Gonyautoxin II

DB19186InvestigationalSmall molecule

Gonyautoxin II is under investigation in clinical trial NCT04799041 (Gonyautoxin 2/3 in the Treatment of Acute Back Pain: A Clinical Proof-of-concept Study).

Chemical structure of Gonyautoxin II
Formula / weight
C10H17N7O8S · 395.35 g/mol (avg)
Also known as
1h,10h-pyrrolo(1,2-c)purine-9,10,10-triol, 2,6-diamino-4-(((aminocarbonyl)oxy)methyl)-3a,4,8,9-tetrahydro-, 9-(hydrogen sulfate), (3as-(3a.alpha.,4.alpha.,9.beta.,10ar*))- 11.alpha.-hydroxysaxitoxin 11-sulfate · Gonyautoxin 2 · Gonyautoxin iim
Code names
GTX2 · GTX II

Resolves to

Structure
InChIKeyARSXTTJGWGCRRR-XXKOCQOQSA-NSMILES[H][C@@]12NC(=N)N[C@]11N(C[C@@H](OS(O)(=O)=O)C1(O)O)C(=N)N[C@H]2COC(N)=O

What you can answer from here — as of July 09, 2026

1Protein targetEach mapped to UniProt, with action and pharmacological action
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2Clinical trialsPhase, status and sponsor resolved per trial
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2+ReferencesStructured and connected to the statements they support
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Which companies are running trials of Gonyautoxin II, in which indications and phases, and which of those programs are still active?

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