Onychomycosis (DBCOND0000154)

Identifiers

Synonyms
Tinea unguium / Ringworm of nail / Fungal infection of nail / Nail fungal infection NOS / Onychomycosis (disorder)

Associated Data

Indicated Drugs and Targets
DrugDescriptionTargets
Efinaconazole
An antifungal agent used to treat onychomycosis, a fungal infection of the nail.
Terbinafine
An allylamine antifungal used to treat dermatophyte infections of toenails and fingernails as well as other fungal skin infections.
Tioconazole
An imidazole antifungal used to treat vulvovaginal candidiasis.
Clinical Trials
IdentifierTitleDrug(s)PurposePhaseStatus
NCT01819051
Pilot Study to Evaluate Plasma Treatment of OnychomycosisNo drug interventionstreatmentNot Availablecompleted
NCT00602251
Bioequivalency Study of Terbinafine Tablets Under Fed ConditionstreatmentNot Availablecompleted
NCT02644551
The Efficacy of CELEXT07 in the Treatment of Toenail Onychomycosistreatment2unknown_status
NCT01419847
Topical Penlac Nail Lacquer for Onychomycosis in Childrentreatment4completed
NCT01484145
Deposition of Terbinafine After Iontophoretic Application of ETS Terbinafine Gel in Subjects With Distal Subungual Onychomycosis in the Great Toenailtreatment2completed
NCT00730405
Efficacy and Safety Study of 4 Dose Regimens of Oral Albaconazole in Subjects With Distal Subungual Onychomycosistreatment2completed
NCT00253305
Topical Gel Anti-Fungal Agent for Tinea Unguiumtreatment2completed
NCT05809297
Diode Laser and Photodynamic Therapy Vs. Ciclopirox.treatment4not_yet_recruiting
NCT01039883
A Study to Compare the Blood Levels of Albaconazole in Healthy Subjects Who Have Received a Single Dose of 400 mg Albaconazole as a Tablet Versus Albaconazole as a Capsulebasic_science1completed
NCT00233493
Spread of Dermatophytes Among FamiliesNo drug interventionsNot AvailableNot Availableunknown_status
NCT02812771
Safety and Pharmacokinetics of Efinaconazole Topical Solution in Subjects With Mild to Severe Onychomycosistreatment4completed
NCT01145807
TDT 067 Onychomycosis Studytreatment3unknown_status
NCT05089409
A Study of ATB1651 in Adults With Mild to Moderate OnychomycosisNo drug interventionstreatment1completed
NCT02267356
A Study to Evaluate the Efficacy and Safety of Oral VT-1161 in Patients With Onychomycosis of the Toenailtreatment2completed
NCT03098615
Study Evaluating the Effect of Jublia on Dermatophytomastreatment4completed
NCT00459537
Efficacy, Safety and Tolerability of Topical 10% Terbinafine Hydrogen Chloride Versus 5% Amorolfine Nail Lacquer in Patients With Mild to Moderate Toenail Onychomycosistreatment3completed
NCT00771732
Using Light Therapy to Treat Toe Nail FungusNo drug interventionstreatment2unknown_status
NCT05415852
Lasers in OnychomycosisNo drug interventionstreatmentNot Availableunknown_status
NCT03216200
Early Feasibility Study to Evaluate the Efficacy of the RenewalNail™ Plasma Treatment System in Patients With Onychomycosis (Fungal Nail)No drug interventionstreatmentNot Availablecompleted
NCT05626270
Human Factors Testing for OTC Use of the Erchonia® LunulaLaserNo drug interventionsotherNot Availablecompleted
NCT02355899
Evaluation of the Suitability of PD P 506 A in the PDT of Distal Subungual Onychomycosis (DSO) of the Great Toenail.treatment2completed
NCT02588599
A Retrospective Analysis of the Effects of Low Level Laser Therapy on Toenail OnychomycosisNo drug interventionstreatmentNot Availablecompleted
NCT00935649
PinPointe FootLaser for the Treatment of OnychomycosisNo drug interventionstreatment2 / 3completed
NCT01615913
Optimizing the Treatment of Toenail Onychomycosis Using a New Transdermal Patch Combined With Terbinafine/Ketoconazoletreatment1unknown_status
NCT01528813
Erbium-doped Yttrium Aluminium Garnet Laser(Er:Yag)Associated With Amorolfine Lacquer in the Treatment of Onychomycosistreatment2unknown_status
NCT03405818
An Evaluation of the Safety and Pharmacokinetics of Tavaborole Topical Solution for the Treatment of Fungal Disease of the Toenail in Children and Adolescentstreatment4completed
NCT01246518
Efficacy and Safety of Two Treatment Regimens of Topical MOB015 in Adults With Distal Subungual OnychomycosisNo drug interventionstreatment2completed
NCT02242019
Study of Erchonia Low Level Laser Light Therapy to Treat Toenail FungusNo drug interventionstreatmentNot Availablecompleted
NCT00791219
Study Comparing SUBA™-Itraconazole With SPORANOX® (Itraconazole) in the Treatment of Onychomycosistreatment2completed
NCT05560841
Effectiveness and Safety of Nailner Brush 2in1 in OnychomycosisNo drug interventionstreatmentNot Availablecompleted
NCT00941317
Single-blind Evaluation of Device to Nail Micro-drilling in OnychomycosisNo drug interventionsother1completed
NCT02961634
Study Efficacy and Safety in Comparative Use of Investigational Product Adjuvant Treatment in Onychomycosissupportive_care3unknown_status
NCT01841996
Pharmacokinetics and Safety Study of ME1111 in Moderate to Severe Onychomycosis PatientsNo drug interventionstreatment1completed
NCT00938925
Effectiveness of Podiatry Care on Onychomycosis (EPOCAON)No drug interventionstreatmentNot Availablewithdrawn
NCT02464826
A Pilot Study - Safety and Efficacy of Nailprotex® for Onychomycosis TreatmentNo drug interventionstreatment4completed
NCT01790165
TDT 067 Open Label Multi-Dose Onychomycosis Studyscreening2completed
NCT04940520
Alpha-bisabolol for Onychomycosis Treatmenttreatment1completed
NCT00781820
Comparative Efficacy of Bifonazole Cream vs Placebo After Nail Ablation With Urea Pastetreatment3completed
NCT00680160
Absorption and Systemic Study of AN2690 in Patients With Moderate to Severe Onychomycosis (ADME I)treatment2completed
NCT01278394
Safety and Efficacy Study of Subjects With Onychomycosis of the Great Toenailtreatment2completed
NCT01400594
Safety & Efficacy Study of HTU-520 in the Treatment of Distal Subungual Onychomycosis of the ToenailNo drug interventionstreatment2completed
NCT02436291
Evaluation of the Efficacy of CURE-EX Treatment in OnychomycosisNo drug interventionstreatment4unknown_status
NCT01180491
A Clinical Investigation on Early Visible Effects of Application of K101 During 8 Weeks on Discoloured and Deformed Nails Resulting From OnychomycosisNo drug interventionsNot AvailableNot Availablecompleted
NCT01014962
A Study of the Effects of Increasing Doses of a Drug for the Treatment of Nail FungusNo drug interventionsbasic_science1completed
NCT00960089
Efficacy Study of LIQUICURE™ to Treat Toe Nail FungusNo drug interventionstreatmentNot Availablecompleted
NCT01534689
Study of the Use of Low Level Laser Light Therapy to Treat Toenail FungusNo drug interventionstreatmentNot Availablecompleted
NCT00679601
Absorption and Systemic Study of AN2690 in Patients With Moderate to Severe Onychomycosis (ADME II)treatment2completed
NCT02549001
Study to Evaluate the Efficacy and Safety of P-3058 10% Nail Solution in the Treatment of Toenail Onychomycosistreatment3completed
NCT02714504
Anti-mold Azole in the Prophylaxis for Invasive FusariosispreventionNot Availablecompleted
NCT05279846
A Vehicle-controlled Study of Topical MOB015B in the Treatment of Distal Subungual Onychomycosis (DSO)treatment3active_not_recruiting
NCT02019446
Laser Treatment for Onychomycosis in DiabetestreatmentNot Availableunknown_status
NCT01044381
Open-Label Pharmacokinetics (PK)/Safety Study of Luliconazole Solution, 10% in Distal Subungual Onychomycosistreatment1 / 2completed
NCT00680095
Cumulative Irritation Testother1completed
NCT02445495
Chart Review of the Efficacy of the GenesisPlus 1064 nm Nd:YAG Laser in the Treatment of OnychomycosisNo drug interventionsNot AvailableNot Availablecompleted
NCT05578950
Comparative Study Between Pulse Therapy With Oral Itraconazole Versus Continuous Oral Terbinafine Therapy for Treatment of Onychomycosistreatment1completed
NCT00679523
Safety and Efficacy Study of Subjects With Onychomycosis of the Great Toenailtreatment2completed
NCT01007708
The Safety and Efficacy of Topical IDP-108 Versus Vehicle in Patients With Onychomycosistreatment3completed
NCT00776464
Treating OnychomychosisNo drug interventionstreatment2 / 3unknown_status
NCT00491764
A Study to Evaluate Efficacy and Safety of Four Posaconazole Regimens With Placebo and Terbinafine in the Treatment of Toenail Onychomycosis (Study P05082AM2)(COMPLETED)treatment2completed
NCT01008033
Safety and Efficacy of Topical IDP-108 Versus Vehicle in Patients With Onychomycosistreatment3completed
NCT00443898
Efficacy, Safety, and Tolerability of Topical Terbinafine in Patients With Mild to Moderate Toenail Fungus of the Big Toenailtreatment3completed
NCT06485505
Isotretinoin Versus Excimer Light an Adjuvant in Treating Onychomycosistreatment1not_yet_recruiting
NCT02270697
Evaluation of an Oligonucleotide Array for Rapid Identification of Dermatophytes in Clinical SpecimensNo drug interventionsNot AvailableNot Availablecompleted
NCT00453271
Treatment of Mild to Moderate Distal Subungual Onychomycosis of the Toenailtreatment2completed
NCT03289871
Clinical Evaluation of the Efficacy of a Medical Device in Treatment of Toenail OnychomycosistreatmentNot Availablecompleted
NCT00356915
Itraconazole Tablets Vs. Itraconazole Capsules vs. Placebo in Onychomycosis of the Toenail.treatment3completed
NCT02022215
Efficacy and Safety Study of ME1111 in Patients With OnychomycosisNo drug interventionstreatment2completed
NCT06074315
Evaluation of the Effectiveness of Nail Genesis DLSO Product for OnychomycosisNo drug interventionstreatmentNot Availablerecruiting
NCT01014637
Efficacy, Safety and Cost-effectiveness of a Sequential Therapy With RV4104A Ointment, Ciclopiroxolamine Cream and Ciclopirox Film-forming Solution Compared With Amorolfine Nail Lacquer in Dermatophytic Onychomycosistreatment4unknown_status
NCT00602342
Bioequivalency Study of Terbinafine Tablets Under Fasting ConditionstreatmentNot Availablecompleted
NCT06175013
Evaluation of a Combination of Two Medical Devices and One Device Use in the Treatment of Toenail OnychomycosisNo drug interventionstreatmentNot Availablenot_yet_recruiting
NCT03168841
Efficacy and Safety of Efinaconazole 10% Solution in the Treatment of Onychomycosis in Diabetic Patientstreatment3completed
NCT00680134
Safety and Efficacy Evaluation of Topically Applied AN2690 Solutions for Subjects With Onychomycosistreatment2completed
NCT05482763
Mycosis Culture Collection From Dermatological IsolatedNot AvailableNot Availableactive_not_recruiting
NCT04327622
Prevalence and Risk Evaluation of Diabetic Complications of the Foot in A Large Canadian PopulationNo drug interventionsNot AvailableNot Availablecompleted
NCT04993066
Clinical Evaluation to Assess the Safety and Efficacy of GentleMax Pro PlusNo drug interventionstreatmentNot Availablecompleted
NCT05202366
An Open-label Study Evaluating the Effectiveness of CGB-400 Topical Gel for Fungal InfectionNo drug interventionsNot AvailableNot Availableunknown_status
NCT00808366
Efficacy and Safety of RV4104A Ointment in OnychomycosisNo drug interventionstreatmentNot Availableunknown_status
NCT00443820
Efficacy Safety, and Tolerability of Topical Terbinafine in Patients With Mild to Moderate Toenail Fungus of the Big Toenailtreatment3completed
NCT02343627
Safety and Efficacy of NVXT Solution in Mild-to-Moderate Fungal Infection of the Toe NailNo drug interventionstreatment2completed
NCT06254027
Clinical Investigation for the Evaluation of Efficacy and Safety of Two Medical Devices for Onychomycosis TreatmenttreatmentNot Availablenot_yet_recruiting
NCT02798380
Efficacy, Safety, and Tolerability of HTS-519 Insert in Patients With Toenail Fungus of the Big ToenailNo drug interventionstreatment2completed
NCT03244280
A Study of the Systemic Absorption of MOB015Bother1completed
NCT01208129
Safety and Efficacy of NAB001 in the Treatment of Mild to Moderate Onychomycosis of the ToenailsNo drug interventionstreatment3terminated
NCT02547701
Clinical Trial on Onychomycosis With P-3058 Nail Solution in Pediatric PopulationNo drug interventionstreatment3completed
NCT00768768
Iontophoretic Application of Terbinafine Gel to the Large Toe NailNo drug interventionstreatment1completed
NCT01208168
Safety & Efficacy of NAB001 in the Treatment of Mild to Moderate Onychomycosis of the ToenailsNo drug interventionstreatment3terminated
NCT00777868
A Dose-Ranging Study Evaluating the Safety and Efficacy of IDP-108 in Patients With Onychomycosistreatment2completed
NCT01996995
Laser Therapy for Onychomycosis in Patients Wih Diabetes at Risk for Diabetic Foot ComplicationsNo drug interventionstreatmentNot Availablecompleted
NCT06327295
A Study of ATB1651 in Adults With Mild to Moderate OnchomycosisNo drug interventionstreatment2not_yet_recruiting
NCT01915355
Pulsed Dye Laser Treatment of OnychomycosisNo drug interventionstreatmentNot Availablecompleted
NCT03814343
Topical Amphotericin B in 30% Dimethylsulphoxide in Treating of Non-dermatophytes Onychomycosistreatment4completed
NCT05491603
A Trial to Evaluate the Safety and Efficacy of DBI-001 Gel, DBI-002 Gel, and Aqueous Gel in Subjects With OnychomycosisNo drug interventionstreatment2suspended
NCT01851590
Resin vs. Amorolfine vs. Terbinafine Treatment in Onychomycosistreatment4completed
NCT05390190
Radiofrequency in OnychomycosisNo drug interventionstreatmentNot Availableunknown_status
NCT01452490
Diode Laser Treatment of OnychomycosisNo drug interventionsdevice_feasibilityNot Availablecompleted
NCT01666002
Treatment of Onychomycosis Using a 0.65 Millisecond Pulsed Nd:YAG 1064 nm LaserNo drug interventionstreatmentNot Availablecompleted
NCT00385502
A Trial of the Safety and Efficacy of EcoNail™ in the Treatment of Fungus Infections of the Great Toenailtreatment2completed
NCT02724384
Evaluating the Safety, Tolerability and Preliminary Efficacy of Plasma in Improving the Appearance of OnychomycosisNo drug interventionstreatmentNot Availableunknown_status
NCT02933879
Randomized, Placebo-Controlled, Double-Blind, Parallel-Group, Multi-Site Phase 2b Clinical StudyNo drug interventionstreatment2completed
NCT01080079
Efficacy and Safety Study of Iontophoretic Application of Terbinafine Gel in Subjects With Onychomycosistreatment2completed