NCT05375825
Phase I Evaluation of Immunotoxin LMB-100 Administered by Normothermic, Intrapleural Perfusion Following Cytoreductive Surgery in Participants With Pleural Mesotheliomas, or Pleural Effusions From Cancers Expressing Mesothelin treatment 1 withdrawn NCT02623959
Indwelling Pleural Catheter With Either Doxycycline or Saline at Day 7 for Pleurodesis treatment 4 terminated NCT00758316
A Prospective, Randomized Controlled Trial for a Rapid Pleurodesis Protocol for the Management of Pleural Effusions No drug interventions treatment 3 completed NCT05543330
A Phase Ib/II Clinical Trial of M701 in the Treatment of Malignant Pleural Effusions Caused by NSCLC treatment 1 / 2 not_yet_recruiting NCT00188474
A Quality of Life Study re Management of Malignant Pleural Effusions No drug interventions Not Available Not Available completed NCT00430664
A Comparative Study of the Safety and Efficacy of Face Talc Slurry and Iodopovidone for Pleurodesis No drug interventions treatment Not Available unknown_status NCT03869697
Study With SCB-313 (Recombinant Human TRAIL-Trimer Fusion Protein) for Treatment of Malignant Pleural Effusions No drug interventions treatment 1 completed NCT02227732
A Pilot Study Evaluating the Safety and Effectiveness of a New Pleural Catheter for the Medical Management of Symptomatic, Recurrent, Malignant Pleural Effusions No drug interventions treatment Not Available completed NCT02092155
Biomarker Levels During Indwelling Pleural cAtheter Sample Testing No drug interventions Not Available Not Available enrolling_by_invitation NCT01997190
Intrapleural AdV-tk Therapy in Patients With Malignant Pleural Effusion treatment 1 completed NCT02975921
Betadine Pleurodesis Via Tunneled Pleural Catheters treatment 4 withdrawn NCT01411202
Effectiveness of Doxycycline for Treating Pleural Effusions Related to Cancer in an Outpatient Population treatment 2 unknown_status NCT02132884
Genetic Sequencing-Informed Targeted Therapy in Treating Patients With Stage IIIB-IV Non-small Cell Lung Cancer No drug interventions treatment Not Available terminated NCT06016179
Tocilizumab Delivered Via Pleural and Peritoneal Catheters in Patients With Advanced Metastatic Cancer treatment 1 recruiting NCT03987087
A Randomized Study of Primary Tumor Radiotherapy for Patients With MPE Stage IV NSCLC No drug interventions treatment 2 unknown_status NCT00528645
AZD0530 in Treating Patients With Extensive Stage Small Cell Lung Cancer treatment 2 completed NCT04235998
Value of Additional Upfront Systematic Lung Ultrasound in the Workup of Patients With Unilateral Pleural Effusion No drug interventions Not Available Not Available completed NCT05130697
A Multicenter Survey Study Into Patient Experience With Mobile Apps No drug interventions Not Available Not Available unknown_status NCT00118183
Docetaxel With Either Cetuximab or Bortezomib as First-Line Therapy in Treating Patients With Stage III or Stage IV Non-Small Cell Lung Cancer treatment 2 completed NCT02054078
Efficacy and Safety of Bevacizumab Versus Pulvis Talci in Malignant Pleural Effusion treatment 2 unknown_status NCT03518788
Malignant Pleural Effusion: Pleur-X vs. Chemical Pleurodesis in VATS No drug interventions treatment Not Available unknown_status NCT04793607
Interventions for Malignant Pleural Effusions Impact on Fatigue No drug interventions Not Available Not Available unknown_status NCT03597009
A Study of Nivolumab and Intrapleural Talimogene Laherparepvec for Malignant Pleural Effusion treatment 1 / 2 terminated NCT00896285
The First Therapeutic Intervention in Malignant Pleural Effusion Trial No drug interventions supportive_care Not Available completed NCT05923515
A Phase I Study of JMKX000197 Injection in the Treatment of Malignant Pleural Effusion No drug interventions treatment 1 recruiting NCT04236037
Ultrasound-guided Biopsy of the Pleura as a Supplement to Extraction of Fluid in Patients With One-sided Fluid in the Pleura No drug interventions diagnostic Not Available terminated NCT02625675
Using Thoracic Ultrasound to Predict Pleurodesis Success in Malignant Pleural Effusions: a Pilot Study No drug interventions Not Available Not Available completed NCT03482570
Activity Behaviours in Patients With Malignant Pleural Effusion No drug interventions Not Available Not Available unknown_status NCT04322136
AMPLE-3: IPC Plus Talc vs VATS in Management of Malignant Pleural Effusion No drug interventions treatment Not Available recruiting NCT05935696
A Prospective Observational Study on the Role of Transthoracic Ultrasound in Differentiating Tuberculous From Malignant Pleural Effusion No drug interventions Not Available Not Available recruiting NCT04123886
A Phase I Study Evaluating SCB-313(Recombinant Human TRAIL-Trimer Fusion Protein) for the Treatment of Malignant Pleural Effusion No drug interventions treatment 1 completed NCT04264325
Quantitative Diaphragmatic Ultrasound Evaluation in Pleural Effusions : A Feasability Study No drug interventions Not Available Not Available completed NCT04985357
Defining the Clinical Potential of Mass Response as a Biomarker for Patient Tumor Sensitivity to Drugs No drug interventions Not Available Not Available not_yet_recruiting NCT03973957
Talc Outpatient Pleurodesis With Indwelling Catheter treatment Not Available unknown_status NCT04039126
Comparison of the Effectiveness of Povidone-Iodine Alone to Povidone-Iodine-Tetracycline Combination treatment 1 unknown_status NCT00313066
Comparison the Level of CTGF Protein and Related Cytokine in Pleural Effusion No drug interventions Not Available Not Available unknown_status NCT05330065
A Study of Intrapleural Administration of Bevacizumab and Camrelizumab for Malignant Pleural Effusion treatment 1 / 2 unknown_status NCT02583282
A Study to Compare the Efficacy and Safety of Intrapleural Doxycycline Versus Iodopovidone for Performing Pleurodesis in Malignant Pleural Effusion No drug interventions supportive_care Not Available completed NCT00637676
Tunneled Pleural Catheter in Partially Entrapped Lung No drug interventions treatment 2 completed NCT02657460
Clinical Trial of Tumor Cell-derived Microparticles Packaging Chemotherapeutic Drugs to Treat Malignant Pleural Effusion treatment 2 unknown_status NCT02649894
Safety and Effectiveness of a New Pleural Catheter for Symptomatic, Recurrent, MPEs Versus Approved Pleural Catheter No drug interventions treatment Not Available completed NCT05620329
UNC Pleural Fluid Registry No drug interventions Not Available Not Available recruiting NCT02191540
Efficacy and Safety Study of Abnoba Viscum F 20mg in Malignant Pleural Effusion Patients No drug interventions treatment 3 completed NCT04806412
Oncodrivers in Malignant Pleural Effusions Associated With Non-small Cell Lung Cancer: A Prospective Study. No drug interventions diagnostic Not Available unknown_status NCT00126581
Erlotinib Hydrochloride With or Without Carboplatin and Paclitaxel in Treating Patients With Stage III-IV Non-small Cell Lung Cancer treatment 2 completed NCT05372055
Malignant Pleural Effusions: Evaluating the psYchosocial Impact of Indwelling Pleural Catheters on Patients No drug interventions Not Available Not Available completed NCT01661790
Intrapleural Bevacizumab and Cisplatin Therapy for Malignant Pleural Effusion Caused by Non-small Cell Lung Cancer treatment 3 completed NCT00564733
FDG-Labeled PET Scan in Planning Chemotherapy in Treating Patients With Stage IIIB or IV Non-Small Cell Lung Cancer treatment 2 completed NCT04914598
A Phase Ⅲ Clinical Study of Combined Cisplatin Versus Placebo Combined With Intracavitary Cisplatin Injection in the Treatment of Malignant Pleural Effusions treatment 3 unknown_status NCT03414905
Management of Malignant Pleural Effusions Using an Indwelling Tunneled Pleural Catheter and Non-Vacuum Collection System No drug interventions Not Available Not Available completed NCT02122185
Metformin and Chemotherapy in Treating Patients With Stage III-IV Ovarian, Fallopian Tube, or Primary Peritoneal Cancer treatment 2 active_not_recruiting NCT02054052
Intrapleural Bevacizumab Injection for Malignant Effusion in Lung Cancer treatment 2 completed NCT05278975
Study of RSO-021 in Patients With Malignant Pleural Effusion Due to Advanced/Metastatic Solid Tumors Including Mesothelioma treatment 1 / 2 recruiting NCT04792970
Randomized Controlled Trial of Talc Instillation In Addition To Daily Drainage Through a Tunneled Pleural Catheter to Improve Rates of Outpatient Pleurodesis in Patients With Malignant Pleural Effusion treatment 4 terminated NCT03235999
The Experiences of Patients Living With Malignant Pleural Effusions No drug interventions Not Available Not Available unknown_status NCT01125124
Safety and Effectiveness Study for Pleurodesis With Silver Nitrate in Malignant Pleural Effusion treatment 2 unknown_status NCT01327235
Endostar and/or Cisplatin for Treatment of Malignant Pleural Effusion or Ascites treatment 2 completed NCT03736122
A Study of Syngenon (BSG-001) for Inhalation in Subjects With Malignant Pleural Effusion and/or Malignant Ascites No drug interventions treatment 1 / 2 unknown_status NCT02429726
Recombinant Adenoviral Human p53 Gene in Treatment of Malignant Pleural Effusion treatment 2 unknown_status NCT05872126
Video Assisted Thoracoscopic Surgery (VATS) - Surgical Pleurodesis vs Tube Drainage in Management of Malignant Pleural Effusion (MPE) No drug interventions treatment Not Available recruiting NCT01854866
Safety and Effectiveness Study of Tumor Cell-derived Microparticles to Treat Malignant Ascites and Pleural Effusion No drug interventions treatment 2 unknown_status NCT00004074
Interleukin-12 and Trastuzumab in Treating Patients With Cancer That Has High Levels of HER2/Neu treatment 1 completed NCT04131231
Safety and Effectiveness of MPCD Therapy on the Treatment of Malignant Pleural Effusion treatment Not Available unknown_status NCT00408460
Imatinib Mesylate and Paclitaxel in Treating Older Patients With Stage IIIB or Stage IV Non-Small Cell Lung Cancer treatment 2 completed NCT01262612
Cediranib as Palliative Treatment in Patients With Symptomatic Malignant Ascites or Pleural Effusion treatment 2 terminated NCT06421610
OPC5: Pressurized IntraThoracic Aerosol Chemotherapy (PITAC) in Patients With Malignant Pleural Effusion. No drug interventions supportive_care 1 recruiting NCT01004510
Zometa Adjuvant Treatment of Malignant Pleural Effusion Due To Non-Small Cell Lung Cancer treatment 2 terminated NCT05565014
Safety and Efficacy Study of Virus Activated Killer Immune Cells (VAK) for Malignant Pleural and Peritoneal Effusion No drug interventions treatment 0 unknown_status NCT03403855
Rocket® Pleural Catheters: QOL, Feasibility and Satisfaction in Recurrent MPE Patients No drug interventions treatment Not Available unknown_status NCT00052338
Bortezomib Plus Gemcitabine and Carboplatin in Treating Patients With Advanced or Recurrent Non-Small Cell Lung Cancer treatment 1 completed NCT02942043
Bevacizumab in the Treatment of Malignant Pleural Effusions of Non-squamous Non-small Cell Lung Cancer treatment 2 unknown_status NCT02674243
Efficacy of Iodopovidone Versus Talc in Palliative Malignant Pleural Effusion treatment 3 completed NCT01612975
The Effect of Non-Steroidal Anti-Inflammatory Drug Naproxen on Pleural Effusion Formation After Lung Resection treatment 2 terminated NCT02045121
Multicentre Study Comparing Indwelling Pleural Catheter With Talc Pleurodesis for Malignant Pleural Effusion Management No drug interventions treatment Not Available unknown_status NCT03394105
Intrapleural Docetaxel Administration Using Medical Pleuroscopy in Malignant Effusion With Lung Cancer treatment 2 completed NCT03272997
The Value of PET-CT in Pleural Effusions No drug interventions Not Available Not Available completed NCT06436807
PMCF Study of the CE-marked Drainova® ArgentiC Catheter No drug interventions Not Available Not Available recruiting NCT03276715
Prognostic Factors on Malignant Pleural Effusion No drug interventions Not Available Not Available completed NCT03270215
The Added Value of CT Scanning in Patients With an Unilateral Pleural Effusion No drug interventions Not Available Not Available completed NCT02702700
Photo-induction as a Means to Improve Cisplatin Delivery to Pleural Malignancies treatment 1 terminated NCT04233359
A Randomised Study Evaluating Diagnostics of Pleural Effusion Among Patients Suspect of Cancer. No drug interventions diagnostic Not Available terminated NCT02517749
Out Patient Talc Slurry Via Indwelling Pleural Catheter for Malignant Pleural Effusion Vs Usual Inpatient Management No drug interventions treatment Not Available completed NCT00099541
Non-small Cell Lung Cancer Registry treatment 4 completed NCT06512896
Clinical Study on Intraluminal Injection of FOLactis No drug interventions treatment Not Available recruiting NCT01670786
Safety Profile of Iodopovidone as an Agent for Pleurodesis in Malignant Pleural Effusion No drug interventions treatment 4 completed NCT03319186
EDIT Management Feasibility Trial No drug interventions treatment Not Available unknown_status NCT05461430
Mass Response of Tumor Cells as a Biomarker for Rapid Therapy Guidance (TraveraRTGx) No drug interventions Not Available Not Available recruiting NCT05693727
Cancer Ratio,Pleural Fluid Adenosine Deaminase,Lactate Dehydrogenase, interferonY, Tumor Necrosis Factor,and Interleukins{2,12,18}for Differentiation Between Malignant and Non Malignant Pleural Effusion No drug interventions Not Available Not Available not_yet_recruiting NCT04670562
Longitudinal Follow up of Patients With Pleural Effusion No drug interventions Not Available Not Available recruiting NCT02805062
Manometry vs Clinical Assessment in the Detection of Trapped Lung in Patients With Suspected Pleural Malignancy No drug interventions Not Available Not Available unknown_status NCT05268172
IFN-γ Combined With T Cells in the Treatment of Refractory Malignant Pleural Effusion and Ascites No drug interventions treatment 1 recruiting NCT02407912
Cisplatin for Malignant Pleural Effusion in Patients With Non-small-cell Lung Cancer treatment Not Available unknown_status NCT05910112
Prospective Data Collection on Clinical, Radiological and Patient Reported Outcomes After Pleural Intervention No drug interventions Not Available Not Available recruiting NCT02825095
Management of Malignant Pleural Effusion - Indwelling Pleural Catheter or Talc Pleurodesis treatment 0 unknown_status NCT04669223
Comparing Different Sizes of Small-bore Chest Drains in Malignant Pleural Effusion No drug interventions treatment Not Available recruiting NCT03781908
Management of Malignant Pleural Effusion With Indwelling Pleural Catheter Versus Silver Nitrate Pleurodesis treatment 1 / 2 unknown_status NCT04749602
Intrapleural Instillation of the Nivolumab in Cancer Patients With Pleural Effusion. treatment 2 completed NCT04254445
Use of Guidance Videos to Increase Engagement and Decrease Anxiety in Patients Undergoing Pleural Tap No drug interventions supportive_care Not Available unknown_status NCT03597828
Respiratory Function of Dexmedetomidine in Patients Undergoing Pleuroscopy No drug interventions Not Available Not Available completed NCT05077111
A Comparative Study Between Regional Anesthesia in Thoracoscopes and the Conventional General Anesthesia No drug interventions supportive_care 4 unknown_status NCT06275178
Medical Thoracoscopy for Diagnosing Unexplained Pleural Effusion: a National Multicenter Retrospective Study No drug interventions Not Available Not Available not_yet_recruiting NCT04684459
Dual-targeting HER2 and PD-L1 CAR-T for Cancers With Pleural or Peritoneal Metastasis No drug interventions treatment 0 recruiting NCT02250118
Intrapleural Bevacizumab After Pleural Drainage in the Context of Breast Cancer treatment 1 terminated NCT00316134
Multiple Biomarkers in Undiagnosed Pleural Effusion No drug interventions Not Available Not Available terminated NCT01819363
Relationship Between Pleural Elastance and Effectiveness of Pleurodesis on Recurrent Malignant Pleural Effusion No drug interventions Not Available Not Available unknown_status NCT00978939
Impact of Aggressive Versus Standard Drainage Regimen Using a Long Term Indwelling Pleural Catheter No drug interventions treatment 4 completed NCT04844827
Pleural Carcinomatosis Tissue Banking No drug interventions Not Available Not Available recruiting NCT03325192
Rapid Pleurodesis Through an Indwelling Pleural Catheter treatment Not Available terminated