severe Nausea and vomiting (DBCOND0021212)

Identifiers

Synonyms

Not Available

Associated Data

Indicated Drugs and Targets

Drug	Description	Targets
Perphenazine	A phenothiazine used to treat schizophrenia as well as nausea and vomiting.	D(1A) dopamine receptortarget D(2) dopamine receptortarget Cytochrome P450 2D6enzyme Cytochrome P450 1A2enzyme Cytochrome P450 2C18enzyme Cytochrome P450 2C19enzyme Cytochrome P450 2C8enzyme Cytochrome P450 2C9enzyme Cytochrome P450 3A4enzyme Albumincarrier Calmodulintarget
Prochlorperazine	A phenothiazine derivative used in the treatment of schizophrenia and anxiety and to relieve severe nausea and vomiting.	D(2) dopamine receptortarget Cytochrome P450 2D6enzyme Histamine H1 receptortarget Alpha-1 adrenergic receptorstarget Alpha-2 adrenergic receptorstarget

Clinical Trials

Identifier	Title	Drug(s)	Purpose	Phase	Status
NCT05452174	Endeavor to Stop Nausea/Vomiting Associated With Pregnancy (E-SNAP)	Mirtazapine	treatment	1 / 2	terminated