Malignant Melanoma (DBCOND0029825)

Identifiers

Synonyms
Malignant Melanomas / Melanoma, Malignant / Malignant melanoma / Malignant melanoma (morphologic abnormality) / Melanoma / Malignant melanoma (disorder) / Melanoma malignant

Associated Data

Indicated Drugs and Targets
DrugDescriptionTargets
Interferon alfa
An immunomodulator used to treat hepatitis B and C as well as certain types of cancer including cutaneous T-cell lymphoma and renal cell carcinoma.
Interferon alfa-2b
A form of recombinant human interferon used to treat hepatitis B and C infection, genital warts, hairy cell leukemia, follicular lymphoma, malignant melanoma, and AIDs-related Kaposi's sarcoma.
Technetium Tc-99m albumin colloid
A radiopharmaceutical comprising human albumin nano colloidal particles and Tc-99m used in scintigraphy of bone and lymph node structures.
No drug targets
Technetium Tc-99m sulfur colloid
A radiopharmaceutical diagnostic agent used for the localization of lymph nodes, evaluation of peritoneovenous (LeVeen) shunt patency, imaging areas of functioning reticuloendothelial cells, and gastrointestinal imaging.
No drug targets
Vindesine
A vinca alkaloid derived from vinblastine used for various types of malignancies, but mainly acute lymphocytic leukemia (ALL).
Clinical Trials
IdentifierTitleDrug(s)PurposePhaseStatus
NCT05928962
An Exploratory Single-arm Study: PD-1 With Recombinant Human Adenovirus Type 5 Injection for Malignant Melanomastreatment1enrolling_by_invitation
NCT06299163
NM32-2668 in Adult Patients With Selected Advanced Solid TumorsNo drug interventionstreatment1recruiting
NCT03454282
Impact of Dietary Intervention on Tumor Immunity: the DigesT TrialNo drug interventionstreatmentNot Availableunknown_status
NCT05551117
A Study of Vobramitamab Duocarmazine in Participants With Metastatic Castration Resistant Prostate Cancer and Other Solid Tumorstreatment2active_not_recruiting
NCT06332755
Study to Evaluate LB-LR1109 for the Treatment of Solid TumorsNo drug interventionstreatment1recruiting
NCT06613230
Improved Early Diagnosis in Female Pelvic Cancer With OC DetectNo drug interventionsNot AvailableNot Availablerecruiting
NCT01271803
A Study of Vemurafenib and GDC-0973 (Cobimetinib) in Participants With BRAFV600E Mutation-Positive Metastatic Melanomatreatment1completed
NCT01962103
Study to Find a Safe Dose and Show Early Clinical Activity of Weekly Nab-paclitaxel in Pediatric Patients With Recurrent/ Refractory Solid Tumorstreatment1 / 2completed
NCT00651703
Safety and Immunogenicity of CYT004-MelQbG10 Vaccine With and Without Adjuvant in Advanced Stage Melanoma Patientstreatment2completed
NCT02935790
Selective HDAC6 Inhibitor ACY-241 in Combination With Ipilimumab and Nivolumabtreatment1completed
NCT00963664
Evaluation of Interferon-Lovastatin Therapy for Malignant Melanomatreatment2withdrawn
NCT00616564
Phase II Trial of (IL-2) With Priming and (GM-CSF) in Patients With Advanced MelanomaNo drug interventionstreatment2completed
NCT04382664
UV1 Vaccination Plus Nivolumab and Ipilimumab in Treatment of Melanomatreatment2completed
NCT00179764
Immunoablative Mini Transplant (Hematopoietic Peripheral Blood Stem Cell Transplant [HPBSC])No drug interventionstreatmentNot Availablecompleted
NCT01253564
A Study of RO5185426 in Previously Treated Melanoma Patients With Brain Metastasestreatment2completed
NCT01543464
Peptide Vaccine and Temozolomide for Metastatic Melanoma Patientstreatment2terminated
NCT00949702
A Study of Vemurafenib in Previously Treated Patients With Metastatic Melanomatreatment2completed
NCT02828202
Follow-up of a National Cohort of Melanoma Resectable Stage II, Stage III or IV Patients or Unresectable PrimaryNo drug interventionsNot AvailableNot Availablerecruiting
NCT02223884
A Study to Evaluate the Efficacy of Docetaxel and Carboplatin in Metastatic Malignant Melanoma Failed First-Line Dacabazine or Temozolomide Contained Therapytreatment2completed
NCT06294379
Shared Decision Making in Melanoma Patients Receiving Adjuvant TherapyNo drug interventionsNot AvailableNot Availablerecruiting
NCT04879654
Toripalimab Combined With Radiotherapy and Chemotherapy in the Treatment of SNMM After Endoscopic SurgeryNo drug interventionstreatment2recruiting
NCT00034554
Study of gp75 Vaccine in Patients With Stage III and IV MelanomaNo drug interventionstreatment1completed
NCT00864253
A Trial of ABI-007 Versus Dacarbazine in Previously Untreated Patients With Metastatic Malignant Melanomatreatment3completed
NCT04460053
Neurofilament Light Protein in Peripheral Blood Used as a Biomarker for Neurotoxicity After Isolated Limb Perfusion.No drug interventionsdiagnosticNot Availablecompleted
NCT00087477
A Pilot Study of Pivanex in Patients With Malignant Melanomatreatment1 / 2terminated
NCT00733798
A Safety and Efficacy Study of Intravenous 131I-TM601 in Adult Patients With Malignant Melanomatreatment1 / 2terminated
NCT00350597
GM-CSF as Adjuvant Therapy of MelanomaNo drug interventionstreatment2completed
NCT00601861
Effect of rIL-21 on Metastases in Lymph Nodes in Melanoma Skin Cancertreatment2terminated
NCT00715793
Combination of Decitabine and Temozolomide in the Treatment of Patients With Metastatic Melanomatreatment1 / 2completed
NCT02535078
Phase 1b/2 Study of the Combination of IMCgp100 With Durvalumab and/or Tremelimumab in Advanced Cutaneous Melanomatreatment1 / 2withdrawn
NCT03607578
Test of Interventions to Prevent Skin Cancer Among Danes on Vacation in High UV Index Sunny DestinationsNo drug interventionspreventionNot Availablecompleted
NCT04543188
A FIH Study of PF-07284890 in Participants With BRAF V600 Mutant Solid Tumors With and Without Brain Involvementtreatment1terminated
NCT01164007
A Study of Bevacizumab (Avastin) in Combination With Dacarbazine in Participants With Unresectable/Metastatic Melanomatreatment2completed
NCT06206707
FMT in Checkpoint Inhibitor-mediated Diarrhea and ColitisNo drug interventionstreatmentNot Availablerecruiting
NCT00052156
Vaccine Therapy for Patients With Stage IV Melanomatreatment3unknown_status
NCT00044356
Phase II Trial of Allovectin-7® for Metastatic MelanomaNo drug interventionstreatment2completed
NCT03966456
Real World Study of Four PD-1 Agents in ChinaNo drug interventionsNot AvailableNot Availableunknown_status
NCT01359956
Fotemustine and Dacarbazine Versus Dacarbazine +/- Alpha Interferon in Advanced Malignant Melanomatreatment3completed
NCT05389085
Fast Track Diagnosis of Skin Cancer by Advanced Imaging Technologies and Tumour TapestrippingNo drug interventionsdiagnosticNot Availablecompleted
NCT03383237
Clinical Study of Apatinib as the Second-line Therapy in Malignant Melanomatreatment2unknown_status
NCT01321437
Study of the Anti-Angiogenesis Agent Axitinib in Patients With Stage III Malignant Melanomatreatment2completed
NCT05098132
Phase 1a/1b Study of STK-012 Monotherapy and in Combination With Pembrolizumab in Patients With Solid Tumorstreatment1recruiting
NCT00855452
Activated Allogeneic Lymphocytes for Induction Graft Versus Tumor Effect in Metastatic Solid TumorsNo drug interventionstreatment2completed
NCT00327600
Safety and Efficacy Trial of Imexon Plus DTIC in Advanced Malignant Melanomatreatment1 / 2completed
NCT02537600
Vemurafenib and Cobimetinib Combination in BRAF Mutated Melanoma With Brain Metastasistreatment2completed
NCT02661100
A Trial of CDX-1401 in Combination With Poly-ICLC and Pembrolizumab, in Previously Treated Advanced Solid Tumor Patientstreatment1 / 2withdrawn
NCT01455259
Phase I/IIa AdCD40L Immunogene Therapy for Malignant Melanoma and Other Solid TumorsNo drug interventionstreatment1 / 2completed
NCT04123470
A Phase I/II Trial Investigating LOAd703 in Combination With Atezolizumab in Malignant Melanomatreatment1 / 2completed
NCT02902042
Encorafenib + Binimetinib + Pembrolizumab in Patients With Unresectable or Metastatic BRAF V600 Mutant Melanomatreatment1 / 2completed
NCT01656642
A Phase 1b Study of Atezolizumab in Combination With Vemurafenib or Vemurafenib Plus Cobimetinib in Participants With BRAFV600-Mutation Positive Metastatic Melanomatreatment1completed
NCT02938299
Neoadjuvant L19IL2/L19TNF- Pivotal Studytreatment3recruiting
NCT01001299
A Pharmacokinetic Study of RO5185426 in Combination With a Drug Cocktail in Patients With Metastatic Melanomatreatment1completed
NCT02143999
An Observational Study of BRAF Inhibitors Effectiveness in Patients With Newly Diagnosed Metastatic MelanomaNo drug interventionsNot AvailableNot Availablecompleted
NCT01137006
An Open-Label, Dose-Escalation Study of IMC-20D7S In Participants With Malignant MelanomaNo drug interventionstreatment1completed
NCT00323206
Phase I Trial of Intratumoral pIL-12 Electroporation in Malignant MelanomaNo drug interventionstreatmentNot Availablecompleted
NCT00370136
Sentinel Node With Ultrasound Contrast in MelanomaNo drug interventionsdiagnosticNot Availablecompleted
NCT00498836
Multicentre, Dose Finding, Ph II,CP-4055 in Comb. With Sorafenib - Patients With Metastatic Malignant Melanomatreatment2completed
NCT02523313
Immunotherapy With Nivolumab or Nivolumab Plus Ipilimumab vs. Double Placebo for Stage IV Melanoma w. NEDtreatment2completed
NCT00978913
Transfected Dendritic Cell Based Therapy for Patients With Breast Cancer or Malignant Melanomatreatment1completed
NCT04889118
Safety and Efficacy Study of Pembrolizumab (MK-3475) Combined With Lenvatinib (MK-7902/E7080) as First-line Intervention in Adults With Advanced Melanoma (MK-7902-003/E7080-G000-312/LEAP-003)-China Extension Studytreatment3active_not_recruiting
NCT00358319
Phase I/II Trial of Valproic Acid and Karenitecin for Melanomatreatment1 / 2terminated
NCT01689519
A Study Comparing Vemurafenib Versus Vemurafenib Plus Cobimetinib in Participants With Metastatic Melanomatreatment3completed
NCT01124734
High Dose Interleukin-2 Followed by Intermittent Low Dose Temozolomide in Patients With Melanomatreatment2completed
NCT00204516
Vaccination With Tumor mRNA in Metastatic Melanoma - Fixed Combination Versus Individual Selection of Targeted AntigensNo drug interventionstreatment1 / 2completed
NCT02275416
Safety of UV1 Vaccination in Combination With Ipilimumab in Patients With Unresectable or Metastatic Malignant Melanomatreatment1 / 2active_not_recruiting
NCT00111696
Study of the Tumor Saturation and Biological Activity of MEDI-522 (Abergrin) in Patients With Advanced Malignant Melanomatreatment1completed
NCT02296996
Dabrafenib and Trametinib for BRAF-inhibitor Pretreated Patientstreatment2completed
NCT01253096
Intratumoral Application of L19IL2 in Patients With Malignant Melanomatreatment2completed
NCT00287196
Immediate Radiotherapy or Observation After Surgery for Melanoma Involving Lymph NodesNo drug interventionstreatment3completed
NCT05293496
A Study of MGC018 in Combination With MGD019 in Participants With Advanced Solid Tumorstreatment1recruiting
NCT00145158
Immunization With 8 Peptides Mixed With CpG 7909 or Montanide ISA51 in Patients With Metastatic Cutaneous Melanomatreatment1 / 2terminated
NCT02410863
Biopsy- and Biology-driven Optimization of Targeted Therapy in Subjects With Advanced Melanomatreatment2terminated
NCT04648163
Suction Drain in Axillary Lymph Node Dissection for Malignant MelanomaNo drug interventionsNot AvailableNot Availablecompleted
NCT00336986
Efficacy Study of IL-21 to Treat Metastatic MelanomaNo drug interventionstreatment2completed
NCT05664139
Recombinant Human Adenovirus Type 5 Injection Combined With PD-1 Monoclonal Antibody and Nab-paclitaxel in the Treatment of Patients With Liver Metastases From Malignant Melanomatreatment2not_yet_recruiting
NCT05037825
The Gut Microbiome and Immune Checkpoint Inhibitor Therapy in Solid TumorsNo drug interventionsNot AvailableNot Availablerecruiting
NCT00052130
Vaccine Therapy for Patients With Stage III Melanomatreatment3unknown_status
NCT01990248
An Observational Safety Study in Zelboraf (Vemurafenib)-Treated Patients With BRAF-V600 Mutation-Positive Unresectable or Metastatic Melanoma (ZeSS)No drug interventionsNot AvailableNot Availablecompleted
NCT04079166
SCIB1 and iSCIB1+ in Melanoma Patients Receiving Nivolumab With Ipilimumab or SCIB1 With Pembrolizumab (The SCOPE Study)treatment2recruiting
NCT00306566
Safety and Immunogenicity of a Melan-A VLP Vaccine in Early Stage Melanoma PatientsNo drug interventionsNot Available1 / 2completed
NCT03448666
ECT-Pembrolizumab in Patients With Unresectable Melanoma With Superficial or Superficial and Visceral Metastasestreatment2recruiting
NCT03278665
4SC-202 in Combination With Pembrolizumab in Patients Primary Refractory/Non-responding to Prior Anti-PD-1 Therapytreatment1 / 2completed
NCT04913220
A Study of SAR444245 Combined With Cemiplimab for the Treatment of Participants With Various Advanced Skin Cancers (Pegathor Skin 201)treatment1 / 2active_not_recruiting
NCT00235482
Intratumoural Administration of Coxsackievirus A21 for the Control of Malignant Melanoma (PXS-X02)treatment1completed
NCT04217382
Pre Transplantation MelanomaNo drug interventionsNot AvailableNot Availablecompleted
NCT06270082
Study of IK-595 in RAS- or RAF-altered Advanced TumorsNo drug interventionstreatment1recruiting
NCT01024231
Dose-escalation Study of Combination BMS-936558 (MDX-1106) and Ipilimumab in Subjects With Unresectable Stage III or Stage IV Malignant Melanomatreatment1completed
NCT04126876
A Randomized Controlled Phase II Trial With Intradermal IMO-2125 in Pathological Tumor Stage (p) T3-4 cN0M0 Melanomatreatment2recruiting
NCT01002560
The Identification of Novel Prognostic Markers in MelanomaNo drug interventionsNot AvailableNot Availableunknown_status
NCT01636960
A Study of Pegylated Interferon Alfa-2b (MK-4031) as an Adjuvant Treatment in Japanese Patients With Malignant Melanoma (MK-4031-370)No drug interventionstreatment1terminated
NCT00204594
Local Treatment of Metastatic Melanoma With Autologous Lymphocytes and the Bispecific Antibody rM28No drug interventionstreatment1 / 2completed
NCT02718391
Complementary Vaccination With Dendritic Cells Pulsed With Autologous Tumor Lysate in Resected Stage III and IV Melanoma Patients.No drug interventionstreatment2terminated
NCT06209580
AMT-253 in Patients With Advanced Solid TumoursNo drug interventionstreatment1 / 2recruiting
NCT01264380
A Study of the Effect of Food on the Pharmacokinetics of Single Dose RO5185426 And the Safety And Efficacy of Continuous Administration in Patients With BRAF V600E Mutation-Positive Metastatic Melanomatreatment1completed
NCT01006980
A Study of Vemurafenib (RO5185426) in Comparison With Dacarbazine in Previously Untreated Patients With Metastatic Melanoma (BRIM 3)treatment3completed
NCT03649529
Treatment of Malignant Melanoma With GPA-TriMAR-T Cell TherapyNo drug interventionstreatment0unknown_status
NCT03563729
Melanoma Metastasized to the Brain and Steroidstreatment2recruiting
NCT02709889
Rovalpituzumab Tesirine in Delta-Like Protein 3-Expressing Advanced Solid Tumorstreatment1 / 2terminated
NCT00299689
Phase II Trial of Ontak With Metastatic Melanomatreatment2completed
NCT02650492
Immunostimulating Interstitial Laser Thermotherapy in Malignant MelanomaNo drug interventionstreatmentNot Availableterminated
NCT04282044
Study of CRX100 as Monotherapy and in Combination With Pembrolizumab in Patients With Advanced Solid Malignanciestreatment1recruiting
NCT01278940
Trial of Vaccine Therapy With mRNA- Transfected Dendritic Cells in Patients With Advanced Malignant MelanomaNo drug interventionstreatment1 / 2completed
NCT03084640
Phase 1B Study Evaluating Alternative Routes of Administration of CMP-001 in Combination With Pembrolizumab in Participants With Advanced Melanomatreatment1completed
NCT01065467
Panobinostat (LBH589) in Patients With Metastatic Melanomatreatment1completed
NCT00924001
Chemotherapy Followed by Infusion of DMF5 Cells to Treat Metastatic Melanomatreatment1 / 2terminated
NCT00513604
Phase II Study of Short-Term Cultured Anti-Tumor Autologous Lymphocytes After Lymphocyte-Depleting Chemotherapy in Metastatic Melanomatreatment2completed
NCT02612168
Melanoma Image Analysis Algorithm (MIAA) Validation StudyNo drug interventionsdiagnosticNot Availablecompleted
NCT01435369
Safety, Tolerability and Efficacy Study of the Monoclonal Antibody, CT-011, in Patients With Metastatic Melanomatreatment2completed
NCT00060710
CP-461 in the Treatment of Patients With Advanced MelanomaNo drug interventionstreatment2terminated
NCT01910181
A Study of Vemurafenib (Zelboraf) in Chinese Participants With BRAF V600 Mutation-Positive Unresectable or Metastatic Melanomatreatment1completed
NCT06553781
A Single-arm, Multicenter Clinical Study of Fruquintinib Combined With Cadonilimab Injection and Temozolomide in Second-line and Subsequent Treatment of Advanced MelanomatreatmentNot Availablenot_yet_recruiting
NCT03034395
Study of 1cm Versus 2cm Margins for the Surgical Treatment of cT2N0M0 MelanomaNo drug interventionstreatmentNot Availablecompleted
NCT00535314
Study of Two Dose Levels of RTA 402 in Patients With Advanced Malignant Melanomatreatment2withdrawn
NCT03538314
UV1 Vaccine With Pembrolizumab for Patients With Unresectable or Metastatic MelanomaNo drug interventionstreatment1completed
NCT01077050
SciBase International Melanoma Pivotal StudyNo drug interventionsdiagnosticNot Availablecompleted
NCT00991250
SentoClone® Compared to Reference Treatment in Advanced Malignant Melanomatreatment2unknown_status
NCT03780608
This Study is a Phase II Study of AZD6738 in Combination With Durvalumab in Patients With Solid Tumor (Cohort A (N=30): GC Who Have Failed Secondary Chemotherapy Treatments Regimen; Cohort B (B=30): Melanoma Patients Who Have Failed to IO)treatment2unknown_status
NCT00179608
Study of the Combination of Lenalidomide and DTIC (Dacarbazine) in Patients With Metastatic Malignant Melanoma Previously Untreated With Systemic Chemotherapytreatment1completed
NCT00911443
Thymosin Alpha 1, Interferon Alpha, or Both, in Combination With Dacarbazine in Patients With Malignant Melanomatreatment2completed
NCT01522664
A Study of DEDN6526A in Patients With Metastatic or Unresectable MelanomaNo drug interventionstreatment1completed
NCT06150664
A Phase 1 of CTX-8371 in Patients With Advanced MalignanciesNo drug interventionstreatment1recruiting
NCT02050321
A Phase II Study of Vemurafenib Combined With Acitretin in Patients With Advanced Melanomatreatment2terminated
NCT00104884
FR901228 in Treating Patients With Unresectable Stage III or Stage IV Malignant Melanomatreatment2terminated
NCT01704287
Study of Pembrolizumab (MK-3475) Versus Chemotherapy in Participants With Advanced Melanoma (MK-3475-002/P08719/KEYNOTE-002)treatment2completed
NCT00405587
Safety Study of PLX4032 in Patients With Solid Tumorstreatment1completed
NCT02574533
Pilot Study of Vigil™ + Pembrolizumab for Advanced Melanomatreatment1completed
NCT02434354
A Tissue Collection Study of Pembrolizumab (MK-3475) in Subjects With Resectable Advanced Melanomatreatment1completed
NCT00142454
NY-ESO-1 Protein Vaccine With Imiquimod in Melanoma (Adjuvant Setting)treatment1completed
NCT02303951
Neoadjuvant Vemurafenib + Cobimetinib + Atezolizumab in Melanoma: NEO-VCtreatment2terminated
NCT01227551
A Study of Intratumoral CAVATAK™ in Patients With Stage IIIc and Stage IV Malignant Melanoma (VLA-007 CALM )treatment2completed
NCT03178851
Cobimetinib (Targeted Therapy) Plus Atezolizumab (Immunotherapy) in Participants With Advanced Melanoma Whose Cancer Has Worsened During or After Treatment With Previous Immunotherapy and Atezolizumab Monotherapy in Participants With Previously Untreated Advanced Melanomatreatment1completed
NCT00306553
Safety and Immunogenicity of a Melan-A VLP Vaccine in Advanced Stage Melanoma PatientsNo drug interventionsNot Available2completed
NCT04229277
Fast Track Diagnosis of Skin Cancer by Advanced ImagingNo drug interventionsdiagnosticNot Availablecompleted
NCT01588847
Anesthesia and Cancer Recurrence im Malignant MelanomaNo drug interventionstreatmentNot Availableunknown_status
NCT01696045
Phase 2 Study of Ipilimumab in Children and Adolescents (12 to < 18 Years) With Previously Treated or Untreated, Unresectable Stage III or Stage lV Malignant Melanomatreatment2terminated
NCT00145145
Immunization With the MAGE-3.A1 Peptide Mixed With the Adjuvant CpG 7909 in Patients With Metastatic Melanomatreatment1 / 2terminated
NCT05144698
RAPA-201 Therapy of Solid Tumorstreatment1 / 2recruiting
NCT01167998
Early Diagnosis of Malignant Transformation of Pigmentary Skin LesionsNo drug interventionsNot AvailableNot Availableunknown_status
NCT06560905
Preoperative Planning With PSMA-PET in Melanoma Surgery TrialNo drug interventionsdiagnostic2not_yet_recruiting
NCT01307397
A Study of Vemurafenib in Participants With Metastatic Melanomatreatment3completed
NCT04884997
A Study of Toripalimab or Combining With Temozolomide(iv) in the Treatment of Advanced/Metastatic Malignant Melanomatreatment2recruiting
NCT04763083
First in Human Study of NVG-111 in Relapsed/Refractory ROR1+ MalignanciesNo drug interventionstreatment1recruiting
NCT02889861
IMCgp100-401 Rollover Studytreatment2terminated
NCT00963261
Quality of Life and Psychological Well-being in Patients With Malignant MelanomaNo drug interventionsdiagnosticNot Availableunknown_status
NCT02938728
Definition of an Immune Signature Predictive of Anti-PD1 (Programmed Death-1) Antibody in the Treatment of Advanced MelanomaNo drug interventionsNot AvailableNot Availableunknown_status
NCT00204607
Intradermal Vaccination With Stabilized Tumor mRNA - a Clinical Phase I/II Trial in Melanoma PatientsNo drug interventionstreatment1 / 2completed
NCT03060356
Autologous T Cells Expressing MET scFv CAR (RNA CART-cMET)No drug interventionstreatment0terminated
NCT05756556
T3011 in Combination With Cobimetinib in Patients With Advanced Melanomatreatment2suspended
NCT04904185
ImmPACT Expanded Multiple Antigen Specific Endogenously Derived T Cells (MASE-T) to Patients With Metastatic Melanomatreatment1terminated
NCT01017185
Study of HF10 in Patients With Refractory Head and Neck Cancer or Solid Tumors With Cutaneous and/or Superficial LesionsNo drug interventionstreatment1completed
NCT01898585
An Open-Label Study of Zelboraf (Vemurafenib) in Patients With Braf V600 Mutation Positive Metastatic Melanomatreatment4completed
NCT04593485
Anti-PD-1 Antibody in the Treatment of Patients With Malignant Melanoma of the Female Genital Tracttreatment2unknown_status
NCT00710515
Study to Assess the Effect of Dosing AZD6244 HydSulfate in the Presence and Absence of Food in Patients With Advanced Solid Malignanciestreatment1completed
NCT00441337
A Study of MDX-1106 in Patients With Selected Refractory or Relapsed Malignanciestreatment1completed
NCT05172232
Diagnostic Precision of the AI Tool Dermalyzer to Identify Malignant Melanomas in Subjects Seeking Primary Care for Melanoma-suspected Cutaneous LesionsNo drug interventionsNot AvailableNot Availablecompleted
NCT00039000
Study of Heat Shock Protein-Peptide Complex (HSPPC-96) Versus IL-2/DTIC for Stage IV Melanomatreatment3completed
NCT02829775
A Study of Continued Treatment Among Participants Who Have Responded to Peginterferon Alfa-2a (Pegasys®) or Recombinant Interferon Alfa-2a (Roferon-A®) in Prior Clinical Studiestreatment2 / 3completed
NCT00108875
Survivin Peptide Vaccination for Patients With Advanced Melanoma, Pancreatic, Colon and Cervical CancerNo drug interventionstreatment1 / 2unknown_status
NCT01378975
A Study of Vemurafenib in Metastatic Melanoma Participants With Brain Metastasestreatment2completed
NCT05089370
Oral Decitabine/Cedazuridine (DEC-C) in Combination With Nivolumab for Patients With Mucosal Melanomatreatment1 / 2recruiting
NCT02673970
Biomarkers for the Activity of Immune Checkpoint Inhibitor Therapy in Patients With Advanced MelanomaNo drug interventionsNot AvailableNot Availablerecruiting
NCT02186249
Expanded Access Program With Nivolumab in Combination With Ipilimumab in Patients With Tumors Unable to be Removed by Surgery or Metastatic MelanomaNot AvailableNot Availableno_longer_available
NCT04285749
Prevention of Recurrence and Metastasis in Genetically High-Risk Melanomastreatment0withdrawn
NCT03197636
Co-stimulatory Markers and Vitamin D Status in Anti-PD1 Treated Melanoma PatientsNot AvailableNot Availablecompleted
NCT01248936
A Study of RO5185426 in Patients With Metastatic Melanomatreatment2completed
NCT04924413
L-TIL Plus Tislelizumab as First-line Treatment in Advanced Malignant Melanomatreatment2terminated
NCT01107418
A Pharmacokinetic/Pharmacodynamic Study of RO5185426 in Previously Treated Patients With Metastatic Melanomatreatment1completed
NCT01559818
A Long Term Follow up Study for Patients Who Previously Took Part in the Phase I Study IMM-101-001treatment1 / 2terminated
NCT03409419
PET Imaging of the Immune System Using Analog ProbesNot AvailableNot Availablecompleted
NCT03653819
High Intensity Interval Training (HIIT) for Patients With Cancer-related Lymphedema in the Lower LimbsNo drug interventionssupportive_careNot Availablecompleted
NCT00145041
Pharmacokinetic Study of Liposomal Vincristine in Patients With Malignant Melanoma & Hepatic Dysfunctiontreatment1completed
NCT02331134
Tissue and Hematopoietic/Mesenchymal Stem Cell for Humanized Xenograft Studies in Melanoma and Squamous Head and Neck Cancerbasic_scienceNot Availableactive_not_recruiting
NCT03545334
Lymph Node Identification in Skin Malignancy Using ICG Transcutaneously StudyNo drug interventionsdiagnosticNot Availablecompleted
NCT02068196
A National Phase IV Study With Ipilimumab for Patients With Advanced Malignant Melanoma.treatment4active_not_recruiting
NCT04074096
Binimetinib Encorafenib Pembrolizumab +/- Stereotactic Radiosurgery in BRAFV600 Melanoma With Brain Metastasistreatment2active_not_recruiting
NCT03903458
Tinostamustine and Nivolumab in Advanced Melanomatreatment1unknown_status
NCT03158935
The ACTIVATE (Adoptive Cell Therapy InVigorated to Augment Tumor Eradication) Trialtreatment1completed
NCT03236935
Phase Ib of L-NMMA and Pembrolizumabtreatment1active_not_recruiting
NCT00116363
Safety and Efficacy Study of INGN 241 Gene Therapy in Patients With In Transit MelanomaNo drug interventionstreatment2unknown_status
NCT01288963
IL-2 "SELECT" Tissue Collection Protocol in Patients With Advanced MelanomaNot AvailableNot Availablecompleted
NCT03820986
Safety and Efficacy Study of Pembrolizumab (MK-3475) Combined With Lenvatinib (MK-7902/E7080) as First-line Intervention in Adults With Advance Melanoma (MK-7902-003/E7080-G000-312/LEAP-003)treatment3active_not_recruiting
NCT01898039
Modified Melanoma Vaccine for High Risk or Low Residual Disease Patientstreatment1 / 2unknown_status
NCT06265025
GM103 Intratumoral Injection in Patients With Locally Advanced, Unresectable, Refractory and/or Metastatic Solid Tumorstreatment1 / 2recruiting
NCT04223648
Programmed Cell Death 1 + Selected Cell Therapy With Durvalumab (MEDI4736) and Tremelimumab in Metastatic Melanomabasic_science0withdrawn
NCT00232726
Clinical Study of Previously Untreated Patients With Malignant Melanomatreatment2completed
NCT03551626
Study of Dabrafenib+Trametinib in the Adjuvant Treatment of Stage III BRAF V600+ Melanoma After Complete Resection to Evaluate the Impact on Pyrexia Related Outcomestreatment3completed
NCT00540566
Optical Biopsy of Human Skin in Conjunction With Laser TreatmentNo drug interventionsNot AvailableNot Availablecompleted
NCT02784366
GI Complications in Cancer Immunotherapy PatientsNo drug interventionsNot AvailableNot Availableunknown_status
NCT02897765
A Personal Cancer Vaccine (NEO-PV-01) w/ Nivolumab for Patients With Melanoma, Lung Cancer or Bladder Cancertreatment1completed
NCT04253574
Comparison of PET/CT and Ultrasound in Staging of Malignant MelanomaNo drug interventionsNot AvailableNot Availablecompleted
NCT00966173
International Melanoma Algorithm Training Study - IMATSNo drug interventionsdiagnosticNot Availablecompleted
NCT01069627
A Study of Avastin (Bevacizumab) in Combination With Fotemustine in Patients With Metastatic Melanomatreatment2completed
NCT00294476
IVIG in the Treatment of Metastatic Cancers of the Prostate, Colon and MelanomaNo drug interventionstreatment2unknown_status
NCT05478876
Carbon Ion Radiation Therapy in the Treatment of Mucous Melanomas of the Female Lower Genital TractNo drug interventionstreatmentNot Availablerecruiting
NCT00087776
Study of Taxoprexin Injection vs. Dacarbazine in Patients With Metastatic Malignant MelanomaNo drug interventionstreatmentNot Availablecompleted
NCT01744860
Comparison of In-House Methods and Cobas BRAF V600 Mutation Assay in Melanoma Tumor SamplesNo drug interventionsNot AvailableNot Availablecompleted
NCT02452294
Buparlisib in Melanoma Patients Suffering From Brain Metastases (BUMPER)treatment2unknown_status
NCT00539591
Phase II Study Incorporating Pegylated Interferon In the Treatment For Children With High-Risk Melanomatreatment2active_not_recruiting
NCT01164891
A Pharmacokinetic and Metabolism Study of 14C-labeled RO5185426 on Patients With Metastatic Melanomatreatment1completed
NCT01211262
Study to Assess the Tolerability of a Bispecific Targeted Biologic IMCgp100 in Malignant Melanomatreatment1completed
NCT02902029
Evaluating the Efficacy and Safety of a Sequencing Schedule of Cobimetinib Plus Vemurafenib Followed by Immunotherapy With an Anti- PD-L1 Antibody in Patients With Unresectable or Metastatic BRAF V600 Mutant Melanomatreatment2completed
NCT03332589
E6201 Plus Dabrafenib for the Treatment of Metastatic Melanoma Central Nervous System Metastases (CNS)treatment1terminated
NCT04293289
Boron Neutron Capture Therapy Using CICS-1 and SPM-011 for Malignant Melanoma and AngiosarcomaNo drug interventionstreatmentNot Availablecompleted
NCT00086489
CP-675,206 In Patients With Advanced Melanomatreatment2completed
NCT03689192
Arginase-1 Peptide Vaccine in Patients With Metastatic Solid TumorsNo drug interventionstreatment1completed
NCT02071940
PLX3397 KIT in Acral aNd mucOsal Melanomatreatment2completed
NCT02459067
ImmuniCell® in Patients With Advanced CancersNo drug interventionstreatment2terminated
NCT01307267
A Study Of PF-05082566 As A Single Agent And In Combination With Rituximabtreatment1completed
NCT00483301
A Phase II Trial OF Carboplatin, ABI-007 (Abraxane) And Sorafenib (BAY 43-9006) in Metastatic Melanomatreatment2completed
NCT00631072
In Vitro Expanded Autologous Invariant Natural Killer Cells in CancerNo drug interventionstreatment1completed
NCT00324272
Post-Operative Drainage Following Lymph Node Dissectiontreatment4completed
NCT02644369
Study of the Effects of Pembrolizumab in Patients With Advanced Solid Tumorstreatment2active_not_recruiting
NCT05304546
Overcoming Primary Resistance to Immunotherapy in Metastatic Melanomatreatment2not_yet_recruiting
NCT04547946
Observational Study for Melanoma Adjuvant Treatment With Tafinlar® + Mekinist® (Dabrafenib + Trametinib)Not AvailableNot Availablecompleted
NCT03116412
A Randomized Trial to Assess the Role of Imaging During Follow up After Radical Surgery of High Risk MelanomaNo drug interventionsdiagnosticNot Availablerecruiting
NCT00300612
Vaccine Treatment for Advanced Malignant MelanomaNo drug interventionstreatment1 / 2completed
NCT01138410
Study of a DNA Immunotherapy to Treat Melanomatreatment1 / 2terminated
NCT01264081
Lapatinib in Stage IV Melanoma With ERBB4 Mutationstreatment2terminated
NCT02316795
Fluorescence Imaging in Sentinel Lymph Node Biopsy for Breast Cancer and MelanomaNo drug interventionsdiagnostic0completed
NCT01586195
Study Of Zelboraf (Vemurafenib) in Patients With Locally-Advanced, Unresectable, Stage IIIc Or Metastatic Melanoma and Activating Exon 15 BRAF Mutations Other Than V600Etreatment2terminated
NCT00826995
Comparison of Video-Based Versus Written Patient Education on MelanomaNo drug interventionsNot AvailableNot Availablecompleted
NCT00862914
Immunohistochemical Expression Patterns of microRNA Processing Enzyme Dicer in Cutaneous Malignant Melanoma, Benign and Dysplastic Melanocytic NaeviNo drug interventionsNot AvailableNot Availablecompleted
NCT01557114
Study of Radiotherapy Administered in Combination With Ipilimumab in Patients With Unresectable Stage III or Stage IV Advanced Malignant Melanomatreatment1terminated
NCT04452214
A Study of the Safety and Tolerance of CAN04 and Pembrolizumab in Combination With and Without Carboplatin and Pemetrexed in Subjects With Solid Tumorstreatment1completed
NCT02272855
A Study of Combination Treatment With HF10 and Ipilimumab in Patients With Unresectable or Metastatic Melanomatreatment2completed
NCT05130255
GD2-SADA:177Lu-DOTA Complex in Patients With Solid Tumors Known to Express GD2No drug interventionstreatment1recruiting
NCT00729950
Study of MDX-010 in Subjects With Unresectable Stage III or Stage IV Malignant Melanomatreatment1completed
NCT01519323
BRIM-P: A Study of Vemurafenib in Pediatric Patients With Stage IIIC or Stage IV Melanoma Harboring BRAFV600 Mutationstreatment1terminated
NCT01247623
Trial With Telomerase Peptide Vaccine In Combination With Temozolomide in Patients With Advanced Malignant MelanomaNot Available1 / 2completed
NCT01480323
A Phase II Study to Evaluate Safety and Efficacy of Combined Treatment With Ipilimumab and Intratumoral Interleukin-2treatment2completed
NCT00135408
A Study of MDX-010 (BMS-734016) Administered With or Without Prophylactic Oral Budesonidetreatment2completed
NCT00203008
A Survey Study to See if Patients Diagnosed With Parkinson's Disease Have Higher Incidence of MelanomaNo drug interventionsNot AvailableNot Availablecompleted