Technetium Tc-99m sulfur colloid is a radiopharmaceutical diagnostic agent used for the localization of lymph nodes, evaluation of peritoneovenous (LeVeen) shunt patency, imaging areas of functioning reticuloendothelial cells, and gastrointestinal imaging. Following injection or oral administration, single photon emission computer tomography (SPECT) imaging is performed using a gamma camera to detect technetium-99m decay.
- Mechanism
- Curator reviewed
Following injection or oral administration, single photon emission computer tomography (SPECT) imaging is performed using a gamma camera to detect technetium-99m decay. This is possible as Technetium-99m decays by isomeric transition to technetium-99 through the release of a gamma ray.
- Primary indication
- Technetium 99m sulfur colloid is indicated as a diagnostic agent in adults for the following tests: localization of lymph nodes draining a primary tumor in patients with breast cancer or malignant melanoma; and evaluation of...Curator reviewed · 6 structured indications
- Formula / weight
- S8Tc · 355.39 g/mol (avg)
- First approval
- United States, 1978
- Also known as
- Technetium (99mTc) sulfur colloid · Technetium 99m sulfur colloid · Technetium Sulfur Colloid · Technetium Tc 99m sulfur colloid · Technetium99m sulfur colloid
Resolves to
FJTPHHNWVXNMEK-NLQOEHMXSA-NSMILES[99Tc].S1SSSSSSS1What you can answer from here — as of November 19, 2025
Which other approved drugs treat the same conditions as Technetium Tc-99m sulfur colloid, and which companies have late-stage candidates in those indications?
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