Tissue Plasminogen Activator

DBCAT004683Therapeutic category

A proteolytic enzyme in the serine protease family found in many tissues which converts PLASMINOGEN to FIBRINOLYSIN. It has fibrin-binding activity and is immunologically different from UROKINASE-TYPE PLASMINOGEN ACTIVATOR. A DrugBank category of 3 drugs. 3 of them are approved.

Drugs: Alteplase
Reteplase
Tenecteplase

What you can answer from here — as of July 16, 2019

3DrugsEach linked to its full drug card

Listed above

5Drug targetsEvery drug–target pair in the class, with bond type

63Marketed productsAcross the regions we cover, with dosage forms and routes

4Routes of administrationHow the drugs in this class are given

Which targets do Tissue Plasminogen Activator share, and which companies have late-stage candidates in this class?

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