ADP Ribose Transferases
- Name
- ADP Ribose Transferases
- Accession Number
- DBCAT002875
- Description
Enzymes that transfer the ADP-RIBOSE group of NAD or NADP to proteins or other small molecules. Transfer of ADP-ribose to water (i.e., hydrolysis) is catalyzed by the NADASES. The mono(ADP-ribose)transferases transfer a single ADP-ribose. POLY(ADP-RIBOSE) POLYMERASES transfer multiple units of ADP-ribose to protein targets, building POLY ADENOSINE DIPHOSPHATE RIBOSE in linear or branched chains.
- Drugs
Drug Drug Description Denileukin diftitox A recombinant cytotoxic protein based on a combination of diphtheria toxin fragments and interleukin-2 used to treat cutaneous T-cell lymphoma by targeting the interleukin-2 receptor. Recombinant Cholera Toxin B Subunit Recombinant Cholera Toxin B Subunit is an ingredient in the EMA-authorised product Dukoral. SOT-107 Investigated for use/treatment in brain cancer. - Drugs & Drug Targets