Primary apnea of premature newborns (DBCOND0025127)

Identifiers

Synonyms
Apneas of Prematurity / Apnea of Prematurity / Primary apnoea of premature newborns / Other apnea of newborn / Apnea of prematurity (disorder) / Infantile apnoea / Infantile apnea / Apnea of infancy (disorder)

Associated Data

Indicated Drugs and Targets
DrugDescriptionTargets
Caffeine
A stimulant present in tea, coffee, cola beverages, analgesic drugs, and agents used to increase alertness. It is also used in to prevent and treat pulmonary complications of premature birth.
Clinical Trials
IdentifierTitleDrug(s)PurposePhaseStatus
NCT01344317
The Effect of Stimulating Substances on Brain Activity of Preterm InfantsNo drug interventionsNot AvailableNot Availableunknown_status
NCT06639581
Pilot Study to Evaluate Doses of Mechanical Stimulus on the Effectiveness of Preterm BreathingNo drug interventionssupportive_careNot Availablecompleted
NCT06518603
Caffeine Citrate in Preterm Infants At Risk of Apnea in Zambiaprevention4not_yet_recruiting
NCT05968586
Non-Invasive Neurally Adjusted Ventilatory Assist (NAVA) Prone vs Supine in Premature InfantsNo drug interventionstreatmentNot Availablerecruiting
NCT06374147
"Prapela® SVS Incubator Pad for Apnea of PrematurityNo drug interventionstreatmentNot Availablenot_yet_recruiting
NCT01066728
CO2 Inhalation as a New Treatment Modality for Apnea of Prematuritytreatment2 / 3completed
NCT03414671
The Effect of Standardizing the Definition of a Clinically Significant Cardiopulmonary Event on Length of StayNo drug interventionsNot AvailableNot Availablecompleted
NCT03670732
CPAP vs.Unsynchronized NIPPV at Equal Mean Airway PressureNo drug interventionstreatmentNot Availableterminated
NCT06327152
Caffeine Use in the Management of Preterm Infantstreatment2recruiting
NCT06292299
The PARS Study: Paediatric Advanced Respiratory Service Study - An Observational Diagnostic Feasibility StudyNo drug interventionsNot AvailableNot Availablenot_yet_recruiting
NCT05393817
Caffeine Citrate Use and Electronic Activity of the Diaphragm (EDI) ChangesNot AvailableNot Availablecompleted
NCT02293824
Effect of Feedings on Caffeine in Premature InfantsNot AvailableNot Availablecompleted
NCT02860325
NIV-NAVA Versus Nasal Continuous Positive Airway Pressure (nCPAP) or Non Synchronized NIPPVNo drug interventionstreatmentNot Availablecompleted
NCT03651648
Apnea Treatment in Premature Infants Using an Automatic Vibro-tactile Stimulator Triggered by the Detection of Apnea-bradycardia.No drug interventionstreatmentNot Availablerecruiting
NCT04327466
Effect of High Frequency Oscillatory Highflow Nasal Cannula on Desaturations and Bradycardia in Preterm InfantsNo drug interventionstreatmentNot Availablecompleted
NCT01911182
Inhalation of Low Concentration of CO2 in Preterm Infants Not Responding to Caffeine for the Treatment of ApneaNo drug interventionstreatment2 / 3terminated
NCT00296231
Nasal High Frequency Ventilation in Preterm Infants: A Pilot StudyNo drug interventionstreatment1completed
NCT01408173
Clinical Study of Caffeine for Apnea of Prematuritytreatment3completed
NCT03340727
Moderately Preterm Infants With Caffeine at Home for Apnea (MoCHA) Trialtreatment3terminated
NCT00161694
Use of Sucrose to Relieve Pain During Eye Exams in InfantsNo drug interventionspreventionNot Availableterminated
NCT03292562
A Comparison of Methods of Discontinuing Nasal CPAP in Premature Infants <30 Weeks GestationNo drug interventionssupportive_careNot Availablecompleted
NCT00308789
A Trial of Infant Flow Biphasic Nasal Continuous Airway Pressure (NCPAP) Versus Infant Flow NCPAP for the Facilitation of Extubation in Infants </= 1250 GramsNo drug interventionstreatment2terminated
NCT04144712
Caffeine as Respiratory Stimulant in Preterm Infantsprevention1unknown_status
NCT00809055
MRI and Neurodevelopment in Preterm Infants Following Administration of High-Dose Caffeineprevention4completed
NCT04430790
Doxapram Therapy in Preterm Infants (DOXA Trial)treatment3recruiting
NCT02346864
Effect of Three-Stair-Position on Improvement of Apnea of PrematurityNo drug interventionspreventionNot Availablecompleted
NCT03298347
Caffeine for Preterm Infants With Apnea of Prematurity(AOP)treatmentNot Availableunknown_status
NCT04184245
Hemodynamic Responses to Cardio-respiratory Events in Preterm InfantsNo drug interventionsNot AvailableNot Availablecompleted
NCT06401083
The Effect of an Additional Pre-extubational Loading Dose of Caffeine-citratetreatment4recruiting
NCT02743988
Influence of Oxygen Target Range on Intermittent Hypoxemia in Preterm InfantstreatmentNot Availableunknown_status
NCT03084432
Effect of Caffeine on Preterm Infants' Bone Mineral ContentNo drug interventionsNot AvailableNot Availablecompleted
NCT03695900
Arterial Oxygen Saturation on Ventilatory Stability in Extremely Premature InfantsNo drug interventionsotherNot Availablecompleted
NCT02524249
Early Versus Late Caffeine for ELBW NewbornspreventionNot Availableterminated
NCT02641249
Non-invasive Intervention for Apnea of PrematurityNo drug interventionstreatmentNot Availablecompleted
NCT03298035
A Comparison of Non-invasive Ventilation Methods Used to Prevent Endotracheal Intubation Due to Apnea in Very Low Birth Weight InfantsNo drug interventionstreatmentNot Availablecompleted
NCT05878925
Nasal Olfactory Stimulation and Its Effect on Respiratory Drive in Preterm InfantsNo drug interventionstreatmentNot Availablerecruiting
NCT05298748
The Effect of Womb Recordings on Maturation of Respiratory Control in Preterm InfantsNo drug interventionspreventionNot Availablerecruiting
NCT01020357
Caffeine for Apnea of Prematurity-Sleep (CAP-S) Studytreatment3completed
NCT01643057
Stochastic Resonance Mattress (Physiological Interventions) and Biomarkers for Enhancing Neonatal HealthNo drug interventionsNot AvailableNot Availablecompleted
NCT04868565
Target Weaning Oxygen to Determine Cafffeine Duration for AOPtreatment4completed
NCT03086473
Early Caffeine in Preterm Neonatesprevention4unknown_status
NCT04123691
Cardio-respiratory Events in Preterm Infants During TransitionNo drug interventionsNot AvailableNot Availablecompleted
NCT00482040
Randomized Trial Investigating Four Nasal CPAP Systems in the Management of Apnea of PrematurityNo drug interventionstreatmentNot Availableterminated
NCT05196646
Detection of CardioRespiratory Events Using Acoustic Monitoring in Preterm Infants on CPAPNo drug interventionsNot AvailableNot Availablerecruiting
NCT00182312
Caffeine for Apnea of Prematurity (CAP)prevention3completed