Talc

DB09511ApprovedInvestigationalSmall molecule

Talc is a mineral used to prevent recurrence of malignant pleural effusions in symptomatic patients during thoracoscopy or open thoracotomy. Talc is a mineral composed primarily of magnesium, silicon and oxygen.

Mechanism: It has very good absorptive properties.
Curator reviewed
Primary indication: Indicated to prevent recurrence of malignant pleural effusions in symptomatic patients during thoracoscopy or open thoracotomy.Curator reviewed · 4 structured indications
Formula / weight: H₂Mg₃O₁₂Si₄ · 379.259 g/mol (avg)
First approval: Canada, 1970 · United States, 2003
Also known as: E-553(III) · Pulvis Talci · Sterile talc powder · Talc Powder, Sterile · Talcum
Brand names: Sclerosol
Steritalc

Resolves to

Compound

UNII7SEV7J4R1UCAS14807-96-6KEGGD01084

Clinical / RWD

RxNorm10323

Structure

InChIKeyJACYTZHPXAPJCY-UHFFFAOYSA-LSMILES

[O--].[O--].[O--].[O--].[O--].[O--].[O--].[O--].[O--].[O--].[Mg++].[Mg++].[Mg++].[Si+4].[Si+4].[Si+4].[Si+4].[O-][H].[O-][H]

What you can answer from here — as of April 08, 2025

57Drug interactionsStructured to mechanism, not free text

14Clinical trialsPhase, status and sponsor resolved per trial

4Structured indicationsCondition, population, route and combination as fields, not prose

25Marketed productsAcross 2 countries and 18 labellers

2+ReferencesStructured and connected to the statements they support

Which other approved drugs treat the same conditions as Talc, and which companies have late-stage candidates in those indications?

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