Glucosylceramide Synthase Inhibitor
- Name
- Glucosylceramide Synthase Inhibitor
- Accession Number
- DBCAT003346
- Description
Not Available
- Drugs
Drug Drug Description Miglustat A glucosylceramide synthase inhibitor used for the management of mild to moderate type I Gaucher disease for patients who are not candidates for whole enzyme replacement. Eliglustat A glucosylceramide synthase used to treat type 1 Gaucher disease in patients who are CYP2D6 extensive, intermediate, or poor metabolizers. - Drugs & Drug Targets
Drug Target Type Miglustat Ceramide glucosyltransferase target Eliglustat Ceramide glucosyltransferase target Eliglustat Cytochrome P450 2D6 enzyme Eliglustat Cytochrome P450 3A4 enzyme Eliglustat ATP-dependent translocase ABCB1 transporter