Potassium Channel Opener

Name
Potassium Channel Opener
Accession Number
DBCAT003451  (DBCAT004293)
Description

Not Available

Drugs
DrugDrug Description
EzogabineAn antiepileptic agent used as an adjuvant treatment of partial-onset seizures.
MinoxidilAn antihypertensive vasodilating agent used for resistant hypertension that is symptomatic or has caused end organ damage.
NicorandilA vasodilatory drug that functions through potassium channels and intracellular cGMP concentrations commonly used to treat angina.
PinacidilPinacidil is a cyanoguanidine drug that acts by opening ATP-sensitive potassium channels, leading to peripheral vasodilatation of arterioles and decreasing peripheral vascular resistance. The above processes result in reduced blood...
DiazoxideA non diuretic benzothiadiazine indicated for the management of hypoglycemia in patients who produce an excess of insulin caused by a variety of conditions.
Drugs & Drug Targets
DrugTargetType
EzogabinePotassium voltage-gated channel subfamily KQT member 2target
EzogabinePotassium voltage-gated channel subfamily KQT member 3target
EzogabinePotassium voltage-gated channel subfamily KQT member 4target
EzogabinePotassium voltage-gated channel subfamily KQT member 5target
EzogabineUDP-glucuronosyltransferase 1-1enzyme
EzogabineUDP-glucuronosyltransferase 1-3enzyme
EzogabineUDP-glucuronosyltransferase 1-4enzyme
EzogabineUDP-glucuronosyltransferase 1-9enzyme
EzogabineArylamine N-acetyltransferase 2enzyme
MinoxidilATP-sensitive inward rectifier potassium channel 1target
MinoxidilProstaglandin G/H synthase 1target
MinoxidilRenintarget
MinoxidilUDP-glucuronosyltransferase 1-1enzyme
NicorandilATP-binding cassette sub-family C member 9target
PinacidilCytochrome P450 3A4enzyme
DiazoxideATP-sensitive inward rectifier potassium channel 11target
DiazoxideSerum albumincarrier
DiazoxideMitochondrial ATP synthase F1 domaintarget