Androgen Receptor Inhibitors

All categories
Name
Androgen Receptor Inhibitors
Accession Number
DBCAT003360
Description

Not Available

Drugs
DrugDrug Description
ApalutamideAn androgen receptor inhibitor used to treat non-metastatic castration-resistant and metastatic castration-sensitive prostate cancer.
BicalutamideAn androgen receptor inhibitor used to treat Stage D2 metastatic carcinoma of the prostate.
ClascoteroneAn androgen receptor antagonist used for the topical treatment of acne vulgaris in patients 12 years of age and older.
DarolutamideAn androgen receptor antagonist used for castration-resistant, non-metastatic prostate cancer and metastatic hormone-sensitive prostate cancer.
EnzalutamideA second-generation androgen receptor inhibitor used to treat castration-resistant prostate cancer and metastatic castration-sensitive prostate cancer.
FlutamideAn antiandrogen used for locally confined stage B2-C and D-2 metastatic prostate carcinoma.
NilutamideAn antineoplastic hormone used to treat prostate cancer.
Drugs & Drug Targets
DrugTargetType
ApalutamideAlbumincarrier
ApalutamideMultidrug and toxin extrusion protein 1transporter
ApalutamideGABA(A) Receptortarget
ApalutamideMultidrug and toxin extrusion protein 2transporter
ApalutamideOrganic anion transporter 3transporter
ApalutamideSolute carrier family 22 member 2transporter
ApalutamideSolute carrier organic anion transporter family member 1B1transporter
ApalutamideBroad substrate specificity ATP-binding cassette transporter ABCG2transporter
ApalutamideATP-dependent translocase ABCB1transporter
ApalutamideCytochrome P450 2C9enzyme
ApalutamideCytochrome P450 2C19enzyme
ApalutamideCytochrome P450 2C8enzyme
ApalutamideCytochrome P450 3A4enzyme
ApalutamideAndrogen receptortarget
BicalutamideAndrogen receptortarget
BicalutamideCytochrome P450 3A4enzyme
BicalutamideCytochrome P450 2C19enzyme
BicalutamideCytochrome P450 2C9enzyme
BicalutamideCytochrome P450 2D6enzyme
BicalutamideATP-dependent translocase ABCB1transporter
ClascoteroneCytochrome P450 2B6enzyme
ClascoteroneCytochrome P450 3A4enzyme
ClascoteroneCytochrome P450 2E1enzyme
ClascoteroneCytochrome P450 2D6enzyme
ClascoteroneCytochrome P450 2C19enzyme
ClascoteroneCytochrome P450 2C9enzyme
ClascoteroneCytochrome P450 2C8enzyme
ClascoteroneAndrogen receptortarget
ClascoteroneCytochrome P450 1A2enzyme
DarolutamideSolute carrier organic anion transporter family member 1B3transporter
DarolutamideCytochrome P450 3A4enzyme
DarolutamideUDP-glucuronosyltransferase 1A9enzyme
DarolutamideAndrogen receptortarget
DarolutamideBroad substrate specificity ATP-binding cassette transporter ABCG2transporter
DarolutamideATP-dependent translocase ABCB1transporter
DarolutamideAlbumincarrier
DarolutamideProgesterone receptortarget
DarolutamideSolute carrier organic anion transporter family member 1B1transporter
EnzalutamideATP-dependent translocase ABCB1transporter
EnzalutamideCytochrome P450 3A5enzyme
EnzalutamideCytochrome P450 2B6enzyme
EnzalutamideCytochrome P450 2C19enzyme
EnzalutamideCytochrome P450 2C9enzyme
EnzalutamideAndrogen receptortarget
EnzalutamideCytochrome P450 3A4enzyme
EnzalutamideCytochrome P450 2C8enzyme
EnzalutamideAlbumincarrier
FlutamideMultidrug resistance-associated protein 1transporter
FlutamideNuclear receptor subfamily 1 group I member 2target
FlutamideAryl hydrocarbon receptortarget
FlutamideCytochrome P450 3A5enzyme
FlutamideCytochrome P450 1B1enzyme
FlutamideCytochrome P450 1A1enzyme
FlutamideCytochrome P450 3A4enzyme
FlutamideCytochrome P450 1A2enzyme
FlutamideAndrogen receptortarget
NilutamideNADPH--cytochrome P450 reductaseenzyme
NilutamideCytochrome P450 2C19enzyme
NilutamideAndrogen receptortarget