DB00567ApprovedInvestigationalVet approvedSmall moleculeCephalosporinsFirst-Generation Cephalosporins
Cephalexin is a first generation cephalosporin used to treat certain susceptible bacterial infections. This antibiotic contains a beta lactam and a dihydrothiazide.
- Mechanism
- Curator reviewed · 5 references
Cephalexin is a first generation cephalosporin antibiotic. Cephalosporins contain a beta lactam and dihydrothiazide. Unlike penicillins, cephalosprins are more resistant to the action of beta lactamase. Cephalexin inhibits bacterial cell wall synthesis, leading breakdown and eventualy cell death.
- Primary indication
- Cephalexin is indicated for the treatment of certain infections caused by susceptible bacteria.Curator reviewed · 7 structured indications
- Formula / weight
- C16H17N3O4S · 347.389 g/mol (avg)
- First approval
- Canada, 2012 · United States, 1971
- Also known as
- Cefalexin
- Code names
- LILLY-66873 · S-6437
- Brand names
Resolves to
Clinical / RWD
Structure
InChIKey
ZAIPMKNFIOOWCQ-UEKVPHQBSA-NSMILES[H][C@]12SCC(C)=C(N1C(=O)[C@H]2NC(=O)[C@H](N)C1=CC=CC=C1)C(O)=OWhat you can answer from here — as of September 23, 2026
6Protein targetsEach mapped to UniProt, with action and pharmacological actionListed above
6TransportersSubstrate / inhibitor direction, not just membershipListed above
Which drugs share a target with Cephalexin, and which of those have an active Phase 3 trial?
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