Superficial Basal Cell Carcinoma (DBCOND0032565)

Identifiers

Synonyms

Superficial basal cell carcinoma / Superficial basal cell carcinoma (disorder) / Superficial basal cell carcinoma (morphologic abnormality) / Basal cell carcinoma / Carcinoma basal cell / Basalioma / Basal cell epithelioma / Rodent ulcer / Basal cell carcinoma (morphologic abnormality) / Basal cell carcinoma of skin (disorder) / Carcinoma, Basal Cell

Associated Data

Indicated Drugs and Targets

Drug	Description	Targets
Fluorouracil	A pyrimidine analog used to treat basal cell carcinomas, and as an injection in palliative cancer treatment.	Thymidylate synthasetarget Cytochrome P450 1A2enzyme Thymidine phosphorylaseenzyme Albumincarrier Cytochrome P450 2C9enzyme Dihydropyrimidine dehydrogenase [NADP(+)]enzyme Uridine phosphorylase 1enzyme Uridine phosphorylase 2enzyme DNAtarget RNAtarget Cytochrome P450 2A6enzyme Cytochrome P450 2C8enzyme Methylenetetrahydrofolate reductase (NADPH)enzyme Thymidylate synthaseenzyme Uridine 5'-monophosphate synthaseenzyme Amidophosphoribosyltransferaseenzyme Solute carrier family 22 member 7transporter Equilibrative nucleoside transporter 1transporter Broad substrate specificity ATP-binding cassette transporter ABCG2transporter ATP-binding cassette sub-family C member 3transporter ATP-binding cassette sub-family C member 4transporter ATP-binding cassette sub-family C member 5transporter Thyroxine-binding globulincarrier Thymidylate synthasetarget Dihydropyrimidine dehydrogenase [NADP(+)]target Telomerase reverse transcriptasetarget
Imiquimod	A toll-like receptor 7 agonist used to treat non hyperkeratotic, non hypertrophic actinic keratosis, basal cell carcinoma, genital or perianal warts, and condyloma acuminata.	Toll-like receptor 7target Toll-like receptor 8target Cytochrome P450 3A4enzyme

Clinical Trials

Identifier	Title	Drug(s)	Purpose	Phase	Status
NCT04552990	Use of Jet-injection in Photodynamic Therapy for Basal Cell Carcinoma	No drug interventions	treatment	2	active_not_recruiting
NCT01325688	PEP005 Gel - Evaluation of the Safety and Efficacy of Ingenol Mebutate Gel on a Superficial Basal Cell Carcinoma on the Trunk or Extremities	Ingenol mebutate	treatment	2	completed
NCT03012009	Laser Assisted Drug Delivery in the Treatment of Superficial Non Melanoma Skin Cancer: a Randomized Controlled Trial	Epinephrine Lidocaine Methyl aminolevulinate	treatment	Not Available	completed
NCT00189306	Open-label Study to Evaluate Clearance of Superficial Basal Cell Carcinoma After Use of Imiquimod 5% Cream	Imiquimod	treatment	3	completed
NCT00469417	Metvix Photodynamic Therapy (PDT) Versus Cryotherapy in Participants With Primary Superficial Basal Cell Carcinoma	Methyl aminolevulinate	treatment	3	completed
NCT04470726	Safety and Efficacy of AIV001 on Low Risk Basal Cell Carcinoma	No drug interventions	treatment	1 / 2	completed
NCT05713760	Proof of Concept Study to Access Superficial Basal Cell Carcinoma in Adults	Tirbanibulin	treatment	2	completed
NCT05628714	A Patient Decision Aid for Patients With Superficial Basal Cell Carcinoma	No drug interventions	Not Available	Not Available	completed
NCT00604890	Dose-Ranging Clinical Trial of Topical Creams Containing API 31510 for the Treatment of Superficial Basal Cell Carcinoma	Ubidecarenone	treatment	1 / 2	completed
NCT02270645	Randomized Pilot Study of Treatment for BCC Using the Multiplex 595/1064 nm Laser	No drug interventions	treatment	Not Available	completed
NCT05381597	5-Fluorouracil and Calcipotriene for Treatment of Low Grade Skin Cancer	Calcipotriol Fluorouracil	treatment	2 / 3	recruiting
NCT01491711	Superficial Basal Cell Carcinoma Treatment With Topical Photodynamic Therapy With Fractionated 5-aminolevulinic Acid 20% Versus Two Stage Methylaminolevulinate	Aminolevulinic acid Methyl aminolevulinate	treatment	4	unknown_status
NCT00432185	To Determine the Maximum Tolerated Dose Level (MTD) of PEP005 Topical Gel in Patients With sBCC	Ingenol mebutate	treatment	2	completed
NCT04744935	Optical Coherence Tomography Guided Laser Treatment of Basal Cell Carcinoma	No drug interventions	treatment	Not Available	recruiting
NCT05157763	A Study to Evaluate the Safety and Efficacy of EscharEx (EX-02) in the Treatment of Basal Cell Carcinoma	No drug interventions	treatment	1 / 2	unknown_status
NCT00994240	Cure Rates of Superficial Basal Cell Carcinoma (BCC) EDC	No drug interventions	treatment	Not Available	terminated
NCT03573401	Study to Evaluate the Safety and Efficacy of BF-200 ALA (Ameluz®) and BF-RhodoLED® in the Treatment of Superficial Basal Cell Carcinoma (sBCC) With Photodynamic Therapy (PDT).	Aminolevulinic acid	treatment	3	active_not_recruiting