Aphthous Stomatitis (DBCOND0028367)
Identifiers
- Synonyms
- Stomatitis, Aphthous / Oral Aphthae / Aphthous stomatitis / Canker sore / Ulcers aphthous oral / Canker sores oral / Stomatitis aphthous / Aphtha / Aphtha (morphologic abnormality) / Aphthous ulcer of mouth (disorder) / Ulcer aphthous oral / Ulcer aphthous / Aphthous ulceration of skin and/or mucous membrane (disorder) / Aphthous ulcer / Recurrent oral aphthae / Recurrent aphthous stomatitis (disorder) / Aphthous ulcer recurrent / Recurrent aphthous ulcer (disorder)
Associated Data
- Indicated Drugs and Targets
Drug Description Targets Difluocortolone A topical corticosteroid used for the symptomatic treatment of inflammatory skin disorders like eczema, seborrheic eczema, lichen planus and psoriasis.- Annexin A3target
- Glucocorticoid receptortarget
- Cytochrome P450 3A4enzyme
- Cytochrome P450 3A5enzyme
Thalidomide A medication used to treat cancers, particularly newly diagnosed multiple myeloma, and erythema nodosum leprosum.- Cytochrome P450 2C19enzyme
- Cytochrome P450 2C9enzyme
- Prostaglandin G/H synthase 1enzyme
- Prostaglandin G/H synthase 2enzyme
- Cytochrome P450 3A5enzyme
- DNAtarget
- Protein cereblontarget
- alpha1-acid glycoproteintarget
- Cytochrome P450 3A4enzyme
- Cytochrome P450 1A1enzyme
- Cytochrome P450 2B6enzyme
- Tumor necrosis factortarget
Triamcinolone A glucocorticoid used to treat a wide variety of inflammatory conditions of organ systems and tissues.- Corticosteroid-binding globulincarrier
- Glucocorticoid receptortarget
- Cytochrome P450 3A4enzyme
- Prostaglandin G/H synthase 2enzyme
- Cholinesteraseenzyme
- Cytochrome P450 3A5enzyme
- Cytochrome P450 3A7enzyme
- Albumincarrier
- Clinical Trials
Identifier Title Drug(s) Purpose Phase Status NCT00000790 Thalidomide for Treatment of Oral and Esophageal Aphthous Ulcers and HIV Viremia in Patients With HIV Infection treatment 2 completed NCT02925182 Treatment of Recurrent Aphthous Stomatitis With Er,Cr:YSGG Laser Irradiation No drug interventions supportive_care Not Available completed NCT06416046 Efficacy of Photobiomodulation in the Treatment and Relief of Pain in Recurrent Aphthous Stomatitis No drug interventions treatment Not Available not_yet_recruiting NCT06622213 Mucoadhesive Film With/without Acmella Oleracea & Triamcinolone Acetonide for Aphthous Ulcers treatment 2 not_yet_recruiting NCT04884464 Hyaluronic Acid in Counteracting Aphthous Stomatitis Not Available Not Available completed NCT02789605 Effectiveness and Safety of Lactobacillus Rhamnosus Lcr35® in the Treatment of Recurrent Aphthous Stomatitis No drug interventions treatment 2 completed NCT02535962 Probiotics and Corticosteroids for Treating Periodic Fever, Aphthous Stomatitis, Pharyngitis, Cervical Adenitis (PFAPA) treatment 2 withdrawn NCT04677062 Safety, Galenic Acceptability and Efficacy of GV-328 Lozenges in Children With Oral Aphthosis No drug interventions treatment Not Available completed NCT00001601 Evaluation and Treatment of Oral Soft Tissue Diseases No drug interventions Not Available Not Available completed NCT05772338 Efficacy and Safety of BNP105 in the Treatment of Recurrent Aphthous Stomatitis No drug interventions treatment Not Available recruiting NCT00527306 Prevention of Recurrent Aphthous Stomatitis Using Vitamins No drug interventions treatment 3 completed NCT02890524 Tokushima Night Guard for Recurrent Aphthous Stomatitis No drug interventions prevention Not Available completed NCT05542173 Efficacy and Safety of BALI Association in the Treatment of Aphthous Ulcerations No drug interventions treatment 3 not_yet_recruiting NCT01293968 Therapeutic Effects of "Ibuprofen, Diphenhydramine and Aluminium MgS" on Recurrent Aphthous Stomatitis supportive_care 2 completed NCT01210014 Systemic Zinc Sulphate in Treatment of Recurrent Aphthous Ulcerations:A Doubleblind, Placebo Controled Study treatment 2 completed NCT00723268 Evaluation of Therapeutic Effect of 0.5 mg Colchicine and 5 mg Prednisolone on Oral Aphthae treatment 2 unknown_status