HIV Wasting Syndrome (DBCOND0000270)

Identifiers

Synonyms

AIDS Wasting Syndrome / HIV wasting syndrome / Wasting syndrome due to acquired immunodeficiency syndrome (disorder)

Associated Data

Indicated Drugs and Targets

Drug	Description	Targets
Somatotropin	A recombinant human growth hormone used as replacement therapy in various conditions of growth failure, growth hormone deficiency, and weakness in children and adults.	Growth hormone receptortarget Prolactin receptortarget Cytochrome P450 1A2enzyme Cytochrome P450 2C19enzyme ATP-dependent translocase ABCB1transporter

Clinical Trials

Identifier	Title	Drug(s)	Purpose	Phase	Status
NCT00006064	The Effect of Anti-HIV Treatment on Body Characteristics of HIV-Infected Children	No drug interventions	Not Available	Not Available	completed
NCT00001079	A Study of Megestrol Acetate Alone or in Combination With Testosterone Enanthate Drug in the Treatment of HIV-Associated Weight Loss	Megestrol acetate Testosterone enanthate	treatment	2	completed
NCT00000854	A Study to Evaluate the Effect of Nandrolone Decanoate in Women With HIV-Associated Weight Loss	Nandrolone decanoate	treatment	1	completed
NCT00001077	A Comparison of Two Caloric Supplements in the Prevention of Weight Loss in Patients With AIDS Who Take Daily Multivitamin and Mineral Supplements	No drug interventions	Not Available	Not Available	completed
NCT00489528	Growth Hormone in the Treatment of HIV-Associated Wasting	Somatotropin	prevention	3	completed
NCT00000737	A Phase I/II Study to Evaluate Single Agent and Combination Therapy With Megestrol Acetate and Dronabinol for the Treatment of HIV-Wasting Syndrome	Dronabinol Megestrol acetate	treatment	1	completed
NCT00002127	A Phase II, Parallel Group, Randomized, Placebo-Controlled Study of the Safety and Efficacy of Thalidomide in Reducing Weight Loss in Adults With HIV Wasting Syndrome	Thalidomide	treatment	2	completed
NCT00006167	Nutrition Intervention in AIDS Wasting	Oxandrolone	treatment	4	completed
NCT00004664	Randomized Placebo-Controlled Study of Aerobic Exercise and Resistance Training Plus Megestrol Acetate for HIV-Wasting	Megestrol acetate	treatment	Not Available	completed
NCT00000925	A Study to Evaluate High Protein Supplementation in HIV-Positive Patients With Stable Weight Loss	No drug interventions	treatment	2	completed
NCT00002157	Compassionate Use Study of Two Dose Levels of Thalidomide in Adults With HIV Wasting Syndrome	Thalidomide	treatment	Not Available	completed
NCT00637572	Evaluate Weight Gain Using 2 Different Formulations of Megestrol Acetate Oral Suspension for AIDS-related Weight Loss	Megestrol acetate	treatment	2	completed
NCT00006158	AIDS Wasting in Women: Anabolic Effects of Testosterone	Testosterone	treatment	2	completed