Cytochrome P-450 CYP2C18 Substrates with a Narrow Therapeutic Index
- Name
- Cytochrome P-450 CYP2C18 Substrates with a Narrow Therapeutic Index
- Accession Number
- DBCAT004675
- Description
Not Available
- Drugs
Drug Drug Description Warfarin A vitamin K antagonist used to treat venous thromboembolism, pulmonary embolism, thromboembolism with atrial fibrillation, thromboembolism with cardiac valve replacement, and thromboembolic events post myocardial infarction. Phenytoin An anticonvulsant drug used in the prophylaxis and control of various types of seizures. Ifosfamide An alkylating and immunosuppressive agent used in chemotherapy for the treatment of cancers, including testicular cancer, ovarian cancer, cervical cancer, osteocarcinoma, bladder cancer, small cell lung cancer, and non-Hodgkin's lymphoma. Cyclophosphamide A nitrogen mustard used to treat lymphomas, myelomas, leukemia, mycosis fungoides, neuroblastoma, ovarian adenocarcinoma, retinoblastoma, and breast carcinoma. Imipramine A tricyclic antidepressant indicated for the treatment of depression and to reduce childhood enuresis. Phenobarbital A long-lasting barbiturate and anticonvulsant used in the treatment of all types of seizures, except for absent seizures. - Drugs & Drug Targets