Interferon-alpha

Name
Interferon-alpha
Accession Number
DBCAT004225
Description

One of the type I interferons produced by peripheral blood leukocytes or lymphoblastoid cells. In addition to antiviral activity, it activates NATURAL KILLER CELLS and B-LYMPHOCYTES, and down-regulates VASCULAR ENDOTHELIAL GROWTH FACTOR expression through PI-3 KINASE and MAPK KINASES signaling pathways.

Drugs
DrugDrug Description
Interferon alfa-n3A purified form of human interferon used to stimulate the innate antiviral response in the treatment of genital warts due to human papilloma virus.
Interferon alfaAn immunomodulator used to treat hepatitis B and C as well as certain types of cancer including cutaneous T-cell lymphoma and renal cell carcinoma.
Peginterferon alfa-2bA purified form of human interferon used to stimulate the innate antiviral response in the treatment of hepatitis B and C, genital warts, and some cancers.
Drugs & Drug Targets
DrugTargetType
Interferon alfa-n3Interferon alpha/beta receptor 1target
Interferon alfa-n3Interferon alpha/beta receptor 2target
Interferon alfa-n3Cytochrome P450 1A2enzyme
Interferon alfaInterferon alpha/beta receptor 1target
Interferon alfaCytochrome P450 1A2enzyme
Peginterferon alfa-2bInterferon alpha/beta receptor 1target
Peginterferon alfa-2bInterferon alpha/beta receptor 2target
Peginterferon alfa-2bCytochrome P450 1A2enzyme
Peginterferon alfa-2bCytochrome P450 2D6enzyme
Peginterferon alfa-2bCytochrome P450 2C9enzyme