- Accession Number
A fibrous protein complex that consists of proteins folded into a specific cross beta-pleated sheet structure. This fibrillar structure has been found as an alternative folding pattern for a variety of functional proteins. Deposits of amyloid in the form of AMYLOID PLAQUES are associated with a variety of degenerative diseases. The amyloid structure has also been found in a number of functional proteins that are unrelated to disease.
Drug Drug Description Pramlintide An amylin analog used for the management of type 1 and type 2 diabetes mellitus as an adjunct to preprandial insulin therapy in patients without adequate glycemic control of insulin therapy. PRM-151 PRM-151 is under investigation in clinical trial NCT01981850 (A Phase 2 Study Of PRM-151 In Subjects With Myelofibrosis). Amlintide A medication used in combination with corticosteroids for the treatment of hemorrhoids.
- Drugs & Drug Targets
Drug Target Type Pramlintide Receptor activity-modifying protein 1 target Pramlintide Receptor activity-modifying protein 2 target Pramlintide Receptor activity-modifying protein 3 target Pramlintide Calcitonin receptor target