NCT06392399
Interventions for the Management of Perineal Cancer Pain No drug interventions treatment Not Available not_yet_recruiting NCT01804790
Efficacy of Neoadjuvant Folfirinox Regimen in Patients With Resectable Locally Advanced Rectal Cancer treatment 3 active_not_recruiting NCT04150705
PET/MR for Rectal Cancer Treatment Monitoring and Surveillance No drug interventions diagnostic Not Available terminated NCT02017509
Immunoscore in Rectal Cancer No drug interventions Not Available Not Available completed NCT00189657
5FU/VL Vs LV5FU2 + CPT11 in Stage II-III Resected Rectal Cancer No drug interventions treatment 3 unknown_status NCT05179837
Endoscopic Optical Coherence Tomography for Screening and Diagnosis of Colorectal Precancerous and Malignant Polyps No drug interventions diagnostic Not Available active_not_recruiting NCT00308516
5-Fluorouracil, Bevacizumab, and Radiation Followed by Modified FOLFOX6 and Bevacizumab in Stage II/III Rectal Cancer treatment 2 completed NCT02641691
Non-Operative Radiation Management of Adenocarcinoma of the Lower Rectum treatment 2 completed NCT03573791
Biomarkers for Predicting Neoadjuvant Chemoradio-resistance for Middle-low Advanced Rectal Cancer No drug interventions Not Available Not Available recruiting NCT05179824
Tempus Priority Study: a Pan-tumor Observational Study No drug interventions Not Available Not Available active_not_recruiting NCT03607643
A Study of the Efficacy of Cannabidiol in Patients With Multiple Myeloma, Glioblastoma Multiforme, and GI Malignancies treatment 1 / 2 unknown_status NCT04319354
Evaluation of cfDNA as a Marker of Response in Rectal Cancer No drug interventions diagnostic Not Available completed NCT01403883
Psychological and Enterostomal Therapy Care No drug interventions prevention Not Available unknown_status NCT03133286
Radiotherapy Assessments During Intervention ANd Treatment (RADIANT) No drug interventions Not Available Not Available completed NCT02948348
Study to Nivolumab Following Preoperative Chemoradiotherapy treatment 1 / 2 unknown_status NCT03452774
SYNERGY-AI: Artificial Intelligence Based Precision Oncology Clinical Trial Matching and Registry No drug interventions Not Available Not Available recruiting NCT03996031
Plan to Thrive: Extending Cancer Survivorship Care Beyond the Clinic No drug interventions Not Available Not Available completed NCT03204994
Fluorescence Targeted Pelvic Lymph Node Mapping treatment 1 / 2 terminated NCT06181201
Association Between the Composition of the Intestinal Microbiota and Tumor Response in Locally Advanced Rectal Cancer No drug interventions Not Available Not Available active_not_recruiting NCT04716010
Developing and Evaluating Product Messaging No drug interventions prevention Not Available completed NCT04160650
Educational Nursing Intervention Among Patients With Colorectal Cancer During Chemotherapy No drug interventions supportive_care Not Available completed NCT04812743
Colorectal Health Research Champions No drug interventions prevention Not Available terminated NCT04456283
Survival of Patients With a Reduction in the Number of Lymph Nodes in Rectal Cancer After Neoadjuvant Chemoradiotherapy No drug interventions Not Available Not Available unknown_status NCT04095299
Standard Dose Versus High Dose of Radiotherapy in Rectal Preservation With Chemo-radiotherapy in Rectal Cancer Patients treatment 2 recruiting NCT03896958
The PIONEER Initiative: Precision Insights On N-of-1 Ex Vivo Effectiveness Research Based on Individual Tumor Ownership (Precision Oncology) No drug interventions Not Available Not Available unknown_status NCT00271986
Peritoneal Microdialysis in Patients Undergoing Low Anterior Resection (LAR) for Recto-sigmoid Cancer No drug interventions Not Available Not Available completed NCT05887531
Abdominopelvic Cancer Prehabilitation No drug interventions supportive_care Not Available recruiting NCT05732389
Immunotherapy in Patients With Early dMMR Rectal Cancer treatment 2 recruiting NCT05358704
Preoperative ChemoRadiation And FOLFOXIRI for Rectal Cancer (CRAFTER) for Rectal Cancer treatment 2 recruiting NCT04880772
Clinical Trial Comparing Standard Care Versus Prehabilitation in Patients Undergoing Cancer Surgery No drug interventions treatment Not Available completed NCT01146769
Early Pelvic Floor Muscle Training Improves Pelvic Floor Muscle Strength in Patient After Low Anterior Resection No drug interventions treatment Not Available unknown_status NCT03910283
Leveraging Mindsets to Improve Health & Wellbeing in Patients With Cancer No drug interventions supportive_care Not Available not_yet_recruiting NCT04139967
Study of Short Course Radiation Therapy for Elderly Patients With Rectal Cancer No drug interventions treatment Not Available terminated NCT06236633
Safety & Efficacy of Ischemic Preconditioning by Embolization of the Inferior Mesenteric Artery in Surgery for Tumors of Lower and Middle Rectum No drug interventions treatment Not Available recruiting NCT04401787
Converted Laparoscopic Resection of Upper Rectal Carcinoma T1-4 N0-1 in Obese Patients. No drug interventions treatment Not Available completed NCT02533271
Optimization of Preoperative Treatment in Locally Advanced Rectal Cancer No drug interventions treatment 3 recruiting NCT05667259
Prognostic Significance of Lymph Node Ratio in Rectal Cancer on Overall Survival No drug interventions Not Available Not Available completed NCT05154474
Assessment of Sarcopenia at Diagnosis for Patients With Previously Untreated Metastatic Cancer or Hematologic Malignancy No drug interventions Not Available Not Available unknown_status NCT03688906
AI-EMERGE: Development and Validation of a Multi-analyte, Blood-based Colorectal Cancer Screening Test No drug interventions Not Available Not Available completed NCT03628248
Effect of Endovascular Inferior Mesenteric Artery Embolization on Colonic Perfusion Prior to Rectal Surgery for Rectal Tumor or Sigmoid Colon Surgery No drug interventions other Not Available completed NCT04790227
MRI for Selection of Complete Responders After Chemoradiation for Locally Advanced Rectal Cancer No drug interventions Not Available Not Available unknown_status NCT05646043
PREHAB - Improving Condition Before Surgery No drug interventions supportive_care Not Available recruiting NCT04679597
Total Neoadjuvant Therapy Versus Standard Therapy of Locally Advanced Rectal Cancer With High Risk Factors for Failure Not Available Not Available completed NCT05009069
A Study of Atezolizumab With or Without Tiragolumab Following Neoadjuvant Chemoradiotherapy in Participants With Locally Advanced Rectal Cancer treatment 2 active_not_recruiting NCT05985239
Virtual Ileostomy Versus Diverting Ileostomy No drug interventions Not Available Not Available completed NCT06633133
Virtual Ileostomy Versus Diverting Ileostomy in Patients Undergoing Total Mesorectal Excision No drug interventions prevention Not Available recruiting NCT06637462
A Study of Response to Standard Treatment Before Surgery in People With Rectal Cancer No drug interventions diagnostic Not Available recruiting NCT06608537
A Clinical Study Based on FAPI-PET/CT Technology to Predict Pathological Complete Response After Neoadjuvant Chemoradiotherapy for MSS Rectal Cancer diagnostic 2 not_yet_recruiting NCT06628674
Developing and Testing the Effect of Online Interactive Videos in Improving Low Anterior Resection Syndrome. No drug interventions supportive_care Not Available not_yet_recruiting NCT06631443
Asian Watch-and-Wait Database (AWWD) No drug interventions Not Available Not Available not_yet_recruiting NCT03259035
NEO: Neoadjuvant Chemotherapy, Excision and Observation for Early Rectal Cancer No drug interventions treatment 2 completed NCT06328361
Nordic ORgan Preservation Pilot Approach Nonrandomised Single-Arm Trial for Non-Operative Management of Rectal Cancer No drug interventions treatment Not Available recruiting NCT03190941
Administering Peripheral Blood Lymphocytes Transduced With a Murine T-Cell Receptor Recognizing the G12V Variant of Mutated RAS in HLA-A*11:01 Patients treatment 1 / 2 recruiting NCT03745326
Administering Peripheral Blood Lymphocytes Transduced With a Murine T-Cell Receptor Recognizing the G12D Variant of Mutated RAS in HLA-A*11:01 Patients treatment 1 / 2 recruiting NCT03853733
Hypofractionated Palliative Radiotherapy in Patients With Advanced Non-operable Rectal Cancer No drug interventions Not Available Not Available recruiting NCT05024097
A Phase I-II Study to Test the Safety and Efficacy of PD1 (AB122) and Adenosine Receptor (AB928) Antagonists With Chemotherapy After Short-Course Radiation for Rectal Cancer. treatment 2 recruiting NCT06241703
Effect of ICCAUT Strategy on Postoperative Urinary Dysfunction After Radical Rectal Cancer Surgery No drug interventions treatment Not Available recruiting NCT05964530
Radical vs Local Excision for Rectal Cancer With Clinically Complete Remission No drug interventions treatment Not Available recruiting NCT06205485
Neoadjuvant Chemotherapy, Excision And Observation vs Chemoradiotherapy For Rectal Cancer treatment 3 recruiting NCT06337552
High-Fermented Food Intervention Among Locally Advanced Rectal Cancer Patients (The FEED Trial) No drug interventions supportive_care Not Available recruiting NCT06613399
Multi-Technology Integrated Total Mesorectal Excision Versus Conventional Total Mesorectal Excision for the Treatment of Middle and Distal Rectal Cancer. No drug interventions treatment Not Available not_yet_recruiting NCT06589388
ctDNA Monitoring to Predict the Efficacy of TNT for Rectal Cancer No drug interventions Not Available Not Available recruiting NCT06616870
Study of the Predictive and Prognostic Role of Pharmacogenetic and Radiogenic Variants on the Response to Neoadjuvant Chemoradiation Therapy in Patients With Locally Advanced Rectal Cancer No drug interventions Not Available Not Available not_yet_recruiting NCT06599827
Neoadjuvant Moderately Hypofractionated Radiotherapy Combined with Chemotherapy and Immunotherapy for High-risk LARC No drug interventions treatment 2 not_yet_recruiting NCT04443543
An Adaptive-design Prospective Cohort Study of Watch and Wait Strategy in Patients With Locally Advanced Rectal Cancer treatment 2 not_yet_recruiting NCT01507103
Tecemotide (L-BLP25) in Rectal Cancer treatment 2 completed NCT01781403
Preoperative CRT With Temozolomide Plus Capecitabine in Rectal Cancer treatment 1 completed NCT02532803
Mri IN STaging REctal Polyp Planes No drug interventions diagnostic Not Available unknown_status NCT04939103
TRUS-FNA For The Prediction Of pCR After Neoadjuvant Treatment In Rectal Cancer No drug interventions Not Available Not Available completed NCT03068403
Dynamic Contrast Enhanced Ultrasound for Predict and Assess Rectal Cancer Response After Neo-adjuvant Chemoradiation - RECT No drug interventions other Not Available completed NCT03245203
A Pilot Study of Neoadjuvant Chemotherapy Combined With Bevacizumab for Locally Advanced Rectal Cancer No drug interventions treatment Not Available unknown_status NCT04991090
Management of LLN Metastasis in Locally Advanced Rectal Cancer: A Prospective Radiation Dose Escalation Study No drug interventions treatment Not Available recruiting NCT06006390
CEA Targeting Chimeric Antigen Receptor T Lymphocytes (CAR-T) in the Treatment of CEA Positive Advanced Solid Tumors No drug interventions treatment 1 / 2 recruiting NCT01152164
Quality of Life in Patients After Combined Modality Treatment of Rectal Cancer No drug interventions Not Available Not Available unknown_status NCT00587964
Phase II Trial of Stereotactic Radiosurgery Boost Following Surgical Resection for Brain Metastases No drug interventions treatment 2 completed NCT04591821
Bowel Dysfunction 3 Years After Anterior Resection a in a Swedish National Cohort No drug interventions Not Available Not Available completed NCT04087421
Comparison of Transanal Irrigation and Glycerol Suppositories in Treatment of Low Anterior Resection Syndrome treatment 3 recruiting NCT06254521
The Effects of Neoadjuvant Tislelizumab Combined With Chemotherapy in Locally Advanced MSS Rectal Cancer treatment 2 recruiting NCT04573621
Pelvic Drain After Rectal Resection for Mid-low Rectal Cancer No drug interventions prevention Not Available unknown_status NCT04730102
Rectal Washout in Transanal Total Mesorectal Excision and Presence of Intraluminal Malignant Cells No drug interventions Not Available Not Available completed NCT04336202
Watch and Wait Management on Rectal Cancer Patients Using New Swift Local Therapy No drug interventions treatment Not Available recruiting NCT00689702
Cetuximab (Erbitux®), Capecitabine and Radiotherapy in Neoadjuvant Treatment of Patients With Rectal Cancer treatment 2 unknown_status NCT02312284
Observational Study on the Patients With Rectal Cancer No drug interventions Not Available Not Available completed NCT04065984
Body Composition Manipulation in CoLorectal cancEr (BiCyCLE): Neuromuscular Electrical Stimulation (NMES) No drug interventions treatment Not Available active_not_recruiting NCT05807984
Re-irradiation Therapy of Locally Recurrent Rectal Cancer With Carbon Ion No drug interventions treatment 2 not_yet_recruiting NCT05927584
Local Excision for Organ Preservation in Early REctal Cancer With No Adjuvant Treatment No drug interventions Not Available Not Available recruiting NCT02113384
Locally Advanced Rectal Cancer - Exfoliated Peritoneal Tumor Cells No drug interventions Not Available Not Available active_not_recruiting NCT04558684
Radiotherapy With Neoadjuvant Chemotherapy and Immunotherapy in Rectal Cancer No drug interventions treatment 1 / 2 suspended NCT03182179
Efficacy of Ondansetron in LARS Treatment treatment Not Available completed NCT06255379
Study of Fruquintinib Combined With Tegafur Gimeracil Oteracil in Patients With Metastatic Colorectal Cancer treatment 2 not_yet_recruiting NCT04224779
Liquid Biopsies and IMAging for Improved Cancer Care No drug interventions diagnostic Not Available recruiting NCT04896879
Experiences and Needs of Patients, Their Informal Caregiver and Healthcare Professionals Regarding LARS No drug interventions Not Available Not Available completed NCT00579579
Functional Outcomes and Quality of Life in Patients Undergoing Surgery for Rectal Cancer No drug interventions Not Available Not Available completed NCT00808379
Concurrent Chemo-Radiotherapy Versus Radiotherapy With Boost in Locally Advanced Unresectable Rectal Cancers No drug interventions treatment 2 unknown_status NCT03602079
Study of A166 in Patients With Relapsed/Refractory Cancers Expressing HER2 Antigen or Having Amplified HER2 Gene No drug interventions treatment 1 / 2 completed NCT01226979
Study of High-Dose-Rate Endorectal Brachytherapy (HDRBT) in the Treatment of Locally Advanced Low Rectal Cancer No drug interventions treatment Not Available completed NCT04907643
Virtual Reality for GI Cancer Pain to Improve Patient Reported Outcomes No drug interventions supportive_care Not Available recruiting NCT04036643
Rectal Cancer Response Hybrid Imaging Assessement No drug interventions diagnostic Not Available unknown_status NCT05233787
Trial Evaluating the Tailored Versus the Systematic Use of Defunctioning Stoma After Total Mesorectal Excision for Rectal Cancer (GRECCAR17) No drug interventions treatment Not Available recruiting NCT03242187
Trans-anal Versus Laparoscopic TME for Mid and Low Rectal Cancer No drug interventions treatment 2 / 3 unknown_status NCT00176787
Radiation Therapy With Capecitabine in Rectal Cancer treatment 2 terminated NCT05279287
Video Analysis of Errors and Technical Performance Within Minimally Invasive Surgery Short Title: Video Analysis in Minimally Invasive Surgery (VAMIS) No drug interventions Not Available Not Available recruiting NCT01474187
Genotype-driven Phase I Study of Irinotecan Administered in Neoadjuvant Chemoradiotherapy in Patients With Stage II/III Rectal Cancer treatment 1 unknown_status NCT00532987
Assessment of Health Related Quality of Life in Patients Treated for Rectal Cancer No drug interventions Not Available Not Available terminated NCT03729687
Short Course Radiation Therapy Followed by Pre-operative Chemotherapy and Surgery in High-risk Rectal Cancer treatment 2 active_not_recruiting NCT02830633
Trial to Evaluate Laparoscopy-assisted Nerve-preserved Total Mesorectal Excision (LNTME) Versus Open TME for Rectal Cancer No drug interventions treatment 2 unknown_status NCT06035133
Treatment of Low Locally Advanced Rectal Cancer With Radiotherapy Removal TNT Plus Neoadjuvant Therapy treatment Not Available not_yet_recruiting NCT05688033
Dosimetric Limitation of Pelvic Bone and Peritoneal Space in Rectal Cancer Patients During Chemoradiotherapy No drug interventions treatment Not Available active_not_recruiting NCT05502354
CRP-guided Transanal Drainage Removal After Rectal Surgery No drug interventions prevention Not Available recruiting NCT05793554
CLASSICA: Validating AI in Classifying Cancer in Real-Time Surgery Study 1 No drug interventions Not Available Not Available not_yet_recruiting NCT03731754
"Cross" Closure for Reconstructing the Perineal Wound of Abdominoperineal Resection No drug interventions treatment Not Available unknown_status NCT05293054
Healing of Rectal Anastomosis Sealed With a Concentrate Derived From the Patient's Blood, After Rectal Cancer Surgery No drug interventions Not Available Not Available completed NCT04747951
Total Neoadjuvant Therapy in Rectal Cancer Treatment No drug interventions treatment 4 unknown_status NCT01670851
Perineal Reconstruction Following eLAPE and Simultaneous Stoma Sublay Reinforcement No drug interventions Not Available Not Available completed NCT04273451
RadioPathomics Artificial Intelligence Model to Predict Tumor Regression Grading in Locally Advanced Rectal Cancer No drug interventions Not Available Not Available unknown_status NCT00625651
Phase 1b/2 Study of AMG 655 With mFOLFOX6 and Bevacizumab for First-Line Metastatic Colorectal Cancer treatment 1 / 2 completed NCT00712751
The Sexual Health of Rectal Cancer Patients No drug interventions Not Available Not Available active_not_recruiting NCT00220051
A Phase II Study of Oxaliplatin Capecitabine and Pre-operative Radiotherapy for Patients With Locally Advanced and Inoperable Rectal Cancer treatment 2 completed NCT02498353
Comparing Preoperative Short-course Radiotherapy With or Without Local Boost for Rectal Cancer No drug interventions treatment Not Available unknown_status NCT04922853
Comparison of the Pathological Effect Between 2 and 4 Cycles Neoadjuvant CAPOX for Low/Intermediate Risk II/III Rectal Cancer No drug interventions treatment 3 recruiting NCT04369053
Prevention of Colorectal Cancer Through Multiomics Blood Testing No drug interventions Not Available Not Available active_not_recruiting NCT05108753
Short-term Outcomes of Transanal Total Mesorectal Excision With Structured Training Curriculums in China No drug interventions Not Available Not Available completed NCT04172753
Feasibility of Online MR-guided Radiotherapy on a 1.5T MR-Linac No drug interventions treatment Not Available recruiting NCT01902953
Lymphoseek® as Lymphoid Tissue Targeting Agents in Colon Cancer(CNC) diagnostic 2 completed NCT01511653
Validation of Colon Biomarkers for the Early Detection of Colorectal Adenocarcinoma No drug interventions Not Available Not Available completed NCT00651677
Hand Assisted Versus "Pure" Laparoscopic Assisted Proctectomy for Rectal Cancer No drug interventions treatment Not Available withdrawn NCT01560377
Perfusion Assessment in Laparoscopic Left Anterior Resection No drug interventions supportive_care 1 completed NCT01443377
Neoadjuvant Radiochemotherapy Combined With Panitumumab in Locally Advanced KRAS Wild-type Rectal Cancer treatment 2 completed NCT04273477
Radiomics-based Artificial Intelligence System to Predict Neoadjuvant Treatment Response in Rectal Cancer No drug interventions Not Available Not Available unknown_status NCT05056077
Improving Nutrition and Physical Activity for Cancer Survivors (Tools To Be Fit) No drug interventions supportive_care Not Available recruiting NCT03102047
Study of Durvalumab (MEDI4736) After Chemo-Radiation for Microsatellite Stable Stage II-IV Rectal Cancer treatment 2 completed NCT02649647
Proximally Extended Resection for Rectal Cancer After Neoadjuvant Chemoradiotherapy No drug interventions treatment Not Available recruiting NCT01434147
Preoperative Combined Induction Chemotherapy With Capecitabine, Oxaliplatin, Bevacizumab and Radiotherapy treatment 2 completed NCT04717947
Interval Between Neoadjuvant Therapy and Surgery in the Treatment of Locally Advanced Rectal Cancer (CRONOS) No drug interventions Not Available Not Available unknown_status NCT03009747
A Prospective Multi-Center Research on Bowel Dysfunction After Sphincter Preservative Surgery No drug interventions Not Available Not Available unknown_status NCT01347645
Irinotecan Plus E7820 Versus FOLFIRI in Second-Line Therapy in Patients With Locally Advanced or Metastatic Colon or Rectal Cancer treatment 1 / 2 terminated NCT06304545
Treatment of Rectal Cancer With Long-term Concurrent Chemoradiotherapy Combined With Camrelizumab treatment 2 not_yet_recruiting NCT05445245
The Longitudinal Study of Low Anterior Resection Syndrome in Patients With Newly Diagnosed Rectal Cancer. No drug interventions Not Available Not Available active_not_recruiting NCT01488045
Compare Propofol to Fentanyl and Midazolam for Colonoscopy supportive_care Not Available completed NCT02569645
Rosuvastatin in the Treatment of Rectal Cancer treatment 2 completed NCT02127645
Neoadjuvant Radiotherapy Followed by Transanal Endoscopic Microsurgery for T1-T2 Extraperitoneal Rectal Cancer No drug interventions treatment 3 completed NCT00671645
Preoperative Combined RadioChemo-Molecular Target Therapy With Capecitabine, Bevacizumab, and Radiotherapy treatment 2 terminated NCT04455945
Quality of Life After Rectal Cancer Surgery No drug interventions Not Available Not Available completed NCT05390398
Study on Fatigue in Colorectal Cancer Survivors, a Lifestyle Intervention No drug interventions treatment Not Available active_not_recruiting NCT02752698
Domestic Surgical Robot Clinical Study No drug interventions other Not Available unknown_status NCT03171298
Laparoscopic Assisted Transanal Resection of Rectal Cancer With Total Mesorectal Excision No drug interventions treatment Not Available unknown_status NCT01013805
Preoperative Radiotherapy and Chemotherapy in Patients With Locally Advanced Rectal Cancer treatment 2 completed NCT02403505
Early Phase Clinical Trial About Therapeutic Biological Product Mix for Treating CEA Positive Rectal Cancer health_services_research 1 active_not_recruiting NCT01186705
Clinical And Translational Study Of MK-2206 In Patients With Metastatic KRAS-Wild-Type, PIK3CA-Mutated, Colorectal Cancer treatment 2 terminated NCT01397305
An Extended Feasibility Phase I/II Study of Methylenetetrahydrofolate (Arfolitixorin) and Pemetrexed Single Agent, Given as Neoadjuvant Treatment in Patients With Resectable Rectal Cancer treatment 1 / 2 completed NCT04103697
Neoadjuvant Chemotherapy in Patients With Intermediate Risk Upper and Mid Rectal Cancer treatment 3 unknown_status NCT01347697
Collagen Implant (Biological Mesh) Versus GM Flap for Reconstruction of Pelvic Floor After ELAPE in Rectal Cancer No drug interventions treatment Not Available active_not_recruiting NCT01927497
Biological Mesh Closure of the Pelvic Floor After Extralevator Abdomino Perineal Resection for Rectal Cancer No drug interventions treatment 3 completed NCT05000697
Chemoradiation and Consolidation Chemotherapy With or Without Oxaliplatin for Distal Rectal Cancer and Watch and Wait treatment Not Available recruiting NCT05674097
Blood Flow Path Reconstruction in Rectal Cancer No drug interventions Not Available Not Available completed NCT06369597
A Randomized Controlled Trial of the Safety and Efficacy of Robotic Telesurgery Versus Laparoscopic Surgery No drug interventions treatment Not Available not_yet_recruiting NCT04683783
National Registry of Liver First Approach No drug interventions Not Available Not Available completed NCT04963283
Study of Cabozantinib and Nivolumab in Refractory Metastatic Microsatellite Stable (MSS) Colorectal Cancer treatment 2 active_not_recruiting NCT00254683
Use of Positron Emission Tomography/Computed Tomography (PET/CT) to Assess Tumor Response to Neoadjuvant Treatment for Distal Rectal Cancer No drug interventions diagnostic 2 unknown_status NCT03548961
Organ Preservation in Early Rectal Cancer Patients No drug interventions treatment 2 suspended NCT04527861
Oncologic Outcomes of Single-incision Versus Conventional Laparoscopic Surgery for Colorectal Cancer No drug interventions treatment Not Available recruiting NCT03876561
"Impact of Pelvic Floor Prehabilitation Using Biofeedback on the Severity of the Low Anterior Resection Syndrome in Patients Undergoing a Total Mesorectal Excision for Rectal Cancer" No drug interventions treatment Not Available unknown_status NCT03074461
Transverse Coloplasty vs. Side-to-end Anastomosis Following Low Anterior Resection (LAR): CSAR Trial No drug interventions treatment Not Available unknown_status NCT03750461
Stoma Closure and Reinforcement Trial No drug interventions prevention Not Available completed NCT00297128
Preoperative Chemoradiation With Capecitabine and Cetuximab treatment 2 completed NCT00585728
CT Virtual Proctoscopy for Staging and Volume Assessment for Rectal Cancer No drug interventions diagnostic Not Available completed NCT02812628
Conventional Laparoscopic APR Versus Laparoscopic APR With Transabdominal Individualized Levator Transection No drug interventions treatment Not Available unknown_status NCT01125111
The Clinical Study of Making the Evidence With Application of Da Vinci-Robot Assisted Low Anterior Resection in Rectal Cancer No drug interventions Not Available Not Available completed NCT03574493
Rectal Surgery Evaluation Trial (RESET) No drug interventions Not Available Not Available active_not_recruiting NCT06096493
Prognostic Factors Affecting Recurrence and Disease-Free Survival After Surgical Resection for Cancer Rectum No drug interventions Not Available Not Available recruiting NCT01589471
The Value of Botox-A for Management of Low Anterior Resection Syndrome treatment 2 completed NCT05243771
Norwegian Stoma Trial No drug interventions Not Available Not Available recruiting NCT05651971
The Anatomical Localization of the Inferior Mesenteric Artery in Relation to the Left Colonic Artery No drug interventions Not Available Not Available recruiting NCT01865071
Early Closure of Temporary Loop Ileostomy After Rectal Resection for Cancer No drug interventions treatment Not Available unknown_status NCT02279771
Transanal Reinforcement of Low Rectal Anastomosis in Rectal Cancer Surgery No drug interventions treatment Not Available unknown_status NCT06507371
Node-sparing Short-Course Radiation Combined With CAPOX and Tislelizumab for MSS Rectal Cancer treatment 3 recruiting NCT02585271
Transanal Decompression Tube Versus Stent for Acute Malignant Left-sided Colonic and Rectal Obstruction No drug interventions treatment Not Available terminated NCT02288078
Oral Steroids for Regorafenib-induced Fatigue/Malaise in Unresectable mCRC (KSCC1402/HGCSG1402) treatment 2 unknown_status NCT02046278
LifeSeal™ Pilot Study in Subjects Undergoing Circular Stapled Anastomosis Created Within 10 cm of the Anal Verge No drug interventions treatment Not Available completed NCT03520088
PROSPECTIVE CONTROLLED AND RANDOMIZED STUDY OF THE GENITOURINARY FUNCTION AFTER RECTAL CANCER SURGERY IN RELATION TO THE DISSECTION OF THE INFERIOR MESENTERIC VESSELS No drug interventions prevention Not Available unknown_status NCT03962088
Timisnar - Biomarkers Substudy (Timisnar-mirna) No drug interventions Not Available Not Available recruiting NCT04495088
Preoperative FOLFOX Versus Postoperative Risk-adapted Chemotherapy in Patients With Locally Advanced Rectal Cancer treatment 3 recruiting NCT06542588
Short-Course Radiotherapy Followed by Neoadjuvant Chemotherapy, HLX07and Serplulimab in LARC treatment 2 active_not_recruiting NCT04928807
Short-Course Radiotherapy Followed by Neoadjuvant Chemotherapy and Camrelizumab in Locally Advanced Rectal Cancer (UNION) treatment 3 active_not_recruiting NCT04999007
Artificial Intelligence Assists Surgeons' Decision Making No drug interventions diagnostic Not Available recruiting NCT02205307
A Study Assessing Perfusion Outcomes With PINPOINT® Near Infrared Fluorescence Imaging in Low Anterior Resection No drug interventions treatment Not Available terminated NCT01887509
Evaluation of Rectal Tumor Margin Using Confocal Endomicroscopy and Comparison to Histopathology No drug interventions diagnostic Not Available terminated NCT01706809
Comparing of Different Biomarkers From Vena Rectalis Superior and Vena Cubiti in Patients Undergoing Low Anterior Resection for Rectum Cancer No drug interventions Not Available Not Available unknown_status NCT02935309
Capecitabine and Lenvatinib With External Radiation in Rectal Adenocarcinoma treatment 1 completed NCT02490709
Local Excision of Clinical T3 Rectal Adenocarcinoma Showing Major Response(ycT0-1) After Neoadjuvant Chemoradiotherapy No drug interventions treatment 2 unknown_status NCT03879109
Chemotherapy Followed by Pelvic Reirradiation Versus Chemotherapy Alone as Pre-operative Treatment for Locally Recurrent Rectal Cancer No drug interventions treatment 3 active_not_recruiting NCT00094809
Chemotherapy Administered Every 2 Weeks With or Without Pegfilgrastim in Subjects With Advanced or Metastatic Colon Cancer supportive_care 2 completed NCT04534309
Behavioral Weight Loss Program for Cancer Survivors in Maryland No drug interventions prevention Not Available completed NCT04392609
Predicting Locally Advanced Rectal Cancer Response to NCT and NCRT With MRI No drug interventions Not Available Not Available unknown_status NCT01749956
5-FU, Aflibercept, and Radiation (RT) for Preoperative and Postoperative Patients With Stage II/III Rectal Cancer treatment 2 completed NCT03601156
Preoperative Intraarterial Chemoembolization Combined With Radiotherpy in Locally Advanced Rectal Cancer No drug interventions treatment Not Available unknown_status NCT02190656
Anterior Resection Syndrome Following Sphincter-preserving Surgery No drug interventions Not Available Not Available completed NCT04804956
Mesorectal Microbiome as a Prognostic Factor in Patients With Rectal Cancer No drug interventions Not Available Not Available recruiting NCT01148056
Intensity Modulated Radiation Therapy (IMRT) for Patients With Rectal Cancer No drug interventions treatment 2 terminated NCT03038256
Effect of Concurrent Capecitabine-based Long-term Radiotherapy Followed by XELOX Plus TME in Patients With High Risk Rectal Cancer: a Multi-centers, Randomized Controlled, Open-Label Trial treatment 2 recruiting NCT02437656
Combination of Metformin to Neoadjuvant Radiochemotherapy in the Treatment of Locally Advanced Rectal Cancer (METCAP). treatment 2 completed NCT02163785
Abdominoperineal Extra-Elevators Rectal Resection for Cancer: Prone Position vs. Supine Position No drug interventions treatment Not Available terminated NCT05984485
The Efficacy of Primary Total Mesorectal Excision (TME) Surgery Versus Neoadjuvant Chemotherapy Combined With TME Surgery in Low-risk Locally Advanced Rectal Cancer No drug interventions treatment 3 recruiting NCT01755585
Irradiation Modulates the Pharmacokinetics of Anticancer Drugs No drug interventions Not Available Not Available unknown_status NCT00394615
Metabolic Imaging Predict Histopathologic Response to Preop ChemoXRT for Locally Advanced Rectal CA No drug interventions treatment Not Available terminated NCT05078515
Multicenter Validation of the PREDICT Score No drug interventions Not Available Not Available completed NCT00581815
Spectroscopy With Surface Coils and Decoupling No drug interventions diagnostic 1 completed NCT06395337
Multimodal Imaging in Rectal Cancer & Pancreatic Cancer No drug interventions other 1 / 2 not_yet_recruiting NCT05027737
Early Ileostomy Closure for Rectal Cancer Patients in North America No drug interventions treatment Not Available recruiting NCT03881332
Measurement of Perioperative Glomerular Filtration Rate No drug interventions Not Available Not Available completed NCT00503932
Proton Therapy With Capecitabine for Rectal Cancer treatment 1 / 2 withdrawn NCT02421432
Evaluation of the Safety and the Efficacy of Transanal TME in Difficult Cases No drug interventions treatment Not Available unknown_status NCT02022852
Neoadjuvant Sequential Therapy in Locally Advanced Mid/Low Rectal Cancer treatment 2 unknown_status NCT04231552
Preoperative Short Course Radiotherapy With Chemotherapy and Camerelizumab in Locally Advanced Rectal Cancer treatment 1 / 2 unknown_status NCT03671252
Prospectively Randomized Control Clinical Trial of FOLFOXIRI Preoperative Chemotherapy Alone on Rectal Cancer in Local Advance Comparing to Oral Capecitabine Combined With Long-term Radiation No drug interventions treatment 3 recruiting NCT05551052
CRC Detection Reliable Assessment With Blood No drug interventions Not Available Not Available active_not_recruiting NCT06565052
The Impact of PReOPerative Exercise and NutritionaL Optimization on Perioperative Outcomes for Patients Undergoing Treatment for Rectal Cancer: The PROPEL Trial No drug interventions supportive_care Not Available not_yet_recruiting NCT02810652
Perioperative Geriatrics Intervention for Older Cancer Patients Undergoing Surgical Resection No drug interventions supportive_care Not Available completed NCT01544452
Total Preoperative MR Diagnostic Evaluation Versus Standard Diagnostic Evaluation in Patients With Rectal Cancer No drug interventions diagnostic Not Available terminated NCT02861300
CB-839 + Capecitabine in Solid Tumors and Fluoropyrimidine Resistant PIK3CA Mutant Colorectal Cancer treatment 1 / 2 active_not_recruiting NCT01129700
Short-course Preoperative Chemoradiotherapy Followed by Delayed Operation for Locally Advanced Rectal Cancer No drug interventions treatment 2 completed NCT01045200
Nurse-or Surgeon-led Follow-up After Rectal Cancer No drug interventions Not Available Not Available completed NCT01801059
Patient Activation Intervention in Improving Screening Rates for Colorectal Cancer No drug interventions screening Not Available completed NCT03874559
Exosomes in Rectal Cancer No drug interventions Not Available Not Available unknown_status NCT03351959
Complete Pathologic Response Rectal Cancers No drug interventions Not Available Not Available unknown_status NCT06435975
Physical Activity in Rectal Cancer Survivors No drug interventions treatment Not Available completed NCT06504875
Application of PD-1 Monoclonal Antibody in Combination With IL-2 and CapeOX in Organ Preservation Therapy for Ultra-Low Localized Advanced Rectal Cancer Not Available Not Available not_yet_recruiting NCT06160570
IMRT Versus 3DCRT for Locally Advanced Rectal Cancer, Prospective Phase II Study. No drug interventions treatment Not Available completed NCT00752570
A Phase 2, Randomized, Double Blind, Placebo Controlled Study of AMG 386 in Combination With FOLFIRI in Subjects With Previously Treated Metastatic Colorectal Carcinoma treatment 2 completed NCT02280070
RP II Study of SOX vs mFOLFOX6 in Patients With Resectable Rectal Cancer (KSCC1301). treatment 2 unknown_status NCT05496270
Surgery Alone Versus Neoadjuvant Treatment Followed by Surgery For MRI-defined T3 Mid-low Rectal Cancer No drug interventions Not Available Not Available completed NCT01643070
Preoperative CRT With or Without Induction Chemotherapy for Rectal Cancer With Liver Metastases treatment 2 unknown_status NCT00911170
PAVES: Pegfilgrastim Anti-vascular Endothelial Growth Factor (VEGF) Evaluation Study supportive_care 3 completed NCT03666442
Early Evaluation of Chemosensitivity for Low/Intermediated-risk Mid-low Stage II/III Rectal Cancer No drug interventions treatment 2 completed NCT05513742
A Study of CTX-009 in Adult Patients With Metastatic Colorectal Cancer No drug interventions treatment 2 active_not_recruiting NCT05629442
ctDNA and Organ Preservation/Pathologic CR in Rectal Cancer No drug interventions Not Available Not Available not_yet_recruiting NCT00543842
Bevacizumab, Erlotinib, and Capecitabine for Locally Advanced Rectal Cancer treatment 1 completed NCT03561142
Organ Preservation in Locally Advanced Rectal Cancer by Radiochemotherapy Followed by Consolidation Chemotherapy. No drug interventions treatment 2 unknown_status NCT04889742
Hyperthermia Enhanced Re-irradiation of Loco-regional Recurrent Tumors No drug interventions treatment 2 not_yet_recruiting NCT01431599
Short-course Preoperative Chemoradiotherapy for Rectal Cancer No drug interventions treatment 2 unknown_status NCT01064999
A Trial of High Intensity Versus Low Intensity Neoadjuvant Chemoradiotherapy in Locally Advanced Rectal Cancer treatment 2 / 3 unknown_status NCT06043999
Salvage Chemotherapy Versus Total Mesorectal Resection for Local Resection Rectal Cancer Patients No drug interventions treatment Not Available recruiting NCT01075399
Study of [F 18]HX4 Positron Emission Tomography (PET) as a Tool to Detect Hypoxia in Tumors No drug interventions Not Available 2 completed NCT06209099
Organ Preservation First Strategy and Intentional Watch and Wait for MRI Defined Low-risk Rectal Cancer No drug interventions treatment Not Available recruiting NCT03416699
Chinese TaTME Registry Collaborative No drug interventions Not Available Not Available unknown_status NCT01157806
Palliative Radiochemotherapy Against Palliative Surgery in Stage IV Rectal Cancer With Unresectable Metastases No drug interventions treatment 2 unknown_status NCT05609149
MRI Features in Neoadjuvant Treatment Decisions for Patients With Rectal Cancer No drug interventions Not Available Not Available completed NCT00601549
A Randomized Controlled Clinical Trial Comparing Oncological Results and Functional Recovery Between Laparoscopic and Open Method for the Treatment of Advanced Rectal Cancer After Concurrent Chemoradiation Therapy (CCRT) No drug interventions treatment 3 unknown_status NCT04084249
ctDNA-guided Surveillance for Stage III CRC, a Randomized Intervention Trial No drug interventions diagnostic Not Available active_not_recruiting NCT02266849
Loperamide vs. Placebo's Effect on Ileostomy Output: A Clinical Randomized Blinded Cross-over Study treatment 3 terminated NCT04678349
The Role of Partial Hydrolyzed Guar Gum in High Stoma Output Management Among Cancer Patients With Ileostomy No drug interventions supportive_care Not Available completed NCT04488549
Delayed Colorectal Cancer Care During Coronavirus Disease (COVID-19) Pandemic (DECOR-19) No drug interventions Not Available Not Available completed NCT02340949
Induction FOLFOX With or Without Aflibercept Followed by Chemoradiation in High Risk Locally Advanced Rectal Cancer treatment 2 completed NCT02864849
Total Neoadjuvant Induction and Consolidation CapeOX Plus IMRT With Capecitabine for MRI Defined High-risk Rectal Cancer treatment 2 completed NCT03975049
Triplet Combination or Doublet Regimen Versus Chemoradiation as Neoadjuvant Therapy for Locally Advanced Rectal Cancer No drug interventions treatment 3 not_yet_recruiting NCT04761536
Volume-outcome Relationship in Rectal Cancer Surgery No drug interventions Not Available Not Available completed NCT04167436
Fit for Surgery. Multimodal Prehabilitation in Colorectal Cancer Patients No drug interventions treatment 2 / 3 unknown_status NCT00307736
Bevacizumab, Erlotinib and 5-Fluorouracil With External Beam Radiation Therapy in Locally Advanced Rectal Cancer treatment 1 / 2 completed NCT06244836
Comparison of Two Bundles of Care to Reduce Surgical Site Infection in Colorectal Surgery (CCR-VINCat 2) No drug interventions prevention Not Available completed NCT05752136
Preoperative Short-course Radiation Followed by Envafolimab Plus CAPEOX for MSS Locally Advanced Rectal Adenocarcinoma treatment 3 recruiting NCT00972036
Selective Internal Radiation Therapy (SIRT) in Patients With Unresectable Colorectal Cancer Liver Metastases Who Failed Prior Intraarterial Pump Chemotherapy No drug interventions treatment 1 completed NCT01113736
Pilot Study Evaluating the Efficacy of AlloMEM After Loop Ileostomy No drug interventions prevention 1 completed NCT04638036
Fluorescence Molecular Endoscopy and Molecular Fluorescence-guided Surgery in Locally Advanced Rectal Cancer diagnostic 1 completed NCT03209336
Study of Intraoperative Radiotherapy for Middle and Low Rectal Cancer No drug interventions treatment Not Available unknown_status NCT05263336
Intraoperative Angiography Using ICG in Rectal Cancer Patients to Prevent Anastamotic Leak After Laparoscopic Anterior Resection of the Rectum No drug interventions treatment Not Available recruiting NCT04316013
Volatile Anaesthesia and Perioperative Outcomes Related to Cancer: The VAPOR-C Trial other 3 recruiting NCT02399813
A Phase 2 Study of Axalimogene Filolisbac (ADXS11-001) in Participants With Carcinoma of the Anorectal Canal treatment 2 completed NCT00640913
Early Reversal of Defunctioning Stoma Trial No drug interventions Not Available Not Available unknown_status NCT02887313
FOLFOX6 Totally Neoadjuvant Chemoradiation Therapy in Locally Advanced Rectal Cancer: A Real World Study treatment 2 unknown_status NCT00807313
Non-interventional Observational Study of Helical Tomotherapy for Oligometastatic Colorectal Cancer No drug interventions Not Available Not Available completed NCT01605318
Study of Labetuzumab Govitecan in Participants With Metastatic Colorectal Cancer treatment 1 / 2 terminated NCT03828318
Impact of a Patient-Centered Program for Low Anterior Resection Syndrome A Multicenter Randomized Controlled Trial No drug interventions supportive_care Not Available unknown_status NCT04293419
Durvalumab (MEDI4736) Plus Total Neoadjuvant Therapy (TNT) in Locally Advanced Rectal Cancer treatment 2 recruiting NCT03436719
Antibiotic Prophylaxis in Rectal Cancer Surgery: Oral With Intravenous Versus Intravenous Antibiotics. prevention Not Available unknown_status NCT04966819
Rectal Cancer Shared Care No drug interventions supportive_care Not Available unknown_status NCT00663819
Bioabsorbable Staple Line Reinforcement in Colorectal,Coloanal and Ileoanal Anastomoses No drug interventions treatment Not Available terminated NCT00297141
Preoperative Combined Radiochemotherapy for Patients With Rectal Carcinoma treatment 2 completed NCT00226941
A Phase 1-2 Trial of Cetuximab in Combination With Oxaliplatin, Capecitabine, and Radiation Therapy Followed by Surgery for Locally-advanced Rectal Cancer treatment 1 / 2 terminated NCT05516641
Prebiotics in Rectal Cancer No drug interventions other Not Available unknown_status NCT03390517
A Study of Perfusion of Colorectal Anastomosis Using FLuorescence AnGiography (FLAG-trial) No drug interventions treatment Not Available completed NCT05868317
Induction Chemotherapy Followed by Short Course Radiotherapy in Rectal Cancer treatment 2 active_not_recruiting NCT01586117
A Phase II Study of Amifostine for the Prevention of Acute Radiation-Induced Rectal Toxicity prevention 2 unknown_status NCT05049317
Multicenter Study on Postoperative Urinary and Sexual Function During Laparoscopic Functional Total Mesorectum Excision No drug interventions treatment Not Available recruiting NCT04127734
Treatment of Anastomotic Leakage After Rectal Cancer Resection No drug interventions Not Available Not Available unknown_status NCT06318234
PET/MR Evaluation of Regression Grading After Neoadjuvant Therapy for Rectal Cancer No drug interventions Not Available Not Available recruiting NCT05872334
The Safety and Feasibility of MONOFIX on Fascial Closure of Mid-line Wound After Minimally Invasive Colorectal Cancer Surgery No drug interventions prevention Not Available completed NCT02860234
Tailored Operative or Non-operative Management for Low-risk Rectal Cancer After Intensive Neoadjuvant Treatment Not Available Not Available completed NCT03466424
Short-course Radiotherapy (5×6Gy/7Gy/8Gy) Followed by Neo-adjuvant Chemotherapy for Locally Advanced Rectal Cancer No drug interventions Not Available Not Available recruiting NCT00867724
Clinical Study-evaluate Performance&Safety "Aer-O-Scope" in Colon of Low Risk Patients No drug interventions diagnostic Not Available completed NCT05672524
A Study of Tucatinib and Trastuzumab in People With Rectal Cancer treatment 2 recruiting NCT03359616
Transanal Versus Laparoscopic Total Mesorectal Excision For Rectal Cancer No drug interventions treatment Not Available unknown_status NCT06217016
Effect of ICCAUT Strategy on Postoperative Urinary Retention After Radical Rectal Cancer Surgery (ICCAUT-2) No drug interventions treatment Not Available suspended NCT03524716
Self-monitoring and Reminder Texts to Increase Physical Activity After Cancer II No drug interventions supportive_care Not Available completed NCT01182116
Quality of Life in Patients That Undergo J Pouch or Side to End Coloanal Anastomosis for Rectal Cancer No drug interventions treatment Not Available completed NCT03463616
MRI Imaging or CT Abdomen as Standard Work-up Before Treatment Planning for Rectal Cancer? No drug interventions Not Available Not Available completed NCT02077296
The Predictive Value of Cytokines on Response to Preoperative Chemoradiotherapy in Patients With Rectal Cancer No drug interventions Not Available Not Available completed NCT06053996
Hepatopulmonary Radio-sterilization With Immunotherapy No drug interventions treatment Not Available not_yet_recruiting NCT04674696
Short-course Radiotherapy With Induction and Consolidation Chemotherapy in Patients With Locally Advanced Rectal Cancer No drug interventions treatment 2 unknown_status NCT02546596
The Effect of Electro-Hyperthermia in Preoperative Radiotherapy for Locally Advanced Rectal Cancer No drug interventions treatment Not Available unknown_status NCT05515796
Multi-omics Sequencing in Neoadjuvant Immunotherapy of Gastrointestinal Tumors treatment 2 recruiting NCT06113796
Economic Analysis of Robotic Rectal Resection in German Health Care System No drug interventions Not Available Not Available completed NCT01995396
Hartmanns Procedure or Abdominoperineal Excision With Intersphincteric Dissection in Rectal Cancer: a Randomized Study No drug interventions treatment Not Available terminated NCT00611858
Cetuximab, 5-FU and Radiation as Neoadjuvant Therapy for Patients With Locally Advanced Rectal Cancer treatment 2 terminated NCT02435758
Multicenter Study on Preservation Versus Excision of Denonvilliers Fascia in L-PANP Surgery No drug interventions treatment Not Available completed NCT05575635
Neoadjuvant Treatment of Fruquintinib Combined With Concurrent Chemoradiotherapy for LARC treatment 2 not_yet_recruiting NCT03997435
FOLFOXIRI With or Without Intensification for Rectal Cancer No drug interventions treatment 2 recruiting NCT03459235
Assessment of Functional Digestive and Genitourinary Outcomes in Patients With Rectal Cancer. No drug interventions screening Not Available unknown_status NCT00250835
Combination of Oxaliplatin, Capecitabine, and Celecoxib With Concurrent Radiation for Rectal Cancer No drug interventions treatment 2 terminated NCT00648635
Relationship Between Quality of Life, Treatment Modalities, and Patient Treatment/Outcome Expectations No drug interventions Not Available Not Available active_not_recruiting NCT06505863
Quality of Life After Transanal Total Mesorectal Excision Compared to Traditional Total Mesorectal Excision No drug interventions Not Available Not Available not_yet_recruiting NCT05339763
Long Term Bowel Function Following Rectal Cancer Surgery No drug interventions prevention Not Available completed NCT02574663
TGR-1202 Alone and in Combination With Either Nab-paclitaxel + Gemcitabine or With FOLFOX in Patients With Select Relapsed or Refractory Solid Tumors treatment 1 completed NCT04917263
IMMUNOlogical Microenvironment in REctal Adenocarcinoma Treatment. No drug interventions Not Available Not Available recruiting NCT00630786
Conatumumab/Panitumumab Combination Metastatic Colorectal Cancer Study treatment 1 / 2 completed NCT00845039
A Study of Irinotecan and Cetuximab With or Without IMC-A12 for Treatment of Participants With Colon or Rectum Cancer Who Got Worse After Their First Treatment With Oxaliplatin and Bevacizumab treatment 2 terminated NCT01097239
Examining the Role of Transrectal High Intensity Focused Ultrasound (HIFU) in Rectal Pelvic Cancer No drug interventions supportive_care 1 / 2 withdrawn NCT04213222
Radiomics Assess of Bevacizumab Plus Chemo in Colorectal Cancer Liver Metastases Not Available Not Available unknown_status NCT05563922
Organ Preservation Strategy of Total Neoadjuvant Chemoradiotherapy for Low Rectal Carcinoma No drug interventions treatment 2 recruiting NCT05938322
Ketogenic Diet Compliance in Patients Affected by Locally Advanced Rectal Cancer Patients Who Undergo to Radiotherapy No drug interventions supportive_care Not Available not_yet_recruiting NCT04323722
Impact of Bladder Depletion on Mesorectal Movements During Radiotherapy in Rectal Cancer No drug interventions other Not Available recruiting NCT01835925
Rectal Cancer Consortium No drug interventions Not Available Not Available completed NCT04779125
APEMESH II - Perineal Reconstruction No drug interventions treatment Not Available completed NCT01461525
Comparison of Sphincter Preservation Surgery and Abdominoperineal Resection (APR): Prospective Clinical Trial No drug interventions treatment Not Available unknown_status NCT03413930
Transanal Versus Laparoscopic Total Mesorectal Excision for Rectal Cancer No drug interventions treatment Not Available withdrawn NCT00113230
Neoadjuvant Chemoradiation With RHUMAB VEGF (Avastin) for Rectal Cancer treatment 2 completed NCT05201430
Neoadjuvant FOLFOXIRI Versus CapeOX Chemotherapy for Local Advanced Rectal Cancer treatment 3 recruiting NCT05638048
Effect of Precise Grip Strength Training on PICC Catheter-Related Thrombosis in Cancer Patients No drug interventions prevention Not Available completed NCT02632448
A Study of LY2880070 in Participants With Advanced or Metastatic Cancer basic_science 1 / 2 recruiting NCT04855448
Evaluation of the Learning Curve in Low Anterior Resection for Rectal Resection With the Two Surgical Robots No drug interventions treatment Not Available completed NCT00636948
Rectal Cancer Trial On Defunctioning Stoma No drug interventions Not Available Not Available completed NCT04659148
Surgical and Oncological Outcomes in Patients With Ulcerative Colitis-associated Rectal Cancer No drug interventions Not Available Not Available unknown_status NCT04016948
Optical Biopsy for Distal Margin in Low Rectal Cancer No drug interventions diagnostic Not Available unknown_status NCT03222557
Electroacupuncture for Postoperative Ileus After Laparoscopic Surgery for Mid and Low Rectal Cancer No drug interventions treatment Not Available unknown_status NCT00353457
Capecitabine,Oxaliplatin & Erbitux Given Throughout Multi-Modal Therapy for Locally Advanced Rectal Adenocarcinoma treatment 2 terminated NCT00782457
Prospective Randomised Study Comparing Laparoscopic Versus Open Surgery in Patients With Rectal Cancer No drug interventions treatment 3 completed NCT04271657
RadioPathomics Artificial Intelligence Model to Predict nCRT Response in Locally Advanced Rectal Cancer No drug interventions Not Available Not Available completed NCT00969657
Validation of a Predictive Model After Complete Response in Rectal Cancer No drug interventions Not Available Not Available completed NCT01181557
A Questionnaire to Assess the Quality of Life of Rectal Cancer Patients With or Without Stoma No drug interventions Not Available Not Available completed NCT00622557
General Surgical Outcomes Quality Improvement Database (UH-SOCRATES) No drug interventions Not Available Not Available completed NCT02614157
Lateral Lymph Node Dissection After Neoadjuvant Chemo-radiation in Advanced Low Rectal Cancer No drug interventions treatment Not Available terminated NCT03597126
Short Term Outcomes of Robotic-assisted Intersphincteric Resection for Low Rectal Cancer No drug interventions treatment Not Available unknown_status NCT04673526
Laparoscopic Intersphincteric Resection in Elderly Patients No drug interventions treatment Not Available completed NCT05434026
Chinese Colorectal Cancer Database No drug interventions Not Available Not Available recruiting NCT02665026
Effectiveness and Safety Study on Different Timing of Preventive Ileostomy Closure After Surgery for Rectal Cancer No drug interventions treatment Not Available completed NCT05136326
Preoperative Chemoradiotherapy With CApecitabine and Temozolomide in MGMT Silenced, MSS, Locally Advanced RecTal Cancer treatment 2 recruiting NCT06056726
Evaluation of Surgical Complications and DFS in Obese Rectal Cancer Patients No drug interventions Not Available Not Available recruiting NCT04942626
Capecitabine-based Chemoradiotherapy in Combination With the IL-1 Receptor Antagonist Anakinra for Rectal Cancer Patients treatment 1 active_not_recruiting NCT04643366
Total Neoadjuvant Therapy With mFOLFOX and Short-course Radiation in Resectable Rectal Cancer No drug interventions treatment 2 recruiting NCT05914766
An Informational and Supportive Care Intervention for Patients With Locally Advanced Rectal Cancer No drug interventions supportive_care Not Available recruiting NCT01323166
Quality of Life After Abdominoperineal Resection for Rectal Cancer, Comparing Two Surgical Techniques No drug interventions Not Available Not Available completed NCT00635466
Phase II Trial to Evaluate Laparoscopic Surgery for Stage 0/I Rectal Carcinoma No drug interventions treatment 2 unknown_status NCT04083365
Capecitabine Plus Concomitant Radiation Therapy Followed by Durvalumab as Preoperative Treatment in Rectal Cancer treatment 2 recruiting NCT04496765
Early-onset Rectal Cancer No drug interventions Not Available Not Available completed NCT03144765
Multicenter Phase II Study of Transanal TME (taTME) No drug interventions treatment Not Available active_not_recruiting NCT05406765
Enhanced Recovery After Laparoscopic Colorectal Surgery treatment 4 completed NCT01745874
Diagnostic Value of Whole-Body MRI for Rectal Cancer Preoperative Staging No drug interventions Not Available Not Available unknown_status NCT03000374
Induction Therapy With Panitumumab + mFOLFOX-6 in Rectal Cancer and Quadruple Wild-type Mutation Before Surgery treatment 2 completed NCT02704520
Magnetic Resonance Tumour Regression Grade (mrTRG) as a Novel Biomarker - Phase III Non CTIMP Trial No drug interventions treatment Not Available recruiting NCT04923620
Neoadjuvant Cetuximab + Chemotherapy Combined With Short-course Radiotherapy Not Available Not Available recruiting NCT01033682
Evaluation of Bladder Volumes in Patients Receiving Radiotherapy to the Rectum, Using Kilovoltage Cone-beam Imaging No drug interventions Not Available Not Available unknown_status NCT04476082
Nutrition in Gastrointestinal Tumors No drug interventions Not Available Not Available completed NCT03598231
Effectiveness of Sacral Neuromodulation in Low Anterior Resection Syndrome No drug interventions treatment Not Available completed NCT04569331
Efficacy of Stimulation of the Efferent Loop and Rehabilitation of the Pelvic Floor in the Quality of Life of Patients Who Underwent Anterior Resection of the Rectum (ENESP): Randomized Clinical Trial No drug interventions supportive_care Not Available completed NCT00207831
Trial Testing Ftorafur (UFT) Associated With Neoadjuvant Radiotherapy Versus Radiotherapy Alone in Rectal Adenocarcinoma treatment 3 terminated NCT04486131
Lateral Nodal Recurrence in Rectal Cancer No drug interventions Not Available Not Available recruiting NCT00833131
The Randomised Study of Preoperative Radiotherapy With Consolidating Chemotherapy for Unresectable Rectal Cancer No drug interventions treatment 3 unknown_status NCT04215731
Neoadjuvant mFOLFOXIRI Plus Bevacizumab in Patients With High-Risk Locally Advanced Rectal Cancer treatment 3 recruiting NCT00949273
Safety and Efficacy Study of Cylindrical Abdominoperineal Resection to Treat Rectal Cancer No drug interventions Not Available Not Available unknown_status NCT00580073
Phase II Trial of Neoadjuvant FOLFOX4 and Cetuximab for Localized Adenocarcinoma of Rectum treatment 2 terminated NCT05556473
F-Tryptophan PET/CT in Human Cancers diagnostic 1 recruiting NCT01339273
Transversus Abdominis Plane (TAP) Block for Postoperative Analgesia After Laparoscopic Colonic Resection No drug interventions treatment Not Available completed NCT01972373
Visualization of Rectal Cancer During Endoscopy, Using a Fluorescent Tracer diagnostic 1 completed NCT01585727
Intraoperative Monitoring of the Pelvic Autonomic Nerves No drug interventions prevention Not Available completed NCT04601727
Oral & Faecal Microbiota Analysis in Patients With Rectal Cancer Requiring Pre-operative Therapy Before Surgery, & Correlation With Response No drug interventions Not Available Not Available completed NCT04850027
MRI-guided Lateral Lymph Node Dissection in Rectal Cancer No drug interventions Not Available Not Available recruiting NCT00081627
Clinical Trial in Patients With Metastatic Colorectal Cancer treatment 2 completed NCT05254327
Trial of the Efficacy and Safety of Short and Long Course Radiation Therapy With/Without BMX-001 treatment 2 recruiting NCT02728427
Multicenter Study on Suprapubic Catheterization Versus Transurethral Catheterization in Laparoscopic Surgery for Rectal Cancer No drug interventions prevention Not Available unknown_status NCT04200027
Robotic vs. TaTME Rectal Surgery (ROTA STUDY) No drug interventions Not Available Not Available not_yet_recruiting NCT05763927
Neoadjuvant Therapy for Locally Advanced Rectal Cancer With Fruquintinib, Toripalimab and SRT treatment 2 recruiting NCT02431676
Survivorship Promotion In Reducing IGF-1 Trial prevention 2 completed NCT04893876
The OPERa Study: Evaluating QoL After Rectal Cancer Surgery No drug interventions Not Available Not Available not_yet_recruiting NCT04622176
Magnetomotoric Ultrasound for Diagnostic Purposes in Rectal Cancer No drug interventions Not Available Not Available recruiting NCT06006260
Changes of Low Anterior Resection Syndrome and Balance Ability in Patients With Rectal Cancer. No drug interventions Not Available Not Available recruiting NCT06391060
Gender Differences in Robotic Surgery for Rectal Cancer: a Retrospective Study No drug interventions Not Available Not Available completed NCT05682794
Transanal Versus Laparoscopic Total Mesorectal Excision: a Cohort No drug interventions Not Available Not Available completed NCT06577194
A Single-Center, Single-Arm Study of Neoadjuvant Short-Course Radiotherapy Concurrent With IL-2 Followed by Sequential Immunotherapy With CAPOX Combined With PD-1 Antibody and IL-2 for Locally Advanced Rectal Cancer treatment 2 not_yet_recruiting NCT00963794
Diagnosis of Rectal Cancer by Electromagnetic Device No drug interventions diagnostic Not Available completed NCT04733794
Feasibility Bowel Dysfunction Program After Low Anterior Resection No drug interventions supportive_care Not Available completed NCT01648894
Influence of Lengthening the Interval Between Radiochemotherapy and Surgery on Complete Pathological Response in Rectal Cancer No drug interventions treatment 3 completed NCT03975491
The Exercise And Colorectal Cancer Treatment Trial No drug interventions treatment Not Available active_not_recruiting NCT01579591
VSL#3 Versus Placebo in Increasing the Pathological Major Response Rate in Patients With Rectal Cancer No drug interventions treatment 3 unknown_status NCT00297791
COLOR II: Laparoscopic Versus Open Rectal Cancer Removal No drug interventions treatment 3 completed NCT01863862
Organ Preservation in Elderly Patients With Rectal Cancer No drug interventions treatment Not Available unknown_status NCT06524362
Effect of Pelvic Rehabilitation After Low Anterior Resection for Cancer Rectum. - A Randomised Controlled Trial No drug interventions supportive_care Not Available not_yet_recruiting NCT05576480
SCRT Sequential Penpulimab in Combination With CAPEOX in the Neoadjuvant Treatment of MSS Locally Advanced Rectal Cancer treatment 2 not_yet_recruiting NCT05816980
Re-irradiation for Pelvic Recurrences in Rectal Cancer Patients No drug interventions treatment 2 completed NCT03931980
Robotic Versus Laparoscopic Approach for Rectal Cancer Surgery No drug interventions treatment Not Available completed NCT06271629
Impact of Quality of Life in the Patients With Sleep Disturbance From Low Anterior Resection Syndrome in Advanced Rectal Cancer Patients No drug interventions Not Available Not Available completed NCT01661829
An RCT for the Effect of Biofeedback Therapy the Prevention of AR Syndrome in Rectal Cancer Patients No drug interventions Not Available Not Available completed NCT03292289
Assessment of Symptoms and Consequences of Coloanal Continuity Reconstruction No drug interventions health_services_research Not Available active_not_recruiting NCT04592289
Short-term Outcomes of Full Bowel Preparation (MBP+OA) for Rectal Resections for Cancer Versus MBP Alone No drug interventions treatment Not Available recruiting NCT00337389
Phase III Randomized Study of 5-FU, CoFactor, and Avastin vs. 5-FU, LV and Avastin for First-Line Colorectal Cancer. treatment 3 unknown_status NCT00865189
A Study of Bevacizumab (Avastin) in Participants With Newly Diagnosed Locally Advanced Rectal Cancer treatment 2 completed NCT02702089
Hartmann's Versus Intersphincetric APE: A Prospective, Multicentre Study No drug interventions Not Available Not Available unknown_status NCT04525989
Preoperative Short-Course Radiation Therapy With PROtons Compared to Photons In High-Risk RECTal Cancer (PRORECT) No drug interventions treatment Not Available recruiting NCT01216189
Sexual Function and Wellbeing in Females With Rectal Cancer No drug interventions Not Available Not Available completed NCT05911789
Online Adaptive Radiation Therapy for Rectal Cancer No drug interventions treatment 1 / 2 not_yet_recruiting NCT04372992
The Stoma Closure Before or After Adjuvant Therapy Trial No drug interventions health_services_research Not Available terminated NCT05610592
Tumor Budding in Patients With Colorectal Cancer Under Different MMR Status No drug interventions Not Available Not Available completed NCT01271192
Efficacy and Safety Study of Neoadjuvant in Treating Patients With Resectable Local Recurrent Rectal Cancer No drug interventions treatment Not Available unknown_status NCT05424692
Drug Sensitivity Detection of Micro Tumor (PTC) to Guide Postoperative Adjuvant Treatment Strategy of Colorectal Cancer treatment Not Available recruiting NCT03548844
Local Excision Versus Total Mesorectal Excision In Pathological Complete Response (ypT0-1cN0) Mid- Or Low-Rectal Cancer After Neoadjuvant Therapy No drug interventions treatment Not Available unknown_status NCT02178644
Pilot Trial of KD018 With Neo-Adjuvant Concurrent Chemo-Radiation Therapy in Patients With Locally Advanced Rectal Cancer treatment 1 completed NCT02933944
Exploratory Study of TG02-treatment as Monotherapy or in Combination With Pembrolizumab to Assess Safety and Immune Activation in Patients With Locally Advanced Primary and Recurrent Oncogenic RAS Exon 2 Mutant Colorectal Cancer treatment 1 terminated NCT06246344
MRI Guided SIB Radiotherapy in Neoadjuvant Therapy for Advanced Rectal Cancer No drug interventions Not Available Not Available recruiting NCT06014944
Short-course Radiotherapy Combined With Furoquintinib and PD-1 Monoclonal Antibody No drug interventions treatment 2 not_yet_recruiting NCT02112240
Feasibility Study to Develop Sentinel Lymph Node Mapping in Rectal Cancer Patients diagnostic Not Available withdrawn NCT01421940
The Efficacy of Penile Rehabilitation Using Udenafil After Total Mesorectal Excision of Rectal Cancer supportive_care 4 completed NCT04738240
Endoscopic Visualisation of Anastomosis in Colorectal Cancer Surgery No drug interventions prevention Not Available completed NCT03283540
Transanal Total Mesorectal Excision for Rectal Cancer on Anal Physiology + Fecal Incontinence No drug interventions Not Available Not Available recruiting NCT00973440
Computer-Based Comprehensive Geriatric Assessment in Oncology for Individuals 70 or Older With Gastrointestinal Malignancies No drug interventions Not Available Not Available completed NCT00575640
Hydralazine as a Demethylating Agent in Rectal Cancer health_services_research 1 / 2 withdrawn NCT01133340
A Feasibility Study to Compare the Benefits of Endoscopic Tumor Clip Placement and 3T-MRI Simulation for Accurate Target Volume Definition for Rectal Cancer Patients Undergoing Pre-operative Chemoradiation No drug interventions treatment Not Available completed NCT03911167
An Analysis of Clinical Efficacy Based on the Robotic, Laparoscopic, and Open Approach in Radical Resection of Rectal Cancer No drug interventions Not Available Not Available completed NCT04103567
Determination of Microbiological Factors Associated With Poor Response to Neoadjuvant Treatment in Rectal Cancers No drug interventions other Not Available recruiting NCT05858567
Total Neoadjuvant Therapy With Short-course Radiation Followed by Envafolimab Plus CAPEOX for MSS Locally Advanced Ultra Low Rectal Adenocarcinoma treatment 2 recruiting NCT02243267
GI SPORE Colon Biosample Protocol No drug interventions Not Available Not Available completed NCT00020267
Vaccine Therapy in Treating Patients With Metastatic Cancer treatment 1 completed NCT01060501
Modulation of Adjuvant 5-FU by Folinic Acid and Interferon-alpha in Colon Cancer treatment 3 completed NCT04124601
Neoadjuvant Chemoradiotherapy With Sequential Ipilimumab and Nivolumab in Rectal Cancer treatment 2 completed NCT02651701
Rectal Cancer Staging Using Whole Body MR-PET No drug interventions Not Available Not Available completed NCT05471401
GI Organ Tracking Via Balloon Applicators No drug interventions device_feasibility Not Available withdrawn NCT00795301
A Study of Radiotherapy in Rectal Cancer Using Oxaliplatin, Capecitabine With or Without Cetuximab treatment 2 unknown_status NCT03550001
Carbon Nanoparticles as Lymph Node Tracer in Rectal Cancer After Neoadjuvant Radiochemotherapy No drug interventions other Not Available unknown_status NCT01111604
A Study of Ramucirumab or Icrucumab in Colorectal Cancer treatment 2 completed NCT02592304
Preoperative Assessment of Mesorectal Lymph Nodes by Dual Energy CT. PUMK-DECT No drug interventions diagnostic Not Available unknown_status NCT03120104
Physical Exercise for Colorectal Cancer Patients After Transanal Total Mesorectal Excision No drug interventions treatment Not Available unknown_status NCT02017704
Chemoradiation or Brachytherapy for Rectal Cancer treatment 2 completed NCT00335504
Atorvastatin Calcium, Oligofructose-Enriched Inulin, or Sulindac in Preventing Cancer in Patients at Increased Risk of Developing Colorectal Neoplasia prevention 2 completed NCT03413904
Transanal Versus Laparoscopic Total Mesorectal Excision for Rectal Cancer. No drug interventions treatment Not Available unknown_status NCT04664504
A Prospective Phase II Study of Individualized Neoadjuvant Chemoradiotherapy for Rectal Cancer Based on Recurrence Risk No drug interventions treatment 2 recruiting NCT05673772
Preoperative Sequential Short-course Radiation Therapy and FOLFOX for Locally Advanced Rectal Cancer No drug interventions treatment 2 recruiting NCT05879172
Electric Tubular Anastomosis in Rectal Cancer No drug interventions treatment Not Available completed NCT03619668
Chemo-radiotherapy as Main Treatment Strategy for Rectal Cancer. Can we Provide a More Precise and Effective Treatment No drug interventions Not Available Not Available active_not_recruiting NCT01914068
The Effects of a 9 Week Exercise Programme on Fitness and Quality of Life in Rectal Cancer Patients After Chemoradiotherapy and Before Surgery No drug interventions health_services_research Not Available completed NCT02905968
Transanual Tube Placement in Low Anterior Resection (LAR) for Rectal Cancer No drug interventions treatment 2 / 3 unknown_status NCT03015168
Prognostic Value of Neutrophil-to-lymphocyte Ratio (NLR) on Rectal Cancer Patients No drug interventions Not Available Not Available completed NCT01554969
Phase I Trial of Ganetespib, Capecitabine, and Radiation in Rectal Cancer treatment 1 completed NCT01814969
Preoperative Hyperfractionated Radiotherapy or Radiochemotherapy in Locally Advanced Rectal Cancer. No drug interventions treatment 3 unknown_status NCT06340646
Washington University Participant Engagement and Cancer Genomic Sequencing Center (WU-PE-CGS) No drug interventions health_services_research Not Available recruiting NCT04544046
Supportive Oncology Care At Home RCT No drug interventions supportive_care Not Available active_not_recruiting NCT06146946
Safety of Mid and Low Rectal Cancer Surgery Without Dissection of the No.253 Lymph Node (S-M-O-O-T-H) No drug interventions treatment Not Available not_yet_recruiting NCT06536712
Effects of Exosome Adminstration in Preventing Early Leakage in Rectal Cancer Patients Undergoing Low Anterior Resection No drug interventions prevention 1 not_yet_recruiting NCT02036112
Conventional Versus Individual Extralvator Abdominoperineal Excision for Advanced Lower Rectal Cancer No drug interventions treatment Not Available unknown_status NCT00677612
Histocompatibility Leukocyte Antigen (HLA)-A*0201 Restricted Peptide Vaccine Therapy in Patients With Colorectal Cancer No drug interventions treatment 1 / 2 terminated NCT03875612
Radiographic Validation of the Inferior Mesenteric Artery Tie Level in Rectal Cancer Surgery No drug interventions Not Available Not Available completed NCT00597610
Evaluating The Response to Pre-Operative Chemotherapy and/or Radiation Therapy For Rectal Cancer Using Three-Dimension Transrectal Ultrasound No drug interventions diagnostic Not Available completed NCT00996710
Genomic Structural Variation in Cancer Susceptibility No drug interventions Not Available Not Available active_not_recruiting NCT00468910
Aspirin in Preventing Colorectal Cancer in Patients at Increased Risk of Colorectal Cancer prevention 2 completed NCT02586610
Trial of Chemoradiation and Pembrolizumab in Patients With Rectal Cancer treatment 2 withdrawn NCT04108481
Immunotherapy With Y90-RadioEmbolization for Metastatic Colorectal Cancer treatment 1 / 2 suspended NCT03875781
Non Inferiority Study of Preoperative Chemotherapy Without Pelvic Irradiation for Rectal Cancer No drug interventions treatment 3 recruiting NCT04936581
Patient Reported Outcomes Following Cancer of the Rectum No drug interventions Not Available Not Available recruiting NCT04749381
The Role of TCM on ERAS of Rectal Cancer Patients No drug interventions prevention 2 unknown_status NCT00972881
Capecitabine, Irinotecan Hydrochloride, Cetuximab, and Radiation Therapy in Treating Patients Undergoing Surgery for Locally Advanced Rectal Cancer treatment 1 / 2 completed NCT01207895
Molecular Determinants Affecting Fluoro-L-thymidine (FLT) Positron Emission Tomography (PET) in Rectal Cancer No drug interventions basic_science 1 completed NCT05683795
PelvEx - Beating the Empty Pelvis Syndrome No drug interventions Not Available Not Available enrolling_by_invitation NCT06051695
A Study to Evaluate the Safety and Efficacy of A2B694, a Logic-gated CAR T, in Subjects With Solid Tumors That Express MSLN and Have Lost HLA-A*02 Expression No drug interventions treatment 1 / 2 recruiting NCT03479814
Adaptive Individualized High-Dose Radiotherapy Analysis-REctum-1 (AIDA-RE-1) No drug interventions treatment Not Available unknown_status NCT06380855
Flexible Colonoscope Assisted Hybrid Transanal Total Mesorectal Resection (taTME) No drug interventions Not Available Not Available recruiting NCT06256055
Phase 1 Study of UCMYM802 Injection in Mesothelin-positive Advanced Malignant Solid Tumors No drug interventions treatment 1 recruiting NCT06222255
The Safety and Efficacy of Transanal Irrigation in Patients With Sleep Disturbance From Low Anterior Resection Syndrome After Rectal Cancer Surgery (TraLARS) No drug interventions treatment Not Available recruiting NCT01126450
Lenalidomide and Cetuximab in Treating Patients With Metastatic Colorectal Cancer treatment 1 terminated NCT06162650
Total Neoadjuvant Therapy in Rectal Cancer No drug interventions treatment 2 recruiting NCT04004650
Gluteal Turnover Flap for Closure of the Perineal Wound After Abdominoperineal Resection for Rectal Cancer No drug interventions treatment Not Available unknown_status NCT01582750
Endoscopic Ultrasound Predict the Sensitivity of Stage II / III Rectal Cancer Preoperative Concurrent Chemoradiotherapy No drug interventions Not Available Not Available unknown_status NCT03516708
Epacadostat (INCB024360) Added to Preoperative Chemoradiation in Patients With Locally Advanced Rectal Cancer treatment 1 / 2 recruiting NCT03577808
Organoids in Predicting Chemoradiation Sensitivity on Rectal Cancer No drug interventions Not Available Not Available unknown_status NCT00578838
Magnetic Resonance Study of Liver in Chemotherapy No drug interventions Not Available Not Available completed NCT04573738
Safety and Feasibility Study of Robotic Assisted Transanal Total Mesorectal Excision for Rectal Cancer No drug interventions treatment Not Available completed NCT00418938
SPIRITT - Second-Line Panitumumab Irinotecan Treatment Trial treatment 2 completed NCT01111838
Clinical and Translational Study of STA-9090 treatment 2 completed NCT05336643
Radioisotope and Fluorescence Guidance in Rectal Cancer No drug interventions device_feasibility Not Available not_yet_recruiting NCT01363843
Complete Neoadjuvant Treatment for REctal Cancer (CONTRE) treatment 2 completed NCT03420443
Action of Synbiotics on Irradiated GI Mucosa in Rectal Cancer Treatment No drug interventions prevention Not Available completed NCT00910143
Introduction and Influence of Total Mesorectal Excision (TME) in the Treatment of Rectal Cancer No drug interventions Not Available Not Available completed NCT02910843
Neoadjuvant Treatment With Regorafenib and Capecitabine Combined With Radiotherapy in Locally Advanced Rectal Cancer treatment 1 terminated NCT02311803
Preservation Versus Excision of Denonvilliers Fascia in L-PANP Surgery No drug interventions treatment Not Available unknown_status NCT05815303
XELOX Combined With Cadonilimab Versus XELOX as Neoadjuvant Treatment for Locally Advanced, pMMR Rectal Cancer treatment 2 recruiting NCT04672603
Complete Versus Partial Preservation of Denonvilliers' Fascia on Urogenital Function in Locally Advanced Rectal Cancer No drug interventions treatment Not Available recruiting NCT05316103
Targeted Optical Biopsy for Local Rectal Scars in Rectal Cancer Patients After Neoadjuvant Chemoradiotherapy No drug interventions diagnostic Not Available recruiting NCT04857203
The Role of Vitamin D in Predicting Response to Neoadjuvant Therapy in Patients With Rectal Cancer No drug interventions Not Available Not Available unknown_status NCT04697303
Cross-sectional Study of Anorectal Function and Quality of Life in Patients With Middle and Low Rectal Cancer No drug interventions Not Available Not Available completed NCT00738790
Preoperative Radiotherapy and Local Excision in Rectal Cancer No drug interventions treatment 3 unknown_status NCT03854890
Fluorescent Lymphography-Guided Lymphadenectomy In Laparoscopic Proctectomy treatment Not Available unknown_status NCT06274190
Personalized Care Pathways for Bowel Symptoms in Rectal Cancer patients_development of E-diary No drug interventions supportive_care Not Available recruiting NCT01308190
Preoperative Chemoradiotherapy and Transanal Endoscopic Microsurgery Versus Total Mesorectal Excision in T2-T3s N0, M0 Rectal Cancer treatment 3 completed NCT03871790
Peptide-based Immunization for Colon- and and Pancreas-carcinoma No drug interventions Not Available Not Available completed NCT03623464
RCT of Mobile Apps & FitBit v. Usual Care No drug interventions other Not Available active_not_recruiting NCT05284864
Timing Evaluation of Stoma Closure (TIMES). Early vs Late Closure of Stoma After Rectal Cancer Surgery. No drug interventions treatment Not Available recruiting NCT05176964
Chemotherapy and Tislelizumab With Split-course HFRT for Locally Advanced Rectal Cancer Not Available Not Available recruiting NCT00422864
A Single Arm Trial of Oxaliplatin and 5FU With Concurrent Radiation in Patients With Metastatic Rectal Cancer treatment 2 completed NCT02965521
Survivor Choices for Eating and Drinking - Colorectal Cancer No drug interventions other Not Available completed NCT02052921
Observation Versus Surgical Resection in Patients With Rectal Cancer Who Achieved Complete Clinical Response After Neoadjuvant Chemoradiotherapy No drug interventions treatment Not Available terminated NCT05873621
Indocyanine Green-guided Lymphadenectomy in Laparoscopic Total Mesorectal Excision for Low Rectal Cancer After Neoadjuvant Chemoradiotherapy No drug interventions treatment Not Available recruiting NCT01951521
RECTAL BOOST Study No drug interventions treatment Not Available unknown_status NCT01579721
Prospective Randomized Study of SILS Versus CLS for Rectal Cancer No drug interventions treatment 4 completed NCT04334421
APEMESH- Preventing Perineal Complications After Abdominoperineal Resection No drug interventions Not Available Not Available completed NCT01558921
Rectal Cancer And Pre-operative Induction Therapy Followed by Dedicated Operation. The RAPIDO Trial No drug interventions treatment 3 active_not_recruiting NCT04223102
Microbiome and Rectal Cancer No drug interventions basic_science Not Available active_not_recruiting NCT01216202
Sexual Function and Wellbeing in Males With Rectal Cancer No drug interventions Not Available Not Available completed NCT03253302
Laparoscopic Assisted Transanal Total Mesorectal Excision for Rectal Cancer in Low Site No drug interventions Not Available Not Available unknown_status NCT04743102
Multi-points and Full-thickness Biopsy in the Diagnosis of cCR After Neoadjuvant Therapy for Rectal Cancer No drug interventions treatment Not Available recruiting NCT05696002
Advanced Pelvic Surgical Oncology Database - Prospective Observational Study No drug interventions Not Available Not Available recruiting NCT03634202
Study of Radiation Therapy in Combination With Xeloda, for Initially Metastatic, Low and Middle Rectal Cancer treatment Not Available terminated NCT02603302
Radiation Dose Escalation in Locally Advanced Rectal Cancer No drug interventions treatment 2 unknown_status NCT03487484
Quality of Life in Patients With Rectal Cancer Receiving Total Mesorectal Excision With or Without Stoma No drug interventions Not Available Not Available terminated NCT01995084
In Vivo Assessment of Hypoxia in Gastro-intestinal Cancer Using 18F-HX4-PET: an Optimization and Reproducibility Study No drug interventions diagnostic Not Available completed NCT02236884
The Feasibility and Safety of No-scar Transanal Total Mesorectal Excision for Rectal Cancer No drug interventions treatment 1 / 2 completed NCT02177084
Percutaneous Tibial Nerve Stimulation in the Treatment of Anterior Resection Syndrome After Rectal Cancer Surgery No drug interventions treatment 2 unknown_status NCT03908684
Ultrasound Spectroscopy as Early Indicators of Radiation Treatment Response in Prostate, Rectum and Head & Neck Cancers No drug interventions Not Available Not Available recruiting NCT01296984
Oncological and Functional Result of AbdominoPerineal Extra Levator Resection for Distal Rectal Cancer No drug interventions Not Available Not Available completed NCT01043484
Safety and Efficacy Study to Compare Capecitabine + Bevacizumab Versus Capecitabine, Concomitantly With Radiotherapy as Neoadjuvant Treatment for Patients With Localized and Resectable Rectal Cancer treatment 2 completed NCT03921684
Trial of Nivolumab With FOLFOX After Chemoradiation in Rectal Cancer Patients treatment 2 recruiting NCT06104579
Concordance Between Monitoring Systems for Organ/Space Surgical Site Infections in Rectal Surgery No drug interventions Not Available Not Available completed NCT05526079
Watchful Waiting for Complete Responders to Therapy in Rectal Cancer No drug interventions treatment 2 recruiting NCT04028479
The Registry of Oncology Outcomes Associated With Testing and Treatment No drug interventions Not Available Not Available recruiting NCT05215379
Neoadjuvant Chemoradiation Therapy Combined With Immunotherapy for MSS Ultra-low Rectal Cancer No drug interventions treatment 2 / 3 recruiting NCT01941979
A Study Comparing Adjuvant Chemotherapy Versus Observation for Patients With Rectal Adenocarcinoma After Neoadjuvant Chemo-Radiotherapy Treatment. treatment 3 unknown_status NCT00677287
Histocompatibility Leukocyte Antigen (HLA)-A*2402 Restricted Peptide Vaccine Therapy in Patients With Colorectal Cancer No drug interventions treatment 1 / 2 terminated NCT01923987
Short Course Radiotherapy Followed Intensive Chemotherapy With Delayed Surgery for Rectal Cancer With Synchronous Distant Metastasis treatment 2 unknown_status NCT00267787
Molecular Genetic and Pathological Studies of Anal Tumors No drug interventions Not Available Not Available terminated NCT05939687
Prophylactic Mesh Placement During Stoma Closure After Low Anterior Resection No drug interventions prevention 3 recruiting NCT02163187
Sacral Neuromodulation (SNM) With InterStimTM for Bowel Dysfunction Following Surgery for Rectal Cancers With Sphincter Preservation No drug interventions treatment 2 / 3 terminated NCT03957733
Phase II/III Study to Assess the Efficacy of Neoadjuvant Consolidation Chemotherapy in Rectal Cancer Patients. No drug interventions treatment 2 / 3 recruiting NCT01130233
Randomized Trial on Robotic Assisted Resection for Rectal Cancer No drug interventions treatment 3 unknown_status NCT06542354
Prehabilitation During Neoadjuvant Chemoradiotherapy for Rectal Cancer No drug interventions supportive_care Not Available completed NCT02293954
Copper Cu 64 Anti-CEA Monoclonal Antibody M5A PET in Diagnosing Patients With CEA Positive Cancer diagnostic Not Available active_not_recruiting NCT06404554
A Prediction Model of Anastomotic Stricture After Rectal Cancer No drug interventions Not Available Not Available completed NCT00661154
Avastin/[18-F]-5-fluorouracil PET/CT Imaging Feasibility Project Not Available Not Available completed NCT00470951
Randomized Prospective Trial for Laparoscopic vs Open Resection for Rectal Cancer No drug interventions treatment 3 unknown_status NCT05572151
Determining the Optimal Examined Lymph Node for Accurate Staging and Long-term Survival in Rectal Cancer No drug interventions Not Available Not Available completed NCT02609451
Closure of Protective Ileostomy 2 vs. 12 Weeks After TME No drug interventions treatment Not Available terminated NCT03013153
Low or High Ligation of the IMA With Apical Lymph Node Dissection in Rectal Cancer Laparoscopic Surgery No drug interventions treatment Not Available unknown_status NCT02153853
Does Obesity Increase the Risk of Conversion and Short Term Complications in Laparoscopic Rectal Surgery? No drug interventions Not Available Not Available unknown_status NCT01376453
Pre-operative 5-Fluorouracil (5-FU) and Sorafenib With External Radiation in Locally Advanced Rectal Cancer treatment 1 completed NCT06397053
Comparison of Robotic Versus Laparoscopic Surgery for Visceral Obesity in Mid-Low Rectal Cancer: A Propensity-Matched Analysis No drug interventions Not Available Not Available completed NCT06501053
Contact Radiotherapy for Rectal Cancer No drug interventions treatment Not Available not_yet_recruiting NCT04852653
A Prospective Feasibility Study Evaluating Extracellular Vesicles Obtained by Liquid Biopsy for Neoadjuvant Treatment Response Assessment in Rectal Cancer No drug interventions Not Available Not Available recruiting NCT03402477
"Watch and Wait" After Neo-adjuvant Chemoradiotherapy for Primary Locally Advanced Rectal Cancer. No drug interventions Not Available Not Available terminated NCT01006577
Side-to-end Anastomosis Versus Colon J Pouch for Reconstruction After Low Anterior Resection for Rectal Cancer (SAVE) No drug interventions treatment Not Available unknown_status NCT01189877
Characterization of Rectal Cancer Hypoxia Using pO2 Histography and Immunohistochemistry for Hypoxia-Related Proteins No drug interventions diagnostic Not Available completed NCT02081547
IPC Status as a Surgical Quality Marker in Rectal Cancer Surgery No drug interventions Not Available Not Available unknown_status NCT05969847
Organ Preservation Following Enverolimab-based Total Neoadjuvant Therapy for Locally Advanced Very Low Rectal Cancer treatment 2 not_yet_recruiting NCT06050447
Factors Affecting the Results of Treatment of Patients With Colorectal Cancer No drug interventions Not Available Not Available recruiting NCT02112747
Adherence to Colon Cancer Screening (ACCS) No drug interventions health_services_research Not Available completed NCT01481545
Bevacizumab With Pelvic Radiotherapy And Primary Chemotherapy in Patients With Poor-Risk Rectal Cancer treatment 2 completed NCT05523245
Predicting the Efficacy of Neoadjuvant Therapy in Patients With Locally Advanced Rectal Cancer Using an AI Platform Based on Multi-parametric MRI No drug interventions Not Available Not Available recruiting NCT05274945
Total Neoadjuvant Therapy Versus Standard Neoadjuvant Chemoradiation for Locally Advanced Rectal Cancer No drug interventions treatment 2 completed NCT00235898
Clinical Trial in Patients With Metastatic Colorectal Cancer treatment 2 completed NCT04359498
Retrospective Study of Surgical Complications in Patients With Defunctioning Stoma After Low Anterior Resection (LAR) No drug interventions Not Available Not Available completed NCT01985698
A Trial of Robotic-assisted Versus Laparoscopic Abdominoperineal Resection for Treating Low Rectal Cancer No drug interventions treatment Not Available completed NCT01606098
The Role of Surgery of the Primary Tumour in Patients With Synchronous Unresectable Metastases of Colorectal Cancer treatment 3 completed NCT04075305
The MOMENTUM Study: The Multiple Outcome Evaluation of Radiation Therapy Using the MR-Linac Study No drug interventions Not Available Not Available recruiting NCT00028405
Photodynamic Therapy System for Patients With Refractory/Unresponsive Solid Tumors No drug interventions treatment 1 completed NCT04134897
Neoadjuvant Chemotherapy in Patients With Moderate Risk Mid Rectal Cancer treatment 3 enrolling_by_invitation NCT04927897
DETECT: Target Volume for Rectal Endoluminal Radiation Boosting No drug interventions Not Available Not Available recruiting NCT00606983
Prevention of Acute Voiding Difficulty After Radical Proctectomy treatment 3 completed NCT01671683
Additional Chemotherapy After Neoadjuvant Chemoradiotherapy in Patients With Locally Advanced Rectal Cancer No drug interventions Not Available Not Available completed NCT04245683
Feasibility of Non-Operative Management of Rectal Cancer in a Rural Population No drug interventions Not Available Not Available recruiting NCT02589483
Reinforcement of Rectal Anastomosis-RORA No drug interventions prevention Not Available unknown_status NCT03325361
The Role of Transanal Tube Drainage as A Mean of Prevention of Anastomotic Leakage Anastomotic Leakage No drug interventions prevention Not Available unknown_status NCT05939661
A Multicenter Single-arm P2 to Evaluate Safety and Efficacy of the Total Neoadjuvant Therapy for cT2 Rectal Cancer No drug interventions treatment 2 recruiting NCT04637061
Rectal Cancer Anastomosis 4 Check Study Not Available Not Available unknown_status NCT06212128
RAPIDO vs LCRT vs Upfront Surgery - a Prospective Cohort Study No drug interventions Not Available Not Available active_not_recruiting NCT03431428
Comparison of Short-term Efficacy and Long-term Prognosis for Reduction Surgery and Radical Resection in Almost-cCR Rectal Cancer Patients No drug interventions treatment 3 unknown_status NCT01650428
Bevacizumab And Combination Chemotherapy in Rectal Cancer Until Surgery treatment 2 completed NCT02626728
A Prospective Feasibility Study for TAMIS No drug interventions Not Available Not Available completed NCT00807911
Adjuvant Chemotherapy After Preoperative Chemoradiotherapy to Treat Rectal Cancer No drug interventions treatment 2 unknown_status NCT03765411
Safe Colorectal Surgery in the Elderly No drug interventions Not Available Not Available completed NCT04801511
Preoperative IMRT With Concurrent High-dose Vitamin C and mFOLFOX6 in Locally Advanced Rectal Cancer treatment 2 recruiting NCT04406311
Italian Validation of the LARS Score No drug interventions Not Available Not Available completed NCT00527111
Pre-op Rectal ChemoRad +/- Cetuximab treatment 2 completed NCT00789893
Study of Vaginal Dilator Use After Pelvic Radiotherapy No drug interventions Not Available Not Available completed NCT03700593
Feasibility and Safety of Single Port Robot in Colorectal Procedures No drug interventions Not Available Not Available unknown_status NCT02465593
A Study of PEP503(Radio-enhancer) With Radiotherapy and Chemotherapy for Patients With Rectal Cancer treatment 1 / 2 terminated NCT01500993
Capecitabine in the Perioperative Treatment of Rectal Cancer treatment 3 completed NCT00973193
Preoperative Panitumumab and Radiotherapy in Rectal Cancer treatment 2 terminated NCT06443671
Neoadjuvant Fruquintinib Plus Tislelizumab Combined With mCapeOX Versus CapeOX for Mid-high pMMR/MSS Locally Advanced Rectal Cancer treatment 2 / 3 not_yet_recruiting NCT03007771
Magnetic Resonance-guided High-Intensity Focused Ultrasound (MR-HIFU) Used for Mild Hyperthermia No drug interventions device_feasibility 1 withdrawn NCT04357171
PReventive cOlostomy vs Ileostomy in Low anTErior reCTal Resection No drug interventions treatment Not Available completed NCT04098471
Simple Transanal Local Excision，Transanal Local Excision Following Radiotherapy Versus Total Mesorectum Excision for the Treatment of the Ultra-low T2N0M0 Rectal Cancer No drug interventions treatment Not Available not_yet_recruiting NCT06210971
Neoadjuvant Chemoradiation With Nal-IRI and Capecitabine Guided by UGT1A1 Status in Patients With Rectal Cancer treatment 2 recruiting NCT02551471
Benchmarking Trial Between France and Australia Comparing Management of Primary Rectal Cancer Beyond TME (Total Mesorectum Excision) and Locally Recurrent Rectal Cancer No drug interventions Not Available Not Available completed NCT02514278
Optimisation of Response for Organ Preservation in Rectal Cancer : Neoadjuvant Chemotherapy and Radiochemotherapy vs. Radiochemotherapy supportive_care 3 completed NCT02579278
Circulating Tumour DNA (ctDNA) in Patients With Colorectal Cancer and the Relationship to Imaging Features of Extramural Venous Invasion No drug interventions Not Available Not Available recruiting NCT04316078
A Novel Patient Engagement Platform Among Patients With Gastrointestinal Malignancies No drug interventions health_services_research Not Available completed NCT03251378
A Multi-Center, Open-Label Study of Fruquintinib in Solid Tumors, Colorectal, and Breast Cancer treatment 1 active_not_recruiting NCT03781778
Pilot Trial of Resistant Starch in Stage I-III Colorectal Cancer Survivors No drug interventions prevention 2 terminated NCT00137878
TNFerade™ Plus Chemo/Radiation/Surgery for Rectal Cancer treatment 2 completed NCT01861678
Randomized Controlled Trial to Evaluate High Tie Versus Low Tie of the Inferior Mesenteric Artery in Anterior Resection No drug interventions treatment 3 unknown_status NCT04635488
Prediction Model for Lateral Lymph Node Metastasis No drug interventions Not Available Not Available unknown_status NCT04670588
Response Assessment by Circulating Tumor DNA in Patients With Locally Advanced Rectal Cancer No drug interventions Not Available Not Available withdrawn NCT06214988
Selective Defunctioning Stoma in Low Anterior Resection for Rectal Cancer No drug interventions treatment Not Available not_yet_recruiting NCT06263088
EQUITY GI: A Prospective Study to Enhance Quality, Inclusivity, and Trial Participation in Black Patients With Gastrointestinal Cancer. No drug interventions supportive_care Not Available not_yet_recruiting NCT03280407
NEOadjuvant Chemotherapy Only Compared With Standard Treatment for Locally Advanced Rectal Cancer treatment 2 recruiting NCT02488707
Minimally Invasive Sphincter Sparing Total Mesorectal Excision for Ultra-low Rectal Cancer After Initial Chemo-radiotherapy (MISS-TRICR). No drug interventions treatment 2 unknown_status NCT04735107
Mucosal Flap Reinforced Colorectal Anastomosis and Trans-Anal Vacuum Drainage: A Feasibility Study No drug interventions treatment Not Available unknown_status NCT05664607
Sarcopenia and Multimodal Rehabilitation on the Prognosis of Rectal Cancer Patients Receiving CCRT No drug interventions supportive_care Not Available not_yet_recruiting NCT01407107
Dose Escalation Trial of Nitroglycerin, 5-flourouracil and Rad Therapy for Rectal Cancer treatment 1 completed NCT04177407
Protocol: Reconstruct the Pelvic Peritoneum Using BPF No drug interventions treatment Not Available unknown_status NCT02591407
Trial Comparing Transversus Abdominis Plane Block Versus Epidural Anesthesia for Pain Management in Colorectal Surgery No drug interventions supportive_care Not Available unknown_status NCT05671809
Effects of Different Treatment for Anorectal Function of Patients With Rectal Cancer No drug interventions Not Available Not Available not_yet_recruiting NCT00399009
Comparative Study of Circular Stapling Instruments No drug interventions treatment Not Available terminated NCT01325909
Exercise Training in Colorectal Cancer Patients No drug interventions treatment Not Available completed NCT03923309
Oncologic Risk of Rectal Preservation Against Medical Advice After Chemoradiotherapy for Rectal Cancer No drug interventions Not Available Not Available completed NCT01458509
Feasibility and Psychometric Properties of Paper vs. Web vs. Automated Telephone Administration of Patient Reported Outcome Surveys No drug interventions Not Available Not Available completed NCT04795609
Effect of a Post-operative Protocol of Early Mobilization on Functional Recovery and Postoperative Complications After Immediate Internal Pudendal Artery Perforator Flap Reconstruction for Irradiated Abdominoperineal Resection Defects: a Prospective, Randomized and Controlled Clinical Study. No drug interventions treatment Not Available unknown_status NCT02445456
Feasibility of Sentinel Lymph Node Biopsy in Rectal Cancer No drug interventions diagnostic Not Available terminated NCT01525056
Rectal Cancer: Local Staging, Re-staging and Assessment of Lymph Nodes Using Pet-Ct, CT-Perfusion and 3T MRI No drug interventions diagnostic 2 completed NCT06123156
Interest of Early Erectile Rehabilitation With Sildenafil After Radiotherapy and Proctectomy for Rectal Cancer treatment 3 not_yet_recruiting NCT02008656
Trial Evaluating 3-year Disease Free Survival in Patients With Locally Advanced Rectal Cancer Treated With Chemoradiation Plus Induction or Consolidation Chemotherapy and Total Mesorectal Excision or Non-operative Management treatment 2 active_not_recruiting NCT01904656
CBPR Strategies to Increase Colorectal Cancer Screening in Ohio Appalachia No drug interventions health_services_research Not Available completed NCT02907385
Efficacy and Safety of LifeSeal™ Kit for Colorectal Staple Line Sealing No drug interventions treatment 3 unknown_status NCT05356585
Circulating Tumor DNA to Monitor the Efficacy of Total Neoadjuvant Therapy for Rectal Cancer No drug interventions Not Available Not Available withdrawn NCT05933785
the Value of Transanal Endoscopic ISR No drug interventions Not Available Not Available completed NCT02584985
Evaluate Efficacy, Morbidity and Functional Outcome of Endoscopic TranAnal Proctectomy vs Standard Transabdominal Laparoscopic Proctectomy for Rectal Cancer No drug interventions treatment 3 unknown_status NCT03498885
Comparison of Low and High Ligation With Apical Lymph Node Dissection in the Laparoscopy Rectal Cancer No drug interventions treatment Not Available recruiting NCT02682485
Serial Endoscopic Surveillance & Direct Topical Antibiotics to Define the Role of Microbes in Anastomotic Healing prevention 2 withdrawn NCT05129215
Development and Validation of The Post-RT LARS Prediction Model (PORTLARS) No drug interventions Not Available Not Available completed NCT05007015
Transanal Irrigation for the Management of LARS No drug interventions supportive_care Not Available recruiting NCT02629315
Carnoy's Solution Versus Formalin in Rectal and Gastric Cancer Specimens Following: a Randomized Trial No drug interventions diagnostic Not Available completed NCT06382415
Organ/Space Surgical Site Infection and Recurrence and Survival in Rectal Cancer Surgery No drug interventions Not Available Not Available completed NCT01287637
Early Closure of Temporary Ileostomy No drug interventions treatment Not Available completed NCT04380337
Organ Preservation Program Using Short-Course Radiation & FOLFOXIRI in Rectal Cancer No drug interventions treatment 2 active_not_recruiting NCT04512937
Computer Navigation-assisted Surgery for Locally Advanced and Recurrent Rectal Cancer No drug interventions treatment Not Available active_not_recruiting NCT03951337
64Cu-ATSM PET/CT in Rectum Cancer (TEP 64Cu-ATSM-Rectum) No drug interventions diagnostic 2 active_not_recruiting NCT00414232
Prospective Assessment of Symptoms and Quality of Life in Rectal Cancer Patients Receiving Chemo-Radiotherapy No drug interventions Not Available Not Available completed NCT01489332
Induction Chemotherapy,Radiochemotherapy, Consolidation Chemotherapy in Preoperative Treatment of Rectal Cancer No drug interventions treatment 2 unknown_status NCT00041652
Safety Study of hMN14 to Treat Either Colorectal or Breast Cancer treatment 1 / 2 completed NCT04287400
Prospective Trial for the Evaluation of Radiogenomics in Advanced Rectal Cancer No drug interventions Not Available Not Available recruiting NCT01003600
Colorectal Cancer Survivors' Needs and Preferences for Survivorship Information No drug interventions Not Available Not Available completed NCT05266300
Implementation and Quality Assurance of DPYD-genotyping in Patients Treated With Fluoropyrimidines. No drug interventions Not Available Not Available completed NCT05883800
Total Neoadjuvant Treatment Combined With Adaptive Radiotherapy for Rectal Cancer No drug interventions treatment Not Available recruiting NCT00200200
Hepatic Arterial Infusion With Floxuridine and Dexamethasone Combination With Chemotherapy With/Without Bevacizumab for Hepatic Metastases From Colorectal Cancer treatment 2 active_not_recruiting NCT03151759
MMP-7 Modulation by Short and Long Term Radiotherapy in Rectal Cancer Patients No drug interventions Not Available Not Available completed NCT04481659
Completely Abdominal Approach Laparoscopic Partial Intersphincteric Resection for Rectal Cancer No drug interventions treatment Not Available not_yet_recruiting NCT06396975
Comparison of Short-term Outcomes of Robotic and Laparoscopic Surgery in Patients With Different Body Mass Index for Mid and Low Rectal Cancer No drug interventions Not Available Not Available completed NCT05457075
Immune Checkpoints in Predicting Response to Neoadjuvant Therapy in Rectal Cancer No drug interventions Not Available Not Available completed NCT01345175
Rifaximin and Placebo in the Treatment of Bowel Dysfunction After Anterior Resection for Rectal Cancer treatment 3 completed NCT03281070
Anastomotic Leakage After Anterior Resection of Rectal Cancer No drug interventions Not Available Not Available unknown_status NCT04621370
A Trial of Durvalumab (MEDI 4736) in Combination With Extended Neoadjuvant Regimens in Rectal Cancer treatment 2 not_yet_recruiting NCT01797770
Trial on Mechanical Bowel Preparation in Laparoscopic Colorectal Surgery Not Available Not Available unknown_status NCT03899870
Factors Predicting Recurrence in Rectal Cancer After Surgery No drug interventions Not Available Not Available completed NCT00687570
Bowel Preparation Before Rectal Cancer Surgery No drug interventions Not Available Not Available completed NCT03607370
Timing for Rectal Surgery After Chemoradiotherapy No drug interventions treatment Not Available active_not_recruiting NCT06059170
Rectal Cancer Survivorship: Impact of Low Anterior Resection Syndrome (LARS) on the Quality of Life No drug interventions supportive_care Not Available completed NCT05907642
Effects of Dried Plum (Prune) Intake on the Incidence of Low Anterior Resection Syndrome in Patients With Rectal Cancer No drug interventions treatment Not Available completed NCT00346099
Study of Panitumumab Given First With Capecitabine and Oxaliplatin (CAPOX) and Then With Capecitabine and Radiation of the Pelvis for Treatment of Patients With Rectal Cancers That May or May Not Have Spread Beyond the Rectum treatment 2 withdrawn NCT05910099
Taking a Look at Patient Experiences In Rectal Cancer Clinical Trials No drug interventions Not Available Not Available not_yet_recruiting NCT04417699
SHOrt Course Radiation and TASOX (TAS102 Plus Oxaliplatin) Chemotherapy in Operable Rectal Cancer treatment 2 completed NCT02012699
Integrated Cancer Repository for Cancer Research No drug interventions Not Available Not Available recruiting NCT00040599
Safety Study of 90Y-hMN14 to Treat Colorectal Cancer treatment 1 / 2 completed NCT06519006
Effectiveness of Pelvic Floor Exercise to Prevent LARS (Low Anterior Resection Syndrome) No drug interventions prevention Not Available recruiting NCT05498506
Multiple Firings in Double-stapled Colorectal Anastomosis No drug interventions Not Available Not Available completed NCT06126406
Clinical Study of CEA Targeting Chimeric Antigen Receptor T Lymphocytes（CAR-T） for CEA Positive Advanced Malignant Solid Tumors No drug interventions treatment 1 recruiting NCT02129049
Telephone-Based Educational Intervention in Improving Communication Between Patients With Stage 0-III Cancer and Their Children No drug interventions supportive_care Not Available completed NCT04751149
Incidence of Acute Urine Retention: Randomized Clinical Trial Comparing Early, Mid or Late Urinary Catheter Removal in Patients With Rectal Resection No drug interventions prevention Not Available unknown_status NCT01716949
Neoadjuvant Chemoradiation With 5-FU(or Capecitabine) and Oxaliplatin Combined With Hyperthermia in Rectal Cancer treatment 1 / 2 unknown_status NCT05566249
A Study to Validate the Safety and Feasibility of ArtiSential in Colorectal Cancer Surgery Using Prospectively Constructed Multi-center Registry No drug interventions Not Available Not Available recruiting NCT04938336
Evaluation of a Decision Aid Tool in Rectal Cancer patiënts No drug interventions Not Available Not Available completed NCT02751736
The Effect Of Probiotics On Bowel Function Restoration After Ileostomy Closure In Patients With Rectal Cancer No drug interventions treatment Not Available unknown_status NCT00254436
A Double-Blind, Randomized, Placebo-Controlled Study of the Efficacy and Safety of Weekly Procrit Given to Gastric or Rectal Patients treatment 3 terminated NCT00904813
The Stockholm III Trial on Different Preoperative Radiotherapy Regimens in Rectal Cancer No drug interventions treatment Not Available completed NCT01142713
The Impact of Patient Positioning and Use of Belly Board on Small Bowel and Urinary Bladder Volume Irradiated in Patients Receiving Radiotherapy for Rectal Cancer: A Prospective Phase II Study No drug interventions treatment 2 unknown_status NCT05020613
Early and Late Removal of the Urinary Catheter After Rectum Resection No drug interventions prevention Not Available unknown_status NCT04135313
Induction and Consolidation Chemotherapy in Patients With Locally Advanced CRM-positive Rectal Cancer treatment 3 enrolling_by_invitation NCT04677413
Ultra-fractionated Radiotherapy for Rectal Cancer No drug interventions treatment 1 recruiting NCT04096118
Relationship Between Lymph Node Ratio and Survival Rate in Preoperative Chemoradiation Rectal Cancer Patients No drug interventions Not Available Not Available completed NCT02406118
Phase II Clinical Trial for the Evaluation of the Efficacy of Transanal TME No drug interventions treatment Not Available unknown_status NCT01366118
Study of Therapeutic Targets Tailored Ch and IMRT as Neoadjuvant Treatment in Rectal Carcinoma Patients treatment Not Available completed NCT03265418
BioXmark, Rectal Feasibility Trial No drug interventions treatment Not Available completed NCT02694718
A Study of Capecitabine Plus Oxaliplatin in Combination With Pre-operative Pelvic Radiotherapy in Rectal Cancer treatment 2 completed NCT06087718
Feasibility of the Maastro Applicator in Rectal Cancer No drug interventions treatment Not Available not_yet_recruiting NCT00847119
Xeloda and Bevacizumab to Treat Rectal Cancer treatment 2 completed NCT05476341
A Phase I Clinical Trial of Bevacizumab Injection treatment 1 completed NCT04643041
Watch and Wait in PD-1 Monoclonal Antibody Treated dMMR/MSI-H Distal Rectal Cancer No drug interventions treatment Not Available recruiting NCT06149741
Defunctioning Left-sided Colostomy in Low Anterior Resection for Rectal Cancer No drug interventions treatment Not Available recruiting NCT03258541
Organ-sparing With TraceIT® for Rectal Cancer Radiotherapy No drug interventions treatment Not Available terminated NCT05943041
Live Biotherapeutic Product GB104 Phase 1 Study in Colorectal Cancer No drug interventions treatment 1 recruiting NCT04836741
Chinese Surgical Robot Clinical Study on Rectectomy for Rectal Cancer No drug interventions treatment Not Available completed NCT01460641
Perfusion CT as a Predictor of Treatment Response in Patients With Rectal Cancer No drug interventions Not Available Not Available completed NCT02195141
Trial of Using SIB-IMRT in Preoperative Radiotherapy for Locally Advanced Rectum Cancer No drug interventions treatment 2 unknown_status NCT01941641
Colon Neoadjuvant FOLFOXIRI Study treatment 2 active_not_recruiting NCT05759741
Alterations of Gut Microbiome, Function, and Its Intervention After Defunctioning Ileostomy No drug interventions treatment 0 recruiting NCT01919541
Mechanistic Prehabilitation No drug interventions basic_science Not Available withdrawn NCT06229041
Total Neoadjuvant Treatment ±Immunotherapy for High Risk Locally Advanced Rectal Cancer (TNTi) treatment 3 recruiting NCT00956241
J-pouch Versus Side-to-end Coloanal Anastomosis After Preoperative Radiotherapy and Total Mesorectal Excision for Rectal Cancer No drug interventions treatment Not Available completed NCT06366841
Stigma and Psychological profilE in REctal-anal caNcer pAtients No drug interventions Not Available Not Available recruiting NCT02849717
Pre-Habilitation Exercise Intervention No drug interventions supportive_care Not Available completed NCT05539417
Snapshot Rectumcarcinoom 2016 No drug interventions Not Available Not Available completed NCT01999634
Monitoring by Microdialysis of Postoperative Complications After Proctectomy No drug interventions diagnostic 3 completed NCT02526134
Placing Trust in Endoscopic Ultrasonography: Impact on Planning Conformal Radiotherapy of Cancer of the Esophagus and Rectum No drug interventions treatment 2 completed NCT06216834
Quality of Life and Psychosocial Status of Young-onset Patients With Rectal Cancer No drug interventions Not Available Not Available recruiting NCT03393234
Intersphincteric Resection With or Without Intraoperative Radiation in Rectal Cancer No drug interventions treatment Not Available unknown_status NCT01659424
Phase II Trial of Preoperative High-dose-rate Endorectal Brachytherapy and FOLFOX Chemotherapy for Rectal Cancer No drug interventions treatment 2 withdrawn NCT04154124
Applying PET/MR in Rectal Cancer. No drug interventions diagnostic Not Available unknown_status NCT03049124
Exercise for Adults Diagnosed With Rectal Cancer No drug interventions supportive_care Not Available withdrawn NCT06455124
Short-course Radiotherapy Combined With CapeOx and PD-1 Inhibitor After Local Excision for High-risk Early Rectal Cancer (TORCH-LE) treatment 2 recruiting NCT04642924
SGM-101 in Locally Advanced and Recurrent Rectal Cancer No drug interventions treatment 2 / 3 unknown_status NCT06059924
Does the Management of Anastomotic Leakage After Low Rectal Resection Affect Survival No drug interventions Not Available Not Available completed NCT05381324
Fistula-associated Anal Adenocarcinoma No drug interventions Not Available Not Available completed NCT01269216
A Study of Neoadjuvant Chemoradiotherapy With 5-FU/Leucovorin (FL) vs. TS-1/Irinotecan in Patients With Locally Advanced Rectal Cancer treatment 2 completed NCT05957016
Neoadjuvant CIETAI With Concurrent Chemoradiotherapy in Local Advanced Rectal Cancer No drug interventions treatment 2 recruiting NCT06097416
Neoadjuvant Chemoradiotherapy Versus Total Neoadjuvant Therapy in the Treatment of T3 Rectal Cancer No drug interventions treatment 3 not_yet_recruiting NCT04838496
Induction Chemotherapy for Locally Advanced Rectal Cancer No drug interventions treatment 2 not_yet_recruiting NCT02277158
Phase I Study of CCRT as Adjuvant Treatment for Stage II/III Operable Rectal Cancer. No drug interventions treatment 1 unknown_status NCT02353858
Preoperative Radiochemotherapy With Hyperthermia for Locally Advanced Rectal Cancer treatment 2 completed NCT05215535
Liver Magnetic Resonance Imaging Before Treatment for Rectal Cancer. A Randomised Controlled Trial. No drug interventions diagnostic Not Available recruiting NCT04293835
Sigmoid Take-off, New Rectum Definition No drug interventions Not Available Not Available completed NCT04920435
Prediction of the Response to Neoadjuvant Radiation Chemotherapy Through Texture Analysis Derived From Medical Imaging No drug interventions Not Available Not Available completed NCT01985763
Genistein in Treatment of Metastatic Colorectal Cancer treatment 1 / 2 completed NCT02942563
Total Neoadjuvant Therapy for Locally Advanced Rectal Cancer treatment 2 unknown_status NCT02648386
Stem Cell Therapy Combined With NeuroRegen Scaffold™ in Patients With Erectile Dysfunction After Rectal Cancer Surgery No drug interventions treatment 1 / 2 unknown_status NCT00216086
Capecitabine + Irinotecan Followed by Combined Modality Capecitabine and Radiation in Locally Advanced Rectal Cancer treatment 2 terminated NCT05607186
Outcomes of Neoadjuvant Therapy for Rectal Cancer in a Tertiary Asian Institute No drug interventions Not Available Not Available completed NCT05052086
Magnetomotoric Ultrasound (MMUS) in Rectal Cancer No drug interventions diagnostic Not Available recruiting NCT03633539
Single-incision Versus Conventional Laparoscopic Surgery for Colorectal Cancer No drug interventions treatment Not Available withdrawn NCT02438839
Curative Chemoradiation of Low Rectal Cancer No drug interventions Not Available Not Available active_not_recruiting NCT04527939
Analysis of Extraperitoneal Rectal Neoplasms Between 3D Endorectal Ultrasonography and Magnification Chromoendoscopy No drug interventions treatment Not Available unknown_status NCT03840239
TNT to Increase the Clinical Complete Response Rate for Distal LARC treatment 2 active_not_recruiting NCT00467922
An Assessment of Goal-Directed Intraoperative Fluid Management in Hand Assisted Laparoscopic Colectomy treatment 3 completed NCT00257322
Cellular Immune Augmentation in Colon and Rectal Cancer No drug interventions treatment 2 completed NCT02460822
Developing an mHealth Application to Improve Cancer Chemotherapy Symptom Management No drug interventions supportive_care Not Available completed NCT03595722
Exploring HIFU as a Treatment for Rectal and Other Pelvic Cancers No drug interventions treatment Not Available unknown_status NCT05398822
The Role of TextRAd on Detection of Liver Metastasis in Rectal Cancer No drug interventions Not Available Not Available completed NCT05018325
Assessing Effect of Withdrawal Time on Adenoma Detection Rate for Screening Colonoscopy No drug interventions screening Not Available terminated NCT01790230
LifeSeal™ Preliminary Study in Subjects Undergoing Low Anterior Resection No drug interventions treatment Not Available completed NCT01206530
FOLFOX/Bevacizumab/Hydroxychloroquine (HCQ) in Colorectal Cancer treatment 1 / 2 completed NCT04379830
Preoperative Very Low Energy Diet for Obese Rectal Cancer Patients No drug interventions treatment Not Available withdrawn NCT03731130
Prospective Observational Trial to Evaluate Quality of Life After Neoadjuvant Radiation or Chemoradiation Followed by Surgery in Patients With Rectal Cancer No drug interventions Not Available Not Available recruiting NCT04561830
Open or Laparoscopic Mesolectal Excision in Low Rectum Cancer No drug interventions treatment Not Available completed NCT00182130
Quality Initiative in Rectal Cancer (QIRC) Trial No drug interventions educational_counseling_training Not Available unknown_status NCT05461248
Stoma Discharge Reinfusion After Sphincter Preservation for Middle and Low Rectal Cancer No drug interventions supportive_care Not Available not_yet_recruiting NCT04023448
The Effect of Different Reconstruction Methods on Anterior Resection Syndrome No drug interventions prevention Not Available unknown_status NCT00937248
Cone Beam Computed Tomography (CT) (CBCT) With and Without a Customized Vacuum Immobilization Device (CVID) No drug interventions treatment Not Available completed NCT00788957
Panitumumab Combination Study With Rilotumumab or Ganitumab in Wild-type Kirsten Rat Sarcoma Virus Oncogene Homolog (KRAS) Metastatic Colorectal Cancer (mCRC) treatment 1 / 2 completed NCT02603757
Effectiveness of High Dose Vitamin D Supplementation in Stage III Colorectal Cancer No drug interventions treatment Not Available completed NCT04696757
Non-OpeRative MANagement of Rectal Cancer Patients treatment 0 recruiting NCT05302557
Efferent Loop Stimulation Previous to Ileostomy Closure. Ileostim Trial. No drug interventions prevention Not Available unknown_status NCT03846726
Treatment Strategy for Rectal Cancer Patients With Complete Clinical Response No drug interventions Not Available Not Available completed NCT01552226
Compare Preperitoneal Analgesia to Epidural Analgesia for Pain Control After Colon and Rectal Surgery No drug interventions supportive_care Not Available unknown_status NCT05876026
MRI T1 Relaxation Time in Rectal Cancer No drug interventions Not Available Not Available recruiting NCT01836926
TaTME Versus Open Intersphincteric Resection After Neoadjuvant Concurrent Chemoradiotherapy. No drug interventions treatment Not Available completed NCT00952926
Watchful Waiting. An Observational Study of Patients With Rectal Cancer After Concomitant Radiation and Chemotherapy No drug interventions Not Available Not Available completed NCT05640726
The First-line Treatment of RCLM With RAS Mutation Was Local Short-course Radiotherapy (SCRT) + PD-1+ Standard Therapy treatment 2 not_yet_recruiting NCT01160926
Dual REctcal Angiogenesis or MEK Inhibition radioTHERAPY Trial treatment 1 terminated NCT01313026
Treatment of "Low Anterior Resection Syndrome" by Percutaneous Nerve Evaluation and Transanal Irrigation No drug interventions treatment Not Available terminated NCT03941366
Treatment of Adenocarcinoma of the Rectum With Transanal Local Excision for Complete Responders No drug interventions treatment Not Available recruiting NCT05338866
Chemotherapy Combined With High-dose Radiotherapy for Low Rectal Cancer Using MR Guided Linear Accelerator Not Available Not Available enrolling_by_invitation NCT01237665
IXO (Irinotecan, Xeloda, Oxaliplatin) in Rectal Cancer No drug interventions treatment 2 unknown_status NCT04339374
Ultrasound and Photoacoustic Imaging of Colon and Rectal Tumor Tissue No drug interventions Not Available Not Available recruiting NCT03161574
FOLFOXIRI Chemotherapy Alone as Neoadjuvant Treatment for Circumferential Radial Margin (CRM) Positive Rectal Cancer treatment 2 withdrawn NCT04278274
Post-Neoadjuvant Treatment MRI Based AI System to Predict pCR for Rectal Cancer No drug interventions Not Available Not Available recruiting NCT05241574
Planned Non-operative Management for Rectal Cancer No drug interventions treatment 2 unknown_status NCT01863420
The Effect of Bone Marrow-sparing Intensity-Modulated Radiotherapy to GI Cancer No drug interventions Not Available Not Available unknown_status NCT01351220
Community Dissemination of an Evidence-based Colorectal Cancer (CRC) Screening Intervention No drug interventions screening Not Available completed NCT04091620
Transanal Total Mesorectal Excision Versus Robotic Total Mesorectal Excision No drug interventions treatment Not Available unknown_status NCT04947020
dataBase for Analysis of Rectal Cancer Oncological Results Not Available Not Available active_not_recruiting NCT02217020
Neoadjuvant FOLFOXIRI Chemotherapy Alone for Locally Advanced Rectal Cancer treatment 2 completed NCT06236282
ArtiSential® for Rectal Cancer Surgery No drug interventions Not Available Not Available completed NCT03465982
Timing to Minimally Invasive Surgery After Neoadjuvant Chemoradiotherapy for Rectal Cancer No drug interventions treatment Not Available recruiting NCT05074082
Perineal Flap Reconstruction Following Surgery for Advanced Pelvic Malignancy No drug interventions Not Available Not Available completed NCT00846482
Exploratory Study Of The ERCC-1 Gene basic_science Not Available completed NCT01830582
Advanced MR Imaging for Early Biologic Tumor Changes to Neoadjuvant Chemoradiation Treatment for Rectal Cancer No drug interventions diagnostic Not Available completed NCT00607282
Efficacy of Udenafil After Radical Resection for Sigmoid Colon and Rectal Cancer treatment 2 completed NCT06390982
Organ Preservation With Tislelizumab and Total Neoadjuvant Therapy in Patients With Low Rectal Cancer: RELIEVE -01 Study treatment 2 not_yet_recruiting NCT03846882
FDG - PET / MRI in Patients With Rectal Cancer No drug interventions Not Available Not Available unknown_status NCT03589131
Robotic-assisted Versus Conventional Laparoscopic Approach for Rectal Cancer Surgery No drug interventions treatment Not Available completed NCT05806931
Sequential TAS-OX Alternating With TAS-IRI Plus Bevacizumab for Late-Line Metastatic Colorectal Cancer treatment 2 recruiting NCT05965531
Treating Locally Advanced Rectal Cancer With TAS-102 Chemotherapy Plus Neoadjuvant Radiotherapy treatment 2 not_yet_recruiting NCT06057831
PET/MRI in Rectal Cancer No drug interventions treatment 2 not_yet_recruiting NCT05877573
Toripalimab Combined With Neoadjuvant Chemoradiotherapy as First-line Treatment for Locally Advanced，High-Risk，MSS Rectal Cancer treatment Not Available recruiting NCT04404673
Urinary and Sexual Dysfunctions Evaluation After Rectal Resection No drug interventions Not Available Not Available unknown_status NCT01818973
Preoporative Bevacizumab, Radiation Therapy, and XELOX Chemotherapy for Locally Advanced Nonmetastatic Rectal Cancer treatment 2 unknown_status NCT04620473
Anlotinib Hydrochloride Combined With Capeox in the Neoadjuvant Treatment of Locally Advanced Rectal Cancer treatment 2 withdrawn NCT02188927
Effect of an Advanced Notification Letter on Screening Colonoscopy Participation No drug interventions screening Not Available unknown_status NCT06540027
The Effect of Minimally Invasive Surgery on Systemic Inflammatory Response in Rectal Cancer No drug interventions Not Available Not Available enrolling_by_invitation NCT06426927
PeLear CCC: Proyecto Latino Contra Cancer Colorectal No drug interventions other Not Available not_yet_recruiting NCT06536127
Prospective Monocentric Study Evaluating the Circulating NK Cells Phenotype and the ImmunoScore® in Patients With Non Metastatic Rectal Cancer No drug interventions other Not Available recruiting NCT06376227
Robotic-Assisted or Laparoscopic Radical Resection for Rectal Cancer With or Without Left Colic Artery Preservation No drug interventions Not Available Not Available completed NCT00457327
Pilot Study for Evaluation of the Need for Protective Ileostomy After Low Anterior Resection Due to Rectal Cancer No drug interventions treatment 2 terminated NCT05999227
68Ga-FAPI-04 PET Imaging in Early Response Evaluation of Rectal Cancer Patients Treated With Immunotherapy diagnostic Not Available recruiting NCT01938027
The Evaluation of the Safety and the Efficacy of Transanal Total Mesorectal Excision No drug interventions treatment Not Available completed NCT02602327
Tas-102 and Radioembolization With 90Y Resin Microspheres for Chemo-refractory Colorectal Liver Metastases treatment 1 completed NCT05328960
The Pandemic's Effect on Diagnosis and Treatment of Rectal Cancer No drug interventions Not Available Not Available recruiting NCT01257360
Panitumumab in Combination With Radiotherapy in Patients With Locally Advanced RAS Wildtype Rectal Cancer (Clinical Stages II and III) treatment 2 unknown_status NCT03299660
Avelumab With Chemoradiation in Locally Advanced Rectal Cancer treatment 2 completed NCT05111860
Neoadjuvant Bevacizumab + Chemotherapy Combined With Short-course Radiotherapy treatment 1 / 2 recruiting NCT00278694
Oxaliplatin and 5-FU Based Preoperative Chemoradiation treatment 2 completed NCT06239194
Dose Escalation and Dose Expansion Study of MDX2001 in Patients With Advanced Solid Tumors No drug interventions treatment 1 / 2 recruiting NCT00005094
Celecoxib to Prevent Colorectal Cancer in Patients Who Have Undergone Surgery to Remove Polyps prevention 3 completed NCT00849394
Evaluation of Protein in the Urine in Patients Receiving Bevacizumab No drug interventions Not Available Not Available completed NCT01786694
Feasibility of Microdialysis by Laparoscopy No drug interventions prevention 3 completed NCT00101894
Safety of AMG 706 Plus Panitumumab Plus Chemotherapy in the Treatment of Subjects With Metastatic Colorectal Cancer treatment 1 completed NCT03724591
Total Mesorectum Excision With Left Colic Artery Preservation for the Treatment of Rectal Cancer No drug interventions treatment Not Available unknown_status NCT01671891
Detection and Enumeration of Circulating Tumor Cells in Rectal Cancer Not Available Not Available unknown_status NCT02057991
Mindfulness-Based Exercise Video in Educating Hispanic/Latino Patients With Colorectal Cancer and Their Caregivers No drug interventions supportive_care Not Available terminated NCT02843191
Consolidation Chemotherapy for Locally Advanced Mid or Low Rectal Cancer After Neoadjuvant Concurrent Chemoradiotherapy No drug interventions treatment 3 recruiting NCT00122291
A Study of Preoperative Radiation Therapy and Capecitabine in Locally Advanced Rectal Cancer treatment 2 unknown_status NCT03826862
Lateral Lymph Node Dissection for Middle-low Rectal Cancer No drug interventions treatment Not Available unknown_status NCT00979680
Sphincter-preserving Surgery After Preoperative Treatment of Ultra-low Rectal Carcinoma No drug interventions treatment 3 completed NCT04795180
Pilot Randomized Evaluation of Butyrate Irrigation Before Ileostomy Closure on the Colonic Mucosa in Rectal Cancer Patients (BUTYCLO) No drug interventions prevention 2 completed NCT00819780
PEAK: Panitumumab Plus mFOLFOX6 vs. Bevacizumab Plus mFOLFOX6 for First Line Treatment of Metastatic Colorectal Cancer (mCRC) Patients With Wild-Type Kirsten Rat Sarcoma-2 Virus (KRAS) Tumors treatment 2 completed NCT03043729
mFOLFOX6 vs. mFOLFOX6 + Aflibercept as Neoadjuvant Treatment in MRI-defined T3-rectal Cancer treatment 2 completed NCT01477229
Quality of Life in RECTal Cancer - a Prospective Multicenter Cohort Study No drug interventions Not Available Not Available active_not_recruiting NCT01269229
A Trial of Neoadjuvant FOLFOX6 With Short Course Radiotherapy in Patients With Unresectable Rectal Cancer and Liver Metastasis No drug interventions treatment 2 completed NCT05450029
Neoadjuvant Chemoradiotherapy Plus Sintilimab for Intermediate/High Immunoscore Locally Advanced Rectal Cancer treatment 2 recruiting NCT06300489
Genotype-driven Weekly Irinotecan Liposomes in Combination With Capecitabine-based Neoadjuvant Chemoradiation for Locally Advanced Rectal Cancer treatment 1 recruiting NCT01224392
Simultaneous Integrated Boost Preoperative Radiotherapy for Rectum Cancer No drug interventions treatment 3 completed NCT06326892
Natural Orifice Specimen Extraction in Low Rectal Cancer Surgery No drug interventions Not Available Not Available recruiting NCT03085992
Folfoxiri Plus Bevacizumab Followed by Chemoradiotherapy Plus Bevacizumab in Patients With Resectable Rectal Cancer treatment 2 completed NCT06147492
Urinary Retention Following taTME VS laTME Total Mesorectal Excision for Rectal Cancer No drug interventions treatment Not Available completed NCT05028192
Mitochondria Preservation by Exercise Training: a Targeted Therapy for Cancer and Chemotherapy-induced Cachexia No drug interventions Not Available Not Available unknown_status NCT03581344
BReak Interval Delayed Surgery for Gastrointestinal Extraperitoneal Rectal Cancer No drug interventions treatment Not Available unknown_status NCT05374044
Establishment of MRI Model for pTRG in Rectal Cancer With Establishment of No drug interventions Not Available Not Available active_not_recruiting NCT01656044
Negative Pressure Therapy in Preventing Infection After Surgery in Patients With Colon, Rectal, Pancreatic, or Peritoneal Surface Cancer No drug interventions supportive_care Not Available completed NCT05331040
Radiomics in Rectal Cancer No drug interventions Not Available Not Available active_not_recruiting NCT04296240
Induction Chemotherapy for MRF-negative, Moderate-risk, Resectable Middle and Low Rectal Cancer treatment 2 unknown_status NCT05916040
Total Neoadjuvant Treatment of Rectal Cancer by MRI-guided Radiotherapy No drug interventions Not Available Not Available recruiting NCT02010567
Neoadjuvant Chemoradiotherapy With CRLX-101 and Capecitabine for Rectal Cancer treatment 1 / 2 terminated NCT01395667
Preoperative Chemoradiotherapy Utilizing Intensity Modulated Radiation Therapy in Combination With Bevacizumab-FOLFOX No drug interventions treatment 1 completed NCT04864067
No Operation After Short Course Radiotherapy Followed By Consolidation Chemotherapy In Locally Advanced Rectal Cancer treatment 2 recruiting NCT04674267
Resilience and Equity in Aging, Cancer, and Health (REACH) No drug interventions health_services_research Not Available recruiting NCT01653301
Preoperative Downstaging of Extraperitoneal T3 Rectal Cancer: XELOXRT Versus XELACRT. A Multicenter, Phase III Study No drug interventions treatment 3 unknown_status NCT00695201
Hepatic Arterial Infusion With Floxuridine and Dexamethasone in Combination With Intravenous Oxaliplatin Plus Irinotecan in Patients With Unresectable Hepatic Metastases From Colorectal Cancer treatment 1 completed NCT03204201
Validation of ICG to Identify the Urethra During Rectal Surgery other 1 / 2 terminated NCT06380101
Evaluating a Nonessential Amino Acid Restriction (NEAAR) Medical Food With Total Neoadjuvant Therapy for Locally Advanced Rectal Cancer (LARC) No drug interventions other Not Available recruiting NCT04340401
Total Neoadjuvant Treatment Plus SHR1210 for High-risk Rectal Cancer and Biomarker Screening Base on Neoantigen treatment 2 unknown_status NCT02371304
Rectal Preserving Treatment for Early Rectal Cancer. A Multi-centred Randomised Trial of Radical Surgery Versus Adjuvant Chemoradiotherapy After Local Excision for Early Rectal Cancers treatment 3 unknown_status NCT01609504
ELRR by TEM Versus Laparoscopic TME in iT2N0M0 SMALL LOW RECTAL CANCER No drug interventions treatment 3 completed NCT03541304
High Dose Radiotherapy for the Treatment of Rectal Cancer No drug interventions Not Available Not Available completed NCT04103372
Pre-therapeutic MRI Assessment of Early Stage Rectal Cancer and Significant Rectal Polyps to Avoid Major Resectional Surgery: A New Approach to the Management of Early Stage Rectal Cancer. No drug interventions treatment Not Available not_yet_recruiting NCT04949672
Pathology Assessment of Mesorectal Fascia After TME by Laparoscopic, Open, TransAnal and Robotic Approaches (LOTARTME) No drug interventions Not Available Not Available completed NCT06249672
Longterm Functional Outcomes in Patients Undergoing Organ Preserving Treatment for Rectal Cancer With or Without Local Excision After Chemoradiotherapy No drug interventions Not Available Not Available recruiting NCT01736072
RObotic Versus LAparoscopic Resection for Rectal Cancer No drug interventions treatment Not Available completed NCT01569672
Ohio Patient Navigator Research Program No drug interventions health_services_research Not Available completed NCT04095468
Organ-preserving Management in Patients With Complete or Near-complete Tumour Response After Preoperative Radio(Chemo)Therapy for Rectal Cancer No drug interventions Not Available Not Available recruiting NCT02550769
Study of NOTES-TME Versus L-LAR in Rectal Cancer No drug interventions treatment Not Available completed NCT04612569
Feasibility and Impact of a Prehabilitation and Rehabilitation Program for the Continuity of Care in Severe Low Anterior Resection Syndrome. No drug interventions Not Available Not Available unknown_status NCT00230646
Promoting Physical Activity After Colorectal Cancer No drug interventions Not Available 3 completed NCT05807646
Reduced Dissemination of Tumor Cells With Primary Ligation of the Inferior Mesenteric Vein in Rectal Cancer Patients. No drug interventions treatment Not Available not_yet_recruiting NCT05040646
The Development of a Patient Reported Outcomes Measure Committed to the Watch-and-wait Program for Rectal Cancer No drug interventions Not Available Not Available completed NCT06189846
Lumeneye Rectoscope for Assessment on Tumor Response After Total Neoadjuvant Treatment in Rectal Cancer No drug interventions Not Available Not Available recruiting NCT06314646
Transanal Transection and Single-stapled Anastomosis (TTSS) in Rectal Cancer Patients No drug interventions Not Available Not Available recruiting NCT00701012
Comparison of Low and High Ligation in the Rectal Cancer No drug interventions treatment Not Available completed NCT01379612
Ultrasound Elastography in Patients With Rectal Cancer No drug interventions Not Available Not Available completed NCT01211210
Neoadjuvant FOLFOX6 Chemotherapy With or Without Radiation in Rectal Cancer treatment 2 / 3 unknown_status NCT03609710
Application of Left Colic Artery Preservation, Anastomotic Reinforcing Sutures and Transanal Tube in Robotic Low Anterior Resection No drug interventions treatment Not Available unknown_status NCT05943210
The Radiation Oncology-Biology Integration Network (ROBIN) Molecular Characterization Trial (MCT) of Standard Short Course Radiotherapy for Rectal Cancer No drug interventions basic_science Not Available recruiting NCT05772481
Interest of PET-MRI in the Evaluation of the Response After Neoadjuvant Treatment of Locally Advanced Rectal Adenocarcinoma No drug interventions Not Available Not Available recruiting NCT01186081
Comparison of Preoperative and Postoperative Radiotherapy and Capecitabine in Locally Advanced Rectal Cancer No drug interventions treatment 3 completed NCT04147481
Effects of Abdominal Nerve Block on Postoperative Recovery in Patients Undergoing Gastrointestinal Surgery No drug interventions treatment Not Available unknown_status NCT05667181
The Application Value of da Vinci Linear Cutting Stapler SureForm in Robotic Anus Preserving Surgery for Rectal Cancer No drug interventions treatment Not Available recruiting NCT03039595
Ploidy and Stroma in Early Rectal Cancer No drug interventions Not Available Not Available completed NCT03082495
Exercise During and After Neoadjuvant Rectal Cancer Treatment No drug interventions supportive_care Not Available completed NCT05538195
Safety and Efficacy of CEA-targeted CAR-T for CEA-positive Advanced Malignant Solid Tumors No drug interventions treatment 1 / 2 recruiting NCT02979795
Translational Research in Identifying Molecular Mechanisms for Rectal Cancer Metastasis No drug interventions Not Available Not Available unknown_status NCT01444495
Randomized Clinical Trial on Preoperative Radiotherapy 25 Gy in Rectal Cancer No drug interventions treatment Not Available completed NCT04543695
A Study of Total Neoadjuvant Therapy for High-risk Locally Advanced Rectal Cancer No drug interventions treatment 2 active_not_recruiting NCT02292914
Prospective Analysis of Robot-Assisted Surgery No drug interventions treatment Not Available unknown_status NCT05462314
Intestinal Microbiome, Oral Microbiome, and Whole Blood Transcriptome Analyses in Gastrointestinal Malignancies No drug interventions Not Available Not Available recruiting NCT04080414
Home-based HIIT to Improve CRC Survivorship: Feasibility and Relationship With Novel Surrogate Biomarkers of CRC Recurrence No drug interventions other Not Available completed NCT01717014
Radial Reload Open LAR Case Series No drug interventions treatment Not Available terminated NCT01423214
A Trial to Assess Robot-assisted Surgery and Laparoscopy-assisted Surgery in Patients With Mid or Low Rectal Cancer No drug interventions treatment 3 unknown_status NCT00835055
Expression of Molecular Markers Before and After Neo-adjuvant Chemoradiotherapy in Rectal Cancer No drug interventions Not Available Not Available withdrawn NCT03895255
Selective sPlenic flExure Mobilization for Low colorEctal Anastomosis After D3 lYmph Node Dissection (Speedy Trial) No drug interventions treatment Not Available unknown_status NCT04017455
Neoadjuvant Treatment in Rectal Cancer With Radiotherapy Followed by Atezolizumab and Bevacizumab (TARZAN) treatment 2 unknown_status NCT04088955
A Digimed Oncology PharmacoTherapy Registry No drug interventions Not Available Not Available unknown_status NCT04109755
Neo-adjuvant Pembrolizumab and Radiotherapy in Localised MSS Rectal Cancer treatment 2 recruiting NCT03107650
Preoperative Prediction Model of Pathological Outcomes (Mesorectum Quality and Positive Circumferential Resection Margin) in Patients With Mid-low Rectal Cancer No drug interventions Not Available Not Available completed NCT00411450
Panitumumab Regimen Evaluation in Colorectal Cancer to Estimate Primary Response to Treatment treatment 2 completed NCT05010850
SafeHeal Colovac Colorectal Anastomosis Protection Device Evaluation (SAFE-2) Pivotal Study No drug interventions treatment Not Available terminated NCT02140723
p53 and Response to Preoperative Radiotherapy for T2 and T3 No drug interventions Not Available Not Available unknown_status NCT05772923
Organ Preservation in Rectal Cancer: Contact X-ray Brachytherapy vs Extending the Waiting Interval and Local Excision No drug interventions treatment Not Available recruiting NCT04636008
Sintilimab Plus Hypofractionated Radiotherapy for MSI-H/dMMR Rectal Cancer treatment 1 / 2 recruiting NCT06405308
Robotic Natural Orifice Specimen Extraction Surgery Versus Robotic Transabdominal Specimen Extraction Surgery for Early-Stage Rectal Cancer No drug interventions Not Available Not Available completed NCT06194708
Reasons for Non-reversal of Temporary Stomas After Surgeries of Mid-low Rectal Cancer （NORESTO Study） No drug interventions Not Available Not Available recruiting NCT04759638
Short Running Head Obesity in Rectal Cancer Patients No drug interventions Not Available Not Available completed NCT03941938
ReAL Trial (Rectal Anastomotic seaL) No drug interventions treatment Not Available unknown_status NCT02550743
BrUOG 302:BYL719, Capecitabine and Radiation for Rectal Cancer: A Brown University Oncology Research Group Study treatment 1 terminated NCT06290960
Patient Reported Outcomes Following Cancer of the Rectum No drug interventions Not Available Not Available enrolling_by_invitation NCT02130427
A Volume, Motion, and Anatomically Adaptive Approach to Photon and Proton Beam Radiotherapy No drug interventions other Not Available completed NCT01340508
Preoperative Concurrent Chemotherapy and Intensity Modulated Radiotherapy (IMRT) in Locally Advanced Rectal Cancer No drug interventions treatment 2 unknown_status NCT04916990
Improving Care for Rural Patients With Solid Tumors No drug interventions health_services_research Not Available recruiting NCT06601985
Exploring the Effect of Colonic J-pouch in Anorectal Preservation Surgery for Ultra-low Rectal Cancer. No drug interventions Not Available Not Available active_not_recruiting NCT06530303
Biological Tumor Infiltrating Lymphocytes Therapy With Immunotherapy for Colon and Rectum Cancer treatment 1 / 2 not_yet_recruiting NCT06311279
End to End Versus Side to End Anastomosis After Anterior Resection of Cancer Rectum No drug interventions treatment Not Available recruiting NCT02966054
Self-monitoring and Reminder Texts to Increase Physical Activity After Cancer: a Pilot Randomized Controlled Trial No drug interventions supportive_care Not Available completed NCT02997553
Fluorescence for Sentinel Lymph Node Identification in Cancer Surgery diagnostic 3 completed NCT03071198
Clinical Effect of Neoadjuvant Hierarchical Treatment Based on Chemotherapy No drug interventions treatment Not Available unknown_status NCT05411783
Low Tie Versus High Tie of the Inferior Mesenteric Vein During Colorectal Cancer Surgery: A Randomized Clinical Trial No drug interventions prevention Not Available unknown_status NCT02966509
Engagement of Patients With Advanced Cancer No drug interventions health_services_research Not Available completed NCT06567756
Conformal Sphincter-Preservation Operation Versus InterSphincteric Resection on Anal Function in Low Rectal Cancer No drug interventions treatment Not Available not_yet_recruiting NCT04443985
A Cohort of Predictive Factor of Pathologic Complete Response After Preoperative Neoadjuvant in Rectum Cancer No drug interventions Not Available Not Available completed NCT05201885
Oncological Differences Between Transanal and Laparoscopic Total Mesorectal Excision for Rectal Cancer. No drug interventions Not Available Not Available recruiting NCT02738359
Efficacy of Colonoscopy, Colon Capsule and Fecal Immunological Test for Colorectal Cancer Screening No drug interventions Not Available Not Available recruiting NCT04405206
Total Neoadjuvant Therapy Followed by 'Watch and Wait' Approach or Organ Preservation for Low-risk Rectal Cancer Not Available Not Available unknown_status NCT03445936
PRELOOP Trial: Synthetic Versus Biological Mesh for Prevention of Incisional Hernia After Loop-ileostomy Closure No drug interventions prevention Not Available active_not_recruiting NCT03345563
Project HERO: Health Empowerment & Recovery Outcomes No drug interventions supportive_care Not Available active_not_recruiting NCT00576563
Rectal Study: Value of Repeated FDG-PET-CT Scans in Rectal Cancer treatment Not Available completed NCT05400122
Natural Killer (NK) Cells in Combination With Interleukin-2 (IL-2) and Transforming Growth Factor Beta (TGFbeta) Receptor I Inhibitor Vactosertib in Cancer treatment 1 recruiting NCT06458725
Assessment of DW-MRI Measures : Reproducibility and Repeatability in Pelvic Imaging on MR-Linac With Healthy Volunteers No drug interventions other Not Available not_yet_recruiting NCT05900648
Regorafenib and XmAb20717 in Treatment of High-risk Patients With Colorectal Cancer With Radiographic Occult Molecular Residual Disease After End of Established Definitive Therapy (RX-CROME) treatment 2 withdrawn NCT02958566
Multimodal Narcotic Limited Perioperative Pain Control With Colorectal Surgery supportive_care 4 unknown_status NCT02079389
The Value of Laparoscopic Ultrasound in Patients Undergoing Laparoscopic Resection for Cancer of the Colon or Rectum No drug interventions diagnostic Not Available completed NCT00509444
Cancer Prevention and Treatment Among African American Older Adults: Treatment Trial No drug interventions treatment 3 completed NCT02973672
Phase I of SGM-101 in Patients With Cancer of the Colon, Rectum or Pancreas No drug interventions diagnostic 1 / 2 completed NCT05715255
Adaptive Symptom Self-Management Immunotherapy Study No drug interventions supportive_care Not Available recruiting NCT03065855
Removal Time of Urinary Catheter After Laparoscopic Anterior Resection of the Rectum No drug interventions treatment Not Available unknown_status NCT02458664
BASE HSP110 : A New Therapeutic Target and a New Marker for Prognosis of Type MSI Colorectal Cancer No drug interventions Not Available Not Available unknown_status NCT03252821
Effects of High-intensity Training Compared to Resistance Training in Cancer Patients Undergoing Radiotherapy No drug interventions treatment Not Available completed NCT00909987
Study of Neoadjuvant CT With Selective Radiotherapy in Patients With Intermediate-Risk Cancer Rectum treatment 2 completed NCT04371198
Patient-Derived Organoids for Rectal Cancer No drug interventions other Not Available completed NCT03699761
The Role of Pelvic Peritonization in Laparoscopic or Robotic Low Anterior Resection No drug interventions treatment Not Available recruiting NCT05652361
Machine Learning-based Surgical Guidance System for Robot-assisted Rectal Surgery No drug interventions other Not Available recruiting NCT00336856
Irinotecan and Cetuximab for Colorectal Cancer as Second Line Therapy treatment 2 completed NCT03257332
Determining Early Development of Faecal Incontinence and Anorectal Muscle Function After Surgery for Rectal Cancer. No drug interventions Not Available Not Available withdrawn NCT02216149
Effects of S-1 and Capecitabine on Coronary Artery Blood Flow treatment 2 terminated NCT05388513
Evaluating Factors Affecting Survival in Colon and Rectum Cancer No drug interventions Not Available Not Available completed NCT06116019
Online Adaptive Radiotherapy Using a Novel Linear Accelerator (ETHOS) No drug interventions Not Available Not Available recruiting NCT05493930
A Lymph Node Metastasis Predictor (LN-MASTER) in Rectal Cancer No drug interventions Not Available Not Available completed NCT00964457
Treatment of Patients With Advanced Rectum Cancer With Capecitabine and Oxaliplatin Before, Under and After Radiation and With Adding Cetuximab to K-RAS Wild-type Patients treatment 2 unknown_status NCT03843957
Effectiveness and Implementation of mPATH-CRC No drug interventions other Not Available completed NCT02423226
Computed Tomography-guided Brachytherapy Plus Chemotherapy for Locally Recurrent Rectum Cancer treatment 2 completed NCT05245565
Effects of Modified Precision Functional Sphincter-Preserving Surgery (PPS) on Ultralow Rectal Cancer No drug interventions Not Available Not Available recruiting NCT05305820
Perioperative Exercise and Nutritional Optimisation Prehabilitation Before Surgery for Patients With Peritoneal Malignancy No drug interventions health_services_research Not Available active_not_recruiting NCT04755920
SGM-101 in Colorectal Brain Metastases. No drug interventions treatment 2 recruiting NCT06066931
Reconstruction of the Pelvic Floor and Perineal Wound After Rectal ELAPE No drug interventions treatment Not Available not_yet_recruiting NCT00409994
Safety Study of Rapamycin Administered Before and During Radiotherapy to Treat Rectum Cancer treatment 1 / 2 completed NCT04745091
MRI Split Scar Sign as a Predictor to Complete Pathologic Response After Neoadjuvant Chemoradiation in Rectal Cancer No drug interventions Not Available Not Available unknown_status NCT01979029
Study of the Preservation of the Left Colic Artery on Rectum Cancer Surgery No drug interventions treatment Not Available completed NCT04744792
QoL of Colorectal Cancer Patients and Spouses No drug interventions Not Available Not Available completed NCT04015804
Robotic Low Rectum Anterior Resection No drug interventions other Not Available active_not_recruiting NCT05201872
Bacteriological Differences Between Transanal and Laparoscopic Total Mesorectal Excision for Rectal Cancer. No drug interventions Not Available Not Available unknown_status NCT00379743
Partnership for Healthy Seniors No drug interventions screening Not Available completed