upper gastrointestinal motility disorders (DBCOND0025455)

Identifiers

Synonyms

Gastrointestinal Motility Disorder / Gastrointestinal Motility Disorders / Gastrointestinal motility disorder NOS

Associated Data

Indicated Drugs and Targets

Drug	Description	Targets
Domperidone	A dopamine receptor antagonist used as a peristaltic stimulant and anti-emetic agent for dyspepsia, indigestion, epigastric pain, nausea, and vomiting.	D(2) dopamine receptortarget Cytochrome P450 3A4enzyme Cytochrome P450 3A5enzyme Cytochrome P450 3A7enzyme ATP-dependent translocase ABCB1transporter Cytochrome P450 1A2enzyme Cytochrome P450 2B6enzyme Cytochrome P450 2C8enzyme Cytochrome P450 2D6enzyme D(3) dopamine receptortarget

Clinical Trials

Identifier	Title	Drug(s)	Purpose	Phase	Status
NCT01026922	Use of an Ambulatory Capsule to Characterize Gastrointestinal Pressure Patterns in Children	No drug interventions	Not Available	Not Available	completed
NCT06631001	"The Effect of Abdominal Massage on Gastrointestinal Functions in Mechanically Ventilated Patients Receiving Enteral Nutrition in Intensive Care"	No drug interventions	treatment	Not Available	not_yet_recruiting
NCT04429802	The Effect of Prucalopride (Resolor®) on Gastric Motor Function and Gastric Sensitivity	Prucalopride	treatment	Not Available	completed
NCT04244877	Rifaximin's Effect on Covert Hepatic Encephalopathy With SIBO and Gastrointestinal Dysmotility	Rifaximin	treatment	3	withdrawn
NCT04208828	IVIG for Drug and Device Refractory Gastrointestinal Auto-Immune Neuropathy	No drug interventions	Not Available	Not Available	recruiting
NCT05268328	The Effect of Foot Reflexology After Cesarean Section	No drug interventions	Not Available	Not Available	unknown_status
NCT04764019	Intestinal Dysmotility in Patients With Functional Digestive Symptoms	No drug interventions	diagnostic	Not Available	unknown_status
NCT05989763	Interrogating the Pathophysiological Mechanisms of Constipation in Patients With Systemic Sclerosis	No drug interventions	treatment	Not Available	recruiting
NCT03552510	Oropharyngeal Administration of Mother's Milk in Preterm Infants and Gastrointestinal Motility	No drug interventions	supportive_care	Not Available	completed
NCT00793195	Can SMOFlipid®, A Composite Parenteral Nutrition Lipid Emulsion, Prevent Progression Of Parenteral Nutrition Associated Liver Disease In Infants?	Fish oil Medium-chain triglycerides Olive oil Omega-3 fatty acids Soybean oil	treatment	2	unknown_status
NCT01635608	Absorption of Paracetamol, Talinolol and Amoxicillin After Oral Administration Using Non-caloric and Caloric Water	Acetaminophen Amoxicillin Talinolol	basic_science	1	completed
NCT04988438	Gastrointestinal Motor Disorders (Esophageal and Anorectal) After COVID-19	No drug interventions	Not Available	Not Available	unknown_status
NCT02573519	Gastrointestinal Motility Among Diabetes Patients	Acetylcholine Pyridostigmine	other	Not Available	terminated
NCT02245165	Nitric Oxide Control of Migrating Motor Complex: L-NMMA Effects in Relation to Receptor Blockades	Nitric Oxide Tilarginine	basic_science	1	completed
NCT03012594	Lanreotide in the Treatment of Small Bowel Motility Disorders	Lanreotide	treatment	2	completed
NCT01644240	A Phase 1, Multiple Intravenous Dose Study to Examine Safety, Tolerability, and PK of Intravenous TD-8954, a 5-HT4 Receptor Agonist, in Healthy Subjects	Felcisetrag	other	1	terminated
NCT06347367	Short-term Effect of Exercise and Self-manual Approaches to Bloating - Distention	No drug interventions	treatment	Not Available	active_not_recruiting
NCT01394055	Study to Assess Pharmacodynamics of RM-131 in Patients With Diabetic Gastroparesis	No drug interventions	treatment	1	completed
NCT02673983	Safety and Efficacy Study of the FTRD System for Obtaining Full-thickness Intestinal Biopsies	No drug interventions	diagnostic	Not Available	withdrawn