Generalized Anxiety Disorder (DBCOND0027966)

Identifiers

Synonyms
Anxiety Disorder Generalized / Anxiety Disorders Generalized / Generalized Anxiety Disorders / Generalized Anxiety Disorder (GAD) / Generalized Anxious Disorders / Generalized anxiety disorder / Neuroses, Anxiety / Anxiety neurosis (finding) / Anxiety neurosis / Anxiety state, unspecified / Anxiety state / Anxiety state (finding) / Generalised anxiety disorder / Generalized anxiety disorder (disorder) / Feeling anxious / Anxiety reaction / Reaction anxiety / Anxiety (finding) / Anxiety

Associated Data

Indicated Drugs and Targets
DrugDescriptionTargets
Alprazolam
A triazolobenzodiazepine with intermediate onset commonly used to treat panic disorders and generalized anxiety in addition to anxiety associated with depression.
Citalopram
A selective serotonin reuptake inhibitor (SSRI) used in the treatment of depression.
Clorazepic acid
A benzodiazepine used to treat anxiety, partial seizures, and alcohol withdrawal.
Duloxetine
A serotonin norepinephrine reuptake inhibitor used to treat generalized anxiety disorder, neuropathic pain, osteoarthritis, and stress incontinence.
Escitalopram
A selective serotonin re-uptake inhibitor used in the treatment of major depressive disorder (MDD), generalized anxiety disorder (GAD), and other select psychiatric disorders such as obsessive-compulsive disorder (OCD).
Mirtazapine
A tetracyclic antidepressant used in the treatment of major depression and is used off-label as a drug for insomnia and to increase appetite.
Opipramol
A medication to treat general anxiety and somatoform disorders.
No drug targets
Paroxetine
A selective serotonin reuptake inhibitor used to treat major depressive disorder, panic disorder, OCD, social phobia, generalized anxiety disorder, the vasomotor symptoms of menopause, and premenstrual dysphoric disorder.
Pregabalin
An anticonvulsant drug used to treat neuropathic pain conditions and fibromyalgia, and for the treatment of partial onset seizures in combination with other anticonvulsants.
Quetiapine
An atypical antipsychotic agent used for the management of bipolar disorder, schizophrenia, and major depressive disorder.
Sertraline
A selective serotonin reuptake inhibitor (SSRI) indicated to treat major depressive disorder, social anxiety disorder and many other psychiatric conditions.
Venlafaxine
A selective serotonin and norepinephrine reuptake inhibitor (SNRI) used for the treatment of major depression, generalized or social anxiety disorder, and panic disorder.
Clinical Trials
IdentifierTitleDrug(s)PurposePhaseStatus
NCT04524975
А Dose-finding Study to Assess the Efficacy and Safety of CD-008-0045 in Patients With Generalized Anxiety DisorderNo drug interventionstreatment2completed
NCT04598867
A Study to Assess the Efficacy and Safety of CD-008-0045 in Patients With Generalized Anxiety DisorderNo drug interventionstreatment3unknown_status
NCT05549102
CBT and the Neural Circuits of AnxietyNo drug interventionsNot AvailableNot Availablerecruiting
NCT03577106
A Pilot fMRI Study of TMS in Late-Life Severe WorryNo drug interventionstreatmentNot Availablecompleted
NCT05867680
Feasibility Trial of an Online Course (eMB) to Reduce Anxiety and Depression for Pregnant Women and Their PartnersNo drug interventionspreventionNot Availablecompleted
NCT02571790
Virtual Reality and Relaxation for the Treatment of Generalized Anxiety Disorders: a Comparative Study With Standard RelaxationNo drug interventionspreventionNot Availablecompleted
NCT03702803
Efficacy and Safety Study of a IMSS Developed Phytopharmaceutical for the Treatment of Anxiety.No drug interventionstreatment2unknown_status
NCT01971203
Efficacy of Extended-release Quetiapine (Seroquel XR) as Adjunctive Therapy to Cognitive Behavioral Therapy in the TreatNo drug interventionstreatmentNot Availablecompleted
NCT04421690
Computerized Cognitive Training in Middle-Aged Adults With Generalized Anxiety Disorder: A Pilot StudyNo drug interventionstreatmentNot Availablecompleted
NCT00902564
Escitalopram in Patients With Generalized Anxiety DisorderNo drug interventionstreatment4completed
NCT04751864
Brain Stimulation & Generalized Anxiety StudyNo drug interventionstreatment4active_not_recruiting
NCT04900064
Evaluation of Primary Care Behavioral Health (PCBH) With the Addition of Self-help CBT - A Randomized Multicenter TrialNo drug interventionstreatmentNot Availablerecruiting
NCT04714164
Cognitive Behavioral Therapy Group for Older Adults Delivered by TelethealthNo drug interventionstreatmentNot Availableterminated
NCT04811521
Patient-centered Treatment of Anxiety After Low-Risk Chest Pain in the Emergency RoomNo drug interventionstreatmentNot Availableactive_not_recruiting
NCT03232502
Pharmacogenetics in Primary Care PsychotropicsNo drug interventionstreatment3unknown_status
NCT03458702
The Effects of Emotional Exposure on State AnxietyNo drug interventionstreatmentNot Availablecompleted
NCT05411302
Augmenting Mental Health Support Through a Supportive Text Messaging ProgramNo drug interventionssupportive_careNot Availablerecruiting
NCT00012584
Treatment of Youth With ADHD and AnxietytreatmentNot Availablecompleted
NCT01066143
Generalized Anxiety and SeroquelNo drug interventionstreatmentNot Availableterminated
NCT03329287
Simplified Cognitive Behavioral Therapy for Generalized Anxiety Disorder and DepressionNo drug interventionstreatmentNot Availableunknown_status
NCT00703833
A Study of MK0777 Gel Extrusion Module (GEM) in the Treatment of Outpatients With Generalized Anxiety Disorder (0777-019)No drug interventionstreatment2completed
NCT06282133
Behavioural Experiments for Generalized Anxiety in Adolescents - Pilot StudyNo drug interventionstreatmentNot Availablerecruiting
NCT03709433
Open Trial of an ACT Skills Group and Mobile App for WorryNo drug interventionstreatmentNot Availablecompleted
NCT06010654
Pivotal RCT to Test Safety and Efficacy of Digital Therapeutics 'ANZEILAX' for Managing Generalized Anxiety DisorderNo drug interventionstreatmentNot Availablerecruiting
NCT00236054
A 10-Week Efficacy and Safety Study for of Gabitril in the Treatment of Adults With Generalized Anxiety Disordertreatment3completed
NCT01033851
Stress Reduction Techniques and Anxiety: Therapeutic and Neuroendocrine EffectsNo drug interventionstreatment4completed
NCT05375851
Digital Interventions as an Add-on Tool in Generalized Anxiety Disorder TreatmentNo drug interventionstreatmentNot Availablerecruiting
NCT06361953
Comparing the Efficacy of Two Neurofeedback Protocols for Generalized Anxiety DisorderNo drug interventionstreatmentNot Availablecompleted
NCT03469453
Internet-delivered CBT for Adolescents With GADNo drug interventionstreatmentNot Availablecompleted
NCT06506253
Massage for GAD: Neuroimaging and Clinical Correlates of ResponseNo drug interventionstreatmentNot Availableactive_not_recruiting
NCT04846777
Brief Smartphone Treatment StudyNo drug interventionstreatmentNot Availablerecruiting
NCT00616447
rTMS Treatment in Patients With General Anxiety DisorderNo drug interventionstreatmentNot Availablecompleted
NCT02028247
Psychotherapy for Anxiety in Children With Autism Spectrum DisorderNo drug interventionstreatmentNot Availablecompleted
NCT01416805
Computerized Cognitive Behavioral Therapy for Childhood Anxiety in Community Health CentersNo drug interventionstreatment3completed
NCT00645983
Chamomile Therapy for Generalized AnxietyNo drug interventionstreatment4completed
NCT05467683
CO2 Reactivity as a Biomarker of Non-Response to Exposure-Based TherapyNo drug interventionstreatmentNot Availablerecruiting
NCT06537128
Internet-delivered Cognitive-Behavioral Therapy for Adolescents With Autism and AnxietyNo drug interventionstreatmentNot Availablenot_yet_recruiting
NCT01244711
Open-Label Pilot Study to Examine the Value of Substituting Quetiapine for BenzodiazepinesNo drug interventionstreatment4terminated
NCT02266693
Transdiagnostic iCBT for Depression and AnxietyNo drug interventionstreatmentNot Availablecompleted
NCT01203293
Cognitive Behavioral Therapy (CBT) for Latinos With Generalized Anxiety Disorder in the General Medical SectorNo drug interventionstreatment1completed
NCT05849493
Effects and Mechanisms of Change of Internet Delivered Cognitive Behavior Therapy for Generalized Anxiety DisorderNo drug interventionstreatmentNot Availablerecruiting
NCT00961493
RCT of an Acceptance-based Behavior Therapy for GADNo drug interventionstreatmentNot Availablecompleted
NCT00734071
An Efficacy and Safety Study of Vortioxetine (Lu AA21004) in Treating Generalized Anxiety DisorderNo drug interventionstreatment3completed
NCT02806271
Short-Term Efficacy and Mechanisms of Change of a Worry Postponement Intervention for Generalized Anxiety DisorderNo drug interventionstreatmentNot Availablecompleted
NCT00052078
Child and Adolescent Anxiety Disorders (CAMS)treatment3completed
NCT01958788
Testing Beliefs About Uncertainty in the Treatment of Generalized Anxiety DisorderNo drug interventionstreatmentNot Availablecompleted
NCT01160588
Brain Markers of Anxiety Disorders and SSRI/CBT Treatment in Children and AdolescentsNo drug interventionsNot AvailableNot Availablecompleted
NCT02756507
Transdiagnostic REBT Prevention Program for AdolescentsNo drug interventionspreventionNot Availablecompleted
NCT02739607
Internet-delivered Transdiagnostic Intervention for Anxiety and DepressionNo drug interventionstreatmentNot Availableunknown_status
NCT03528109
Improving Access to Child Anxiety TreatmentNo drug interventionstreatmentNot Availablerecruiting
NCT02306356
Internet-delivered Treatment for Children With Anxiety Disorders in a Rural Area; an Open Trial in a Clinical SettingNo drug interventionstreatmentNot Availablecompleted
NCT01178385
Cognitive-Behavioral Treatment for Anxiety Disorders in Children With Autism Spectrum DisordersNo drug interventionstreatment2 / 3completed
NCT00141115
Levetiracetam for the Treatment of Alcohol Dependence and Anxietytreatment2completed
NCT00537615
An Open-label Study to Investigate the Absorption, Metabolism and Excretion of Radiolabeled PD 0332334 in Six Healthy Male VolunteersNo drug interventionsdiagnostic1completed
NCT00593515
Effects of Parental Behavior on Child Anxiety RegulationNo drug interventionstreatment2completed
NCT01285115
The Comparative Clinical Study of Gamisoyosan on Anxiety of Generalized Anxiety Disorder According to Dosage FormNo drug interventionstreatment3completed
NCT02648737
Cognitive Behavioural Therapy for Anxiety Disorders in PDNo drug interventionstreatmentNot Availablecompleted
NCT00711737
Study of the Changes in Metabolic Parameters in Patients Treated With Escitalopram for Six MonthsNo drug interventionsNot AvailableNot Availablecompleted
NCT05748652
Generalized Anxiety Therapy EffectivenessNo drug interventionstreatmentNot Availablecompleted
NCT00951652
Efficacy of Adding Interpersonal and Emotional Processing Therapy Techniques to Cognitive Behavioral Therapy to Treat Generalized Anxiety DisorderNo drug interventionstreatmentNot Availablecompleted
NCT00662259
Drug Treatment Validation of Functional Magnetic Resonance Imaging in Generalized Anxiety DisorderNo drug interventionstreatment4completed
NCT04410575
Mental Health Assessment and Prescribing by Alberta PharmacistsNo drug interventionstreatmentNot Availablerecruiting
NCT03504475
Bioequivalence Study of Paroxetine Tablets and Paxil® Under Fasting and Fed Conditions in Chinese Healthy VolunteersNo drug interventionsprevention1completed
NCT03113175
Collabri Flex - Effect of Collaborative Care for People With Anxiety Disorders in General PracticeNo drug interventionstreatmentNot Availablecompleted
NCT01919970
Exposure-Focused Family-Based CBT for Youth With ASD and Comorbid AnxietyNo drug interventionstreatmentNot Availablecompleted
NCT06046170
Adaptation and Feasibility of the Community-Based Anxiety Program Tailored for Autism (CAPTA)No drug interventionstreatmentNot Availablerecruiting
NCT05530642
An Augmented Training Program for Preventing Post-Traumatic Stress Injuries Among Diverse Public Safety PersonnelNo drug interventionssupportive_careNot Availableactive_not_recruiting
NCT00635999
A Comparison Between Cognitive, Behavioral, and Cognitive-Behavioral Therapy for Generalized Anxiety DisorderNo drug interventionstreatmentNot Availablecompleted
NCT00219349
Cognitive-Behavioral Therapy and Escitalopram for Generalized Anxiety Disorder(GAD)treatment4completed
NCT01337713
Efficacy of Massage Therapy in the Treatment of Generalized Anxiety Disorder (GAD)No drug interventionstreatmentNot Availablecompleted
NCT02189213
Treatment of Pediatric Anxiety Disorders by Predicting Treatment Response Through Biocellular Markers and SleepNo drug interventionsdiagnosticNot Availableterminated
NCT00688818
Quetiapine in Co-Morbid Depressive and Anxiety DisordersNo drug interventionstreatmentNot Availablecompleted
NCT00674219
Memantine Treatment for Obsessive-compulsive Disorder and Generalized Anxiety DisorderNo drug interventionstreatment3completed
NCT05671419
Mindful Self-Compassion for Anxiety Disorders and DepressionNo drug interventionstreatmentNot Availablerecruiting
NCT02615119
Neural Basis of Meal Related Interoceptive Dysfunction in Anorexia NervosaNo drug interventionsbasic_scienceNot Availablecompleted
NCT03549819
Cannabidiol for the Treatment of Anxiety Disorders: An 8-Week Pilot StudyNo drug interventionstreatment3recruiting
NCT02690441
Physical Exercise Augmented CBT for GADNo drug interventionstreatmentNot Availableactive_not_recruiting
NCT05503017
Computerized Intervention Targeting the Error-Related Negativity and Balance N1 in Anxious ChildrenNo drug interventionsbasic_scienceNot Availablerecruiting
NCT03143634
The Modular Protocol for Mental Health (MPMH)No drug interventionstreatment1 / 2completed
NCT04225624
Improving Attentional and Cognitive Control in the Psychological Treatment of Intrusive ThoughtsNo drug interventionstreatmentNot Availablerecruiting
NCT00308724
Treating Late-Life Generalized Anxiety Disorder (GAD) in Primary CareNo drug interventionstreatmentNot Availablecompleted
NCT01312116
Psychodynamic Internet Treatment Versus Cognitive Behavioral Therapy (CBT) for Generalized Anxiety DisorderNo drug interventionstreatmentNot Availablecompleted
NCT01259596
Telephone Psychotherapy for Late-Life Generalized Anxiety Disorder (GAD)No drug interventionstreatmentNot Availablecompleted
NCT00120458
Black Cohosh as Alternative Therapy for Treating Menopause-Related AnxietyNo drug interventionstreatment4completed
NCT02811458
Clinical Trial of Transdiagnostic Cognitive-Behavior Therapy for Anxiety DisordersNo drug interventionstreatmentNot Availablecompleted
NCT00921063
A 5-Week Trial Of PD 0332334 And Alprazolam Extended Release Compared To Placebo In Patients With Generalized Anxiety DisorderNo drug interventionstreatment2completed
NCT00438386
Aripiprazole for the Treatment of Refractory AnxietyNo drug interventionstreatment4completed
NCT00586586
Effectiveness Study of CBT for Anxiety in ChildrenNo drug interventionstreatment2completed
NCT05124639
Clinical Trial of a Group Self-management Support Program for Anxiety DisordersNo drug interventionstreatmentNot Availableactive_not_recruiting
NCT03208348
Pilot Study of Virtual Reality for Providing Exposure Therapy to ChildrenNo drug interventionssupportive_careNot Availablecompleted
NCT06254157
Understanding of Participation Trends Within Generalized Anxiety Disorder Patients Involved in Clinical TrialsNo drug interventionsNot AvailableNot Availablenot_yet_recruiting
NCT03819426
Walking or High Intensity Exercise for AnxietyNo drug interventionstreatmentNot Availablecompleted
NCT04179526
Transdiagnostic Internet-delivered REBT Intervention for Adolescents' Internalizing ProblemsNo drug interventionstreatmentNot Availablecompleted
NCT04478526
Efficacy of Online CBT for GAD Compared to Pharmaceutical InterventionsNo drug interventionstreatmentNot Availablecompleted
NCT00426426
Comparing Cognitive Behaviour Therapy (CBT) With Metacognitive Therapy (MCT) in the Treatment of GADNo drug interventionstreatmentNot Availablecompleted
NCT02256566
Cognitive Training for Mood and Anxiety DisordersNo drug interventionstreatmentNot Availablecompleted
NCT02150265
Effectiveness of Six Sessions CBT for Adolescents With Emotional Problems in Community ClinicsNo drug interventionstreatmentNot Availablecompleted
NCT03051074
Examining the Effects of Reduced Environmental Stimulation on AnxietyNo drug interventionsbasic_scienceNot Availablecompleted
NCT00868374
Quetiapine Extended Release (XR) Treatment of Major Depressive Disorder With Comorbid Generalized Anxiety DisorderNo drug interventionstreatment3terminated
NCT01570374
Internet-based Treatment of Generalized Anxiety DisorderNo drug interventionstreatmentNot Availablecompleted
NCT01342120
PHARMO Institute Seroquel Safety StudyNo drug interventionsNot AvailableNot Availablecompleted
NCT00731120
Study of Efficacy and Safety of Vortioxetine (Lu AA21004) in Treating Generalized Anxiety DisorderNo drug interventionstreatment3completed
NCT05203731
Level of Physical Activity and Fear LearningNo drug interventionsbasic_scienceNot Availablerecruiting
NCT01032473
Mechanisms of Sleep Disturbance in Children With Generalized Anxiety Disorder (GAD)No drug interventionsNot AvailableNot Availableunknown_status
NCT02572973
Acoustic Neuromodulation (ANM) for Youth With Anxiety DisordersNo drug interventionstreatmentNot Availableterminated
NCT00744627
Efficacy and Safety of Vortioxetine (Lu AA21004) for Treatment of Generalized Anxiety Disorder in Adults.No drug interventionstreatment3completed
NCT00620776
Combined Treatment for Generalized Anxiety Disorder (GAD)No drug interventionstreatment2completed
NCT04569760
Cannabinoids for the Treatment of Anxiety Disorders: An 8-Week Pilot StudyNo drug interventionstreatment3withdrawn
NCT05118594
Testing a Precision Psychotherapy System for Low-income PatientsNo drug interventionstreatmentNot Availablenot_yet_recruiting
NCT04557891
Low-Intensity Focused Ultrasound Pulsation (LIFUP) for the Treatment of Generalized Anxiety Disorder (GAD)No drug interventionstreatmentNot Availablerecruiting
NCT01304862
Electronic Self-management Resource Training for Mental HealthNo drug interventionstreatmentNot Availablecompleted
NCT00800280
Evaluating The Effects Of Cimetidine On The Elimination Of PD 0332334 From The BodyNo drug interventionsNot Available1terminated
NCT02807480
Approach-Avoidance Conflict-a Multi-level Predictor for Therapy ResponseNo drug interventionsbasic_scienceNot Availablecompleted
NCT00569829
Modular Cognitive Behavioral Therapy for the Treatment of Child Anxiety Disorders in Elementary School SettingsNo drug interventionstreatment2completed
NCT02051192
Brief Behavioral Treatment for Anxiety in Young ChildrenNo drug interventionstreatment1 / 2completed
NCT03768544
Self-help Guided by Lay Providers for Anxiety in Older AdultsNo drug interventionstreatmentNot Availablecompleted
NCT01072344
Long Term Chamomile Therapy for AnxietyNo drug interventionstreatment3completed
NCT03522844
Treatments for Anxiety: Meditation and EscitalopramNo drug interventionstreatment4completed
NCT04060940
Emotion Regulation Therapy for Clinical Worry and RuminationNo drug interventionstreatmentNot Availablecompleted
NCT06243640
Phase 3 Clinical Trial of Buagafuran Capsules in the Treatment of GADNo drug interventionstreatment3recruiting
NCT00236067
A 10-Week Study for Efficacy and Safety Study of Gabitril in the Treatment of Adults With Generalized Anxiety Disordertreatment3completed
NCT01766401
Safety, Efficacy and Tolerability of Vilazodone in Patients With Generalized Anxiety DisorderNo drug interventionstreatment3completed
NCT05772104
Randomized Clinical Trial of Shugan Jieyu Capsule in Generalized Anxiety DisorderNo drug interventionstreatment3not_yet_recruiting
NCT05573672
Dietary Counselling Plus Omega-3 Supplementation in the Treatment of Generalized Anxiety DisorderNo drug interventionstreatment2completed
NCT04965272
A Study To Assess Adverse Events and Change in Disease Activity With Oral Cariprazine When Added to Antidepressant Therapies (ADTs) Compared to Placebo in Adult Participants With Generalized Anxiety Disorder (GAD) Who Have Had an Inadequate Response to ADTs AloneNo drug interventionstreatment2withdrawn
NCT00658372
A 10-week Study Evaluating the Efficacy and Safety of PD 0332334 in Patients With Generalized Anxiety Disorder (2)No drug interventionstreatment3terminated
NCT03925168
Music Therapy and Dialysis: A Pilot Investigation Into the Effectiveness of Patient-Selected Music Interventions on Physiological, Psychological, and Quality-of-Life OutcomesNo drug interventionstreatmentNot Availablecompleted
NCT05820568
Internet Delivered Cognitive Behavior Therapy Based on Intolerance of UncertaintyNo drug interventionstreatmentNot Availablecompleted
NCT05967468
Evaluation of Family-Based Behavioral Treatments for Youth With Anxiety and Obsessive-Compulsive DisorderNo drug interventionstreatmentNot Availablerecruiting
NCT00347269
Primary Care Intervention Strategy for Anxiety DisordersNo drug interventionstreatment4completed
NCT00329446
Safety & Efficacy Study of Quetiapine Fumarate (SEROQUEL®) vs. Placebo & Active Control in Generalized Anxiety DisorderNo drug interventionstreatment3completed
NCT05785312
Development of Online EMDR Therapy System and Its Comparative Testing With Face-to-Face EMDR Therapy for Treatment of Anxiety and Depressive Disorders in PakistanNo drug interventionstreatmentNot Availablenot_yet_recruiting
NCT06563310
Neurofeedback Enhanced Cognitive Reappraisal Training - Phase 4No drug interventionsbasic_scienceNot Availablenot_yet_recruiting
NCT01607710
Locating Regions of Interest in Generalized Anxiety Disorder Using Function Magnetic Resonance Imaging (fMRI)No drug interventionsNot AvailableNot Availablecompleted
NCT00413010
Pregabalin in the Treatment of Patients With Generalized Anxiety Disorder (GAD).No drug interventionstreatment3completed
NCT04901481
Empower Neuromodulation System - Pilot Study for Anxiety TreatmentNo drug interventionstreatmentNot Availableterminated
NCT00322595
Efficacy and Safety Study of Seroquel SR in the Treatment of Generalized Anxiety DisorderNo drug interventionstreatment3completed
NCT03930095
Efficacy of an Acceptance-based Group Behavioral Therapy for Generalized Anxiety Disorder.No drug interventionstreatmentNot Availablecompleted
NCT06124014
CES for the Treatment of GAD in Young AdultsNo drug interventionstreatmentNot Availablerecruiting
NCT05749055
ENCALM: a Study of ENX-102 As a Monotherapy Treatment in Patients with Generalized Anxiety DisorderNo drug interventionstreatment2recruiting
NCT00774150
Transdisciplinary Studies of CBT for Anxiety in Youth: Child Anxiety Treatment StudyNo drug interventionstreatmentNot Availablecompleted
NCT03917550
RECOVERY: A Transdiagnostic Intervention for Anxiety and DepressionNo drug interventionstreatmentNot Availableunknown_status
NCT06134323
Transcutaneous Vagus Nerve Stimulation for Generalized Anxiety DisorderNo drug interventionstreatmentNot Availablerecruiting
NCT00071708
Duloxetine Compassionate Use in Patients Who Have Completed a Previous Neuroscience Duloxetine Clinical TrialNot AvailableNot Availableno_longer_available
NCT00658008
A 10-week Study Evaluating the Efficacy and Safety of PD 0332334 in Patients With Generalized Anxiety Disorder (1)No drug interventionstreatment3terminated
NCT05427708
Respiratory Training vs Interoceptive Exposure in the Treatment of Transdiagnostic Pathological AnxietyNo drug interventionstreatmentNot Availablerecruiting
NCT04754438
Comparing the Efficacy of e-CBT to Mental Health Coaching for GADNo drug interventionstreatmentNot Availableactive_not_recruiting
NCT01563003
Cognitive Behavioral Therapy for Anxiety Disorders in Adolescents With AutismNo drug interventionstreatmentNot Availablecompleted
NCT03899090
Floatation-REST (Reduced Environmental Stimulation Therapy) for Anxiety and DepressionNo drug interventionstreatmentNot Availableactive_not_recruiting
NCT00329264
Safety & Efficacy Study of Quetiapine Fumarate (SEROQUEL®) vs. Placebo in Generalized Anxiety DisorderNo drug interventionstreatment3completed
NCT01687764
Combination of Active or Placebo Attentional Bias Modification Treatment (ABMT) to Either Cognitive Behavioral Group Therapy (CBGT) or Psychoeducational Control Intervention (PCI) for Anxiety Disorders in ChildrenNo drug interventionstreatmentNot Availableunknown_status
NCT03072264
Randomized Clinical Trial of a Mindfulness Based Intervention in Generalized Anxiety DisorderNo drug interventionstreatmentNot Availablecompleted
NCT05895721
Virtual Reality for Generalized Anxiety DisordersNo drug interventionstreatmentNot Availableactive_not_recruiting
NCT06051721
A Study of a N, N-dimethyltryptamine (DMT) Analog (CYB004) in Participants With Generalized Anxiety Disorder (GAD)No drug interventionstreatment2recruiting
NCT04922502
Parent-based Treatment for Youth With Anxiety and Obsessive-compulsive DisorderNo drug interventionstreatment2 / 3completed
NCT02096484
A Feasibility Study of Group Metacognitive Therapy Versus Mindfulness Meditation TherapyNo drug interventionstreatmentNot Availablecompleted
NCT00662584
Repetitive Magnetic Transcranial Stimulation (rTMS) in the Treatment of Generalized Anxiety Disorder (GAD)No drug interventionstreatment3completed
NCT00167479
A Study of Risperidone Monotherapy in Bipolar Anxietytreatment4completed
NCT01912287
GATE: Generalized Anxiety - A Treatment EvaluationNo drug interventionstreatmentNot Availablecompleted
NCT03925987
Predicting Treatment Response to Exposure Therapy Using Carbon DioxideNo drug interventionsbasic_scienceNot Availablecompleted
NCT00953654
Exercise Training for the Treatment of Generalized Anxiety DisorderNo drug interventionstreatmentNot Availablecompleted
NCT05306977
rTMS Pilot for AnxietyNo drug interventionsbasic_scienceNot Availableterminated
NCT01947647
Transdiagnostic Psychotherapy for Veterans With Mood and Anxiety DisordersNo drug interventionstreatmentNot Availablecompleted
NCT00368745
Efficacy and Safety of Pregabalin vs Placebo for Generalized Anxiety Disorder (GAD) Symptoms in Subjects Discontinuing Benzodiazepine Treatment and Remaining 6 Weeks on Study Medication, Free From Benzodiazepine Use.No drug interventionstreatment3completed
NCT00961298
An Open Label Trial of Duloxetine in the Treatment of Irritable Bowel Syndrome and Comorbid Generalized Anxiety DisorderNo drug interventionstreatment4completed
NCT00787397
Sleep, Mood, and Behavior StudyNo drug interventionstreatmentNot Availablecompleted
NCT06480383
Study of ITI-1284 as an Adjunctive Treatment in Patients With Generalized Anxiety DisorderNo drug interventionstreatment2recruiting
NCT05040061
SkillJoy Clinical TrialNo drug interventionstreatmentNot Availablecompleted
NCT00803361
Duloxetine for the Treatment of Generalized Anxiety DisorderNo drug interventionstreatment3completed
NCT02082561
False Safety Behavior Elimination Therapy: A Randomized Study of a Brief Individual Transdiagnostic Treatment for Anxiety DisordersNo drug interventionstreatmentNot Availablecompleted
NCT06422728
The Effectiveness of Transdiagnostic CBT Protocol on Anxiety DisordersNo drug interventionstreatmentNot Availablenot_yet_recruiting
NCT04793828
A Transdiagnostic, Self-guided Internet Intervention ("Velibra") for Waitlist Patients With Anxiety DisordersNo drug interventionstreatmentNot Availablerecruiting
NCT03807193
Self-selected or Predetermined Internet-based Treatment for Generalized Anxiety Disorder With Different Types of SupportNo drug interventionstreatmentNot Availablecompleted
NCT00938093
Treatment of Late-life Anxiety in Primary Care SettingsNo drug interventionstreatmentNot Availablecompleted
NCT02810171
Dimensional Brain Behavior Predictors of CBT Outcomes in Pediatric AnxietyNo drug interventionstreatmentNot Availablecompleted
NCT03621371
Cognitive-behavioral Therapy for Generalized Anxiety Disorder in Primary CareNo drug interventionstreatmentNot Availablecompleted
NCT00539578
Treatment of Patients With Anxiety Disorder (0777-022)No drug interventionstreatment2completed
NCT04512378
Group CBT for Intolerance of UncertaintyNo drug interventionstreatmentNot Availablesuspended
NCT06278909
Trigeminal Nerve Stimulation in Treatment-resistant Generalized Anxiety Disorder: a Feasibility StudyNo drug interventionstreatmentNot Availablerecruiting
NCT01128309
Stress Reduction and Anxiety: Effects on the Function and Structure of the BrainNo drug interventionstreatmentNot Availablecompleted
NCT05527509
Risk and Resiliency Factors in the RCMP: A Prospective InvestigationNo drug interventionspreventionNot Availablerecruiting
NCT00266409
Trial to Compare Time to Response in the Symptoms of Anxiety to Concomitant Treatment With Niravam™ and an SSRI or SNRI to Treatment With an SSRI or SNRI Alone in Subjects With Generalized Anxiety Disorder or Panic DisorderNo drug interventionstreatment4completed
NCT03156556
Improving Access to the Treatment of Anxiety and Depression Among Young AdultsNo drug interventionstreatmentNot Availablecompleted
NCT03420456
Transcranial Pulse Near-Infrared Light in Generalized Anxiety Disorder: a Placebo-Controlled StudyNo drug interventionstreatmentNot Availableterminated
NCT00542685
A 10-Week Study Evaluating the Efficacy And Safety of PD 0332334 for the Treatment of Generalized Anxiety DisorderNo drug interventionstreatment3completed
NCT01844115
Safety, Efficacy and Tolerability of Vilazodone in (GAD) Generalized Anxiety DisorderNo drug interventionstreatment3completed
NCT05380115
Cognitive Behavioral Therapy (CBT) for Late Life AnxietyNo drug interventionssupportive_careNot Availablewithdrawn
NCT03206437
Effect of Mindfulness Meditation on Physiological Response to Unpredictable StimuliNo drug interventionstreatmentNot Availablecompleted
NCT00073632
Acceptance-Based Treatment for Generalized Anxiety DisorderNo drug interventionstreatment1completed
NCT04433832
Physical and Psychological Health Trajectories in the Context of Coronary Heart DiseaseNo drug interventionsNot AvailableNot Availableunknown_status
NCT03300232
Adapting an Effective CBT for Comorbidity to a Computer-Delivered FormatNo drug interventionstreatmentNot Availablecompleted
NCT03118752
Pragmatic Collaborative Care for Cardiac Inpatients With Depression or AnxietyNo drug interventionstreatmentNot Availablecompleted
NCT01172652
Ziprasidone in Bipolar Disorder With Comorbid Lifetime Panic or Generalized Anxiety Disorder(GAD)No drug interventionstreatment4completed
NCT03016052
Visual Mismatch Negativity in Attention Bias Modifcation Treatment for AnxietyNo drug interventionstreatmentNot Availablecompleted
NCT05023759
Anxiety Symptoms in Relation to Use of Hemp-derived, Full Spectrum Cannabidiol (CBD)No drug interventionsNot AvailableNot Availablecompleted
NCT06132659
Neurofeedback Enhanced Cognitive Reappraisal TrainingNo drug interventionsbasic_scienceNot Availablerecruiting
NCT00701675
Pharmacological Treatment of Generalized Anxiety Disorder in the ElderlyNo drug interventionstreatment4completed
NCT03188575
Effectiveness & Cost-effectiveness of Internet-delivered Interventions for Depression and Anxiety Disorders in IAPTNo drug interventionstreatmentNot Availableunknown_status
NCT00947570
Neural Functioning Underlying Anxiety and Its Treatment (The INSULA Study)No drug interventionsbasic_scienceNot Availablecompleted
NCT04780542
Internet-delivered Cognitive Behavioral Treatment of Depression and Anxiety in Latin American College StudentsNo drug interventionstreatmentNot Availableactive_not_recruiting
NCT00456742
Efficacy of Treatment for Generalized Anxiety DisorderNo drug interventionsNot AvailableNot Availablecompleted
NCT00044642
Lorazepam-Induced Toxicity in the Ageddiagnostic4completed
NCT00515242
Therapeutic Massage for Generalized Anxiety DisorderNo drug interventionstreatment1 / 2completed
NCT01815099
Transcranial Magnetic Stimulation Treatment for Generalized Anxiety DisorderNo drug interventionstreatmentNot Availableterminated
NCT01488799
Motivational Interviewing and Cognitive Behavioural Therapy for Generalized Anxiety DisorderNo drug interventionstreatmentNot Availablecompleted
NCT01482806
Online Treatments for Mood and Anxiety Disorders in Primary CareNo drug interventionstreatment2 / 3completed
NCT05906849
Where We All Meet: ACT Approach to Adolescents Anxiety DisordersNo drug interventionstreatmentNot Availablerecruiting
NCT00809536
Investigation Of How PD 0332334 And Metformin Are Eliminated From The Body When They Are Administered At The Same TimeNo drug interventionsNot Available1terminated
NCT03079336
Implementation of Psychological Treatment in Generalized AnxietyNo drug interventionstreatmentNot Availablecompleted
NCT01659736
Transcranial Magnetic Stimulation Treatment for Generalized Anxiety DisorderNo drug interventionstreatmentNot Availablecompleted
NCT02476136
Initial Severity and Antidepressant Efficacy for Anxiety Disorders: an Individual Patient Data Meta-analysisNo drug interventionsNot AvailableNot Availableunknown_status
NCT05064813
MBSR Mechanisms in GADNo drug interventionsbasic_scienceNot Availablerecruiting
NCT05393518
Electroclinical Correlation of AnxietyNo drug interventionshealth_services_researchNot Availablerecruiting
NCT03463018
Echinacea Angustifolia (AnxioCalm) in AnxietyNo drug interventionstreatment2terminated
NCT06071819
Clinical Markers of Panic and Generalized Anxiety DisorderNo drug interventionsNot AvailableNot Availablecompleted
NCT03414619
The Role of Cognitive Control in the Transdiagnostic Conceptualization of "Intrusive Thoughts"No drug interventionsdiagnosticNot Availablecompleted
NCT00765219
Cognitive Behavior Treatment of Older Adults With Generalized Anxiety Disorder in Primary CareNo drug interventionstreatmentNot Availablecompleted
NCT01614041
Tandospirone Citrate in the Treatment of Patients With Generalized Anxiety DisorderNo drug interventionstreatment4completed
NCT03829241
Randomized Trial of Adult Participants With Generalized Anxiety DisorderNo drug interventionstreatment3completed
NCT00788034
Relapse-prevention Study With Lu AA21004 (Vortioxetine) in Patients With Generalized Anxiety DisorderNo drug interventionstreatment3completed
NCT06376734
Search for Novel Transcranial Magnetic Stimulation (TMS) Targets for Mental IllnessNo drug interventionsbasic_science2not_yet_recruiting
NCT04931134
Treatment of Anxiety Disorders With Trigeminal Nerve StimulationNo drug interventionstreatmentNot Availableactive_not_recruiting
NCT06512324
Operation of Brain Stimulation Equipment Under Remote Viewing Effectiveness RegistryNo drug interventionsNot AvailableNot Availableenrolling_by_invitation
NCT03591224
Pharmacogenomic Testing to Optimize Antidepressant Drug TherapyNo drug interventionstreatmentNot Availablecompleted
NCT02382224
Worry Exposure for Generalized Anxiety DisorderNo drug interventionstreatmentNot Availablewithdrawn
NCT04364958
Decision Aid for Patients With Generalized Anxiety Disorder: Protocol for a Randomized Controlled TrialNo drug interventionshealth_services_researchNot Availablecompleted
NCT05284435
Internet-Based, Parent-Led Cognitive-Behavioral Therapy for Anxiety in Youth With ASDNo drug interventionstreatmentNot Availablecompleted
NCT00602563
Attention Training for Generalized Anxiety DisorderNo drug interventionstreatmentNot Availablecompleted
NCT01979263
Attention Bias Modification Treatment for Anxious YouthNo drug interventionstreatmentNot Availableterminated
NCT00105586
Drug Therapy for Generalized Anxiety Disorder Among the Elderlytreatment4completed
NCT05157386
Physical Exercise as Adjunctive Therapy for Affective Disorder and AnxietyNo drug interventionsNot AvailableNot Availableactive_not_recruiting
NCT05717439
Feasibility and ML Training Investigation of the Senseye DT for Diagnosis of Adults With PTSDNo drug interventionsNot AvailableNot Availablerecruiting
NCT03433625
6-Session Treatment for Generalized Anxiety DisorderNo drug interventionstreatmentNot Availablecompleted
NCT00481325
Study of Pexacerfont (BMS-562086) in the Treatment of Outpatients With Generalized Anxiety DisorderNo drug interventionstreatment2 / 3completed
NCT05800925
Triage Survey for Psychiatry Research EligibilityNo drug interventionsNot AvailableNot Availablerecruiting
NCT06218030
Adjunctive Treatment With L-methylfolate for Treatment-Resistant Generalized Anxiety Disorder: a Pilot StudyNo drug interventionsother4not_yet_recruiting
NCT00539357
A Pilot Study of Cranial Electrotherapy Stimulation[CES] for Generalized Anxiety DisorderNo drug interventionstreatment4completed
NCT01570426
Brain Imaging and Computer Games in Children With Either Bipolar Disorder, ADHD, Anxiety or Healthy ControlsNo drug interventionsNot AvailableNot Availableunknown_status
NCT00525226
Evaluating the Effects of Stress in PregnancyNo drug interventionsNot AvailableNot Availablecompleted
NCT01629966
Safety, Efficacy and Tolerability of Vilazodone in Generalized Anxiety DisorderNo drug interventionstreatment3completed
NCT00601965
Antidepressant Treatment Plus Cognitive Behavioral Therapy for Generalized Anxiety Disorder in Older AdultsNo drug interventionstreatmentNot Availablecompleted
NCT00668265
Anxiety in Recovering Opiate DependenceNo drug interventionstreatment4terminated
NCT03650465
Comparing Different CBT Approaches in GADNo drug interventionstreatmentNot Availablecompleted
NCT05883774
Effects of rTMS on the Anxiety State of Older Patients With GADNo drug interventionstreatmentNot Availablenot_yet_recruiting
NCT04111874
Parent-Led Cognitive-Behavioral Teletherapy for Anxiety in Youth With ASDNo drug interventionstreatmentNot Availablecompleted
NCT00330174
Acamprosate in Alcoholics With Comorbid Anxiety or DepressionNo drug interventionstreatment4completed
NCT01702220
Calmer Life: Testing the Effectiveness of a Treatment for AnxietyNo drug interventionstreatmentNot Availablecompleted
NCT05108220
Evaluation of Effects of CBD Products on Anxiety Among U.S. WomenNo drug interventionsNot AvailableNot Availablecompleted
NCT00595231
Exploratory Study to Evaluate the Effect of SYN111 (Rufinamide) in Patients With Generalized Anxiety Disorder (GAD)No drug interventionstreatment2completed
NCT05729373
A Clinical Study That Will Measure How Well SEP-363856 Works and How Safe it is in Adults With Generalized Anxiety DisorderNo drug interventionstreatment2 / 3recruiting
NCT05172427
Acceptability/Feasibility of IU InterventionNo drug interventionstreatmentNot Availableunknown_status
NCT00730691
Efficacy of Vortioxetine (Lu AA21004) in Treating Generalized Anxiety DisorderNo drug interventionstreatment3completed
NCT00658762
A 10-week Study Evaluating the Efficacy and Safety of PD 0332334 for the Treatment of Generalized Anxiety Disorder (3)No drug interventionstreatment3terminated
NCT02219880
Kava for the Treatment of Generalised Anxiety Disorder: A Double-Blind Randomised Placebo-Controlled TrialNo drug interventionstreatment4completed
NCT00579280
Quetiapine SR and Divalproex Sodium ER in the Treatment of Anxiety in Bipolar Disorder With Panic Disorder and/or GADNo drug interventionstreatment4completed
NCT01311180
A Clinical Trial to Study the Effects of Sensoril® for Patients With Generalized Anxiety DisorderNo drug interventionstreatment2completed
NCT01975480
Efficacy of SNRI Treatment on Prefrontality in Patients With GAD and Other ComorbitiesNo drug interventionstreatment4completed
NCT01491880
Treatment Study for Rural Latino Youth With AnxietyNo drug interventionstreatment1 / 2completed
NCT00624780
Safety and Efficacy Evaluation Of Pregabalin (Lyrica) With Patients With Generalized Anxiety DisorderNo drug interventionstreatment4completed
NCT01118780
A Study of Duloxetine in Elderly Generalized Anxiety DisorderNo drug interventionstreatment4completed
NCT01681329
Cognitive-Behavioral Treatment and Interpretation Modification Training for Adults With Generalized Anxiety DisorderNo drug interventionstreatmentNot Availablecompleted
NCT01565629
Computer- Assisted Cognitive-Behavioral Treatment for Anxiety Disorders in Children With Autism Spectrum DisordersNo drug interventionstreatmentNot Availablecompleted
NCT00000389
Treatment for Anxiety in Childrentreatment3completed
NCT03764644
Web-based Attention Bias Modification Treatment for Childhood Anxiety DisordersNo drug interventionstreatmentNot Availableterminated
NCT05574140
BreathinG-induced Myocardial and Cerebral Perfusion in Anxiety DisordersNo drug interventionsNot AvailableNot Availablerecruiting
NCT00951340
Desensitization and Cognitive Therapy in General Anxiety.No drug interventionstreatment1completed
NCT00613067
ERP N1 as a Treatment Predictor of Generalized Anxiety DisorderNo drug interventionstreatmentNot Availablecompleted
NCT01201967
A Collaborative Care Program to Improve Treatment of Depression and Anxiety Disorders in Cardiac PatientsNo drug interventionstreatment4completed
NCT00735267
A 52-Week Open-Label Safety Study of PD 0332334 in Subjects With Generalized Anxiety Disorder (GAD)No drug interventionstreatment3terminated
NCT03099772
CBT for GAD: Impact of Cognitive Processing on Treatment OutcomeNo drug interventionstreatmentNot Availablecompleted
NCT01075672
Outcomes of Cognitive Behavioral Therapy (CBT) Interventions Provided by Unlicensed ProfessionalsNo drug interventionstreatmentNot Availableactive_not_recruiting
NCT01906268
Attention Retraining for Anxiety Disorder Patients Resistent to AntidepressantsNo drug interventionstreatmentNot Availableunknown_status
NCT02310568
POC Study in Partially Responsive Generalized Anxiety DisorderNo drug interventionstreatment2terminated
NCT00352469
Trial of Seroquel SR for Alcohol Dependence and Comorbid AnxietyNo drug interventionstreatment4completed
NCT05330312
Controlled Investigation to Evaluate Impact of dCBT on Psychological Symptom Burden in Adult Subjects With PFNo drug interventionstreatmentNot Availableactive_not_recruiting
NCT00602212
Virtual Reality as Anxiety Management Tool for Generalized Anxiety DisorderNo drug interventionstreatmentNot Availablecompleted
NCT03585010
Brain Response Associated With Parent-based Treatment for Childhood Anxiety DisordersNo drug interventionstreatmentNot Availablecompleted
NCT00208910
Muscle Relaxation Therapy With Odorant CueNo drug interventionstreatmentNot Availablecompleted
NCT05970510
A Study to Evaluate Efficacy and Safety of Toludesvenlafaxine Hydrochloride Sustained-release Tablets in Generalized Anxiety Disorder.No drug interventionstreatment3recruiting
NCT00735995
Effectiveness of Cognitive Behavioral Therapy (CBT) for Child Anxiety Disorders in Community Clinics in NorwayNo drug interventionstreatment2completed
NCT03720795
Stepped-Care Cognitive-Behavioral Treatment for Youth With ASD and AnxietyNo drug interventionstreatmentNot Availablecompleted
NCT06243614
Phase Ⅲ Clinical Trial of Buagafuran Capsules in the Treatment of GADNo drug interventionstreatment3recruiting
NCT03507114
Rumination Focus Cognitive Behavior TherapyNo drug interventionstreatmentNot Availableunknown_status
NCT04274114
Treatment of Adults With Generalized Anxiety Disorder Using GlutamineNo drug interventionstreatment2terminated
NCT01507155
An Open Label Study of Clinical Utility and Patient Outcomes of the Genecept AssayNo drug interventionssupportive_careNot Availablecompleted
NCT05117255
Validating an Autonomous Interactive Internet-Based Delivery of an Empirically Supported Cognitive Behavioral Therapy for ComorbidityNo drug interventionstreatmentNot Availablerecruiting
NCT03440255
Transcutaneous Vagus Nerve Stimulation in Private Healthcare CenterNo drug interventionstreatmentNot Availablecompleted
NCT00616655
Generalized Anxiety Disorder Proof of Concept Efficacy and Safety Study of SEP-225441 (Eszopiclone) In GAD SubjectsNo drug interventionstreatment2completed
NCT05016050
Digital Therapeutic for Major Depressive Disorder (MDD) and Generalized Anxiety Disorder (GAD)No drug interventionstreatmentNot Availablecompleted
NCT03924323
A Study of Escitalopram in the Treatment of Children and Adolescents With Generalized Anxiety DisorderNo drug interventionstreatment4completed
NCT03785223
A 14 Week, Randomized, Placebo-Controlled Cross-Over Study of Methylphenidate Hydrochloride Controlled Release Capsules in Adult ADHD With and Without Anxiety Disorder ComorbidityNo drug interventionstreatment4completed
NCT00235508
Safety and Efficacy of Eszopiclone in Patients With Generalized Anxiety Disordertreatment4completed
NCT02552108
A Single-Component CBT for GADNo drug interventionstreatmentNot Availablecompleted
NCT00738738
6-Month Open-Label Safety Study Of PD 0332334 In Elderly Patients With Generalized Anxiety Disorder (GAD)No drug interventionstreatment3withdrawn
NCT03674138
Pharmacogenomic-Guided Antidepressant Drug Prescribing in Cancer PatientsNo drug interventionssupportive_careNot Availableactive_not_recruiting
NCT00374543
Ziprasidone for the Treatment of Generalized Anxiety in Patients With Bipolar DisorderNo drug interventionstreatment4terminated
NCT05249543
Transdiagnostic Versus Diagnosis-specific Cognitive-behavioral TherapyNo drug interventionstreatmentNot Availablerecruiting
NCT03445143
GATE: Generalized Anxiety - A Treatment EvaluationNo drug interventionstreatmentNot Availablenot_yet_recruiting
NCT02111395
Psychotherapy for Anxiety in Children With Autism Spectrum DisorderNo drug interventionstreatment3recruiting
NCT02662803
Clinical, Neurophysiological and Neuroendocrine Effects of Aerobe Exercise in Generalized Anxiety Disorder (GAD)No drug interventionstreatmentNot Availablecompleted
NCT02305797
EDG004 Treatment of Adult Patients With Generalized Anxiety Disorder (GAD)No drug interventionstreatment3completed
NCT06024239
A Study to Evaluate the Pharmacokinetics, Safety, and Tolerability of ABBV-932 in Healthy Adult Participants, Participants With Generalized Anxiety Disorder (GAD) and Participants With Bipolar Disorder (BPD)No drug interventionstreatment1recruiting
NCT02708472
Safety and Efficacy of Synchronized Transcranial Magnetic Stimulation for the Treatment of Generalized Anxiety DisorderNo drug interventionstreatmentNot Availablewithdrawn
NCT01470469
SPD503 in Subjects Aged 6-17 Years With Generalized Anxiety Disorder (GAD), Separation Anxiety Disorder (SAD), or Social Phobia (SoP)No drug interventionstreatment2completed
NCT05738850
Study to Assess Adverse Events and How ABBV-932 Oral Capsules Moves Through the Body of Healthy Adult ParticipantsNo drug interventionstreatment1completed
NCT03277339
Psycho-biological Substrates of Therapeutic Benefit of Thermal Cure on Generalized Anxiety DisordersNo drug interventionstreatment4completed