Endodeoxyribonucleases

DBCAT002871Pharmacologic class

A group of enzymes catalyzing the endonucleolytic cleavage of DNA. They include members of EC 3.1.21.-, EC 3.1.22.-, EC 3.1.23.- (DNA RESTRICTION ENZYMES), EC 3.1.24.- (DNA RESTRICTION ENZYMES), and EC 3.1.25.-. A DrugBank category of 4 drugs. 1 of them is approved.

Drugs: Deoxyribonuclease I
Dimericine
Dornase alfa
Streptodornase

What you can answer from here — as of November 01, 2016

4DrugsEach linked to its full drug card

Listed above

2Drug targetsEvery drug–target pair in the class, with bond type

11Marketed productsAcross the regions we cover, with dosage forms and routes

1Route of administrationHow the drugs in this class are given

Which targets do Endodeoxyribonucleases share, and which companies have late-stage candidates in this class?

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