Circulatory collapse and shock (DBCOND0025070)

Identifiers

Synonyms

Shock Circulatory / Circulatory shock / Hemodynamic shock / Shock, unspecified / Peripheral circulatory failure / Failure peripheral circulatory / Collapse peripheral circulatory / Collapse peripheral vascular / Collapse circulatory peripheral / Shock / Shock (disorder) / Collapse cardiovascular / Circulatory collapse / Cardiovascular collapse / Collapse circulatory / Shock vascular / Acute circulatory failure / Collapse vascular / Failure circulatory / Circulatory failure / Vascular collapse

Associated Data

Indicated Drugs and Targets

Drug	Description	Targets
Dopamine	A catecholamine neurotransmitter used to treat hemodynamic imbalances, poor perfusion of vital organs, low cardiac output, and hypotension.	D(1A) dopamine receptortarget Dopamine beta-hydroxylasetarget Amine oxidase [flavin-containing] Aenzyme Amine oxidase [flavin-containing] Benzyme Catechol O-methyltransferaseenzyme Solute carrier family 22 member 2transporter Solute carrier family 22 member 1transporter Solute carrier family 22 member 3transporter Organic cation/carnitine transporter 2transporter POU domain, class 5, transcription factor 1transporter D(1B) dopamine receptortarget D(2) dopamine receptortarget D(3) dopamine receptortarget D(4) dopamine receptortarget Sodium-dependent dopamine transportertarget Dopamine beta-hydroxylaseenzyme 5-hydroxytryptamine receptor 1Atarget 5-hydroxytryptamine receptor 7target D(1) dopamine receptortarget Sodium-dependent noradrenaline transportertarget Sodium-dependent serotonin transportertarget 5-hydroxytryptamine receptor 3Atarget 5-hydroxytryptamine receptor 3Btarget Superoxide dismutase [Cu-Zn]target Synaptic vesicular amine transportertarget

Clinical Trials

Identifier	Title	Drug(s)	Purpose	Phase	Status
NCT06320509	Interest of Urinary Oxygen Partial Pressure (PO2u) in Predicting the Onset or Recovery of Acute Renal Failure During Shock States - OXYpi Study	No drug interventions	screening	Not Available	recruiting
NCT03483753	Vasopressin or Norepinephrine in Vasoplegic Shock After Non-cardiac Surgery	Norepinephrine Vasopressin	treatment	2 / 3	withdrawn
NCT04357275	The RIsk Stratification in COVID-19 Patients in the ICU Registry	No drug interventions	Not Available	Not Available	active_not_recruiting
NCT06376318	Shock and Acute Conditions OutcOmes Platform	No drug interventions	Not Available	Not Available	active_not_recruiting
NCT05102734	Physiologic Effect of Topical Nitroglycerin on Microcirculation Capacity in Patients With Circulatory Shock.	Nitroglycerin	Not Available	Not Available	completed
NCT06265259	Efficacy of the Use of Vasopressin as a Primary Vasoconstrictor in Critically Ill Patients	Norepinephrine Vasopressin	treatment	4	recruiting
NCT05032261	ICU Norepinephrine Load	Norepinephrine	Not Available	Not Available	unknown_status