Antimicrobial Peptides

Name
Antimicrobial Peptides
Accession Number
DBCAT005572
Description

Small peptides that play an important role in early innate and induced defenses against invading microbes. Most have positive overall charges and are referred to as cationic antimicrobial peptides.

Drugs
DrugDrug Description
ColistinA polymyxin antibiotic used to treat bacterial infections caused by susceptible Gram negative bacteria.
ColistimethateAn antibiotic indicated for treatment of infections caused by susceptible strains of certain gram-negative bacilli. It is particularly useful for targeting sensitive strains of Pseudomonas aeruginosa.
OmigananInvestigated for use/treatment in bacterial infection and rosacea.
Polymyxin BA polymyxin antibiotic used to treat a wide variety of infections in the body.
IsegananIseganan is under investigation in clinical trial NCT00022373 (Iseganan Hydrochloride in Preventing Oral Mucositis in Patients Who Are Undergoing Radiation Therapy for Head and Neck Cancer).
PexigananPexiganan is under investigation in clinical trial NCT01594762 (Pexiganan Versus Placebo Control for the Treatment of Mild Infections of Diabetic Foot Ulcers).
P-113DFor the potential treatment of cystic fibrosis and bacterial infections.
Drugs & Drug Targets
DrugTargetType
ColistinBacterial outer membranetarget
ColistimethateBacterial outer membranetarget
Polymyxin BBacterial outer membranetarget
Polymyxin BSolute carrier family 15 member 2transporter