Genitourinary tract infection (DBCOND0014024)

Identifiers

Synonyms

GU infections / Genitourinary infections / Genitourinary infection / Genitourinary tract infection NOS / Infectious disease of genitourinary system (disorder)

Associated Data

Indicated Drugs and Targets

Drug	Description	Targets
Amoxicillin	A penicillin derivative used for the treatment of infections caused by gram-positive bacteria, in particular streptococcal bacteria causing upper respiratory tract infections.	Solute carrier family 15 member 1transporter Solute carrier family 15 member 2transporter Solute carrier family 22 member 6transporter Cytochrome P450 2C8enzyme Albumincarrier Beta-lactamase 2enzyme Penicillin binding proteintarget
Ampicillin	A penicillin derivative used for the treatment of a variety of infections caused by gram-positive and gram-negative bacteria as well as some anaerobes.	Albumincarrier Organic cation/carnitine transporter 2transporter Solute carrier family 15 member 1transporter Solute carrier family 15 member 2transporter Penicillin-binding protein 2atarget Penicillin-binding protein 1btarget Penicillin-binding protein 3target Penicillin-binding protein 1Atarget Penicillin-binding protein 2Btarget Monocarboxylate transporter 1transporter Solute carrier family 15 member 1target Solute carrier family 15 member 2target Angiopoietin-1 receptortarget
Cephalexin	A first generation cephalosporin used to treat certain susceptible bacterial infections.	Albumincarrier Organic cation/carnitine transporter 2transporter Solute carrier family 15 member 1transporter Solute carrier family 15 member 2transporter Solute carrier family 22 member 6transporter Organic anion transporter 3transporter Multidrug and toxin extrusion protein 1transporter Penicillin-binding protein 3target Penicillin-binding protein 2atarget Penicillin-binding protein 1btarget Penicillin-binding protein 1Atarget Penicillin-binding protein 2Btarget

Clinical Trials

Identifier	Title	Drug(s)	Purpose	Phase	Status
NCT02721225	Prebiotic in Preventing Low Birth Weight	No drug interventions	prevention	Not Available	completed
NCT05977868	Comparing Oral Versus Parenteral Antimicrobial Therapy	Amoxicillin Ampicillin Avibactam Benzylpenicillin Cefadroxil Cefazolin Cefepime Cefpodoxime Ceftaroline fosamil Ceftazidime Cephalexin Ciprofloxacin Clavulanic acid Dalbavancin Daptomycin Delafloxacin Doxycycline Ertapenem Levofloxacin Linezolid Meropenem Metronidazole Moxifloxacin Oritavancin Oxacillin Piperacillin Rifampin Sulbactam Sulfamethoxazole Tazobactam Tigecycline Trimethoprim Vancomycin	treatment	4	enrolling_by_invitation