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Triheptanoin is triheptanoin is a medium chain triglyceride indicated to provide calories and fatty acids to treat long chain fatty acid oxidation disorders. Complications in lc-FAOD patients are reduced from approximately 60% to approximately 10% with the addition of triheptanoin.
- Mechanism
- Curator reviewed · 2 references
Triheptanoin is a source of heptanoate fatty acids, which can be metabolized without the enzymes of long chain fatty acid oxidation. In clinical trials, patients with lc-FAODs treated with triheptanoin experienced improvements in hypoglycemia, cardiomyopathy, and rhabdomyolysis.
- Primary indication
- Triheptanoin is a medium chain triglyceride indicated to provide calories and fatty acids to treat long chain fatty acid oxidation disorders (lc-FAODs).Curator reviewed · 1 structured indication
- Formula / weight
- C24H44O6 · 428.61 g/mol (avg)
- First approval
- Canada, 2021 · United States, 2020
- Also known as
- Glycerol triheptanoate · Glyceryl triheptanoate · Trienanthoin · Triheptanoic glyceride · Triheptylin
- Code names
- UX-007
- Brand names
- Dojolvi
Resolves to
PJHKBYALYHRYSK-UHFFFAOYSA-NSMILESCCCCCCC(=O)OCC(COC(=O)CCCCCC)OC(=O)CCCCCCWhat you can answer from here — as of July 11, 2026
Which other approved drugs treat the same conditions as Triheptanoin, and which companies have late-stage candidates in those indications?