Thiopurine Analogs

All categories
Name
Thiopurine Analogs
Accession Number
DBCAT002714
Description

Not Available

Drugs
DrugDrug Description
AzathioprineAn immunosuppressant used to prevent renal transplant rejection, treat rheumatoid arthritis, Crohn's disease, and ulcerative colitis.
MercaptopurineAn antineoplastic agent used to treat acute lymphocytic leukemia.
TioguanineA purine analogue antineoplastic agent used for the induction of remission, and for remission consolidation in patients with acute nonlymphocytic anemias.
Drugs & Drug Targets
DrugTargetType
AzathioprineInosine-5'-monophosphate dehydrogenase 1enzyme
AzathioprineAmidophosphoribosyltransferasetarget
AzathioprineInosine triphosphate pyrophosphataseenzyme
AzathioprineGMP synthase [glutamine-hydrolyzing]enzyme
AzathioprineThiopurine S-methyltransferaseenzyme
AzathioprineXanthine dehydrogenase/oxidaseenzyme
AzathioprineGlutathione S-transferase A1enzyme
AzathioprineGlutathione S-transferase A2enzyme
AzathioprineGlutathione S-transferase Mu 1enzyme
AzathioprineRas-related C3 botulinum toxin substrate 1target
AzathioprineCytochrome P450 1A2enzyme
AzathioprineHypoxanthine-guanine phosphoribosyltransferaseenzyme
AzathioprineNucleotide triphosphate diphosphatase NUDT15enzyme
AzathioprineEquilibrative nucleoside transporter 2transporter
AzathioprineSolute carrier family 28 member 3transporter
AzathioprineATP-dependent translocase ABCB1transporter
AzathioprineEquilibrative nucleobase transporter 1transporter
AzathioprineAlbumincarrier
AzathioprineInosine-5'-monophosphate dehydrogenase 2enzyme
MercaptopurineInosine-5'-monophosphate dehydrogenase 1target
MercaptopurineThiopurine S-methyltransferaseenzyme
MercaptopurineXanthine dehydrogenase/oxidaseenzyme
MercaptopurineHypoxanthine-guanine phosphoribosyltransferasetarget
MercaptopurineOrganic anion transporter 3transporter
MercaptopurineATP-binding cassette sub-family C member 4transporter
MercaptopurineATP-binding cassette sub-family C member 5transporter
MercaptopurineSodium/nucleoside cotransporter 2transporter
MercaptopurineSolute carrier family 28 member 3transporter
MercaptopurineEquilibrative nucleoside transporter 1transporter
MercaptopurineEquilibrative nucleoside transporter 2transporter
MercaptopurineAldehyde oxidaseenzyme
MercaptopurineAmidophosphoribosyltransferasetarget
MercaptopurineInosine-5'-monophosphate dehydrogenasetarget
TioguanineInosine-5'-monophosphate dehydrogenasetarget
TioguanineHypoxanthine-guanine phosphoribosyltransferaseenzyme
TioguanineATP-binding cassette sub-family C member 4transporter
TioguanineDNAtarget