADP-ribose] polymerase 1	target
Rhodamine 6G	HTH-type transcriptional regulator QacR	target
Rhodamine 6G	Acriflavine resistance protein B	target
Rhodamine 6G	Multidrug resistance-associated protein 1	transporter
Rhodamine 6G	P-glycoprotein 1	transporter
Batimastat	Neutrophil collagenase	target
Batimastat	Macrophage metalloelastase	target
Batimastat	Matrix metalloproteinase-16	target
Batimastat	Disintegrin and metalloproteinase domain-containing protein 28	target
Batimastat	A disintegrin and metalloproteinase with thrombospondin motifs 5	target
Tretazicar	Oxygen-insensitive NAD(P)H nitroreductase	target
Tretazicar	Ribosyldihydronicotinamide dehydrogenase [quinone]	target
Seocalcitol	Vitamin D3 receptor	target
Nebularine	Adenosine deaminase	target
Afimoxifene	Estrogen receptor alpha	target
Afimoxifene	Estrogen receptor beta	target
Afimoxifene	Estrogen-related receptor gamma	target
Afimoxifene	Trefoil factor 1	target
Afimoxifene	Steroid hormone receptor ERR1	target
Afimoxifene	Nuclear receptor subfamily 1 group I member 2	target
Afimoxifene	Sex hormone-binding globulin	target
Fleroxacin	DNA topoisomerase 2-alpha	target
Fleroxacin	DNA gyrase subunit A	target
Fleroxacin	DNA topoisomerase 4 subunit A	target
Metoprine	Histamine N-methyltransferase	target
Camptothecin	DNA topoisomerase 1	target
Camptothecin	P-glycoprotein 1	transporter
Camptothecin	ATP-binding cassette sub-family G member 2	transporter
Camptothecin	Serum albumin	carrier
Suramin	NAD-dependent protein deacylase sirtuin-5, mitochondrial	target
Suramin	Complement control protein C3	target
Suramin	Phospholipase A2, membrane associated	target
Suramin	Prothrombin	target
Suramin	P2Y purinoceptor 2	target
Suramin	Follicle-stimulating hormone receptor	target
Suramin	Ryanodine receptor 1	target
Suramin	Arylsulfatase A	enzyme
Suramin	Cytosolic phospholipase A2	enzyme
Urethane	Cytosolic phospholipase A2	enzyme
Urethane	Myeloperoxidase	enzyme
Urethane	Aldehyde oxidase	enzyme
Cyproterone acetate	Androgen receptor	target
Cyproterone acetate	Prostate-specific antigen	target
Cyproterone acetate	Cytochrome P450 3A4	enzyme
Cyproterone acetate	Cytochrome P450 19A1	enzyme
Tirapazamine	DNA	target
Tirapazamine	Cytochrome P450 2E1	enzyme
Halofuginone	Collagen alpha-1(I) chain	target
Halofuginone	72 kDa type IV collagenase	target
Vapreotide	Neurokinin 1 receptor	target
Vapreotide	Somatostatin receptor type 2	target
Vapreotide	Somatostatin receptor type 5	target
Vapreotide	Cytochrome P450 3A4	enzyme
Ranpirnase	DNA	target
Pirfenidone	Cytochrome P450 1A2	enzyme
Pirfenidone	Cytochrome P450 2C9	enzyme
Pirfenidone	Cytochrome P450 2C19	enzyme
Pirfenidone	Cytochrome P450 2D6	enzyme
Pirfenidone	Cytochrome P450 2E1	enzyme
Pirfenidone	Serum albumin	carrier
Pirfenidone	Cytochrome P450 3A4	enzyme
Pirfenidone	P-glycoprotein 1	transporter
Tipifarnib	Protein farnesyltransferase subunit beta	target
Tipifarnib	P-glycoprotein 1	transporter
Troxacitabine	DNA	target
Troxacitabine	Deoxycytidine kinase	enzyme
Amonafide	DNA topoisomerase 2-alpha	target
Amonafide	DNA topoisomerase 2-beta	target
Fenretinide	Retinol-binding protein 4	carrier
Tetrathiomolybdate	Amyloid beta A4 protein	target
Elsamitrucin	DNA	target
Elsamitrucin	DNA topoisomerase 1	target
Elsamitrucin	DNA topoisomerase 2-alpha	target
Gallium nitrate	Serotransferrin	carrier
Gallium nitrate	Ribonucleoside-diphosphate reductase subunit M2	target
Gallium nitrate	Protein-tyrosine-phosphatase	target
Gallium nitrate	Interleukin-1 beta	target
Gallium nitrate	Hydroxylapatite	target
Gallium nitrate	Osteocalcin	target
Gallium nitrate	V-type proton ATPase subunit B, brain isoform	target
Ecabet	NADPH oxidase organizer 1	target
Ecabet	Urease subunit alpha	target
Canertinib	Epidermal growth factor receptor	target
Motexafin gadolinium	Thioredoxin reductase 1, cytoplasmic	target
Motexafin gadolinium	Thioredoxin reductase 2, mitochondrial	target
Motexafin gadolinium	Ribonucleoside-diphosphate reductase subunit M2	target
Alanosine	Aspartate carbamoyltransferase catalytic chain	target
Alanosine	Adenylosuccinate synthetase isozyme 2	target
Alanosine	Adenylosuccinate synthetase isozyme 1	target
Alanosine	Cystine/glutamate transporter	transporter
Palifosfamide	DNA (cytosine-5)-methyltransferase 1	target
Trabedersen	Transforming growth factor beta-2	target
Irofulven	Far upstream element-binding protein 1	target
KOS-1584	Cytochrome P450 3A4	enzyme
Rubitecan	DNA topoisomerase 1	target
Garenoxacin	Cytochrome P450 1A2	enzyme
Seliciclib	Cyclin-dependent kinase 1	target
Seliciclib	Cyclin-dependent kinase 2	target
Seliciclib	Mitogen-activated protein kinase 3	target
Seliciclib	Mitogen-activated protein kinase 1	target
Seliciclib	Cyclin-dependent kinase 7	target
Seliciclib	Cyclin-dependent kinase 9	target
Seliciclib	Casein kinase I isoform epsilon	target
Seliciclib	Prostaglandin G/H synthase 2	enzyme
Eflornithine	Ornithine decarboxylase	target
Exisulind	cAMP-specific 3',5'-cyclic phosphodiesterase 4D	target
Exisulind	cAMP-specific 3',5'-cyclic phosphodiesterase 4C	target
Exisulind	cGMP-specific 3',5'-cyclic phosphodiesterase	target
Exisulind	cGMP-dependent 3',5'-cyclic phosphodiesterase	target
Exisulind	Glutathione S-transferase P	target
Exisulind	Aldose reductase	target
Exisulind	Aldo-keto reductase family 1 member B10	target
Annamycin	DNA topoisomerase 2-alpha	target
Annamycin	DNA	target
Annamycin	P-glycoprotein 1	transporter
Endostatin	72 kDa type IV collagenase	target
Endostatin	Matrix metalloproteinase-9	target
Endostatin	Collagenase 3	target
Endostatin	Focal adhesion kinase 1	target
Endostatin	E-selectin	target
Endostatin	Cytochrome P450 19A1	enzyme
Tezacitabine	Ribonucleoside-diphosphate reductase large subunit	target
Tezacitabine	Thymidine phosphorylase	enzyme
Semaxanib	Vascular endothelial growth factor receptor 2	target
Semaxanib	Prostaglandin G/H synthase 2	enzyme
Porfiromycin	Xanthine dehydrogenase/oxidase	enzyme
Methyltestosterone	Cytochrome P450 2B6	enzyme
Methyltestosterone	Cytochrome P450 3A4	enzyme
Methyltestosterone	Androgen receptor	target
Methyltestosterone	Solute carrier organic anion transporter family member 1A2	transporter
Methyltestosterone	Solute carrier family 22 member 8	transporter
Methyltestosterone	Serum albumin	carrier
Methyltestosterone	Sex hormone-binding globulin	carrier
Methyltestosterone	Estrogen receptor alpha	target
Methyltestosterone	Cytochrome P450 19A1	enzyme
Besifloxacin	DNA topoisomerase 4 subunit A	target
Besifloxacin	DNA topoisomerase 4 subunit A	target
Besifloxacin	DNA gyrase subunit A	target
Besifloxacin	DNA gyrase subunit A	target
Besifloxacin	Cytochrome P450 1A2	enzyme
Hydroxyprogesterone caproate	Progesterone receptor	target
Hydroxyprogesterone caproate	Cytochrome P450 3A4	enzyme
Hydroxyprogesterone caproate	Cytochrome P450 3A5	enzyme
Hydroxyprogesterone caproate	Cytochrome P450 2C19	enzyme
Lanreotide	Somatostatin receptor type 2	target
Lanreotide	Somatostatin receptor type 5	target
Lanreotide	Cytochrome P450 3A4	enzyme
Phenylbutyric acid	Aromatic-amino-acid aminotransferase	target
Phenylbutyric acid	Histone deacetylase	target
Veliparib	Poly [ADP-ribose] polymerase 1	target
Veliparib	Poly [ADP-ribose] polymerase 2	target
Hexestrol	Aldo-keto reductase family 1 member C1	target
Hexestrol	Estrogen receptor alpha	target
Hexestrol	Nuclear receptor subfamily 1 group I member 2	target
Hexestrol	Nuclear receptor subfamily 1 group I member 3	target
Nocodazole	Hematopoietic prostaglandin D synthase	target
Puromycin	60S ribosomal protein L10-like	target
Puromycin	60S ribosomal protein L13a	target
Puromycin	60S ribosomal protein L23	target
Puromycin	60S ribosomal protein L15	target
Puromycin	60S ribosomal protein L19	target
Puromycin	60S ribosomal protein L23a	target
Puromycin	Probable ribosome biogenesis protein RLP24	target
Puromycin	60S ribosomal protein L26-like 1	target
Puromycin	60S ribosomal protein L8	target
Puromycin	60S ribosomal protein L37	target
Puromycin	60S ribosomal protein L3	target
Puromycin	60S ribosomal protein L11	target
Puromycin	Leucyl/phenylalanyl-tRNA--protein transferase	target
Formestane	Cytochrome P450 3A4	enzyme
Flumequine	Cytochrome P450 1A2	enzyme
Siltuximab	Interleukin-6	target
Siltuximab	Cytochrome P450 3A4	enzyme
Dienogest	Cytochrome P450 3A4	enzyme
Dienogest	Progesterone receptor	target
Dienogest	Androgen receptor	target
Niguldipine	Alpha-1A adrenergic receptor	target
Niguldipine	Cytochrome P450 3A4	enzyme
Niguldipine	P-glycoprotein 1	transporter
Curcumin	Peroxisome proliferator-activated receptor gamma	target
Curcumin	Vitamin D3 receptor	target
Curcumin	Multidrug resistance-associated protein 5	target
Curcumin	Carbonyl reductase [NADPH] 1	target
Curcumin	Glutathione S-transferase P	target
Curcumin	Cytochrome P450 2C9	enzyme
Curcumin	Cytochrome P450 3A4	enzyme
Curcumin	Cytochrome P450 2B6	enzyme
Curcumin	Cytochrome P450 1A2	enzyme
Curcumin	Cytochrome P450 2D6	enzyme
Curcumin	Glutathione S-transferase A1	enzyme
Curcumin	Glutathione S-transferase Mu 1	enzyme
Curcumin	Glutathione S-transferase P	enzyme
Curcumin	P-glycoprotein 1	transporter
Bryostatin 1	Cytochrome P450 3A4	enzyme
Bryostatin 1	Protein kinase C alpha type	target
Bryostatin 1	Protein kinase C epsilon type	target
Bryostatin 1	Caspase-8	target
Bryostatin 1	Protein unc-13 homolog B	target
Bryostatin 1	Serine/threonine-protein kinase D1	target
Bryostatin 1	T-lymphocyte activation antigen CD86	target
Bryostatin 1	Prostaglandin G/H synthase 2	target
Bryostatin 1	G1/S-specific cyclin-D1	target
Bryostatin 1	Tumor necrosis factor	target
Talazoparib	Poly [ADP-ribose] polymerase 1	target
Talazoparib	Poly [ADP-ribose] polymerase 2	target
Talazoparib	P-glycoprotein 1	transporter
Talazoparib	ATP-binding cassette sub-family G member 2	transporter
Tremelimumab	Cytotoxic T-lymphocyte protein 4	target
Niraparib	Poly [ADP-ribose] polymerase 1	target
Niraparib	Poly [ADP-ribose] polymerase 2	target
Niraparib	Carboxylesterase	enzyme
Niraparib	Cytochrome P450 1A2	enzyme
Niraparib	ATP-binding cassette sub-family G member 2	transporter
Niraparib	Multidrug and toxin extrusion protein 1	transporter
Niraparib	Multidrug and toxin extrusion protein 2	transporter
Niraparib	P-glycoprotein 1	transporter
Niraparib	Serum albumin	carrier
Saracatinib	Cytochrome P450 3A4	enzyme
Entinostat	Histone deacetylase	target
Infigratinib	Cytochrome P450 3A4	enzyme
Infigratinib	Multidrug and toxin extrusion protein 1	transporter
Infigratinib	ATP-binding cassette sub-family G member 2	transporter
Infigratinib	Bile salt export pump	transporter
Infigratinib	Solute carrier family 22 member 1	transporter
Infigratinib	Solute carrier family 22 member 2	transporter
Infigratinib	Multidrug and toxin extrusion protein 2	transporter
Infigratinib	P-glycoprotein 1	transporter
Infigratinib	Solute carrier organic anion transporter family member 1B1	transporter
Infigratinib	Solute carrier organic anion transporter family member 1B3	transporter
Infigratinib	Apolipoproteins	carrier
Infigratinib	Dimethylaniline monooxygenase [N-oxide-forming] 3	enzyme
Infigratinib	Fibroblast growth factor receptor 1	target
Infigratinib	Fibroblast growth factor receptor 2	target
Infigratinib	Fibroblast growth factor receptor 3	target
Infigratinib	Fibroblast growth factor receptor 4	target
6-O-benzylguanine	Cytochrome P450 3A4	enzyme
Carboxyamidotriazole	Cytochrome P450 3A4	enzyme
Epigallocatechin gallate	Aryl hydrocarbon receptor	target
Epigallocatechin gallate	DNA (cytosine-5)-methyltransferase 1	target
Epigallocatechin gallate	Dihydrofolate reductase, mitochondrial	target
Epofolate	Cytochrome P450 3A4	enzyme
Rucaparib	Poly [ADP-ribose] polymerase 1	target
Rucaparib	Poly [ADP-ribose] polymerase 2	target
Rucaparib	Poly [ADP-ribose] polymerase 3	target
Rucaparib	Cytochrome P450 2D6	enzyme
Rucaparib	Cytochrome P450 1A2	enzyme
Rucaparib	Cytochrome P450 3A4	enzyme
Rucaparib	P-glycoprotein 1	transporter
Rucaparib	ATP-binding cassette sub-family G member 2	transporter
Rucaparib	Multidrug and toxin extrusion protein 1	transporter
Rucaparib	Multidrug and toxin extrusion protein 2	transporter
Rucaparib	Solute carrier family 22 member 1	transporter
Rucaparib	Multidrug resistance-associated protein 4	transporter
Rucaparib	Solute carrier organic anion transporter family member 1B1	transporter
Rucaparib	Solute carrier organic anion transporter family member 1B3	transporter
Rucaparib	Solute carrier family 22 member 6	transporter
Rucaparib	Solute carrier family 22 member 8	transporter
Rucaparib	Cytochrome P450 3A5	enzyme
Rucaparib	Cytochrome P450 3A7	enzyme
Rucaparib	Cytochrome P450 3A43	enzyme
Rucaparib	Cytochrome P450 2C19	enzyme
Rucaparib	Cytochrome P450 2C9	enzyme
Rucaparib	Cytochrome P450 2C8	enzyme
Rucaparib	UDP-glucuronosyltransferase 1-1	enzyme
Navitoclax	Apoptosis regulator Bcl-2	target
Navitoclax	Bcl-2-like protein 2	target
Navitoclax	Bcl2 antagonist of cell death	target
Indirubin	Cytochrome P450 1A1	target
Indirubin	Aryl hydrocarbon receptor	target
9-aminocamptothecin	Cytochrome P450 3A4	enzyme
Onapristone	Glucocorticoid receptor	target
Onapristone	Probable G-protein coupled receptor 133	target
Phenethyl Isothiocyanate	Actin, aortic smooth muscle	target
Phenethyl Isothiocyanate	Actin, cytoplasmic 1	target
Phenethyl Isothiocyanate	ATP synthase subunit beta, mitochondrial	target
Phenethyl Isothiocyanate	ATP synthase subunit e, mitochondrial	target
Phenethyl Isothiocyanate	ATP synthase subunit g, mitochondrial	target
Phenethyl Isothiocyanate	Cytochrome b5 type B	target
Phenethyl Isothiocyanate	Diablo homolog, mitochondrial	target
Phenethyl Isothiocyanate	F-box only protein 41	target
Phenethyl Isothiocyanate	Heterogeneous nuclear ribonucleoprotein F	target
Phenethyl Isothiocyanate	Heterogeneous nuclear ribonucleoprotein K	target
Phenethyl Isothiocyanate	Heat shock 70 kDa protein 4	target
Phenethyl Isothiocyanate	Heat shock protein beta-1	target
Phenethyl Isothiocyanate	10 kDa heat shock protein, mitochondrial	target
Phenethyl Isothiocyanate	Heat shock protein 105 kDa	target
Phenethyl Isothiocyanate	NADH-ubiquinone oxidoreductase chain 1	target
Phenethyl Isothiocyanate	Nuclear migration protein nudC	target
Phenethyl Isothiocyanate	Pappalysin-1	target
Phenethyl Isothiocyanate	Proteasome subunit alpha type-3	target
Phenethyl Isothiocyanate	26S protease regulatory subunit 6A	target
Phenethyl Isothiocyanate	Ran-specific GTPase-activating protein	target
Phenethyl Isothiocyanate	Protein S100-A10	target
Phenethyl Isothiocyanate	Splicing factor 3A subunit 3	target
Phenethyl Isothiocyanate	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily E member 1	target
Phenethyl Isothiocyanate	Succinyl-CoA ligase [GDP-forming] subunit beta, mitochondrial	target
Phenethyl Isothiocyanate	Tumor protein D54	target
Phenethyl Isothiocyanate	Tropomyosin alpha-1 chain	target
Phenethyl Isothiocyanate	Tropomyosin alpha-3 chain	target
Phenethyl Isothiocyanate	Tropomyosin alpha-4 chain	target
Phenethyl Isothiocyanate	Tubulin alpha-1A chain	target
Phenethyl Isothiocyanate	Tubulin alpha-3C/D chain	target
Phenethyl Isothiocyanate	Tubulin alpha-4A chain	target
Phenethyl Isothiocyanate	Tubulin beta-1 chain	target
Phenethyl Isothiocyanate	Tubulin beta-2A chain	target
Phenethyl Isothiocyanate	Tubulin beta-3 chain	target
Phenethyl Isothiocyanate	Tubulin beta-4B chain	target
Phenethyl Isothiocyanate	Thioredoxin	target
Phenethyl Isothiocyanate	Ubiquitin carboxyl-terminal hydrolase isozyme L1	target
Phenethyl Isothiocyanate	Ubiquitin carboxyl-terminal hydrolase 14	target
Phenethyl Isothiocyanate	Transitional endoplasmic reticulum ATPase	target
Phenethyl Isothiocyanate	Vimentin	target
Phenethyl Isothiocyanate	14-3-3 protein beta/alpha	target
Phenethyl Isothiocyanate	14-3-3 protein epsilon	target
Phenethyl Isothiocyanate	14-3-3 protein eta	target
Phenethyl Isothiocyanate	14-3-3 protein theta	target
Phenethyl Isothiocyanate	14-3-3 protein zeta/delta	target
Lometrexol	Dihydrofolate reductase	target
Hypericin	Serum albumin	carrier
Hypericin	Glutathione S-transferase A1	target
Hypericin	Glutathione S-transferase P	target
Nedaplatin	Glutathione	target
Nedaplatin	DNA	target
Iniparib	Poly [ADP-ribose] polymerase 1	target
Tretamine	Cholinesterase	enzyme
Masoprocol	Arachidonate 5-lipoxygenase	target
Masoprocol	Sex hormone-binding globulin	target
Masoprocol	Transient receptor potential cation channel subfamily M member 7	target
Anagrelide	cGMP-inhibited 3',5'-cyclic phosphodiesterase A	target
Anagrelide	Cytochrome P450 1A2	enzyme
Aminolevulinic acid	Delta-aminolevulinic acid dehydratase	target
Aminolevulinic acid	Solute carrier family 15 member 1	transporter
Aminolevulinic acid	Solute carrier family 15 member 2	transporter
Ixabepilone	Tubulin beta-3 chain	target
Ixabepilone	Cytochrome P450 3A4	enzyme
Ixabepilone	P-glycoprotein 1	transporter
Vintafolide	Folate receptor beta	target
Vintafolide	Folate receptor gamma	target
Vintafolide	Folate receptor alpha	target
Ridaforolimus	Serine/threonine-protein kinase mTOR	target
Ridaforolimus	Cytochrome P450 3A4	enzyme
Pralatrexate	Dihydrofolate reductase	target
Pralatrexate	Thymidylate synthase	target
Pralatrexate	Folate transporter 1	transporter
Pralatrexate	Canalicular multispecific organic anion transporter 1	transporter
Pralatrexate	ATP-binding cassette sub-family G member 2	transporter
Pralatrexate	Serum albumin	carrier
Pralatrexate	Folylpolyglutamate synthase, mitochondrial	target
Pralatrexate	Proton-coupled folate transporter	transporter
Pralatrexate	Canalicular multispecific organic anion transporter 2	transporter
Pralatrexate	Solute carrier organic anion transporter family member 1B3	transporter
Efaproxiral	Hemoglobin subunit alpha	target
Efaproxiral	Hemoglobin subunit beta	target
Cabozantinib	Cytochrome P450 3A4	enzyme
Cabozantinib	Cytochrome P450 2C9	enzyme
Cabozantinib	Hepatocyte growth factor receptor	target
Cabozantinib	Vascular endothelial growth factor receptor 2	target
Cabozantinib	Proto-oncogene tyrosine-protein kinase receptor Ret	target
Cabozantinib	Cytochrome P450 2C8	enzyme
Dinutuximab	GD2 disialoganglioside	target
Sonidegib	Smoothened homolog	target
Sonidegib	Cytochrome P450 3A4	enzyme
Vinflunine	ATP-binding cassette sub-family B member 5	transporter
Vinflunine	P-glycoprotein 1	transporter
Vinflunine	Serum albumin	carrier
Vinflunine	alpha1-acid glycoprotein	carrier
Vinflunine	Cytochrome P450 3A4	enzyme
Vinflunine	Tubulin beta chain	target
Tivozanib	Cytochrome P450 3A4	enzyme
Tivozanib	Serum albumin	carrier
Tivozanib	Vascular endothelial growth factor receptor 1	target
Tivozanib	Vascular endothelial growth factor receptor 2	target
Tivozanib	Vascular endothelial growth factor receptor 3	target
Tivozanib	Mast/stem cell growth factor receptor Kit	target
Tivozanib	Platelet-derived growth factor receptor beta	target
Tivozanib	P-glycoprotein 1	transporter
Tivozanib	ATP-binding cassette sub-family G member 2	transporter
Tivozanib	Receptor-type tyrosine-protein kinase FLT3	target
Tivozanib	Platelet-derived growth factor receptor alpha	target
Tivozanib	Protein-tyrosine kinase 6	target
Tivozanib	Angiopoietin-1 receptor	target
Tivozanib	Fibroblast growth factor receptor 1	target
Tivozanib	Hepatocyte growth factor receptor	target
Interferon alfa-2b	Interferon alpha/beta receptor 2	target
Interferon alfa-2b	Interferon alpha/beta receptor 1	target
Interferon alfa-2b	Cytochrome P450 1A2	enzyme
Cobimetinib	Dual specificity mitogen-activated protein kinase kinase 1	target
Cobimetinib	Cytochrome P450 3A4	enzyme
Cobimetinib	Solute carrier organic anion transporter family member 1B1	transporter
Cobimetinib	Solute carrier organic anion transporter family member 1B3	transporter
Cobimetinib	ATP-binding cassette sub-family G member 2	transporter
Cobimetinib	P-glycoprotein 1	transporter
Cobimetinib	UDP-glucuronosyltransferase 2B7	enzyme
Cobimetinib	Cytochrome P450 2D6	enzyme
Cobimetinib	Cytochrome P450 3A5	enzyme
Cobimetinib	Alpha-1-acid glycoprotein 1	carrier
Inotuzumab ozogamicin	P-glycoprotein 1	transporter
Inotuzumab ozogamicin	B-cell receptor CD22	target
Olaratumab	Platelet-derived growth factor receptor alpha	target
Elotuzumab	SLAM family member 7	target
Degarelix	Gonadotropin-releasing hormone receptor	target
Buserelin	Lutropin-choriogonadotropic hormone receptor	target
Buserelin	Gonadotropin-releasing hormone receptor	target
Buserelin	Cytochrome P450 19A1	enzyme
Enzalutamide	Serum albumin	carrier
Enzalutamide	Cytochrome P450 2C8	enzyme
Enzalutamide	Cytochrome P450 3A4	enzyme
Enzalutamide	Androgen receptor	target
Enzalutamide	Cytochrome P450 2C9	enzyme
Enzalutamide	Cytochrome P450 2C19	enzyme
Enzalutamide	Cytochrome P450 2B6	enzyme
Enzalutamide	Cytochrome P450 3A5	enzyme
Enzalutamide	P-glycoprotein 1	transporter
Alectinib	ALK tyrosine kinase receptor	target
Alectinib	ATP-binding cassette sub-family G member 2	transporter
Alectinib	P-glycoprotein 1	transporter
Venetoclax	Apoptosis regulator Bcl-2	target
Venetoclax	Cytochrome P450 3A4	enzyme
Venetoclax	P-glycoprotein 1	transporter
Venetoclax	ATP-binding cassette sub-family G member 2	transporter
Venetoclax	Solute carrier organic anion transporter family member 1B1	transporter
Atezolizumab	Programmed cell death 1 ligand 1	target
Atezolizumab	Programmed cell death protein 1	target
Durvalumab	Programmed cell death 1 ligand 1	target
Durvalumab	Programmed cell death protein 1	target
Ribociclib	Cyclin-dependent kinase 4	target
Ribociclib	Cyclin-dependent kinase 6	target
Ribociclib	Cytochrome P450 3A4	enzyme
Avelumab	Programmed cell death 1 ligand 1	target
Avelumab	Programmed cell death protein 1	target
Genistein	Estrogen receptor beta	target
Genistein	DNA topoisomerase 2-alpha	target
Genistein	Protein-tyrosine kinase 2-beta	target
Genistein	P-glycoprotein 1	transporter
Genistein	Multidrug resistance-associated protein 1	transporter
Genistein	ATP-binding cassette sub-family G member 2	transporter
Genistein	Cytochrome P450 1A2	enzyme
Genistein	Nuclear receptor coactivator 1	target
Genistein	Estrogen receptor alpha	target
Genistein	Nuclear receptor coactivator 2	target
Genistein	Transthyretin	carrier
Genistein	Steroid hormone receptor ERR2	target
Genistein	Steroid hormone receptor ERR1	target
Genistein	Nuclear receptor subfamily 1 group I member 2	target
Genistein	RAC-alpha serine/threonine-protein kinase	target
Genistein	G-protein coupled estrogen receptor 1	target
Genistein	Cytochrome P450 1B1	target
Genistein	Sex hormone-binding globulin	target
Genistein	Cytochrome P450 1A1	enzyme
Genistein	Solute carrier organic anion transporter family member 1B1	transporter
Genistein	Solute carrier organic anion transporter family member 2B1	transporter
Genistein	Cytochrome P450 2C8	enzyme
Genistein	Cytochrome P450 2C9	enzyme
Genistein	Cytochrome P450 3A1	enzyme
Genistein	Cytochrome P450 3A2	enzyme
Genistein	Cytochrome P450 3A4	enzyme
Genistein	Cystic fibrosis transmembrane conductance regulator	target
Trifluridine	Thymidylate synthase	target
Trifluridine	DNA	target
Trifluridine	Thymidine kinase, cytosolic	enzyme
Trifluridine	Thymidine phosphorylase	enzyme
Trifluridine	Solute carrier family 22 member 6	transporter
Trifluridine	Sodium/nucleoside cotransporter 1	transporter
Trifluridine	Equilibrative nucleoside transporter 1	transporter
Trifluridine	Equilibrative nucleoside transporter 2	transporter
Trifluridine	Serum albumin	carrier
Pracinostat	Histone deacetylase 1	target
Pracinostat	Histone deacetylase 2	target
Pracinostat	Histone deacetylase 3	target
Pracinostat	Histone deacetylase 6	target
Mocetinostat	Histone deacetylase 1	target
Mocetinostat	Histone deacetylase 3	target
Mocetinostat	Histone deacetylase 2	target
Abexinostat	Histone deacetylase 1	target
Abexinostat	Histone deacetylase	target
Givinostat	Histone deacetylase	target
Valproic acid	Histone deacetylase 9	target
Valproic acid	Short/branched chain specific acyl-CoA dehydrogenase, mitochondrial	target
Valproic acid	Cytochrome P450 2A6	enzyme
Valproic acid	Cytochrome P450 2B6	enzyme
Valproic acid	Cytochrome P450 2C9	enzyme
Valproic acid	Solute carrier family 22 member 5	transporter
Valproic acid	Solute carrier family 22 member 6	transporter
Valproic acid	Solute carrier family 22 member 8	transporter
Valproic acid	Monocarboxylate transporter 1	transporter
Valproic acid	Solute carrier family 22 member 7	transporter
Valproic acid	Cytochrome P450 3A5	enzyme
Valproic acid	UDP-glucuronosyltransferase 1-9	enzyme
Valproic acid	Prostaglandin G/H synthase 1	enzyme
Valproic acid	Cytochrome P450 1A2	enzyme
Valproic acid	Cytochrome P450 2C19	enzyme
Valproic acid	Cytochrome P450 3A4	enzyme
Valproic acid	UDP-glucuronosyltransferase 1-4	enzyme
Valproic acid	UDP-glucuronosyltransferase 1-8	enzyme
Valproic acid	UDP-glucuronosyltransferase 1-10	enzyme
Valproic acid	UDP-glucuronosyltransferase 1-6	enzyme
Valproic acid	UDP-glucuronosyltransferase 1-3	enzyme
Valproic acid	UDP-glucuronosyltransferase 2B7	enzyme
Valproic acid	UDP-glucuronosyltransferase 2B15	enzyme
Valproic acid	2-oxoglutarate dehydrogenase, mitochondrial	target
Valproic acid	Succinate-semialdehyde dehydrogenase, mitochondrial	target
Valproic acid	Sodium channel protein	target
Valproic acid	Histone deacetylase 2	target
Valproic acid	Peroxisome proliferator-activated receptor alpha	target
Valproic acid	Peroxisome proliferator-activated receptor delta	target
Valproic acid	Peroxisome proliferator-activated receptor gamma	target
Valproic acid	Serum albumin	carrier
Valproic acid	UDP-glucuronosyltransferase 1-1	enzyme
Valproic acid	Solute carrier organic anion transporter family member 2B1	transporter
Valproic acid	Histone deacetylase	target
Valproic acid	Cyclin-dependent kinase inhibitor 1	target
Valproic acid	Hepatocyte growth factor	target
Valproic acid	Ornithine decarboxylase	target
Valproic acid	Programmed cell death 1 ligand 1	target
Bufexamac	Prostaglandin G/H synthase 1	target
Bufexamac	Prostaglandin G/H synthase 2	target
Bufexamac	Histone deacetylase 6	target
Bufexamac	Histone deacetylase 10	target
Tetrandrine	P-glycoprotein 1	target
Tetrandrine	Cytochrome P450 3A4	enzyme
Tetrandrine	P-glycoprotein 1	transporter
Dofequidar	ATP-binding cassette sub-family B member 5	target
Dofequidar	P-glycoprotein 1	target
Dofequidar	P-glycoprotein 1	transporter
Dexniguldipine	P-glycoprotein 1	target
Dexniguldipine	Cytochrome P450 3A4	enzyme
Aldoxorubicin	DNA topoisomerase 2-alpha	target
Peginterferon alfa-2a	Interferon alpha/beta receptor 2	target
Peginterferon alfa-2a	Interferon alpha/beta receptor 1	target
Peginterferon alfa-2a	Cytochrome P450 1A2	enzyme
Methylprednisolone hemisuccinate	Cytochrome P450 3A4	enzyme
Methylprednisolone hemisuccinate	Cytochrome P450 3A5	enzyme
Prednisone acetate	Cytochrome P450 3A4	enzyme
Prednisone acetate	Cytochrome P450 3A5	enzyme
Moxetumomab pasudotox	B-cell receptor CD22	target
Moxetumomab pasudotox	Elongation factor 2	target
Dacomitinib	Cytochrome P450 2D6	enzyme
Dacomitinib	Serum albumin	carrier
Dacomitinib	Cytochrome P450 3A4	enzyme
Dacomitinib	Cytochrome P450 2C9	enzyme
Dacomitinib	UDP-glucuronosyltransferase 1-1	enzyme
Dacomitinib	P-glycoprotein 1	transporter
Dacomitinib	ATP-binding cassette sub-family G member 2	transporter
Dacomitinib	Solute carrier family 22 member 1	transporter
Dacomitinib	Epidermal growth factor receptor	target
Brequinar	Dihydroorotate dehydrogenase (quinone), mitochondrial	target
Piritrexim	Dihydrofolate reductase	target
7-ethyl-10-hydroxycamptothecin	DNA topoisomerase 1	target
7-ethyl-10-hydroxycamptothecin	Cytochrome P450 3A4	enzyme
TNP-470	Methionine aminopeptidase 2	target
Gilteritinib	Serum albumin	carrier
Gilteritinib	Cytochrome P450 3A4	enzyme
Gilteritinib	Receptor-type tyrosine-protein kinase FLT3	target
Gilteritinib	Serotonin Receptors	target
Gilteritinib	P-glycoprotein 1	transporter
Gilteritinib	Multidrug and toxin extrusion protein 1	transporter
Gilteritinib	ATP-binding cassette sub-family G member 2	transporter
Gilteritinib	Solute carrier family 22 member 1	transporter
Gilteritinib	Tyrosine-protein kinase receptor UFO	target
Gilteritinib	ALK tyrosine kinase receptor	target
Tagraxofusp	Interleukin-3 receptor subunit alpha	target
Vadimezan	UDP-glucuronosyltransferase 1-9	enzyme
Vadimezan	UDP-glucuronosyltransferase 2B7	enzyme
Vadimezan	Cytochrome P450 1A2	enzyme
Glasdegib	Cytochrome P450 3A4	enzyme
Glasdegib	Smoothened homolog	target
Glasdegib	Cytochrome P450 2C8	enzyme
Glasdegib	UDP-glucuronosyltransferase 1-9	enzyme
Glasdegib	Serum albumin	carrier
Glasdegib	P-glycoprotein 1	transporter
Glasdegib	ATP-binding cassette sub-family G member 2	transporter
Glasdegib	Multidrug and toxin extrusion protein 1	transporter
Glasdegib	Multidrug and toxin extrusion protein 2	transporter
Plitidepsin	Cytochrome P450 3A4	enzyme
Plitidepsin	Cytochrome P450 2A6	enzyme
Plitidepsin	Cytochrome P450 2E1	enzyme
Plitidepsin	Cytochrome P450 4A11	enzyme
Plitidepsin	Elongation factor 1-alpha 2	target
Encorafenib	Cytochrome P450 3A4	enzyme
Encorafenib	Cytochrome P450 2C19	enzyme
Encorafenib	Cytochrome P450 2D6	enzyme
Encorafenib	Serine/threonine-protein kinase B-raf	target
Encorafenib	G1/S-specific cyclin-D1	target
Icotinib	Epidermal growth factor receptor	target
Icotinib	Cytochrome P450 3A4	enzyme
Icotinib	Cytochrome P450 1A2	enzyme
Icotinib	Cytochrome P450 3A5	enzyme
Neratinib	Cytochrome P450 3A4	enzyme
Neratinib	Dimethylaniline monooxygenase [N-oxide-forming] 3	enzyme
Neratinib	P-glycoprotein 1	transporter
Neratinib	Epidermal growth factor receptor	target
Neratinib	Serum albumin	carrier
Neratinib	alpha1-acid glycoprotein	carrier
Binimetinib	Interleukin-6	target
Binimetinib	Tumor necrosis factor	target
Binimetinib	Interleukin-1 beta	target
Binimetinib	UDP-glucuronosyltransferase 1-1	enzyme
Binimetinib	Cytochrome P450 1A2	enzyme
Binimetinib	Cytochrome P450 2C19	enzyme
Binimetinib	Mitogen-activated protein kinase kinase kinase 1	target
Binimetinib	Dual specificity mitogen-activated protein kinase kinase 2	target
Abemaciclib	Multidrug and toxin extrusion protein 1	transporter
Abemaciclib	Multidrug and toxin extrusion protein 2	transporter
Abemaciclib	Cyclin-dependent kinase 4	target
Abemaciclib	Cyclin-dependent kinase 6	target
Abemaciclib	Serum albumin	carrier
Abemaciclib	alpha1-acid glycoprotein	carrier
Abemaciclib	Cytochrome P450 3A4	enzyme
Abemaciclib	P-glycoprotein 1	transporter
Abemaciclib	ATP-binding cassette sub-family G member 2	transporter
Abemaciclib	Solute carrier family 22 member 2	transporter
Abemaciclib	Cytochrome P450 1A2	enzyme
Abemaciclib	Cytochrome P450 2B6	enzyme
Abemaciclib	Cytochrome P450 2C8	enzyme
Abemaciclib	Cytochrome P450 2C9	enzyme
Abemaciclib	Cytochrome P450 2D6	enzyme
Lorlatinib	ALK tyrosine kinase receptor	target
Lorlatinib	Cytochrome P450 3A Subfamily	enzyme
Lorlatinib	Cytochrome P450 3A5	enzyme
Lorlatinib	Cytochrome P450 2B6	enzyme
Lorlatinib	Cytochrome P450 2C8	enzyme
Lorlatinib	Cytochrome P450 2C19	enzyme
Lorlatinib	UDP-glucuronosyltransferase 1-3	enzyme
Lorlatinib	Cytochrome P450 3A4	enzyme
Brigatinib	ALK tyrosine kinase receptor	target
Brigatinib	Epidermal growth factor receptor	target
Brigatinib	Tyrosine-protein kinase ABL1	target
Brigatinib	Insulin-like growth factor 1 receptor	target
Brigatinib	Receptor-type tyrosine-protein kinase FLT3	target
Brigatinib	Cytochrome P450 2C8	enzyme
Brigatinib	Cytochrome P450 3A4	enzyme
Brigatinib	Insulin receptor	target
Brigatinib	Hepatocyte growth factor receptor	target
Brigatinib	Receptor tyrosine-protein kinase erbB-4	target
Brigatinib	Receptor tyrosine-protein kinase erbB-2	target
Brigatinib	ATP-binding cassette sub-family B member 5	transporter
Brigatinib	ATP-binding cassette sub-family G member 2	transporter
Brigatinib	Solute carrier family 22 member 1	transporter
Brigatinib	Multidrug and toxin extrusion protein 1	transporter
Brigatinib	Multidrug and toxin extrusion protein 2	transporter
Brigatinib	Cytochrome P450 3A Subfamily	enzyme
Copanlisib	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform	target
Copanlisib	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform	target
Copanlisib	Cytochrome P450 3A4	enzyme
Copanlisib	Cytochrome P450 3A5	enzyme
Copanlisib	Cytochrome P450 3A7	enzyme
Copanlisib	P-glycoprotein 1	transporter
Copanlisib	ATP-binding cassette sub-family G member 2	transporter
Copanlisib	Multidrug and toxin extrusion protein 2	transporter
Copanlisib	Serum albumin	carrier
Copanlisib	Cytochrome P450 1A1	enzyme
Mogamulizumab	C-C chemokine receptor type 4	target
Olmutinib	Epidermal growth factor receptor	target
Enasidenib	Cytochrome P450 1A2	enzyme
Enasidenib	Cytochrome P450 2B6	enzyme
Enasidenib	Isocitrate dehydrogenase [NADP], mitochondrial	target
Enasidenib	Cytochrome P450 2C8	enzyme
Enasidenib	Cytochrome P450 2C9	enzyme
Enasidenib	Cytochrome P450 2C19	enzyme
Enasidenib	Cytochrome P450 2D6	enzyme
Enasidenib	Cytochrome P450 3A4	enzyme
Enasidenib	UDP-glucuronosyltransferase 1-1	enzyme
Enasidenib	UDP-glucuronosyltransferase 1-3	enzyme
Enasidenib	UDP-glucuronosyltransferase 1-4	enzyme
Enasidenib	UDP-glucuronosyltransferase 1-9	enzyme
Enasidenib	UDP-glucuronosyltransferase 2B7	enzyme
Enasidenib	UDP-glucuronosyltransferase 2B15	enzyme
Enasidenib	P-glycoprotein 1	transporter
Enasidenib	ATP-binding cassette sub-family G member 2	transporter
Enasidenib	Solute carrier family 22 member 6	transporter
Enasidenib	Solute carrier organic anion transporter family member 1B1	transporter
Enasidenib	Solute carrier family 22 member 2	transporter
Enasidenib	Solute carrier organic anion transporter family member 1B3	transporter
Enasidenib	Solute carrier family 22 member 8	transporter
Talimogene laherparepvec	Heparan sulfate	target
Talimogene laherparepvec	DNA polymerase catalytic subunit	target
Talimogene laherparepvec	DNA polymerase catalytic subunit	target
Erdafitinib	Cytochrome P450 2C9	enzyme
Erdafitinib	Cytochrome P450 3A4	enzyme
Erdafitinib	Fibroblast growth factor receptor 1	target
Erdafitinib	Fibroblast growth factor receptor 2	target
Erdafitinib	Fibroblast growth factor receptor 3	target
Erdafitinib	Fibroblast growth factor receptor 4	target
Erdafitinib	P-glycoprotein 1	transporter
Erdafitinib	Solute carrier family 22 member 2	transporter
Erdafitinib	RET proto-oncogene	target
Erdafitinib	Macrophage colony-stimulating factor 1 receptor	target
Erdafitinib	Platelet-derived growth factor receptor alpha	target
Erdafitinib	Platelet-derived growth factor receptor beta	target
Erdafitinib	Mast/stem cell growth factor receptor Kit	target
Erdafitinib	Vascular endothelial growth factor receptor 2	target
Apalutamide	Androgen receptor	target
Apalutamide	Cytochrome P450 3A4	enzyme
Apalutamide	Cytochrome P450 2C8	enzyme
Apalutamide	Cytochrome P450 2C19	enzyme
Apalutamide	Cytochrome P450 2C9	enzyme
Apalutamide	P-glycoprotein 1	transporter
Apalutamide	ATP-binding cassette sub-family G member 2	transporter
Apalutamide	Solute carrier organic anion transporter family member 1B1	transporter
Apalutamide	Solute carrier family 22 member 2	transporter
Apalutamide	Solute carrier family 22 member 8	transporter
Apalutamide	Multidrug and toxin extrusion protein 2	transporter
Apalutamide	GABA(A) Receptor	target
Apalutamide	Multidrug and toxin extrusion protein 1	transporter
Alpelisib	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform	target
Alpelisib	Cytochrome P450 3A4	enzyme
Alpelisib	Cytochrome P450 2C9	enzyme
Alpelisib	Cytochrome P450 2C8	enzyme
Alpelisib	Cytochrome P450 2C19	enzyme
Alpelisib	ATP-binding cassette sub-family G member 2	transporter
Alpelisib	P-glycoprotein 1	transporter
Tubercidin	Purine nucleoside phosphorylase DeoD-type	target
Trimetrexate	Dihydrofolate reductase	target
Trimetrexate	Folate transporter 1	transporter
Epothilone D	Tubulin alpha-3C/D chain	target
Epothilone D	Tubulin beta chain	target
Epothilone D	Tubulin beta-1 chain	target
Epothilone D	Tubulin beta-4B chain	target
Epothilone D	Tubulin beta-4A chain	target
Epothilone D	Tubulin alpha-4A chain	target
Epothilone D	Tubulin beta-3 chain	target
Epothilone D	Tubulin alpha-1C chain	target
Epothilone D	Tubulin alpha-8 chain	target
Epothilone D	Tubulin alpha-1B chain	target
Epothilone D	Tubulin alpha-1A chain	target
Epothilone D	Cytochrome P450 3A4	enzyme
Monastrol	Kinesin-like protein KIF11	target
Galiximab	T-lymphocyte activation antigen CD80	target
Epratuzumab	B-cell receptor CD22	target
Oregovomab	Mucin-16	target
Banoxantrone	DNA topoisomerase 2-alpha	target
Banoxantrone	Cytochrome P450 3A4	enzyme
Banoxantrone	Cytochrome P450 1A1	enzyme
Banoxantrone	Cytochrome P450 2B6	enzyme
Labetuzumab	Carcinoembryonic antigen-related cell adhesion molecule 5	target
Rindopepimut	Epidermal growth factor receptor	target
Pelitinib	Epidermal growth factor receptor	target
Farletuzumab	Folate receptor alpha	target
CT-011	Programmed cell death protein 1	target
Glembatumumab vedotin	Transmembrane glycoprotein NMB	target
AV-412	Epidermal growth factor receptor	target
AV-412	Receptor tyrosine-protein kinase erbB-2	target
Filanesib	Kinesin-like protein KIF11	target
Atrasentan	Endothelin-1 receptor	target
Indisulam	Cytochrome P450 2C9	enzyme
Indisulam	Cytochrome P450 3A4	enzyme
Indisulam	Cytochrome P450 2E1	enzyme
Indisulam	Cytochrome P450 2D6	enzyme
Finafloxacin	DNA gyrase subunit A	target
Finafloxacin	DNA topoisomerase 4 subunit A	target
Finafloxacin	DNA topoisomerase 2-alpha	target
Artesunate	Malaria protein EXP-1	target
Artesunate	Cytochrome P450 2A6	enzyme
Artesunate	UDP-glucuronosyltransferase 2B7	enzyme
Artesunate	UDP-glucuronosyltransferase 1-9	enzyme
Artesunate	ATP-binding cassette sub-family G member 2	transporter
Artesunate	P-glycoprotein 1	transporter
Artesunate	Solute carrier organic anion transporter family member 1B1	transporter
Artesunate	Solute carrier family 22 member 8	transporter
Artesunate	Serum albumin	carrier
Silibinin	Solute carrier family 22 member 6	transporter
Silibinin	UDP-glucuronosyltransferase 1-1	enzyme
Silibinin	Solute carrier organic anion transporter family member 1B1	transporter
Silibinin	Solute carrier organic anion transporter family member 1B3	transporter
Silibinin	Solute carrier organic anion transporter family member 2B1	transporter
Tesevatinib	Pro-epidermal growth factor	target
Tesevatinib	Ephrin type-B receptor 4	target
Tesevatinib	Receptor tyrosine-protein kinase erbB-2	target
Lorvotuzumab mertansine	Cytochrome P450 3A4	enzyme
Zalutumumab	Epidermal growth factor receptor	target
Sagopilone	Cytochrome P450 3A4	enzyme
Dacetuzumab	Tumor necrosis factor receptor superfamily member 5	target
Ivosidenib	Isocitrate dehydrogenase [NADP] cytoplasmic	target
Ivosidenib	Cytochrome P450 3A4	enzyme
Ivosidenib	Cytochrome P450 2B6	enzyme
Ivosidenib	Cytochrome P450 2C9	enzyme
Ivosidenib	Cytochrome P450 2C8	enzyme
Ivosidenib	Solute carrier family 22 member 8	transporter
Ivosidenib	P-glycoprotein 1	transporter
Cemiplimab	Programmed cell death protein 1	target
Zanubrutinib	Cytochrome P450 3A4	enzyme
Zanubrutinib	P-glycoprotein 1	transporter
Zanubrutinib	Cytochrome P450 2B6	enzyme
Zanubrutinib	Tyrosine-protein kinase BTK	target
Zanubrutinib	Epidermal growth factor receptor	target
Zanubrutinib	Receptor tyrosine-protein kinase erbB-2	target
Zanubrutinib	Receptor tyrosine-protein kinase erbB-4	target
Zanubrutinib	Tyrosine-protein kinase ITK/TSK	target
Zanubrutinib	Cytoplasmic tyrosine-protein kinase BMX	target
Zanubrutinib	Tyrosine-protein kinase JAK2	target
Zanubrutinib	Tyrosine-protein kinase Tec	target
Zanubrutinib	Tyrosine-protein kinase Blk	target
Zanubrutinib	Tyrosine-protein kinase JAK3	target
Zanubrutinib	Protein-tyrosine kinase 6	target
Zanubrutinib	Tyrosine-protein kinase Fgr	target
Zanubrutinib	Tyrosine-protein kinase FRK	target
Zanubrutinib	Tyrosine-protein kinase Lck	target
Zanubrutinib	Tyrosine-protein kinase TXK	target
Zanubrutinib	Cytochrome P450 3A Subfamily	enzyme
Tallimustine	DNA	target
Pexidartinib	Cytochrome P450 3A4	enzyme
Pexidartinib	UDP-glucuronosyltransferase 1-4	enzyme
Pexidartinib	Macrophage colony-stimulating factor 1 receptor	target
Pexidartinib	Cytochrome P450 2B6	enzyme
Pexidartinib	Cytochrome P450 2C9	enzyme
Pexidartinib	UDP-glucuronosyltransferase 1-1	enzyme
Pexidartinib	Multidrug and toxin extrusion protein 1	transporter
Pexidartinib	Multidrug and toxin extrusion protein 2	transporter
Pexidartinib	Solute carrier organic anion transporter family member 1B1	transporter
Pexidartinib	Solute carrier organic anion transporter family member 1B3	transporter
Pexidartinib	Solute carrier organic anion transporter family member 2B1	transporter
Pexidartinib	Serum albumin	carrier
Pexidartinib	Alpha-1-acid glycoprotein 1	carrier
Pexidartinib	Mast/stem cell growth factor receptor Kit	target
Pexidartinib	Receptor-type tyrosine-protein kinase FLT3	target
Pexidartinib	Platelet-derived growth factor receptor beta	target
Entrectinib	Cytochrome P450 3A4	enzyme
Entrectinib	P-glycoprotein 1	transporter
Entrectinib	High affinity nerve growth factor receptor	target
Entrectinib	BDNF/NT-3 growth factors receptor	target
Entrectinib	NT-3 growth factor receptor	target
Entrectinib	Proto-oncogene tyrosine-protein kinase ROS	target
Entrectinib	Tyrosine-protein kinase JAK2	target
Entrectinib	Activated CDC42 kinase 1	target
Larotrectinib	Cytochrome P450 3A4	enzyme
Larotrectinib	High affinity nerve growth factor receptor	target
Larotrectinib	BDNF/NT-3 growth factors receptor	target
Larotrectinib	NT-3 growth factor receptor	target
Larotrectinib	P-glycoprotein 1	transporter
Larotrectinib	ATP-binding cassette sub-family G member 2	transporter
Acalabrutinib	Tyrosine-protein kinase BTK	target
Acalabrutinib	Cytochrome P450 3A4	enzyme
Acalabrutinib	Cytochrome P450 3A5	enzyme
Acalabrutinib	Cytochrome P450 3A Subfamily	enzyme
Acalabrutinib	Serum albumin	carrier
Acalabrutinib	alpha1-acid glycoprotein	carrier
4-(dimethylamino)-N-[7-(hydroxyamino)-7-oxoheptyl]benzamide	Histone deacetylase 8	target
Padeliporfin	Solute carrier organic anion transporter family member 1B1	transporter
Padeliporfin	Solute carrier organic anion transporter family member 1B3	transporter
Padeliporfin	Serum albumin	carrier
Ursolic acid	GTPase HRas	target
Ursolic acid	Neutrophil elastase	target
Volasertib	Serine/threonine-protein kinase PLK1	target
MIV-711	Cathepsin K	target
Axicabtagene ciloleucel	B-lymphocyte antigen CD19	target
Bropirimine	Dihydroneopterin aldolase	target
Lexacalcitol	Vitamin D3 receptor	target
Trichostatin A	Histone deacetylase 8	target
Trichostatin A	Acetoin utilization protein	target
Trichostatin A	Histone deacetylase 7	target
Trichostatin A	Caspase-8	target
Trichostatin A	Prostaglandin E2 Receptors	target
Trichostatin A	Tumor necrosis factor	target
alpha,beta-Methyleneadenosine 5'-triphosphate	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase	target
alpha,beta-Methyleneadenosine 5'-triphosphate	Pantothenate synthetase	target
alpha,beta-Methyleneadenosine 5'-triphosphate	NH(3)-dependent NAD(+) synthetase	target
alpha,beta-Methyleneadenosine 5'-triphosphate	Nicotinamide mononucleotide adenylyltransferase 3	target
alpha,beta-Methyleneadenosine 5'-triphosphate	Adenylate cyclase	target
alpha,beta-Methyleneadenosine 5'-triphosphate	NTPase P4	target
alpha,beta-Methyleneadenosine 5'-triphosphate	Probable lignin peroxidase LipJ	target
alpha,beta-Methyleneadenosine 5'-triphosphate	Carbapenam-3-carboxylate synthase	target
5'-S-methyl-5'-thioadenosine	Modification methylase RsrI	target
5'-S-methyl-5'-thioadenosine	S-methyl-5'-thioadenosine phosphorylase	target
Isatuximab	ADP-ribosyl cyclase 1	target
Pemigatinib	Cytochrome P450 3A4	enzyme
Pemigatinib	Fibroblast growth factor receptor 1	target
Pemigatinib	Fibroblast growth factor receptor 2	target
Pemigatinib	Fibroblast growth factor receptor 3	target
Pemigatinib	Fibroblast growth factor receptor 4	target
Pemigatinib	P-glycoprotein 1	transporter
Pemigatinib	ATP-binding cassette sub-family G member 2	transporter
Pemigatinib	Solute carrier family 22 member 2	transporter
Pemigatinib	Multidrug and toxin extrusion protein 1	transporter
Darolutamide	Cytochrome P450 3A4	enzyme
Darolutamide	UDP-glucuronosyltransferase 1-9	enzyme
Darolutamide	Androgen receptor	target
Darolutamide	ATP-binding cassette sub-family G member 2	transporter
Darolutamide	P-glycoprotein 1	transporter
Darolutamide	Serum albumin	carrier
Darolutamide	Progesterone receptor	target
Darolutamide	Solute carrier organic anion transporter family member 1B1	transporter
Darolutamide	Solute carrier organic anion transporter family member 1B3	transporter
Capmatinib	Cytochrome P450 3A4	enzyme
Capmatinib	Aldehyde oxidase	enzyme
Capmatinib	Hepatocyte growth factor receptor	target
Capmatinib	P-glycoprotein 1	transporter
Capmatinib	Multidrug and toxin extrusion protein 1	transporter
Capmatinib	Multidrug and toxin extrusion protein 2	transporter
Capmatinib	Cytochrome P450 1A2	enzyme
Capmatinib	ATP-binding cassette sub-family G member 2	transporter
Selpercatinib	Proto-oncogene tyrosine-protein kinase receptor Ret	target
Selpercatinib	Vascular endothelial growth factor receptor 1	target
Selpercatinib	Vascular endothelial growth factor receptor 3	target
Selpercatinib	Fibroblast growth factor receptor 1	target
Selpercatinib	Fibroblast growth factor receptor 2	target
Selpercatinib	Fibroblast growth factor receptor 3	target
Selpercatinib	Cytochrome P450 3A4	enzyme
Selpercatinib	Cytochrome P450 2C8	enzyme
Selpercatinib	Cytochrome P450 3A Subfamily	enzyme
Selpercatinib	P-glycoprotein 1	transporter
Selpercatinib	ATP-binding cassette sub-family G member 2	transporter
Selpercatinib	Multidrug and toxin extrusion protein 1	transporter
Incadronic acid	Farnesyl pyrophosphate synthase	target
Incadronic acid	Caspase-3	target
Incadronic acid	Caspase-4	target
Incadronic acid	Caspase-7	target
Brexucabtagene autoleucel	B-lymphocyte antigen CD19	target
Selinexor	Cytochrome P450 3A4	enzyme
Selinexor	Solute carrier organic anion transporter family member 1B3	transporter
Selinexor	Exportin-1	target
Fedratinib	P-glycoprotein 1	transporter
Fedratinib	ATP-binding cassette sub-family G member 2	transporter
Fedratinib	Solute carrier organic anion transporter family member 1B1	transporter
Fedratinib	Solute carrier organic anion transporter family member 1B3	transporter
Fedratinib	POU domain, class 2, transcription factor 2	transporter
Fedratinib	Multidrug and toxin extrusion protein 1	transporter
Fedratinib	Multidrug and toxin extrusion protein 2	transporter
Fedratinib	Cytochrome P450 3A4	enzyme
Fedratinib	Cytochrome P450 2C19	enzyme
Fedratinib	Dimethylaniline monooxygenase [N-oxide-forming] 3	enzyme
Fedratinib	Tyrosine-protein kinase JAK2	target
Fedratinib	Receptor-type tyrosine-protein kinase FLT3	target
Fedratinib	Tyrosine-protein kinase JAK1	target
Fedratinib	Cytochrome P450 2D6	enzyme
Quizartinib	Receptor-type tyrosine-protein kinase FLT3	target
Pralsetinib	Proto-oncogene tyrosine-protein kinase receptor Ret	target
Pralsetinib	Epithelial discoidin domain-containing receptor 1	target
Pralsetinib	NT-3 growth factor receptor	target
Pralsetinib	Receptor-type tyrosine-protein kinase FLT3	target
Pralsetinib	Tyrosine-protein kinase JAK1	target
Pralsetinib	Tyrosine-protein kinase JAK2	target
Pralsetinib	High affinity nerve growth factor receptor	target
Pralsetinib	Vascular endothelial growth factor receptor 2	target
Pralsetinib	Platelet-derived growth factor receptor beta	target
Pralsetinib	Fibroblast growth factor receptor 1	target
Pralsetinib	Fibroblast growth factor receptor 2	target
Pralsetinib	Cytochrome P450 3A4	enzyme
Pralsetinib	Cytochrome P450 3A5	enzyme
Pralsetinib	Cytochrome P450 2D6	enzyme
Pralsetinib	Cytochrome P450 1A2	enzyme
Pralsetinib	Cytochrome P450 2C8	enzyme
Pralsetinib	Cytochrome P450 2C9	enzyme
Pralsetinib	P-glycoprotein 1	transporter
Pralsetinib	ATP-binding cassette sub-family G member 2	transporter
Pralsetinib	Solute carrier organic anion transporter family member 1B1	transporter
Pralsetinib	Solute carrier organic anion transporter family member 1B3	transporter
Pralsetinib	Solute carrier family 22 member 6	transporter
Pralsetinib	Multidrug and toxin extrusion protein 1	transporter
Pralsetinib	Multidrug and toxin extrusion protein 2	transporter
Pralsetinib	Bile salt export pump	transporter
Tucatinib	Receptor tyrosine-protein kinase erbB-2	target
Tucatinib	ATP-binding cassette sub-family G member 2	transporter
Tucatinib	P-glycoprotein 1	transporter
Tucatinib	Solute carrier family 22 member 2	transporter
Tucatinib	Multidrug and toxin extrusion protein 1	transporter
Tucatinib	Multidrug and toxin extrusion protein 2	transporter
Tucatinib	Cytochrome P450 2C8	enzyme
Tucatinib	Cytochrome P450 3A Subfamily	enzyme
Tucatinib	Receptor tyrosine-protein kinase erbB-2	enzyme
Tucatinib	Receptor tyrosine-protein kinase erbB-3	target
Tirbanibulin	Proto-oncogene tyrosine-protein kinase Src	target
Tirbanibulin	Tubulin beta chain	target
Tirbanibulin	Cytochrome P450 3A4	enzyme
Tirbanibulin	Cytochrome P450 2C8	enzyme
Tirbanibulin	Cytochrome P450 1A2	enzyme
Tirbanibulin	Cytochrome P450 2B6	enzyme
Tirbanibulin	Cytochrome P450 2C9	enzyme
Tirbanibulin	Cytochrome P450 2C19	enzyme
Tirbanibulin	Cytochrome P450 2D6	enzyme
Tirbanibulin	Multidrug and toxin extrusion protein 1	transporter
Tirbanibulin	Multidrug and toxin extrusion protein 2	transporter
Tirbanibulin	Solute carrier organic anion transporter family member 1B1	transporter
Tirbanibulin	Solute carrier organic anion transporter family member 1B3	transporter
Tirbanibulin	Solute carrier family 22 member 1	transporter
Tirbanibulin	Solute carrier family 22 member 2	transporter
Polatuzumab vedotin	Cytochrome P450 3A4	enzyme
Polatuzumab vedotin	B-cell antigen receptor complex-associated protein beta chain	target
Polatuzumab vedotin	P-glycoprotein 1	transporter
Polatuzumab vedotin	Cytochrome P450 3A5	enzyme
Tepotinib	P-glycoprotein 1	transporter
Tepotinib	Cytochrome P450 3A4	enzyme
Tepotinib	Cytochrome P450 2C8	enzyme
Tepotinib	ATP-binding cassette sub-family G member 2	transporter
Tepotinib	Hepatocyte growth factor receptor	target
Tepotinib	Nischarin	target
Tepotinib	Melatonin receptor type 1B	target
Tepotinib	Serum albumin	carrier
Tepotinib	Alpha-1-acid glycoprotein 1	carrier
Tepotinib	Solute carrier family 22 member 1	transporter
Tepotinib	Solute carrier family 22 member 2	transporter
Tepotinib	Multidrug and toxin extrusion protein 1	transporter
Tepotinib	Multidrug and toxin extrusion protein 2	transporter
Tepotinib	Bile salt export pump	transporter
Tepotinib	Cytochrome P450 2C9	enzyme
Lisocabtagene maraleucel	B-lymphocyte antigen CD19	target
Ripretinib	Mast/stem cell growth factor receptor Kit	target
Ripretinib	Platelet-derived growth factor receptor beta	target
Ripretinib	Angiopoietin-1 receptor	target
Ripretinib	Vascular endothelial growth factor receptor 2	target
Ripretinib	Serine/threonine-protein kinase B-raf	target
Ripretinib	Platelet-derived growth factor receptor alpha	target
Ripretinib	Cytochrome P450 2C8	enzyme
Ripretinib	Platelet-derived growth factor receptor alpha	enzyme
Ripretinib	Serum albumin	carrier
Ripretinib	alpha1-acid glycoprotein	carrier
Ripretinib	P-glycoprotein 1	transporter
Ripretinib	ATP-binding cassette sub-family G member 2	transporter
Ripretinib	Multidrug and toxin extrusion protein 1	transporter
Ripretinib	Cytochrome P450 3A4	enzyme
Ripretinib	Cytochrome P450 2D6	enzyme
Ripretinib	Cytochrome P450 2E1	enzyme
Umbralisib	P-glycoprotein 1	transporter
Umbralisib	Cytochrome P450 2C9	enzyme
Umbralisib	Cytochrome P450 1A2	enzyme
Umbralisib	Cytochrome P450 3A4	enzyme
Umbralisib	Casein kinase I isoform epsilon	target
Umbralisib	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform	target
Umbralisib	Tyrosine-protein kinase ABL1	enzyme
Umbralisib	Tyrosine-protein kinase ABL1	target
Idecabtagene vicleucel	Tumor necrosis factor receptor superfamily member 17	target
Dostarlimab	Programmed cell death protein 1	target
Sotorasib	GTPase KRas	target
Sotorasib	Cytochrome P450 3A Subfamily	enzyme
Sotorasib	Cytochrome P450 2C8	enzyme
Sotorasib	Cytochrome P450 2C9	enzyme
Sotorasib	Cytochrome P450 2B6	enzyme
Sotorasib	ATP-binding cassette sub-family G member 2	transporter
Sotorasib	P-glycoprotein 1	transporter
Tisagenlecleucel	B-lymphocyte antigen CD19	target
Trastuzumab deruxtecan	P-glycoprotein 1	transporter
Trastuzumab deruxtecan	High affinity immunoglobulin gamma Fc receptor I	target
Trastuzumab deruxtecan	DNA topoisomerase 1	target
Trastuzumab deruxtecan	Lysosomal alpha-glucosidase	enzyme
Trastuzumab deruxtecan	DNA topoisomerase 1	enzyme
Trastuzumab deruxtecan	Cathepsin B	enzyme
Trastuzumab deruxtecan	Cathepsin L1	enzyme
Trastuzumab deruxtecan	Cytochrome P450 3A4	enzyme
Trastuzumab deruxtecan	Solute carrier organic anion transporter family member 1B1	transporter
Trastuzumab deruxtecan	Solute carrier organic anion transporter family member 1B3	transporter
Trastuzumab deruxtecan	Multidrug and toxin extrusion protein 2	transporter
Trastuzumab deruxtecan	Multidrug resistance-associated protein 1	transporter
Trastuzumab deruxtecan	ATP-binding cassette sub-family G member 2	transporter
Belzutifan	Endothelial PAS domain-containing protein 1	target
Belzutifan	UDP-glucuronosyltransferase 2B17	enzyme
Belzutifan	Cytochrome P450 2C19	enzyme
Belzutifan	Cytochrome P450 3A4	enzyme
Belzutifan	P-glycoprotein 1	transporter
Belzutifan	Solute carrier organic anion transporter family member 1B1	transporter
Belzutifan	Solute carrier organic anion transporter family member 1B3	transporter
Belzutifan	Multidrug and toxin extrusion protein 2	transporter
Tisotumab vedotin	Cytochrome P450 3A4	enzyme
Tisotumab vedotin	Tissue factor	target
Tisotumab vedotin	P-glycoprotein 1	transporter
Sacituzumab govitecan	Tumor-associated calcium signal transducer 2	target
Sacituzumab govitecan	DNA topoisomerase 1	target
Sacituzumab govitecan	Far upstream element-binding protein 1	target
Sacituzumab govitecan	UDP-glucuronosyltransferase 1-1	enzyme
Margetuximab	Receptor tyrosine-protein kinase erbB-2	target
Interferon alfa-2a	Interferon alpha/beta receptor 1	target
Interferon alfa-2a	Interferon alpha/beta receptor 2	target
Interferon alfa-2a	Cytochrome P450 1A2	enzyme
Ulocuplumab	C-X-C chemokine receptor type 4	target
Futibatinib	Cytochrome P450 3A4	enzyme
Futibatinib	P-glycoprotein 1	transporter
Futibatinib	ATP-binding cassette sub-family G member 2	transporter
Futibatinib	Serum albumin	carrier
Futibatinib	Alpha-1-acid glycoprotein 1	carrier
Futibatinib	Cytochrome P450 2C9	enzyme
Futibatinib	Cytochrome P450 2D6	enzyme
Futibatinib	Fibroblast growth factor receptor 1	target
Futibatinib	Fibroblast growth factor receptor 2	target
Futibatinib	Fibroblast growth factor receptor 3	target
Futibatinib	Fibroblast growth factor receptor 4	target
Adagrasib	GTPase KRas	target
Adagrasib	Cytochrome P450 3A4	enzyme
Adagrasib	Cytochrome P450 2C8	enzyme
Adagrasib	Cytochrome P450 1A2	enzyme
Adagrasib	Cytochrome P450 2B6	enzyme
Adagrasib	Cytochrome P450 2C9	enzyme
Adagrasib	Cytochrome P450 2D6	enzyme
Adagrasib	P-glycoprotein 1	transporter
Spartalizumab	Programmed cell death protein 1	target
Tislelizumab	Programmed cell death protein 1	target
Loncastuximab tesirine	B-lymphocyte antigen CD19	target
Loncastuximab tesirine	P-glycoprotein 1	transporter
Loncastuximab tesirine	Cytochrome P450 3A4	enzyme
Loncastuximab tesirine	Cytochrome P450 3A5	enzyme
Amivantamab	Epidermal growth factor receptor	target
Amivantamab	Hepatocyte growth factor receptor	target
Amivantamab	Low affinity immunoglobulin gamma Fc region receptor III-A	target
Deacetoxyvinzolidine	Calmodulin	target
Tebentafusp	Melanocyte protein PMEL	target
Lurbinectedin	Cytochrome P450 3A4	enzyme
Lurbinectedin	DNA	target
Lurbinectedin	Serum albumin	carrier
Lurbinectedin	Alpha-1-acid glycoprotein 1	carrier
Lurbinectedin	P-glycoprotein 1	transporter
Lurbinectedin	Solute carrier organic anion transporter family member 1B1	transporter
Lurbinectedin	Solute carrier organic anion transporter family member 1B3	transporter
Lurbinectedin	Solute carrier family 22 member 1	transporter
Enfortumab vedotin	Cytochrome P450 3A4	enzyme
Enfortumab vedotin	Nectin-4	target
Enfortumab vedotin	P-glycoprotein 1	transporter
Mosunetuzumab	B-lymphocyte antigen CD20	target
Mosunetuzumab	T-cell surface glycoprotein CD3 epsilon chain	target
Oportuzumab monatox	Epithelial cell adhesion molecule	target
Selumetinib	Dual specificity mitogen-activated protein kinase kinase 1	target
Selumetinib	Dual specificity mitogen-activated protein kinase kinase 2	target
Selumetinib	Serum albumin	carrier
Selumetinib	alpha1-acid glycoprotein	carrier
Selumetinib	P-glycoprotein 1	transporter
Selumetinib	ATP-binding cassette sub-family G member 2	transporter
Selumetinib	Cytochrome P450 2C19	enzyme
Selumetinib	UDP-glucuronosyltransferase 1-1	enzyme
Selumetinib	Cytochrome P450 2C9	enzyme
Selumetinib	Cytochrome P450 3A4	enzyme
Selumetinib	Cytochrome P450 1A2	enzyme
Selumetinib	Cytochrome P450 2C8	enzyme
Selumetinib	UDP-glucuronosyltransferase 1-3	enzyme
Selumetinib	Cytochrome P450 2E1	enzyme
Selumetinib	Cytochrome P450 3A5	enzyme
Pacritinib	Cytochrome P450 3A4	enzyme
Pacritinib	Cytochrome P450 1A2	enzyme
Pacritinib	Tyrosine-protein kinase JAK2	target
Pacritinib	Receptor-type tyrosine-protein kinase FLT3	target
Pacritinib	P-glycoprotein 1	transporter
Pacritinib	ATP-binding cassette sub-family G member 2	transporter
Pacritinib	Solute carrier family 22 member 1	transporter
Pacritinib	Cytochrome P450 2C19	enzyme
Pacritinib	Solute carrier family 22 member 2	transporter
Duvelisib	Cytochrome P450 3A4	enzyme
Duvelisib	P-glycoprotein 1	transporter
Duvelisib	ATP-binding cassette sub-family G member 2	transporter
Duvelisib	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform	target
Duvelisib	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform	target
Asciminib	Cytochrome P450 3A4	enzyme
Asciminib	UDP-glucuronosyltransferase 2B7	enzyme
Asciminib	UDP-glucuronosyltransferase 2B17	enzyme
Asciminib	Tyrosine-protein kinase ABL1	target
Asciminib	ATP-binding cassette sub-family G member 2	transporter
Asciminib	UDP-glucuronosyltransferase 1-1	enzyme
Asciminib	Cytochrome P450 2C19	enzyme
Asciminib	P-glycoprotein 1	transporter
Asciminib	Solute carrier organic anion transporter family member 1B1	transporter
Asciminib	Solute carrier organic anion transporter family member 1B3	transporter
Asciminib	Solute carrier family 22 member 1	transporter
Asciminib	Cytochrome P450 2C9	enzyme
Tazemetostat	Histone-lysine N-methyltransferase EZH2	target
Tazemetostat	P-glycoprotein 1	transporter
Tazemetostat	Multidrug and toxin extrusion protein 1	transporter
Tazemetostat	Multidrug and toxin extrusion protein 2	transporter
Tazemetostat	Cytochrome P450 3A Subfamily	enzyme
Tazemetostat	Histone-lysine N-methyltransferase EZH1	target
Tazemetostat	ATP-binding cassette sub-family G member 2	transporter
Tazemetostat	Cytochrome P450 3A4	enzyme
Tafasitamab	B-lymphocyte antigen CD19	target
Avapritinib	Platelet derived growth factor receptor alpha	target
Avapritinib	Mast/stem cell growth factor receptor Kit	target
Avapritinib	P-glycoprotein 1	transporter
Avapritinib	ATP-binding cassette sub-family G member 2	transporter
Avapritinib	Cytochrome P450 3A4	enzyme
Avapritinib	Cytochrome P450 2C9	enzyme
Avapritinib	Bile salt export pump	transporter
Avapritinib	Multidrug and toxin extrusion protein 1	transporter
Avapritinib	Multidrug and toxin extrusion protein 2	transporter
Belantamab mafodotin	Solute carrier organic anion transporter family member 1B1	transporter
Belantamab mafodotin	Solute carrier organic anion transporter family member 1B3	transporter
Belantamab mafodotin	Multidrug resistance-associated protein 1	transporter
Belantamab mafodotin	Canalicular multispecific organic anion transporter 1	transporter
Belantamab mafodotin	Canalicular multispecific organic anion transporter 2	transporter
Belantamab mafodotin	Bile salt export pump	transporter
Belantamab mafodotin	P-glycoprotein 1	transporter
Belantamab mafodotin	Tumor necrosis factor receptor superfamily member 17	target
Retifanlimab	Programmed cell death protein 1	target
Melphalan flufenamide	Aminopeptidase N	enzyme
Melphalan flufenamide	DNA	target
Prolgolimab	Programmed cell death protein 1	target
Mirvetuximab soravtansine	Cytochrome P450 3A4	enzyme
Mirvetuximab soravtansine	Folate receptor alpha	target
Mirvetuximab soravtansine	P-glycoprotein 1	transporter
Olutasidenib	Isocitrate dehydrogenase [NADP] cytoplasmic	target
Olutasidenib	Cytochrome P450 3A4	enzyme
Olutasidenib	Cytochrome P450 2C8	enzyme
Olutasidenib	Cytochrome P450 2C9	enzyme
Olutasidenib	Cytochrome P450 1A2	enzyme
Olutasidenib	Cytochrome P450 2C19	enzyme
Olutasidenib	P-glycoprotein 1	transporter
Olutasidenib	ATP-binding cassette sub-family G member 2	transporter
Olutasidenib	Solute carrier organic anion transporter family member 1B1	transporter
Olutasidenib	Solute carrier organic anion transporter family member 1B3	transporter
Olutasidenib	Solute carrier family 22 member 8	transporter
Olutasidenib	Solute carrier family 22 member 2	transporter
Olutasidenib	Multidrug and toxin extrusion protein 1	transporter
Olutasidenib	Multidrug and toxin extrusion protein 2	transporter
Olutasidenib	Cytochrome P450 2B6	enzyme