Psychomotor Agitation (DBCOND0028415)

Identifiers

Synonyms
Agitation, Psychomotor / Agitation,Psychomotor / Psychomotor agitation / Psychomotor restlessness / Psychomotor agitation (finding) / Psychomotor hyperactivity

Associated Data

Indicated Drugs and Targets
DrugDescriptionTargets
Benperidol
A neuroleptic butyrophenone derivative indicated in the treatment of psychoses, manic episodes, and psychomotor agitation.
No drug targets
Perazine
A phenothiazine antipsychotic used in the acute and chronic treatment of psychotic disorders.
Promazine
A phenothiazine used to manage schizophrenia.
Prothipendyl
A neuroleptic agent indicated in the treatment of restlessness and agitation in patients with underlying psychiatric conditions.
No drug targets
Valpromide
A valproic acid derivative used to treat epilepsy and as adjunct therapy for psychomotor agitation, depression, and manic episodes of bipolar disorder.
Clinical Trials
IdentifierTitleDrug(s)PurposePhaseStatus
NCT04947553
A Study to Assess the Long-term Safety and Efficacy of AXS-05 in Subjects With Alzheimer's Disease Agitationtreatment3enrolling_by_invitation
NCT05783505
A Multicomponent Intervention Program to Prevent and Reduce ICU Agitation and Physical Restraint UseNo drug interventionstreatmentNot Availablerecruiting
NCT03211897
Olanzapine, Haloperidol, Ziprasidone, Midazolam for Acute Undifferentiated AgitationNot AvailableNot Availablecompleted
NCT04075435
Cannabidiol Solution for the Treatment of Behavioral Symptoms in Older Adults With Mild Cognitive Impairment or Alzheimer's Dementiatreatment0recruiting
NCT04053426
Agitation Follow up After Introduction of a New Patient Care AlgorithmNo drug interventionsNot AvailableNot Availablecompleted
NCT03926520
Electroconvulsive Therapy (ECT) for Agitation in Dementia (AD)No drug interventionstreatmentNot Availablerecruiting
NCT06041646
Tachyphylaxis, Tolerance, & Withdrawal Post Treatment With Igalmi for Agitation in Schizophrenia or Bipolar Disordertreatment4completed
NCT04251910
Sub-Lingual Dexmedetomidine in Agitation Associated With Dementiatreatment1 / 2completed
NCT02504450
Outcomes of Antipsychotic Medication Used in the Emergency DepartmentNot AvailableNot Availablecompleted
NCT04957238
Physical Restraints in Intensive Care Unit PatientsNo drug interventionsotherNot Availablerecruiting
NCT03880084
Delirium, Agitation/Sedation, Pain and Dyspnea in Respiratory Intensive Care Unit (NIVILIUM)No drug interventionsNot AvailableNot Availablerecruiting
NCT04276883
Dexmedetomidine in the Treatment of Agitation Associated With Bipolar Disordertreatment3completed
NCT05612711
Dronabinol for Agitation in Dementia Crossover Trialtreatment2withdrawn
NCT04797715
Assessing Clinical Outcomes in Alzheimer's Disease AgitationNo drug interventionstreatment3completed
NCT04514432
Mindful Melody: Feasibility of Implementing Music Listening on an Inpatient Psychiatric Unit and Its Relation to the Use of As Needed Medications for Acute AgitationNo drug interventionsNot AvailableNot Availablecompleted
NCT03208452
The Effect of Intraoperative Magnesium Sulfate Infusion on the Occurrence of Emergence Agitationprevention4completed
NCT03110900
Inhaled Loxapine vs Intramuscular (IM) Haloperidol + Lorazepam for Agitationtreatment4terminated
NCT03899506
Olanzapine Versus Midazolam for AgitationNot AvailableNot Availableterminated
NCT03513549
Observational Study Evaluating the Safety of ADASUVEĀ® in Agitation Associated With Schizophrenia or Bipolar I DisorderNot AvailableNot Availableunknown_status
NCT03226522
Addressing Dementia Via Agitation-Centered Evaluationtreatment2 / 3completed
NCT05765162
Safe Brain Initiative, Operationalizing Precision AnaesthesiaNo drug interventionsNot AvailableNot Availablerecruiting
NCT05272501
CAlming Touch for People With Agitation or Other Behavioural Symptoms of DEMentia - A Randomized Feasibility TrialNo drug interventionssupportive_careNot Availablecompleted
NCT06217146
A Medical Cannabis Oil for Treatment of Agitation and Disruptive Behaviors in Subjects With Dementia.treatmentNot Availableterminated
NCT05658510
Dexmedetomidine in the Treatment of Agitation Associated With Schizophrenia and Bipolar Disorder (SERENITY III)treatment3active_not_recruiting
NCT05543681
IGC-AD1 Trial on Agitation in Dementia Due to Alzheimer'sNo drug interventionstreatment2recruiting
NCT01362959
Nicotine Replacement Therapy in the Intensive Care Unittreatment4completed
NCT00122759
Ketamine Sedation in Mechanically Ventilated PatientstreatmentNot Availableunknown_status
NCT00260624
Escitalopram Treatment of Patients With Agitated Dementiatreatment4completed
NCT02256358
Comparison of Effects of Intravenous Midazolam and Ketamine on Emergence AgitationpreventionNot Availablecompleted
NCT04148963
A Study of Staccato Loxapine (ADASUVEĀ®) for Inhalationtreatment3unknown_status
NCT00161473
Alzheimer's in Long-Term Care--Treatment for AgitationtreatmentNot Availablecompleted
NCT02361476
Does Intraoperative Clonidine Reduce Post Operative Agitation in Children?prevention4completed
NCT00723580
Actigraphic Analysis of Treatment Responsehealth_services_researchNot Availablecompleted
NCT01485692
Four Interventions in the Management of Psychomotor Agitation, Safety and Efficacy EvaluationtreatmentNot Availablecompleted
NCT02027844
Cartoon Distraction and Parental Presence on Anxiety in Pediatric AnesthesiaNo drug interventionspreventionNot Availablecompleted
NCT02383004
Acupuncture for the Prevention of Emergence Delirium in Children Undergoing Myringotomy Tube PlacementNo drug interventionspreventionNot Availablecompleted
NCT04959279
ED-TREAT (Early Detection and Treatment to Reduce Events With Agitation Tool) Compared to Usual CareNo drug interventionshealth_services_researchNot Availablenot_yet_recruiting
NCT00122733
Loxapine and Weaning From VentilatortreatmentNot Availablecompleted
NCT01578161
The Effect of Dexmedetomidine on Emergence Agitation in Children Undergoing a Surgery Under Desflurane Anesthesiaprevention4unknown_status
NCT01050478
IMPACT: A Study to Explore the Efficacy and Safety of Paliperidone ER in Patients With Acute Agitationtreatment4completed
NCT02617056
Objective Assessment of Behavioral Associations of Patients With DementiaNo drug interventionsNot AvailableNot Availablerecruiting
NCT00001770
Progestin (Progesterone-Like Hormones) Induced Dysphoria (Depressed Mood, Irritability, Anxiety)No drug interventionsNot AvailableNot Availablecompleted
NCT03216941
Randomised Trial Ketiapine Olanzapine Fast Sedation Agitated Patients Emergency Wardtreatment4completed
NCT01750541
Haloperidol vs. Valproate in Agitationtreatment3completed
NCT02612948
Quetiapine for Delirium Prophylaxis in High-risk Critically Ill Patientstreatment4completed
NCT06556069
Clinical Trial of Peer Support in the ED (PCORI)No drug interventionshealth_services_researchNot Availablenot_yet_recruiting