Restless Legs Syndrome

DBCOND0003364Musculoskeletal and Connective Tissue DiseasesNervous System Diseases

Restless Legs Syndrome is the indication for 7 drugs in DrugBank. It is covered by 7 curated, structured indications.

Also known as
Restless Legs Syndrome (RLS) · Restless Leg Syndrome · Restless Legs · Ekbom Syndrome · Willis-Ekbom Disease
Classified under
Indicated drugs

Resolves to

Vocabularies
MeSHM0018926ICD-10G25.81SNOMED CT238973003MedDRA10012242UMLSC0035258

What you can answer from here — as of October 23, 2026

7Indicated drugsWith each drug's targets and mechanism
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7Structured indicationsPopulation, line of therapy, route and combination as fields, not prose
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142Clinical trialsPhase, status and sponsor resolved per trial
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1Contraindicated drugDrugs whose labels contraindicate them in this condition
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23Drugs reporting it as an adverse effectWith incidence where the label states it
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Which approved drugs for Restless Legs Syndrome share a target, and which companies have late-stage candidates against it?

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