Antimicrobial Peptides
- Name
- Antimicrobial Peptides
- Accession Number
- DBCAT005572
- Description
Small peptides that play an important role in early innate and induced defenses against invading microbes. Most have positive overall charges and are referred to as cationic antimicrobial peptides.
- Drugs
Drug Drug Description Colistin A polymyxin antibiotic used to treat bacterial infections caused by susceptible Gram negative bacteria. Colistimethate An antibiotic indicated for treatment of infections caused by susceptible strains of certain gram-negative bacilli. It is particularly useful for targeting sensitive strains of Pseudomonas aeruginosa. Omiganan Investigated for use/treatment in bacterial infection and rosacea. Polymyxin B A polymyxin antibiotic used to treat a wide variety of infections in the body. Iseganan Iseganan is under investigation in clinical trial NCT00022373 (Iseganan Hydrochloride in Preventing Oral Mucositis in Patients Who Are Undergoing Radiation Therapy for Head and Neck Cancer). Pexiganan Pexiganan is under investigation in clinical trial NCT01594762 (Pexiganan Versus Placebo Control for the Treatment of Mild Infections of Diabetic Foot Ulcers). P-113D For the potential treatment of cystic fibrosis and bacterial infections. - Drugs & Drug Targets
Drug Target Type Colistin Bacterial outer membrane target Colistimethate Bacterial outer membrane target Polymyxin B Bacterial outer membrane target Polymyxin B Solute carrier family 15 member 2 transporter