refractory, metastatic Non small cell lung cancer (DBCOND0025490)
Identifiers
- Synonyms
- Refractory, metastatic non small-cell lung cancer / Refractory, metastatic Non-small cell lung cancer / Refractory, metastatic Non Small Cell Lung Cancer
Associated Data
- Indicated Drugs and Targets
Drug Description Targets Alectinib A kinase inhibitor used to treat anaplastic lymphoma kinase positive metastatic non small cell lung cancer.Ceritinib An antineoplastic kinase inhibitor used to treat anaplastic lymphoma kinase (ALK)-positive metastatic non-small cell lung cancer (NSCLC) in patients with inadequate clinical response or intolerance to crizotinib.- ALK tyrosine kinase receptortarget
- ATP-dependent translocase ABCB1transporter
- Cytochrome P450 2C9enzyme
- Cytochrome P450 3A4enzyme
Docetaxel A taxoid antineoplastic agent used in the treatment of various cancers, such as locally advanced or metastatic breast cancer, metastatic prostate cancer, gastric adenocarcinoma, and head and neck cancer.- Apoptosis regulator Bcl-2target
- Tubulin beta-1 chaintarget
- Cytochrome P450 3A4enzyme
- Cytochrome P450 3A5enzyme
- Cytochrome P450 3A7enzyme
- ATP-dependent translocase ABCB1transporter
- ATP-binding cassette sub-family C member 10transporter
- Cytochrome P450 1B1enzyme
- Microtubule-associated protein 2target
- Microtubule-associated protein 4target
- Microtubule-associated protein tautarget
- Solute carrier organic anion transporter family member 1B3transporter
- Solute carrier family 22 member 7transporter
- Broad substrate specificity ATP-binding cassette transporter ABCG2transporter
- ATP-binding cassette sub-family C member 2transporter
- Multidrug resistance-associated protein 1transporter
- Nuclear receptor subfamily 1 group I member 2target
- Clinical Trials
- Not Available