Stage IV Ovarian Epithelial Cancer (DBCOND0028511)

Identifiers

Synonyms

Ovarian epithelial cancer stage IV / Ovarian cancer metastatic / Ovarian cancer stage IV / Ovarian epithelial cancer metastatic

Associated Data

Indicated Drugs and Targets

Drug	Description	Targets
Bevacizumab	A monoclonal anti-vascular endothelial growth factor antibody used in combination with antineoplastic agents for the treatment of many types of cancer.	Vascular endothelial growth factor A, long formtarget Complement C1q subcomponent subunit Atarget Complement C1q subcomponent subunit Btarget Complement C1q subcomponent subunit Ctarget Low affinity immunoglobulin gamma Fc region receptor III-Atarget Low affinity immunoglobulin gamma Fc region receptor II-atarget Low affinity immunoglobulin gamma Fc region receptor II-btarget Low affinity immunoglobulin gamma Fc region receptor II-ctarget High affinity immunoglobulin gamma Fc receptor Itarget

Clinical Trials

Identifier	Title	Drug(s)	Purpose	Phase	Status
NCT01982487	Vaccine Therapy and IDO1 Inhibitor INCB024360 in Treating Patients With Epithelial Ovarian, Fallopian Tube, or Primary Peritoneal Cancer Who Are in Remission	Epacadostat vCP2292	treatment	1 / 2	withdrawn
NCT00436254	Vaccine Therapy With Sargramostim (GM-CSF) in Treating Patients With Her-2 Positive Stage III-IV Breast Cancer or Ovarian Cancer	Sargramostim	treatment	1	active_not_recruiting
NCT00036751	Imatinib Mesylate in Treating Patients With Stage III or Stage IV Ovarian Epithelial or Primary Peritoneal Cancer	Imatinib	treatment	2	completed
NCT01233505	Veliparib, Oxaliplatin, and Capecitabine in Treating Patients With Advanced Solid Tumors	Capecitabine Oxaliplatin Veliparib	treatment	1	terminated
NCT01558778	Mechanical Stimulation in Preventing Bone Density Loss in Patients Undergoing Donor Stem Cell Transplant	No drug interventions	supportive_care	Not Available	withdrawn
NCT00006942	Bryostatin 1 and Cisplatin in Treating Patients With Advanced Recurrent or Residual Ovarian Epithelial, Fallopian Tube, or Primary Peritoneal Cancer	Bryostatin 1 Cisplatin	treatment	2	completed
NCT00348699	AFP464 in Treating Patients With Metastatic or Refractory Solid Tumors That Cannot Be Removed By Surgery	No drug interventions	treatment	1	completed
NCT00002913	Paclitaxel, Cisplatin, and Topotecan With or Without Filgrastim in Treating Patients With Newly Diagnosed Stage III or Stage IV Epithelial Ovarian Cancer	Cisplatin Filgrastim Paclitaxel Topotecan	treatment	1	completed
NCT00390234	Ziv-aflibercept in Treating Patients With Locally Advanced, Unresectable, or Metastatic Gynecologic Soft Tissue Sarcoma	Aflibercept	treatment	2	completed
NCT00093496	Gemcitabine Hydrochloride and Tanespimycin in Treating Patients With Recurrent Advanced Ovarian Epithelial or Peritoneal Cavity Cancer	Gemcitabine Tanespimycin	treatment	2	completed
NCT00079430	Paclitaxel, Bevacizumab And Adjuvant Intraperitoneal Carboplatin in Treating Patients Who Had Initial Debulking Surgery for Stage II, Stage III, or Stage IV Ovarian Epithelial, Primary Peritoneal, or Fallopian Tube Cancer	Bevacizumab Carboplatin Paclitaxel	treatment	1	completed
NCT00357448	Denileukin Diftitox Used in Treating Patients With Advanced Refractory Ovarian Cancer, Primary Peritoneal Carcinoma, or Epithelial Fallopian Tube Cancer	Denileukin diftitox Human interleukin-2	treatment	1	completed
NCT01846520	Family Caregiver Palliative Care Intervention in Supporting Caregivers of Patients With Stage II-IV Gastrointestinal, Gynecologic, Urologic and Lung Cancers	No drug interventions	supportive_care	Not Available	completed
NCT00081276	3-AP and Cisplatin in Treating Patients With Recurrent or Persistent Platinum-Resistant Ovarian Epithelial or Primary Peritoneal Cancer	Cisplatin Triapine	treatment	2	completed
NCT00089362	Alvespimycin Hydrochloride in Treating Patients With Metastatic or Unresectable Solid Tumors	Alvespimycin	treatment	1	completed
NCT02013492	Propranolol Hydrochloride in Treating Patients With Locally Recurrent or Metastatic Solid Tumors That Cannot Be Removed By Surgery	Propranolol	treatment	0	completed
NCT01159067	Deferasirox for Treating Patients Who Have Undergone Allogeneic Stem Cell Transplant and Have Iron Overload	Deferasirox	supportive_care	2	terminated
NCT00060372	Ipilimumab After Allogeneic Stem Cell Transplant in Treating Patients With Persistent or Progressive Cancer	Ipilimumab Therapeutic allogeneic lymphocytes	treatment	1	completed
NCT00031681	7-Hydroxystaurosporine and Irinotecan Hydrochloride in Treating Patients With Metastatic or Unresectable Solid Tumors or Triple Negative Breast Cancer (Currently Accruing Only Triple-negative Breast Cancer Patients Since 6/8/2007)	7-Hydroxystaurosporine Irinotecan	treatment	1	completed
NCT00408681	Lithium Carbonate in Treating Patients With Acute Intestinal Graft-Versus-Host-Disease (GVHD) After Donor Stem Cell Transplant	Lithium carbonate	supportive_care	Not Available	completed
NCT01322802	Vaccine Therapy in Treating Patients With Stage III-IV or Recurrent Ovarian Cancer	No drug interventions	treatment	1	completed
NCT00059787	Erlotinib Plus Carboplatin and Paclitaxel in Ovarian Carcinoma	Carboplatin Erlotinib Paclitaxel	treatment	2	completed
NCT01536054	Sirolimus and Vaccine Therapy in Treating Patients With Stage II-IV Ovarian Epithelial, Fallopian Tube, or Primary Peritoneal Cavity Cancer	Sargramostim Sirolimus vCP2292	treatment	1	completed
NCT00107445	EF5 in Finding Oxygen in Tumor Cells of Patients Who Are Undergoing Surgery or Biopsy for Cervical, Endometrial, or Ovarian Epithelial Cancer	No drug interventions	diagnostic	2	completed
NCT00030498	Erlotinib in Treating Patients With Solid Tumors and Liver or Kidney Dysfunction	Erlotinib	treatment	1	completed
NCT00335998	Phase I Study of Intravenous Triapine (IND # 68338) in Combination With Pelvic Radiation Therapy With or Without Weekly Intravenous Cisplatin Chemotherapy for Locally Advanced Cervical, Vaginal, or Pelvic Gynecologic Malignancies	Cisplatin Triapine	treatment	1	completed
NCT01927393	Palliative Care in Improving Quality of Life and Symptoms in Patients With Stage III-IV Pancreatic or Ovarian Cancer	No drug interventions	supportive_care	Not Available	withdrawn
NCT02122185	Metformin and Chemotherapy in Treating Patients With Stage III-IV Ovarian, Fallopian Tube, or Primary Peritoneal Cancer	Metformin	treatment	2	active_not_recruiting
NCT00388037	Sunitinib Malate in Treating Patients With Recurrent Ovarian Epithelial, Fallopian Tube, or Primary Peritoneal Cancer	Sunitinib	treatment	2	completed
NCT01079832	Stereotactic Radiosurgery Using CyberKnife in Treating Women With Advanced or Recurrent Gynecological Malignancies	No drug interventions	treatment	2	completed
NCT00022659	Bevacizumab in Treating Patients With Persistent or Recurrent Ovarian Epithelial Cancer or Primary Peritoneal Cancer	Bevacizumab	treatment	2	completed
NCT00126542	Bevacizumab and Erlotinib in Treating Patients With Recurrent or Metastatic Ovarian Epithelial, Fallopian Tube, or Primary Peritoneal Cavity Cancer	Bevacizumab Erlotinib	treatment	2	completed
NCT00085358	Carboplatin and Paclitaxel With or Without Bevacizumab Compared to Docetaxel, Carboplatin, and Paclitaxel in Treating Patients With Stage II, Stage III, or Stage IV Ovarian Epithelial, Fallopian Tube, or Primary Peritoneal Cavity Carcinoma (Cancer)	Bevacizumab Carboplatin Docetaxel Paclitaxel	treatment	1	completed
NCT01155258	Temsirolimus and Vinorelbine Ditartrate in Treating Patients With Unresectable or Metastatic Solid Tumors	Menthol Sirolimus Temsirolimus Vinorelbine	treatment	1	completed
NCT00228358	Cyclophosphamide or Denileukin Diftitox Followed By Expanding a Patient's Own T Cells in the Laboratory in Treating Patients With HER-2/Neu Overexpressing Metastatic Breast Cancer, Ovarian Cancer, or Non-Small Cell Lung Cancer Previously Treated With HER-2/Neu Vaccine	Cyclophosphamide Denileukin diftitox Human interleukin-2	treatment	1	completed
NCT00083122	Cisplatin and Flavopiridol in Treating Patients With Advanced Ovarian Epithelial Cancer or Primary Peritoneal Cancer	Alvocidib Cisplatin	treatment	2	completed
NCT00004074	Interleukin-12 and Trastuzumab in Treating Patients With Cancer That Has High Levels of HER2/Neu	Carboplatin Edodekin alfa Natural Killer Cell Paclitaxel Trastuzumab	treatment	1	completed
NCT00466960	Sargramostim and Paclitaxel Albumin-Stabilized Nanoparticle Formulation in Treating Patients With Advanced Ovarian Cancer, Fallopian Tube Cancer, or Primary Peritoneal Cancer That Did Not Respond to Previous Chemotherapy	Albumin human Albumin-stabilized nanoparticle (130 nm) Paclitaxel Sargramostim	treatment	2	completed
NCT00026091	Fenretinide in Treating Patients With Recurrent or Metastatic Ovarian Epithelial or Primary Peritoneal Cancer	Fenretinide	treatment	2	completed
NCT00087191	EF5 and Motexafin Lutetium in Detecting Tumor Cells in Patients With Abdominal or Non-Small Cell Lung Cancer	Motexafin lutetium	diagnostic	Not Available	terminated
NCT00041080	Tamoxifen Compared With Thalidomide in Treating Women With Ovarian Epithelial Cancer, Fallopian Tube Cancer, or Primary Peritoneal Cancer	Tamoxifen Thalidomide	treatment	3	completed
NCT00182767	Ixabepilone and Liposomal Doxorubicin in Advanced Ovarian Cancer	Doxorubicin Ixabepilone Patupilone	treatment	1 / 2	completed
NCT00795769	Ondansetron in Preventing Nausea and Vomiting in Patients Undergoing Stem Cell Transplant	Ondansetron	supportive_care	2	completed
NCT01126346	Quality of Life and Survivorship Care in Patients Undergoing Hyperthermic Intraperitoneal Chemotherapy (HIPEC)	No drug interventions	supportive_care	Not Available	completed
NCT01494012	Phase I Stereotactic Body Radiation for Metastatic or Recurrent Platinum-Resistant Ovarian Cancer	Fludeoxyglucose (18F) Fludeoxyglucose (18F)	treatment	1	terminated
NCT00063895	Erlotinib in Treating Patients With Advanced Non-Small Cell Lung Cancer, Ovarian Cancer, or Squamous Cell Carcinoma of the Head and Neck	Erlotinib	treatment	1 / 2	completed
NCT00408655	Temsirolimus, Carboplatin, and Paclitaxel in Treating Patients With Advanced Solid Tumors	Carboplatin Menthol Paclitaxel Temsirolimus	treatment	1	completed
NCT01249443	Paclitaxel and Carboplatin in Treating Patients With Metastatic or Recurrent Solid Tumors and HIV Infection	Carboplatin Paclitaxel Vorinostat	treatment	1	terminated