DB06762ApprovedSmall molecule
Pinacidil is a cyanoguanidine drug that acts by opening ATP-sensitive potassium channels, leading to peripheral vasodilatation of arterioles and decreasing peripheral vascular resistance. The above processes result in reduced blood... This drug has been discontinued by the FDA.
- Mechanism
- Curator reviewed
Pharmacologically active on ATP-binding cassette sub-family C member 9, ATP-sensitive inward rectifier potassium channel 11, and ATP-sensitive potassium channel
- Formula / weight
- C13H19N5 · 245.33 g/mol (avg)
- Code names
- P-1134 · S-1230
Resolves to
Clinical / RWD
Structure
InChIKey
IVVNZDGDKPTYHK-UHFFFAOYSA-NSMILESCC(N\C(NC#N)=N\C1=CC=NC=C1)C(C)(C)CTargets
What you can answer from here — as of September 23, 2026
3Protein targetsEach mapped to UniProt, with action and pharmacological actionListed above
Which drugs share a target with Pinacidil, and which of those have an active Phase 3 trial?
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