Nuclear Export Inhibitors

Name
Nuclear Export Inhibitors
Accession Number
DBCAT005701
Description

Agents which inhibit nuclear export via blockade of exportin-1.

Drugs
DrugDrug Description
SelinexorSelinexor is indicated in combination with bortezomib and dexamethasone for the treatment of multiple myeloma in adult patients who have received at least one prior therapy. Selinexor is also indicated...
TriheptanoinTriheptanoin is a medium chain triglyceride indicated to provide calories and fatty acids to treat long chain fatty acid oxidation disorders.
Drugs & Drug Targets
DrugTargetType
SelinexorCytochrome P450 3A4enzyme
SelinexorSolute carrier organic anion transporter family member 1B3transporter
SelinexorExportin-1target
TriheptanoinAlbumincarrier