Fibroblast Growth Factor 2, antagonists & inhibitors

All categories
Name
Fibroblast Growth Factor 2, antagonists & inhibitors
Accession Number
DBCAT004930
Description

Not Available

Drugs
DrugDrug Description
Basic Fibroblast Growth FactorBasic Fibroblast Growth Factor is not currently approved for any FDA or Health Canada approved indications.
PemigatinibA kinase inhibitor used to treat locally advanced or metastatic, unresectable cholangiocarcinoma in previously treated adult patients.
InfigratinibAn FGFR inhibitor used to treat locally advanced or metastatic cholangiocarcinoma in adults with a fibroblast growth factor receptor 2 (FGFR2) rearrangement.
Drugs & Drug Targets
DrugTargetType
PemigatinibCytochrome P450 3A4enzyme
PemigatinibFibroblast growth factor receptor 1target
PemigatinibFibroblast growth factor receptor 2target
PemigatinibFibroblast growth factor receptor 3target
PemigatinibFibroblast growth factor receptor 4target
PemigatinibP-glycoprotein 1transporter
PemigatinibATP-binding cassette sub-family G member 2transporter
PemigatinibSolute carrier family 22 member 2transporter
PemigatinibMultidrug and toxin extrusion protein 1transporter
InfigratinibCytochrome P450 3A4enzyme
InfigratinibMultidrug and toxin extrusion protein 1transporter
InfigratinibATP-binding cassette sub-family G member 2transporter
InfigratinibBile salt export pumptransporter
InfigratinibSolute carrier family 22 member 1transporter
InfigratinibSolute carrier family 22 member 2transporter
InfigratinibMultidrug and toxin extrusion protein 2transporter
InfigratinibP-glycoprotein 1transporter
InfigratinibSolute carrier organic anion transporter family member 1B1transporter
InfigratinibSolute carrier organic anion transporter family member 1B3transporter
InfigratinibApolipoproteinscarrier
InfigratinibDimethylaniline monooxygenase [N-oxide-forming] 3enzyme
InfigratinibFibroblast growth factor receptor 1target
InfigratinibFibroblast growth factor receptor 2target
InfigratinibFibroblast growth factor receptor 3target
InfigratinibFibroblast growth factor receptor 4target