- Mollusk Venoms
- Accession Number
Venoms from mollusks, including CONUS and OCTOPUS species. The venoms contain proteins, enzymes, choline derivatives, slow-reacting substances, and several characterized polypeptide toxins that affect the nervous system. Mollusk venoms include cephalotoxin, venerupin, maculotoxin, surugatoxin, conotoxins, and murexine.
Drug Drug Description Ziconotide An N-type calcium channel antagonist used to manage patients with severe chronic pain who cannot tolerate, or who have not responded adequately to other treatments such as intrathecal morphine and systemic analgesics. alpha-Conotoxin VC 1.1 Investigated for use/treatment in pain (acute or chronic).
- Drugs & Drug Targets
Drug Target Type Ziconotide Voltage-dependent N-type calcium channel subunit alpha-1B target Ziconotide Voltage-dependent P/Q-type calcium channel subunit alpha-1A target